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The map label for this gene is qorA [H]

Identifier: 157371296

GI number: 157371296

Start: 3366759

End: 3367766

Strand: Direct

Name: qorA [H]

Synonym: Spro_3056

Alternate gene names: 157371296

Gene position: 3366759-3367766 (Clockwise)

Preceding gene: 157371295

Following gene: 157371299

Centisome position: 61.79

GC content: 58.23

Gene sequence:

>1008_bases
ATGTCAGCCAACCCAGCGCTGCCCAACACCATGAAAGTCGTCGAAATCAGCCAGCCTGGCGAACCAGAGGTTCTGATTAG
CAGCCAAAGACCGCTGCCAACCCTGCAACAGGGAGAAATTCTGGTGAAGGTTGCTGCCGCCGGCGTTAACCGCCCTGATG
TGATGCAACGCCGCGGCCAATACGCACCGCCTGCTGGCGCATCGGACATTCCTGGTCTGGAGATCGCCGGTACCGTAGTC
GCTATCGGTATTGGGGTACAAAATTACGCCATCGGCGACGCGGTTTGCGCCCTGATTGCCGGCGGCGGTTACGCAGAATA
CTGCAAAGTACATGAAAGCAATGCGCTGCCGGTACCCGAGGGCTTTAGCCTGATTGAAGCGGCGGCGATCCCGGAAACCT
TCTTTACCGTGTGGGTCAACGTGTTCCAACGCGGGCACCTTAAGGCTGGCGAAACCGTTTTGATCCACGGCGGAACCTCC
GGTATCGGCACTGTCGCCACCCTGCTGGCGAAAGCCTTTTGCGCCCGGGTGATCACCACCGTCGGCTCCGAAGAAAAGCG
CCAGGCCAGTCTGGCATTGGGTGCCGATGTGGCGATTAACTACCGCAACGAAGATTTTGTTGAACAGACCCAGCGCGCGA
CTAACGGCAAGGGAGCCGACGTGATTGTCGATCTGATTGCCGGTGATTACGTGGCGAAGAACTACCAGGCGGCGGCGATG
GACGGGCGCATTGTGCAAATCGGCACCCAGAACGGCGTGGTGAAGGAACTGAACCTGATGCCACTGCTGATCAAGCGCCT
GACCCATACCGGCTCGACCTTGCGGGCACGCAGCGTGGAAGATAAAGCGCAAATTGCCGCTGATTTACGCCAGAAGGTGT
GGCCGCTACTGGAGCGCGGCGCATTAAAACCGCAGATATTCAAAACCTTCCCGCTGGATCAGGCCGCGGAAGCCCATGCG
CTGATGGAGTCCAGTCAGCATATCGGTAAAATCATGCTGACTATCTAG

Upstream 100 bases:

>100_bases
ACATTCTCCCTTCGGCATTTATGTAAGATAAAACATGAATTACAGCAGGCGGTTACCTACACTGGTTACTGCGCCTGAAC
GCCAACTGAGGAGAATCACC

Downstream 100 bases:

>100_bases
GTCACACGCCCCCCGCAGCAGGGGTCGCGGGGGGATGTTTTCAGTTGCCTGGGGTGTGGACCTCTTCCGGCGTGGAGTCG
GTATTGGCTAACTTCTCTTG

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSANPALPNTMKVVEISQPGEPEVLISSQRPLPTLQQGEILVKVAAAGVNRPDVMQRRGQYAPPAGASDIPGLEIAGTVV
AIGIGVQNYAIGDAVCALIAGGGYAEYCKVHESNALPVPEGFSLIEAAAIPETFFTVWVNVFQRGHLKAGETVLIHGGTS
GIGTVATLLAKAFCARVITTVGSEEKRQASLALGADVAINYRNEDFVEQTQRATNGKGADVIVDLIAGDYVAKNYQAAAM
DGRIVQIGTQNGVVKELNLMPLLIKRLTHTGSTLRARSVEDKAQIAADLRQKVWPLLERGALKPQIFKTFPLDQAAEAHA
LMESSQHIGKIMLTI

Sequences:

>Translated_335_residues
MSANPALPNTMKVVEISQPGEPEVLISSQRPLPTLQQGEILVKVAAAGVNRPDVMQRRGQYAPPAGASDIPGLEIAGTVV
AIGIGVQNYAIGDAVCALIAGGGYAEYCKVHESNALPVPEGFSLIEAAAIPETFFTVWVNVFQRGHLKAGETVLIHGGTS
GIGTVATLLAKAFCARVITTVGSEEKRQASLALGADVAINYRNEDFVEQTQRATNGKGADVIVDLIAGDYVAKNYQAAAM
DGRIVQIGTQNGVVKELNLMPLLIKRLTHTGSTLRARSVEDKAQIAADLRQKVWPLLERGALKPQIFKTFPLDQAAEAHA
LMESSQHIGKIMLTI
>Mature_334_residues
SANPALPNTMKVVEISQPGEPEVLISSQRPLPTLQQGEILVKVAAAGVNRPDVMQRRGQYAPPAGASDIPGLEIAGTVVA
IGIGVQNYAIGDAVCALIAGGGYAEYCKVHESNALPVPEGFSLIEAAAIPETFFTVWVNVFQRGHLKAGETVLIHGGTSG
IGTVATLLAKAFCARVITTVGSEEKRQASLALGADVAINYRNEDFVEQTQRATNGKGADVIVDLIAGDYVAKNYQAAAMD
GRIVQIGTQNGVVKELNLMPLLIKRLTHTGSTLRARSVEDKAQIAADLRQKVWPLLERGALKPQIFKTFPLDQAAEAHAL
MESSQHIGKIMLTI

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=40.0602409638554, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=40.0602409638554, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI194239674, Length=328, Percent_Identity=30.1829268292683, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI13236495, Length=328, Percent_Identity=30.1829268292683, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=28.0487804878049, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=27.0096463022508, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI24308257, Length=326, Percent_Identity=26.0736196319018, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI41872631, Length=312, Percent_Identity=28.8461538461538, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI197927207, Length=190, Percent_Identity=30.5263157894737, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI28557745, Length=265, Percent_Identity=30.9433962264151, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI47519420, Length=363, Percent_Identity=26.1707988980716, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=30.8868501529052, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787863, Length=361, Percent_Identity=27.9778393351801, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507255, Length=328, Percent_Identity=25.9146341463415, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=308, Percent_Identity=28.8961038961039, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71987554, Length=175, Percent_Identity=33.1428571428571, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=335, Percent_Identity=28.955223880597, Blast_Score=125, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6323961, Length=332, Percent_Identity=26.5060240963855, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=332, Percent_Identity=26.5060240963855, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=363, Percent_Identity=25.068870523416, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319621, Length=331, Percent_Identity=24.773413897281, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920632, Length=302, Percent_Identity=27.1523178807947, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221330659, Length=302, Percent_Identity=27.1523178807947, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24581345, Length=346, Percent_Identity=26.5895953757225, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35565; Mature: 35434

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANPALPNTMKVVEISQPGEPEVLISSQRPLPTLQQGEILVKVAAAGVNRPDVMQRRGQ
CCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCC
YAPPAGASDIPGLEIAGTVVAIGIGVQNYAIGDAVCALIAGGGYAEYCKVHESNALPVPE
CCCCCCCCCCCCCEECCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHEECCCCCCCCC
GFSLIEAAAIPETFFTVWVNVFQRGHLKAGETVLIHGGTSGIGTVATLLAKAFCARVITT
CCHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VGSEEKRQASLALGADVAINYRNEDFVEQTQRATNGKGADVIVDLIAGDYVAKNYQAAAM
CCCHHHHHHHHEECCEEEEECCCHHHHHHHHHHCCCCCHHEEEEEHHCCHHHCCCEEEEC
DGRIVQIGTQNGVVKELNLMPLLIKRLTHTGSTLRARSVEDKAQIAADLRQKVWPLLERG
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHC
ALKPQIFKTFPLDQAAEAHALMESSQHIGKIMLTI
CCCCHHHEECCCCHHHHHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure 
SANPALPNTMKVVEISQPGEPEVLISSQRPLPTLQQGEILVKVAAAGVNRPDVMQRRGQ
CCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCC
YAPPAGASDIPGLEIAGTVVAIGIGVQNYAIGDAVCALIAGGGYAEYCKVHESNALPVPE
CCCCCCCCCCCCCEECCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHEECCCCCCCCC
GFSLIEAAAIPETFFTVWVNVFQRGHLKAGETVLIHGGTSGIGTVATLLAKAFCARVITT
CCHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VGSEEKRQASLALGADVAINYRNEDFVEQTQRATNGKGADVIVDLIAGDYVAKNYQAAAM
CCCHHHHHHHHEECCEEEEECCCHHHHHHHHHHCCCCCHHEEEEEHHCCHHHCCCEEEEC
DGRIVQIGTQNGVVKELNLMPLLIKRLTHTGSTLRARSVEDKAQIAADLRQKVWPLLERG
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHC
ALKPQIFKTFPLDQAAEAHALMESSQHIGKIMLTI
CCCCHHHEECCCCHHHHHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]