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The map label for this gene is lpfA [H]

Identifier: 157371118

GI number: 157371118

Start: 3157974

End: 3158501

Strand: Direct

Name: lpfA [H]

Synonym: Spro_2878

Alternate gene names: 157371118

Gene position: 3157974-3158501 (Clockwise)

Preceding gene: 157371117

Following gene: 157371119

Centisome position: 57.96

GC content: 56.82

Gene sequence:

>528_bases
ATGCACATGGTAGCTTTAAAGACTGCTCGGGCGCTACTGACGCTAATGCTTTGCAGTGGTGCTGTCTGGGCCGACGATGC
CAGTGTCAATATTACCGGACGCGTGCTGTCGGCAGCTTGTGAGCCGACGGTTGACCCGCTGGCAGTGGACTTGGGCACCC
TGTCGCGCAGCATATTAAGCAGCAAGGGCGTGACAGGTTCCCATACAGACTTCACATTGCGCCTAAAGAGCTGCCCGGCA
GAGGTCAGCCAGGTACAGGTTCAGTTTGATGGCGTCGCCGCAACCGGAGATAACAGTGCATTAGCCCTGACCGGCAGCAG
CGTGGCTAAAGGGGTCGGTGTGCAACTGCTGGACAATGCGAAAAAAGTGTTGGCACCGGGGACGCGCTCACCATTGATGT
CAATCATCGGGGGTAATAGCACCGTGAATTCTCTGGCCTTCAGCGCACGCTACATCGCCACCAGCGACACTGTGACCGCT
GGCAGTGCCAATGCCAGCGCCACCTTTACCATTTGGTACAACAATTGA

Upstream 100 bases:

>100_bases
AGATTTATTCGAAAGGCTCTGCCACCGCCGGCACGGTAATTGGCAATATCGTGGTGTCCTTTACCTATCAATAACTCATT
GCGACGACAAGGAATCTGTC

Downstream 100 bases:

>100_bases
AGCTCACGCCGGTTCATCCCTTTGCGGCATCGCGTTGCGCGCACGCTGGTCCGCAGCCCCTCCAGCACGACGGTGAGCCT
GCTCGCCAGGCTCTGCTGCC

Product: fimbrial protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MHMVALKTARALLTLMLCSGAVWADDASVNITGRVLSAACEPTVDPLAVDLGTLSRSILSSKGVTGSHTDFTLRLKSCPA
EVSQVQVQFDGVAATGDNSALALTGSSVAKGVGVQLLDNAKKVLAPGTRSPLMSIIGGNSTVNSLAFSARYIATSDTVTA
GSANASATFTIWYNN

Sequences:

>Translated_175_residues
MHMVALKTARALLTLMLCSGAVWADDASVNITGRVLSAACEPTVDPLAVDLGTLSRSILSSKGVTGSHTDFTLRLKSCPA
EVSQVQVQFDGVAATGDNSALALTGSSVAKGVGVQLLDNAKKVLAPGTRSPLMSIIGGNSTVNSLAFSARYIATSDTVTA
GSANASATFTIWYNN
>Mature_175_residues
MHMVALKTARALLTLMLCSGAVWADDASVNITGRVLSAACEPTVDPLAVDLGTLSRSILSSKGVTGSHTDFTLRLKSCPA
EVSQVQVQFDGVAATGDNSALALTGSSVAKGVGVQLLDNAKKVLAPGTRSPLMSIIGGNSTVNSLAFSARYIATSDTVTA
GSANASATFTIWYNN

Specific function: Fimbriae (Also Called Pili), Polar Filaments Radiating From The Surface Of The Bacterium To A Length Of 0.5-1.5 Micrometers And Numbering 100-300 Per Cell, Enable Bacteria To Colonize The Epithelium Of Specific Host Organs (By Similarity). [C]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI87081753, Length=163, Percent_Identity=33.1288343558282, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1787781, Length=165, Percent_Identity=31.5151515151515, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790773, Length=156, Percent_Identity=33.974358974359, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1786746, Length=166, Percent_Identity=33.1325301204819, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 17892; Mature: 17892

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMVALKTARALLTLMLCSGAVWADDASVNITGRVLSAACEPTVDPLAVDLGTLSRSILS
CCEEHHHHHHHHHHHHHHCCCEECCCCCEEEEHHEEECCCCCCCCCEEEHHHHHHHHHHH
SKGVTGSHTDFTLRLKSCPAEVSQVQVQFDGVAATGDNSALALTGSSVAKGVGVQLLDNA
CCCCCCCCCEEEEEEECCCCCCEEEEEEECCEEECCCCCEEEEECCHHHCCCCEEECCCC
KKVLAPGTRSPLMSIIGGNSTVNSLAFSARYIATSDTVTAGSANASATFTIWYNN
HHHCCCCCCCCHHHHHCCCCCHHHHHEEEEEEEECCCEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MHMVALKTARALLTLMLCSGAVWADDASVNITGRVLSAACEPTVDPLAVDLGTLSRSILS
CCEEHHHHHHHHHHHHHHCCCEECCCCCEEEEHHEEECCCCCCCCCEEEHHHHHHHHHHH
SKGVTGSHTDFTLRLKSCPAEVSQVQVQFDGVAATGDNSALALTGSSVAKGVGVQLLDNA
CCCCCCCCCEEEEEEECCCCCCEEEEEEECCEEECCCCCEEEEECCHHHCCCCEEECCCC
KKVLAPGTRSPLMSIIGGNSTVNSLAFSARYIATSDTVTAGSANASATFTIWYNN
HHHCCCCCCCCHHHHHCCCCCHHHHHEEEEEEEECCCEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721701; 11677609 [H]