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The map label for this gene is ubiB [C]

Identifier: 157371039

GI number: 157371039

Start: 3078381

End: 3080021

Strand: Direct

Name: ubiB [C]

Synonym: Spro_2799

Alternate gene names: 157371039

Gene position: 3078381-3080021 (Clockwise)

Preceding gene: 157371038

Following gene: 157371040

Centisome position: 56.5

GC content: 58.87

Gene sequence:

>1641_bases
ATGTTGAAAATGGTGCTGGTTACCGCCCGCGATCGGGCGAGGCTGAAAGAAATATCCGCGGTGCTGATCCGCTACGGCCT
GCAGGATGTCATTCGCCTGCTGGGCCTGAGCACCCTGCTAAGCGGCGGTGAAGGCGGCGGTGAACCGCAAGATAACCAAA
CCTTGCCACAACGCTTGCGTGCCGCACTGGAAGCGCTGGGGCCAACCTTTGTCAAATTCGGCCAGATCCTGGCTACCCGC
TCAGACCTGTTGGACTCAAGCTGGACCGACGAACTGGATCGCCTGCACAGCCAGGCGACAACCCTGGCCTGGAGCGAACT
GGCACCGCAGATTACCGCCGATTTGGGCGGTGACCCACACCACCTGTTCGCCGAGTTTGATCAAGCCCCACTGGCCGCCG
CATCGATGGCACAGATTTATCGTGCCCGTTTGCACAGCGGTGAAGCCGTGGTGATCAAGGTATTACGCCCTGGGCTGGCA
AAAACCATTCACGCCGATTTGCGCCTGCTGGCCTATCTGGCGGAAACCGTGGAACAACAAAGCCCGGCGCTGGCCCGCTA
CCGGCCGCGTCAGATGGTACGAGCGCTGGCAACCGCGCTTAATCATGAGCTGGACCTGACTCACGAAGGCAATAACTGTG
AACGGGTGGCTCAGCAATTTGCTCAACAGCCCGAGGTAGTAATACCGAAAATTTACTGGCAATGGTCGTCAAAACGTCTG
CTGGTGCAGGAGTTTCTGCCCGGCATCGCGCCGGAAAATCCACAGCAATTGGCAACCGCCGGTTTTGATGGCCCACTTCT
CGCACAGCGCGGCGCACAGGCCTTTATGAAAATGGTGCTGGAGCACCGGCTTTATCACGCCGATCCGCACCCGGGTAATC
TGATGGCGTTAGCGGATAATCGCGTCGGCTTTATCGATTTCGGTATGGTCGGCCAACTTTCCGAACGGCGGCGCAATCAG
TTACTGCTGTTGCTGCAGGCGATTGCCGAGCGGGAGTCCGGCGGTATCGTCAATACCTTGATCGCCTGGTCGGACAGCGA
TCCTTTGGATCTGCTGGATTTGGAACTGGCGGCGCAAAACTTTCTCGATAAGCAGGCTTCGGCAACCCTGACGCTGGGTA
AGGCATTGACCGATCTGCTGGTGATGGCGCGTGAACATCAGTTGGCGCTGCCACCGGATCTGGTGTTGCTGTTCAAGGCG
TTAATCACCGCAGACGGCGTGTTGCACCGGTTGGATCCCAATTTCGACATCATCGCCACCCTGAAACCCATGCTGCAACA
GGTGATGCTGCAGCGTTACACCCCTGAAGCGGTGCGTCGGCGGATGCTGGCGCTAGGTGGTGAAGCGCTGGATGCGGGCG
AAGAACTTCCGCAGACCCTGCGTCTGCTGATGCGCCGACTAAAACGCGGGCAAATCAGCGCCGATATCAACCTCAAGAAC
ATCAGTCAGTTAAGCAAGGCGCTGGAACGTGCTGCCGTCACGCTGGCCATTGCCATAGTGACCGCCGCCTTCACGCTGGG
TCTGGCGCCCTATCTGATGCAATCCTCGGTGCGGTTGTGGGGCATTCCGCTGTTTCCGGCACTGGGCGGGTTAGCCTGTC
TGGGGGGAGTACTGTTGCTGGTATTGCGTTTGCGGCGCTGA

Upstream 100 bases:

>100_bases
AACATCGAAGCCTATCGTAACCGGATGGCGCAGCGCAGTGATATTCCACTGCTGTTCGATATGGAACAGTGATCCCCCGC
AATAAGGATATAGCGCGCAA

Downstream 100 bases:

>100_bases
ACAGTTTCGGCGTTATCCGATAGGTCATGACAAGTTTTCCGCGCATTATCAATATTATCCCATGTTCTGGAAGGGTCGCG
GTATACTGCGGCCATGTCAA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MLKMVLVTARDRARLKEISAVLIRYGLQDVIRLLGLSTLLSGGEGGGEPQDNQTLPQRLRAALEALGPTFVKFGQILATR
SDLLDSSWTDELDRLHSQATTLAWSELAPQITADLGGDPHHLFAEFDQAPLAAASMAQIYRARLHSGEAVVIKVLRPGLA
KTIHADLRLLAYLAETVEQQSPALARYRPRQMVRALATALNHELDLTHEGNNCERVAQQFAQQPEVVIPKIYWQWSSKRL
LVQEFLPGIAPENPQQLATAGFDGPLLAQRGAQAFMKMVLEHRLYHADPHPGNLMALADNRVGFIDFGMVGQLSERRRNQ
LLLLLQAIAERESGGIVNTLIAWSDSDPLDLLDLELAAQNFLDKQASATLTLGKALTDLLVMAREHQLALPPDLVLLFKA
LITADGVLHRLDPNFDIIATLKPMLQQVMLQRYTPEAVRRRMLALGGEALDAGEELPQTLRLLMRRLKRGQISADINLKN
ISQLSKALERAAVTLAIAIVTAAFTLGLAPYLMQSSVRLWGIPLFPALGGLACLGGVLLLVLRLRR

Sequences:

>Translated_546_residues
MLKMVLVTARDRARLKEISAVLIRYGLQDVIRLLGLSTLLSGGEGGGEPQDNQTLPQRLRAALEALGPTFVKFGQILATR
SDLLDSSWTDELDRLHSQATTLAWSELAPQITADLGGDPHHLFAEFDQAPLAAASMAQIYRARLHSGEAVVIKVLRPGLA
KTIHADLRLLAYLAETVEQQSPALARYRPRQMVRALATALNHELDLTHEGNNCERVAQQFAQQPEVVIPKIYWQWSSKRL
LVQEFLPGIAPENPQQLATAGFDGPLLAQRGAQAFMKMVLEHRLYHADPHPGNLMALADNRVGFIDFGMVGQLSERRRNQ
LLLLLQAIAERESGGIVNTLIAWSDSDPLDLLDLELAAQNFLDKQASATLTLGKALTDLLVMAREHQLALPPDLVLLFKA
LITADGVLHRLDPNFDIIATLKPMLQQVMLQRYTPEAVRRRMLALGGEALDAGEELPQTLRLLMRRLKRGQISADINLKN
ISQLSKALERAAVTLAIAIVTAAFTLGLAPYLMQSSVRLWGIPLFPALGGLACLGGVLLLVLRLRR
>Mature_546_residues
MLKMVLVTARDRARLKEISAVLIRYGLQDVIRLLGLSTLLSGGEGGGEPQDNQTLPQRLRAALEALGPTFVKFGQILATR
SDLLDSSWTDELDRLHSQATTLAWSELAPQITADLGGDPHHLFAEFDQAPLAAASMAQIYRARLHSGEAVVIKVLRPGLA
KTIHADLRLLAYLAETVEQQSPALARYRPRQMVRALATALNHELDLTHEGNNCERVAQQFAQQPEVVIPKIYWQWSSKRL
LVQEFLPGIAPENPQQLATAGFDGPLLAQRGAQAFMKMVLEHRLYHADPHPGNLMALADNRVGFIDFGMVGQLSERRRNQ
LLLLLQAIAERESGGIVNTLIAWSDSDPLDLLDLELAAQNFLDKQASATLTLGKALTDLLVMAREHQLALPPDLVLLFKA
LITADGVLHRLDPNFDIIATLKPMLQQVMLQRYTPEAVRRRMLALGGEALDAGEELPQTLRLLMRRLKRGQISADINLKN
ISQLSKALERAAVTLAIAIVTAAFTLGLAPYLMQSSVRLWGIPLFPALGGLACLGGVLLLVLRLRR

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=347, Percent_Identity=29.3948126801153, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI40254938, Length=265, Percent_Identity=30.9433962264151, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI217035081, Length=214, Percent_Identity=28.9719626168224, Blast_Score=103, Evalue=6e-22,
Organism=Escherichia coli, GI2367309, Length=438, Percent_Identity=32.1917808219178, Blast_Score=197, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17559152, Length=258, Percent_Identity=27.5193798449612, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6325148, Length=436, Percent_Identity=25, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323282, Length=262, Percent_Identity=26.7175572519084, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321319, Length=314, Percent_Identity=23.2484076433121, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI22024280, Length=258, Percent_Identity=31.0077519379845, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24662575, Length=273, Percent_Identity=27.8388278388278, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI18859849, Length=245, Percent_Identity=25.3061224489796, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 60117; Mature: 60117

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKMVLVTARDRARLKEISAVLIRYGLQDVIRLLGLSTLLSGGEGGGEPQDNQTLPQRLR
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
AALEALGPTFVKFGQILATRSDLLDSSWTDELDRLHSQATTLAWSELAPQITADLGGDPH
HHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
HLFAEFDQAPLAAASMAQIYRARLHSGEAVVIKVLRPGLAKTIHADLRLLAYLAETVEQQ
HHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHC
SPALARYRPRQMVRALATALNHELDLTHEGNNCERVAQQFAQQPEVVIPKIYWQWSSKRL
CCHHHHCCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCEEECHHEEEECCCCH
LVQEFLPGIAPENPQQLATAGFDGPLLAQRGAQAFMKMVLEHRLYHADPHPGNLMALADN
HHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
RVGFIDFGMVGQLSERRRNQLLLLLQAIAERESGGIVNTLIAWSDSDPLDLLDLELAAQN
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHH
FLDKQASATLTLGKALTDLLVMAREHQLALPPDLVLLFKALITADGVLHRLDPNFDIIAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHH
LKPMLQQVMLQRYTPEAVRRRMLALGGEALDAGEELPQTLRLLMRRLKRGQISADINLKN
HHHHHHHHHHHHCCHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ISQLSKALERAAVTLAIAIVTAAFTLGLAPYLMQSSVRLWGIPLFPALGGLACLGGVLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHH
VLRLRR
HHHHCC
>Mature Secondary Structure
MLKMVLVTARDRARLKEISAVLIRYGLQDVIRLLGLSTLLSGGEGGGEPQDNQTLPQRLR
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
AALEALGPTFVKFGQILATRSDLLDSSWTDELDRLHSQATTLAWSELAPQITADLGGDPH
HHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
HLFAEFDQAPLAAASMAQIYRARLHSGEAVVIKVLRPGLAKTIHADLRLLAYLAETVEQQ
HHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHC
SPALARYRPRQMVRALATALNHELDLTHEGNNCERVAQQFAQQPEVVIPKIYWQWSSKRL
CCHHHHCCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCEEECHHEEEECCCCH
LVQEFLPGIAPENPQQLATAGFDGPLLAQRGAQAFMKMVLEHRLYHADPHPGNLMALADN
HHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
RVGFIDFGMVGQLSERRRNQLLLLLQAIAERESGGIVNTLIAWSDSDPLDLLDLELAAQN
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHH
FLDKQASATLTLGKALTDLLVMAREHQLALPPDLVLLFKALITADGVLHRLDPNFDIIAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHH
LKPMLQQVMLQRYTPEAVRRRMLALGGEALDAGEELPQTLRLLMRRLKRGQISADINLKN
HHHHHHHHHHHHCCHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ISQLSKALERAAVTLAIAIVTAAFTLGLAPYLMQSSVRLWGIPLFPALGGLACLGGVLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHH
VLRLRR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]