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The map label for this gene is msbB1 [H]

Identifier: 157371011

GI number: 157371011

Start: 3051648

End: 3052616

Strand: Reverse

Name: msbB1 [H]

Synonym: Spro_2771

Alternate gene names: 157371011

Gene position: 3052616-3051648 (Counterclockwise)

Preceding gene: 157371012

Following gene: 157371008

Centisome position: 56.02

GC content: 55.11

Gene sequence:

>969_bases
ATGCAAAACGAAAAAAAATCTAACTCAGAGTTCATCCCGCAATTTCAGAAAGCCTTTTACCACCCGCGCTACTGGGGCGT
TTGGCTGGGAACCGGGCTGATGGCCGGTATTTCATTAGTGCCTGCGCGCTTGCGCGATCCGGTGCTGGGTGCCGTTGGCA
AGCTGGCCGGCAAGGTGGCTAAAGGTGCCCGACGTCGTGCGCGCATCAACCTGCTGTATTGTTTGCCGGAAGTGCCGGAA
AACGAGCGTGAGCACATCATTGATGAGATGTTTGCCACCGCGCCGCAGTCGATGATCCTGATGGCCGAACTGGCCTGTAC
CAAACCGGAAAAAGTGTTGAAGCGCGTTCGCTGGCACGGGGAAGAGGTGCTGGATAAAATCCGTGAAGAAGGCCGTAACG
TGATTTTTCTGGTACCACATGGCTGGGCGGTGGATGTTCCGGCGATGTTAATGGCGGCTCGCGGTCAGCCGATGGCGGCG
ATGTTCCACAACCAGAGCAACCCGTTGGTCGACTACCTGTGGAATACGGTGCGCCGTAAATTTGGTGGACGGATGCATGC
GCGCAATGACGGCATCAAGCCTTTTATCAGCTCAGTGCGCCAGGGCTATTGGGGTTATTATCTGCCCGATCAGGATCACG
GTGCCGAACACAGTGAGTTCGTCGACTTCTTCGCCACCTATAAGGCGACGCTGCCGGCAGTGGGCCGTCTGATGAAAGTC
TGCCGTGCGGCCATTGTGCCTTTGTTCCCGGTGTATGACGGCAAAACCAGTATGCTGGATGTTTATATTCGTCCGCCGAT
GGACGATTTGGCCACCGCCGATGACCACACTATTGCGCGTCGGATGAATGAAGAGGTCGAGAATCTGGTAGGGCCGAACC
CGGAACAGTACACCTGGATCCTCAAACTGTTGAAAACGCGTAAAGAAGGTGAGATTGAACCTTATTCGCGCGATGATCTC
TATCGCTAA

Upstream 100 bases:

>100_bases
TCGGGCCGATGTTGTTTTATATTGGCGCTTCGCCGTGGTTAATTGCAAAATCAATCTTTGCAATTATGATTAGCCGAACC
GCTAAGTTAAGAGCTTGTGC

Downstream 100 bases:

>100_bases
AAGTCATATTTGCTTAATGCCAAAGGTCAGTCATCTCAGGTGATTGGCCTTTTTCGTATGGTGCTTAAAAATGCAATAGG
TGGCTCTCCATTTGCCGTAA

Product: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MQNEKKSNSEFIPQFQKAFYHPRYWGVWLGTGLMAGISLVPARLRDPVLGAVGKLAGKVAKGARRRARINLLYCLPEVPE
NEREHIIDEMFATAPQSMILMAELACTKPEKVLKRVRWHGEEVLDKIREEGRNVIFLVPHGWAVDVPAMLMAARGQPMAA
MFHNQSNPLVDYLWNTVRRKFGGRMHARNDGIKPFISSVRQGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAVGRLMKV
CRAAIVPLFPVYDGKTSMLDVYIRPPMDDLATADDHTIARRMNEEVENLVGPNPEQYTWILKLLKTRKEGEIEPYSRDDL
YR

Sequences:

>Translated_322_residues
MQNEKKSNSEFIPQFQKAFYHPRYWGVWLGTGLMAGISLVPARLRDPVLGAVGKLAGKVAKGARRRARINLLYCLPEVPE
NEREHIIDEMFATAPQSMILMAELACTKPEKVLKRVRWHGEEVLDKIREEGRNVIFLVPHGWAVDVPAMLMAARGQPMAA
MFHNQSNPLVDYLWNTVRRKFGGRMHARNDGIKPFISSVRQGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAVGRLMKV
CRAAIVPLFPVYDGKTSMLDVYIRPPMDDLATADDHTIARRMNEEVENLVGPNPEQYTWILKLLKTRKEGEIEPYSRDDL
YR
>Mature_322_residues
MQNEKKSNSEFIPQFQKAFYHPRYWGVWLGTGLMAGISLVPARLRDPVLGAVGKLAGKVAKGARRRARINLLYCLPEVPE
NEREHIIDEMFATAPQSMILMAELACTKPEKVLKRVRWHGEEVLDKIREEGRNVIFLVPHGWAVDVPAMLMAARGQPMAA
MFHNQSNPLVDYLWNTVRRKFGGRMHARNDGIKPFISSVRQGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAVGRLMKV
CRAAIVPLFPVYDGKTSMLDVYIRPPMDDLATADDHTIARRMNEEVENLVGPNPEQYTWILKLLKTRKEGEIEPYSRDDL
YR

Specific function: Transfers myristate or laurate, activated on ACP, to (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1788161, Length=317, Percent_Identity=72.2397476340694, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI1787292, Length=312, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87082094, Length=310, Percent_Identity=28.7096774193548, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011921 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 36887; Mature: 36887

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNEKKSNSEFIPQFQKAFYHPRYWGVWLGTGLMAGISLVPARLRDPVLGAVGKLAGKVA
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
KGARRRARINLLYCLPEVPENEREHIIDEMFATAPQSMILMAELACTKPEKVLKRVRWHG
HHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCC
EEVLDKIREEGRNVIFLVPHGWAVDVPAMLMAARGQPMAAMFHNQSNPLVDYLWNTVRRK
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHH
FGGRMHARNDGIKPFISSVRQGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAVGRLMKV
HCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CRAAIVPLFPVYDGKTSMLDVYIRPPMDDLATADDHTIARRMNEEVENLVGPNPEQYTWI
HHHHHHHHCCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
LKLLKTRKEGEIEPYSRDDLYR
HHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQNEKKSNSEFIPQFQKAFYHPRYWGVWLGTGLMAGISLVPARLRDPVLGAVGKLAGKVA
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
KGARRRARINLLYCLPEVPENEREHIIDEMFATAPQSMILMAELACTKPEKVLKRVRWHG
HHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCC
EEVLDKIREEGRNVIFLVPHGWAVDVPAMLMAARGQPMAAMFHNQSNPLVDYLWNTVRRK
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHH
FGGRMHARNDGIKPFISSVRQGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAVGRLMKV
HCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CRAAIVPLFPVYDGKTSMLDVYIRPPMDDLATADDHTIARRMNEEVENLVGPNPEQYTWI
HHHHHHHHCCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
LKLLKTRKEGEIEPYSRDDLYR
HHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]