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The map label for this gene is pyrF [H]

Identifier: 157370887

GI number: 157370887

Start: 2915696

End: 2916451

Strand: Reverse

Name: pyrF [H]

Synonym: Spro_2647

Alternate gene names: 157370887

Gene position: 2916451-2915696 (Counterclockwise)

Preceding gene: 157370890

Following gene: 157370886

Centisome position: 53.52

GC content: 56.75

Gene sequence:

>756_bases
ATGTCCATTTTACAGAAGGTAGAAGAAATGAAGTCTGAAAATAACATTAATAACAATGACTTAAAATCATCTCCGATCAT
TGTTGCGCTTGATTACGCAGATATTGGCGCAGCATTGGCATTTGCCGATCGTATCAGTCCGCAGGACTGCCGGCTAAAAG
TGGGCAAGGAAATGTTCACCCTGTTTGGACCACAATTGGTGCGCGACTTGCACGCCCGCGGTTTCGATGTATTTCTGGAT
TTGAAATTTCACGATATTCCCAACACCACCGCCCGTGCGGTAGCGGCGGCGGCTGAACTGGGCGTGTGGATGGTTAACGT
TCACGCCAGCGGCGGTGCGCGGATGATGACCGCAGCCAAAGAGGCGTTGCTGCCTTATGGCGCGCAGGCGCCGTTGTTGA
TTGCCGTGACCGTGCTTACCAGCATGGAGGCGGAGGATTTGCAGGCTATCGGTATCGACCTCTCTCCGGCCGAACAGGCG
GAACGACTGGCGCGTCTGACCCGCGATTGTGGACTGGACGGCGTAGTCTGTTCTGCGCATGAGGCCGAACGCCTGAAAGC
GGCCTGTGGCCAGCAGTTCCAGTTGGTGACACCAGGTATCCGTCCGGAAGGCAGCGATGCCGGCGATCAGCGCCGTATTA
TGACGCCGGTGCAGGCACAGGCGGCCGGTGTTGACTATATGGTGATTGGGCGCCCGATCACCCAATCTGCCGATCCTGCC
GCTACGCTGAGCGCCATTCGCGCTTCACTGGCCTGA

Upstream 100 bases:

>100_bases
TGGGCCTAACATTACTTAACCGCAGGGTGCGCTGCGGCTGGGATTTCTGTCGGCTGGCATGTAGAATGCGGCGGTCAGTT
TGGCGGGTTGTTACCTGGTT

Downstream 100 bases:

>100_bases
GGAGTTACTGATGAAGGACGATAATAGCCGTCTGGTTTACTCCACCGACAGCGGACGCATCAAGCCGGAAGAGGTTAAGC
CACAGCGTGACAAGGGTGAC

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSILQKVEEMKSENNINNNDLKSSPIIVALDYADIGAALAFADRISPQDCRLKVGKEMFTLFGPQLVRDLHARGFDVFLD
LKFHDIPNTTARAVAAAAELGVWMVNVHASGGARMMTAAKEALLPYGAQAPLLIAVTVLTSMEAEDLQAIGIDLSPAEQA
ERLARLTRDCGLDGVVCSAHEAERLKAACGQQFQLVTPGIRPEGSDAGDQRRIMTPVQAQAAGVDYMVIGRPITQSADPA
ATLSAIRASLA

Sequences:

>Translated_251_residues
MSILQKVEEMKSENNINNNDLKSSPIIVALDYADIGAALAFADRISPQDCRLKVGKEMFTLFGPQLVRDLHARGFDVFLD
LKFHDIPNTTARAVAAAAELGVWMVNVHASGGARMMTAAKEALLPYGAQAPLLIAVTVLTSMEAEDLQAIGIDLSPAEQA
ERLARLTRDCGLDGVVCSAHEAERLKAACGQQFQLVTPGIRPEGSDAGDQRRIMTPVQAQAAGVDYMVIGRPITQSADPA
ATLSAIRASLA
>Mature_250_residues
SILQKVEEMKSENNINNNDLKSSPIIVALDYADIGAALAFADRISPQDCRLKVGKEMFTLFGPQLVRDLHARGFDVFLDL
KFHDIPNTTARAVAAAAELGVWMVNVHASGGARMMTAAKEALLPYGAQAPLLIAVTVLTSMEAEDLQAIGIDLSPAEQAE
RLARLTRDCGLDGVVCSAHEAERLKAACGQQFQLVTPGIRPEGSDAGDQRRIMTPVQAQAAGVDYMVIGRPITQSADPAA
TLSAIRASLA

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=230, Percent_Identity=75.6521739130435, Blast_Score=351, Evalue=3e-98,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 26768; Mature: 26637

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILQKVEEMKSENNINNNDLKSSPIIVALDYADIGAALAFADRISPQDCRLKVGKEMFT
CHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LFGPQLVRDLHARGFDVFLDLKFHDIPNTTARAVAAAAELGVWMVNVHASGGARMMTAAK
HHCHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHH
EALLPYGAQAPLLIAVTVLTSMEAEDLQAIGIDLSPAEQAERLARLTRDCGLDGVVCSAH
HHHCCCCCCCHHHHHHHHHHHCCHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCEEECCH
EAERLKAACGQQFQLVTPGIRPEGSDAGDQRRIMTPVQAQAAGVDYMVIGRPITQSADPA
HHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCCCCHH
ATLSAIRASLA
HHHHHHHHHCC
>Mature Secondary Structure 
SILQKVEEMKSENNINNNDLKSSPIIVALDYADIGAALAFADRISPQDCRLKVGKEMFT
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LFGPQLVRDLHARGFDVFLDLKFHDIPNTTARAVAAAAELGVWMVNVHASGGARMMTAAK
HHCHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHH
EALLPYGAQAPLLIAVTVLTSMEAEDLQAIGIDLSPAEQAERLARLTRDCGLDGVVCSAH
HHHCCCCCCCHHHHHHHHHHHCCHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCEEECCH
EAERLKAACGQQFQLVTPGIRPEGSDAGDQRRIMTPVQAQAAGVDYMVIGRPITQSADPA
HHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCCCCHH
ATLSAIRASLA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA