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The map label for this gene is ycgR

Identifier: 157370807

GI number: 157370807

Start: 2821650

End: 2822363

Strand: Reverse

Name: ycgR

Synonym: Spro_2567

Alternate gene names: 157370807

Gene position: 2822363-2821650 (Counterclockwise)

Preceding gene: 157370808

Following gene: 157370803

Centisome position: 51.8

GC content: 51.12

Gene sequence:

>714_bases
GTGGAGCAGAATGATAACGGATTGTTTATCAAGCAGGAGCGATTCGAAGTACTGGCAATACTGCGTGAAATTTGTAAACA
GCGCACGCCACTGAAGGTCGTCAATGATCGGCAGCAGTTTCAAAGCCTGCTGTTGAGCGTCGGGCCGGATAATATTGTGT
TTAGCGGCGATGAGGCGGACAACAGGGTCGACGGCGAATGCACCATTGTGATTGAAAGCCATGACGCGAAGATCGAATTT
TCCGTGGGACAGGCCGAGTTCACCGACCATCAAGGGGTTAACGCCTGTTCAACCCGATTGCCGAAAGAACTGATCTACAT
CCAGCGCCGTCGTCAGTTTCGCGTCACCACTCCCCACTGGCGTGAATTTCTCTGCAGCGGCGAATACGCCGATGGCAGCG
AGTACCAGTTGAGGATCCACGACCTGTCTGCCGGTGGCGTTGGTTTGCGAGTTGATGGCCCATTGCCGGAAAACCTGCAG
CCCGGCTTTCAGTTTAAAAAGGCCTTGTTGGATCTCGGCAGTTACGGCAGTTTCAAGGTCAATATGGAACTGGTGGTGAT
CAATGAAGATCACGAACTCGATGACGACGACAACATGGTGCACTTCTCGCGCCTGTCGTGCCGTTTTATGAAGCTGGGCC
TGGCAATGGAAAGAAAAATTCAGAGCGCAGTGTTTGCTTTCGAATTGGATTTCAATAAAAAGAAAAAACGCTAA

Upstream 100 bases:

>100_bases
AGGCCTGGCATCGCTGGCAAATTTGACTTTAGGAATATTCCCAGTGATGATAACTGTAAGGAACGTGTAAAGCGTCATTG
GGAAGAGTCAGGAGCGACGA

Downstream 100 bases:

>100_bases
ATAGGAAATCAGCGGGGCAGCAGGCTGCCCCGTCACTCCGTTCTATTCTATTTCAAGGCACGCAGGCTGCCGATTTCCTC
CAAACCGAAATGCGCCGCTT

Product: YcgR family protein

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MEQNDNGLFIKQERFEVLAILREICKQRTPLKVVNDRQQFQSLLLSVGPDNIVFSGDEADNRVDGECTIVIESHDAKIEF
SVGQAEFTDHQGVNACSTRLPKELIYIQRRRQFRVTTPHWREFLCSGEYADGSEYQLRIHDLSAGGVGLRVDGPLPENLQ
PGFQFKKALLDLGSYGSFKVNMELVVINEDHELDDDDNMVHFSRLSCRFMKLGLAMERKIQSAVFAFELDFNKKKKR

Sequences:

>Translated_237_residues
MEQNDNGLFIKQERFEVLAILREICKQRTPLKVVNDRQQFQSLLLSVGPDNIVFSGDEADNRVDGECTIVIESHDAKIEF
SVGQAEFTDHQGVNACSTRLPKELIYIQRRRQFRVTTPHWREFLCSGEYADGSEYQLRIHDLSAGGVGLRVDGPLPENLQ
PGFQFKKALLDLGSYGSFKVNMELVVINEDHELDDDDNMVHFSRLSCRFMKLGLAMERKIQSAVFAFELDFNKKKKR
>Mature_237_residues
MEQNDNGLFIKQERFEVLAILREICKQRTPLKVVNDRQQFQSLLLSVGPDNIVFSGDEADNRVDGECTIVIESHDAKIEF
SVGQAEFTDHQGVNACSTRLPKELIYIQRRRQFRVTTPHWREFLCSGEYADGSEYQLRIHDLSAGGVGLRVDGPLPENLQ
PGFQFKKALLDLGSYGSFKVNMELVVINEDHELDDDDNMVHFSRLSCRFMKLGLAMERKIQSAVFAFELDFNKKKKR

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain

Homologues:

Organism=Escherichia coli, GI1787443, Length=231, Percent_Identity=31.6017316017316, Blast_Score=137, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCGR_SERP5 (A8GEX8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478796.1
- ProteinModelPortal:   A8GEX8
- SMR:   A8GEX8
- STRING:   A8GEX8
- GeneID:   5604471
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2567
- eggNOG:   COG5581
- OMA:   AGLHEGM
- BioCyc:   SPRO399741:SPRO_2567-MONOMER
- HAMAP:   MF_01457
- InterPro:   IPR009875
- InterPro:   IPR009926

Pfam domain/function: PF07238 PilZ; PF07317 YcgR

EC number: NA

Molecular weight: Translated: 27189; Mature: 27189

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNDNGLFIKQERFEVLAILREICKQRTPLKVVNDRQQFQSLLLSVGPDNIVFSGDEAD
CCCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCEEECCCCCC
NRVDGECTIVIESHDAKIEFSVGQAEFTDHQGVNACSTRLPKELIYIQRRRQFRVTTPHW
CCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHCCHHHHHHHHCCEEECCCHHH
REFLCSGEYADGSEYQLRIHDLSAGGVGLRVDGPLPENLQPGFQFKKALLDLGSYGSFKV
HHHHHCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEE
NMELVVINEDHELDDDDNMVHFSRLSCRFMKLGLAMERKIQSAVFAFELDFNKKKKR
EEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCC
>Mature Secondary Structure
MEQNDNGLFIKQERFEVLAILREICKQRTPLKVVNDRQQFQSLLLSVGPDNIVFSGDEAD
CCCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCEEECCCCCC
NRVDGECTIVIESHDAKIEFSVGQAEFTDHQGVNACSTRLPKELIYIQRRRQFRVTTPHW
CCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHCCHHHHHHHHCCEEECCCHHH
REFLCSGEYADGSEYQLRIHDLSAGGVGLRVDGPLPENLQPGFQFKKALLDLGSYGSFKV
HHHHHCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEE
NMELVVINEDHELDDDDNMVHFSRLSCRFMKLGLAMERKIQSAVFAFELDFNKKKKR
EEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA