Click here to switch to the map view.

The map label for this gene is cutC

Identifier: 157371028

GI number: 157371028

Start: 3066605

End: 3067363

Strand: Reverse

Name: cutC

Synonym: Spro_2788

Alternate gene names: 157371028

Gene position: 3067363-3066605 (Counterclockwise)

Preceding gene: 157371030

Following gene: 157371022

Centisome position: 56.29

GC content: 55.2

Gene sequence:

>759_bases
ATGATAAAACTGGAAGTTTGTTGCTATAGCGTCGATTGCGCGCTGACGGCTGAGCGGGCAGGTGCCGATCGCATAGAATT
GTGCGCCAGCCCGAGTGAGGGCGGTTTGACACCCAGCTACGGCTCATTACGCCTGGCGCGCGACAGGGTCAGCGTGCCGG
TGCATCCTATTATTCGTCCGCGCGGTGGGGATTTTTGCTACGGTGCGGTGGATTTTGATGTGATCAAGCATGATATTGCA
CAGATCCGCGATATGGGTTTTGCCGGTGTGGTGGTCGGCATGCTGGATGAAGAAGGGCATATCGACCTGCAACGCATGCG
TGAAGTGATGCGCTTGAGTGGCAATATGGCGGTGACCTTTCATCGCGCGTTTGATATGTGTCAGAACCCGATGGTCGCGC
TCAGTCAACTAACTCAGTTGGGCGTGGCGCGGATACTGACTTCCGGCCAGCAGCAAAATGCGGAGCTGGGTTTACCCTTG
CTGCGTGATCTGCTGCAGGCCAGTCAGGGGCCGGTAATTATGGCCGGTGCCGGCGTGCGCCTGAGCAATCTGCATAAATT
TGTCGATATAGGTATTCAGGAGCTGCATAGCTCATCCGGTCATGCGGTGCCTTCGACCATGCGTTATCGCAAAGCCGGCG
TGACCATGTGTTCAGACAGTGAGTTTGATGAATTTAGCCATTATTGCGTGGACGGCGAAATGGTCGAAGCCATGAAAAAC
TCGTTGGCGCTGGTCGATCCGCTGGTGCAAAGTGCCTAA

Upstream 100 bases:

>100_bases
GTTACTACCCTGTATAGGTTGATAGCTCTTTATCAGCCTAAGAGATAAATCGAAAAATTAACAATTGCCGTCGCAGGTTA
GCCGTCATCTGGGGGTGACA

Downstream 100 bases:

>100_bases
AGCACGTGGCCAAAGCATTTACCGACTGACAACATCATCCCCGTTGAATGTAAATCCAGCGGGGATGATGTTTTGGGCCT
TAAGGTTTCCGGGCCACCAG

Product: copper homeostasis protein CutC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MIKLEVCCYSVDCALTAERAGADRIELCASPSEGGLTPSYGSLRLARDRVSVPVHPIIRPRGGDFCYGAVDFDVIKHDIA
QIRDMGFAGVVVGMLDEEGHIDLQRMREVMRLSGNMAVTFHRAFDMCQNPMVALSQLTQLGVARILTSGQQQNAELGLPL
LRDLLQASQGPVIMAGAGVRLSNLHKFVDIGIQELHSSSGHAVPSTMRYRKAGVTMCSDSEFDEFSHYCVDGEMVEAMKN
SLALVDPLVQSA

Sequences:

>Translated_252_residues
MIKLEVCCYSVDCALTAERAGADRIELCASPSEGGLTPSYGSLRLARDRVSVPVHPIIRPRGGDFCYGAVDFDVIKHDIA
QIRDMGFAGVVVGMLDEEGHIDLQRMREVMRLSGNMAVTFHRAFDMCQNPMVALSQLTQLGVARILTSGQQQNAELGLPL
LRDLLQASQGPVIMAGAGVRLSNLHKFVDIGIQELHSSSGHAVPSTMRYRKAGVTMCSDSEFDEFSHYCVDGEMVEAMKN
SLALVDPLVQSA
>Mature_252_residues
MIKLEVCCYSVDCALTAERAGADRIELCASPSEGGLTPSYGSLRLARDRVSVPVHPIIRPRGGDFCYGAVDFDVIKHDIA
QIRDMGFAGVVVGMLDEEGHIDLQRMREVMRLSGNMAVTFHRAFDMCQNPMVALSQLTQLGVARILTSGQQQNAELGLPL
LRDLLQASQGPVIMAGAGVRLSNLHKFVDIGIQELHSSSGHAVPSTMRYRKAGVTMCSDSEFDEFSHYCVDGEMVEAMKN
SLALVDPLVQSA

Specific function: Involved in copper homeostasis

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family

Homologues:

Organism=Homo sapiens, GI148596990, Length=242, Percent_Identity=42.1487603305785, Blast_Score=181, Evalue=6e-46,
Organism=Escherichia coli, GI87081995, Length=239, Percent_Identity=55.2301255230126, Blast_Score=289, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17556905, Length=190, Percent_Identity=32.6315789473684, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21355415, Length=226, Percent_Identity=36.283185840708, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CUTC_SERP5 (A8GFJ9)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479017.1
- ProteinModelPortal:   A8GFJ9
- SMR:   A8GFJ9
- STRING:   A8GFJ9
- GeneID:   5603189
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2788
- eggNOG:   COG3142
- HOGENOM:   HBG535337
- OMA:   PVYAMIR
- ProtClustDB:   PRK11572
- BioCyc:   SPRO399741:SPRO_2788-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00795
- InterPro:   IPR005627
- Gene3D:   G3DSA:3.20.20.380
- PANTHER:   PTHR12598

Pfam domain/function: PF03932 CutC; SSF110395 CutC

EC number: NA

Molecular weight: Translated: 27385; Mature: 27385

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLEVCCYSVDCALTAERAGADRIELCASPSEGGLTPSYGSLRLARDRVSVPVHPIIRP
CEEEEEEEEEECCEEEHHHCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCEECC
RGGDFCYGAVDFDVIKHDIAQIRDMGFAGVVVGMLDEEGHIDLQRMREVMRLSGNMAVTF
CCCCEEEECHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCHHHHHHHHHHCCCEEEEE
HRAFDMCQNPMVALSQLTQLGVARILTSGQQQNAELGLPLLRDLLQASQGPVIMAGAGVR
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCC
LSNLHKFVDIGIQELHSSSGHAVPSTMRYRKAGVTMCSDSEFDEFSHYCVDGEMVEAMKN
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCHHHHHHHCCCHHHHHHHHH
SLALVDPLVQSA
HHHHHHHHHHCC
>Mature Secondary Structure
MIKLEVCCYSVDCALTAERAGADRIELCASPSEGGLTPSYGSLRLARDRVSVPVHPIIRP
CEEEEEEEEEECCEEEHHHCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCEECC
RGGDFCYGAVDFDVIKHDIAQIRDMGFAGVVVGMLDEEGHIDLQRMREVMRLSGNMAVTF
CCCCEEEECHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCHHHHHHHHHHCCCEEEEE
HRAFDMCQNPMVALSQLTQLGVARILTSGQQQNAELGLPLLRDLLQASQGPVIMAGAGVR
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCC
LSNLHKFVDIGIQELHSSSGHAVPSTMRYRKAGVTMCSDSEFDEFSHYCVDGEMVEAMKN
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCHHHHHHHCCCHHHHHHHHH
SLALVDPLVQSA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA