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The map label for this gene is acoR [H]

Identifier: 157370651

GI number: 157370651

Start: 2634438

End: 2636225

Strand: Direct

Name: acoR [H]

Synonym: Spro_2411

Alternate gene names: 157370651

Gene position: 2634438-2636225 (Clockwise)

Preceding gene: 157370643

Following gene: 157370656

Centisome position: 48.35

GC content: 58.0

Gene sequence:

>1788_bases
ATGTTGCAGAAAGACCAGACCGGGTTTGTCTCTGATAGCGATAACCTGTCTCTCCCTGGCCCCTTGTCGGAATCATGGCT
GCGCAGTCGGCATTACGGCCTTGATCGGACCGACGATCTTGTCCCTTTTGTTCGGCCTGCGTTGCTCAACGAAGTCCGTG
GGCAAAACGGCTGGGTGGCGCAACTGGCGCGGCCGTTGATCGAACGCCTGGGCGGCGAAATTAACCGGCAACCCTCAATA
GTGGTGGTCTCTGATGCCAAGGGTCTGGTGCTGGAAACCTGTGGCAATAGCCATTTTTTACGTAAGGCGTCGCGTATCTC
GCTGGCCCCGGGCAATTTATGGGGTGAACAGGCGCGTGGGACTAATGCCATCGGCACTGCGCTGGCATTGGGCGGTTTGT
GTGAAGTTAATGGCGATGAGCACTTTCTCAACCAAAATGCCGGGCTTTACTGCTCAGCCGCGCCGATTTACCGGCCAGAC
GGCCTGATTGCCGGGGTACTGGACATCTCGACGCCCGCGCAACGGCCTTTTGATGACGCGCGTTCATTGATCCTGCAGGC
TGTCAGGCACATAGAACACCAGTGGGTGATGGGCTGCGTGACGTCTCAGCACTGGACGTTACGCCTGCACAGCGATGCGC
GGGTGCTTGGCAGCGCCCATGAGCTGATACTGGTGTTTCGCGACGAGGTTCTCACCGCCGCCAACCGGCTGGCAATGCAG
GAATTTAATCTCTCCGCCGCTTCTTTTGGCACCCTTGACTTCGCCACGCTGTTCCCGGAAATGCAGCGTCAGACGCTGAA
CGCGCCACGCCAAACGCTGGCGGTCAATAATCGCCACTATTATTCGCTGTTGCAGATGCCGGAACGGCATTCGCAGGTCG
TCCGGCCTCGGGAATTGCCCTTTGATCGGGACGGTGCCGACAGACAAAAAGCATTACGTATTTTGAATGCCGGGCTGGCG
CTGTGCATAAGTGGGGAAACCGGCTGTGGCAAAGAGTATTTCAGCCAACGGCTGTTCGAGGAAAGTCATCGGCGGCAGGG
CAATTTTGTGGCGATCAACTGTGCCGCGCTGCCGGAAAACCTGATCGAATCAGAGCTTTTTGGCTATGCGCCCGGTGCCT
TTACCGGTGCCAACCCAAAAGGGTACCTCGGCAAGATCAGAGAGGCCGACGGTGGCGTACTGTTTCTGGATGAAATCGGC
GATATGCCATTGAGTTTACAGACCCGACTGCTGCGGGTGCTGCAGGAAAAAACGGTCACGCCGCTCGGCAGCCGTCTCAG
CTATGCCGTCGACTTTTCGCTTATTTGCGCGACCCATCAGGATTTGGCGCAGCAGGTGGCGGCGGGGGCGTTCCGTGAAG
ATTTGATGTACCGGATTCAGGAATTCAACCTGCGTATTTTACCGCTGCGCCAACGGGCACACGTCGATCGTTTTATCCTT
AATCTGTGGCAAGAATTGGGTGCCGAGTCTCGGAGTATCCGGCTGGCGCCGGAGACCGTCGCGGTGCTGGCACGCTATCC
GTGGCCCGGTAACGTTCGGCAGTTGTTGAGTACGTTGAAGGTGCTGTTGGCCCTGGCGGATGATGGCGAGCTGATTACGC
CTGACGCACTCCCCGAGCAGTTTGGCGTCTTACCGCTGCCCGCTGATCCCCACGCCGCACCGCAGGAGATGCTGGACGCT
ATCCGAAGCGCTAATGGCAATATCAGCCTGGCGGCGAAACGGCTGGGTGTTTCACGCAGTACGCTTTATCGCAAGATGGA
GAAAAGCCGTGGGCGGGCAGTAGAATGA

Upstream 100 bases:

>100_bases
GGCTTATTATTCATTTCTATTATTTTTTGTGTCCCATGTCGCAACGCATGCGACACATTCGTGATACAAAAATGCAACAC
TTTATTGACGGGAGTCGGGC

Downstream 100 bases:

>100_bases
CCGCCCAATCGACAAGGCCCCTTTCAGGGCCAAGGCCGGAGGGTTAGTTGTCGCCCAGCCCCTGTGGATTAATTTCAGAA
TGTTCGATTTTCTCGTCGCT

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MLQKDQTGFVSDSDNLSLPGPLSESWLRSRHYGLDRTDDLVPFVRPALLNEVRGQNGWVAQLARPLIERLGGEINRQPSI
VVVSDAKGLVLETCGNSHFLRKASRISLAPGNLWGEQARGTNAIGTALALGGLCEVNGDEHFLNQNAGLYCSAAPIYRPD
GLIAGVLDISTPAQRPFDDARSLILQAVRHIEHQWVMGCVTSQHWTLRLHSDARVLGSAHELILVFRDEVLTAANRLAMQ
EFNLSAASFGTLDFATLFPEMQRQTLNAPRQTLAVNNRHYYSLLQMPERHSQVVRPRELPFDRDGADRQKALRILNAGLA
LCISGETGCGKEYFSQRLFEESHRRQGNFVAINCAALPENLIESELFGYAPGAFTGANPKGYLGKIREADGGVLFLDEIG
DMPLSLQTRLLRVLQEKTVTPLGSRLSYAVDFSLICATHQDLAQQVAAGAFREDLMYRIQEFNLRILPLRQRAHVDRFIL
NLWQELGAESRSIRLAPETVAVLARYPWPGNVRQLLSTLKVLLALADDGELITPDALPEQFGVLPLPADPHAAPQEMLDA
IRSANGNISLAAKRLGVSRSTLYRKMEKSRGRAVE

Sequences:

>Translated_595_residues
MLQKDQTGFVSDSDNLSLPGPLSESWLRSRHYGLDRTDDLVPFVRPALLNEVRGQNGWVAQLARPLIERLGGEINRQPSI
VVVSDAKGLVLETCGNSHFLRKASRISLAPGNLWGEQARGTNAIGTALALGGLCEVNGDEHFLNQNAGLYCSAAPIYRPD
GLIAGVLDISTPAQRPFDDARSLILQAVRHIEHQWVMGCVTSQHWTLRLHSDARVLGSAHELILVFRDEVLTAANRLAMQ
EFNLSAASFGTLDFATLFPEMQRQTLNAPRQTLAVNNRHYYSLLQMPERHSQVVRPRELPFDRDGADRQKALRILNAGLA
LCISGETGCGKEYFSQRLFEESHRRQGNFVAINCAALPENLIESELFGYAPGAFTGANPKGYLGKIREADGGVLFLDEIG
DMPLSLQTRLLRVLQEKTVTPLGSRLSYAVDFSLICATHQDLAQQVAAGAFREDLMYRIQEFNLRILPLRQRAHVDRFIL
NLWQELGAESRSIRLAPETVAVLARYPWPGNVRQLLSTLKVLLALADDGELITPDALPEQFGVLPLPADPHAAPQEMLDA
IRSANGNISLAAKRLGVSRSTLYRKMEKSRGRAVE
>Mature_595_residues
MLQKDQTGFVSDSDNLSLPGPLSESWLRSRHYGLDRTDDLVPFVRPALLNEVRGQNGWVAQLARPLIERLGGEINRQPSI
VVVSDAKGLVLETCGNSHFLRKASRISLAPGNLWGEQARGTNAIGTALALGGLCEVNGDEHFLNQNAGLYCSAAPIYRPD
GLIAGVLDISTPAQRPFDDARSLILQAVRHIEHQWVMGCVTSQHWTLRLHSDARVLGSAHELILVFRDEVLTAANRLAMQ
EFNLSAASFGTLDFATLFPEMQRQTLNAPRQTLAVNNRHYYSLLQMPERHSQVVRPRELPFDRDGADRQKALRILNAGLA
LCISGETGCGKEYFSQRLFEESHRRQGNFVAINCAALPENLIESELFGYAPGAFTGANPKGYLGKIREADGGVLFLDEIG
DMPLSLQTRLLRVLQEKTVTPLGSRLSYAVDFSLICATHQDLAQQVAAGAFREDLMYRIQEFNLRILPLRQRAHVDRFIL
NLWQELGAESRSIRLAPETVAVLARYPWPGNVRQLLSTLKVLLALADDGELITPDALPEQFGVLPLPADPHAAPQEMLDA
IRSANGNISLAAKRLGVSRSTLYRKMEKSRGRAVE

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=300, Percent_Identity=37.3333333333333, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1790299, Length=313, Percent_Identity=38.6581469648562, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1788905, Length=290, Percent_Identity=39.3103448275862, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1790437, Length=279, Percent_Identity=38.3512544802867, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1786524, Length=308, Percent_Identity=40.2597402597403, Blast_Score=179, Evalue=7e-46,
Organism=Escherichia coli, GI1789087, Length=289, Percent_Identity=39.1003460207612, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1788550, Length=288, Percent_Identity=35.7638888888889, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI87082117, Length=293, Percent_Identity=38.5665529010239, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI87082152, Length=228, Percent_Identity=42.5438596491228, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1787583, Length=283, Percent_Identity=34.6289752650177, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87081872, Length=209, Percent_Identity=38.755980861244, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1789828, Length=301, Percent_Identity=33.2225913621262, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081858, Length=280, Percent_Identity=29.6428571428571, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 65839; Mature: 65839

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKDQTGFVSDSDNLSLPGPLSESWLRSRHYGLDRTDDLVPFVRPALLNEVRGQNGWVA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHH
QLARPLIERLGGEINRQPSIVVVSDAKGLVLETCGNSHFLRKASRISLAPGNLWGEQARG
HHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCC
TNAIGTALALGGLCEVNGDEHFLNQNAGLYCSAAPIYRPDGLIAGVLDISTPAQRPFDDA
CCHHHHHHHHCCEEEECCCHHHHCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCHHHH
RSLILQAVRHIEHQWVMGCVTSQHWTLRLHSDARVLGSAHELILVFRDEVLTAANRLAMQ
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCHHHEEEEEHHHHHHHHHHHHHH
EFNLSAASFGTLDFATLFPEMQRQTLNAPRQTLAVNNRHYYSLLQMPERHSQVVRPRELP
HHCCCHHCCCCHHHHHHHHHHHHHHHCCCHHHEEECCCHHHHHHHCCHHHHHCCCCCCCC
FDRDGADRQKALRILNAGLALCISGETGCGKEYFSQRLFEESHRRQGNFVAINCAALPEN
CCCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHCCHH
LIESELFGYAPGAFTGANPKGYLGKIREADGGVLFLDEIGDMPLSLQTRLLRVLQEKTVT
HHHHHHHCCCCCCCCCCCCCCHHHHHEECCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
PLGSRLSYAVDFSLICATHQDLAQQVAAGAFREDLMYRIQEFNLRILPLRQRAHVDRFIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHH
NLWQELGAESRSIRLAPETVAVLARYPWPGNVRQLLSTLKVLLALADDGELITPDALPEQ
HHHHHHCCCCCEEEECHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCHHH
FGVLPLPADPHAAPQEMLDAIRSANGNISLAAKRLGVSRSTLYRKMEKSRGRAVE
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLQKDQTGFVSDSDNLSLPGPLSESWLRSRHYGLDRTDDLVPFVRPALLNEVRGQNGWVA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHH
QLARPLIERLGGEINRQPSIVVVSDAKGLVLETCGNSHFLRKASRISLAPGNLWGEQARG
HHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCC
TNAIGTALALGGLCEVNGDEHFLNQNAGLYCSAAPIYRPDGLIAGVLDISTPAQRPFDDA
CCHHHHHHHHCCEEEECCCHHHHCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCHHHH
RSLILQAVRHIEHQWVMGCVTSQHWTLRLHSDARVLGSAHELILVFRDEVLTAANRLAMQ
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCHHHEEEEEHHHHHHHHHHHHHH
EFNLSAASFGTLDFATLFPEMQRQTLNAPRQTLAVNNRHYYSLLQMPERHSQVVRPRELP
HHCCCHHCCCCHHHHHHHHHHHHHHHCCCHHHEEECCCHHHHHHHCCHHHHHCCCCCCCC
FDRDGADRQKALRILNAGLALCISGETGCGKEYFSQRLFEESHRRQGNFVAINCAALPEN
CCCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHCCHH
LIESELFGYAPGAFTGANPKGYLGKIREADGGVLFLDEIGDMPLSLQTRLLRVLQEKTVT
HHHHHHHCCCCCCCCCCCCCCHHHHHEECCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
PLGSRLSYAVDFSLICATHQDLAQQVAAGAFREDLMYRIQEFNLRILPLRQRAHVDRFIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHH
NLWQELGAESRSIRLAPETVAVLARYPWPGNVRQLLSTLKVLLALADDGELITPDALPEQ
HHHHHHCCCCCEEEECHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCHHH
FGVLPLPADPHAAPQEMLDAIRSANGNISLAAKRLGVSRSTLYRKMEKSRGRAVE
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]