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The map label for this gene is bglC [H]

Identifier: 157370564

GI number: 157370564

Start: 2538048

End: 2539460

Strand: Direct

Name: bglC [H]

Synonym: Spro_2324

Alternate gene names: 157370564

Gene position: 2538048-2539460 (Clockwise)

Preceding gene: 157370563

Following gene: 157370565

Centisome position: 46.58

GC content: 56.55

Gene sequence:

>1413_bases
ATGATTTATCAACGACTGAACGATTTCCCCAAAGATTTTCTGTGGGGGGCTTCTACCTCCGCCTATCAGGTAGAAGGGGC
CTGGGACGAAGATGGCAAAAGCCCGTCGATTGTAGATATGCTCGATCATCCGCCAGGCACCGCCGACTTTAAGGTGGCCA
GCGATCACTATCATCGCTTTCGCGAGGACGTGAAACTGTTTGCCGAGTTGGGGCTGAAGGCCTATCGCTTTTCCATTGCC
TGGACGCGGGTGCTGCCCAATGGCACTGGCGAGGTCAACGCTGCCGGGCTGAATTTCTACCGCCAGTTGATTGATGAACT
GCTGAGCCATGGCATCGAGCCGGTGGTGACGCTGTATCATTTCGATCTGCCCTATGTGCTTGAGCAGCAGGGGGGCTGGT
CTAATCGCGCCACCATCGACGCCTTTGTCGATTATGCCGGGGTGCTGTTCGACGCCTTTGGCGACCGGGTGAAGTACTGG
CTGACTATCAACGAACAAAACACCATGATCCTGCACCCTGGGGCGATTGGTACGCCAAAGGGTGGCGTACTGCCGTCCAA
ACGGGTGTTGTATCAGCAAAGCCACCATATGCTGGTGGCTCAGGCGCGGGTGATGGCGCTGTGTCACCAGCGCTGCCCCG
CAGGGAAGATTGGCCCGGCGATTAACACCACCTCGATGTATCAGGAAACCTGCCATCCGCTGGATGCTATCGCCGCCCAT
AACTGGGAGACGCTGCGTTGCTGGAGTTTCCTCGACGTGGCGGTGCATGGCCGCTACAACCCGCTGGCCTGGCGTTATTT
GCTGGACCGCGAACTGGCTCCGCAGATGGAGCCGGGCGATGCGGCGCTGTTGCTGCAGGGCAAACCGGACTATGTGGCGA
TAAACTACTATTCTACCGCCACCATTGCCGCCAGCCGTGGCGACGCCTCCGATATCAGCGCACGCGCCGGCGATCAGCAA
ATCATGCTGGGGGAATCGGGAGTTTACCGTGCAGCAGAGAATCCGTTCGTCGGTAAAACCCGCTACGGCTGGGTGATCGA
CCCGGTCGGATTACGGCTAACGCTGCGCAAAACCGCTGAACGCTATCATTTGCCAATATTAATTACTGAAAACGGCATCG
GTGCTCCGGATGAGTTACAGGCCGATGGTACAATTAACGACGATTACCGCATTGAGTTTATGCGTCAGCATGTCGAACAG
ATGCAGTTGGCGATTAACGACGGGGTAGAACTGATCGGCTATTGTCCGTGGGCGGCGATAGACGTGGTCAGCACTCATCA
GGGCTATGCCAAGCGTTACGGGTTTGTCTATGTCAACCGGGGTGAGCAGGGTCTGAAAGATCTGCGGAGAATTAAAAAAC
GCAGTTTTGACTGGTATCAACGGCTGATTGCCTCCGATGGCCGGCAACGCTAA

Upstream 100 bases:

>100_bases
TCAACAGCGAAGATTTCCCGCAGTTGAGTTGCCGTCAGCCGGGTCGGATCGGCTTTGGCGAACCCATCATCAGCCTGAAT
AATGCGCAGCAGGAGCCGGC

Downstream 100 bases:

>100_bases
AAAATAAAGGGTGATGGCCGCGACGATGAAAGTCATTAAGGTACTCAATAATAGCCTGGTGCTATCGACTGACGGCGATA
ACAATGAAGTTATCGTGATG

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MIYQRLNDFPKDFLWGASTSAYQVEGAWDEDGKSPSIVDMLDHPPGTADFKVASDHYHRFREDVKLFAELGLKAYRFSIA
WTRVLPNGTGEVNAAGLNFYRQLIDELLSHGIEPVVTLYHFDLPYVLEQQGGWSNRATIDAFVDYAGVLFDAFGDRVKYW
LTINEQNTMILHPGAIGTPKGGVLPSKRVLYQQSHHMLVAQARVMALCHQRCPAGKIGPAINTTSMYQETCHPLDAIAAH
NWETLRCWSFLDVAVHGRYNPLAWRYLLDRELAPQMEPGDAALLLQGKPDYVAINYYSTATIAASRGDASDISARAGDQQ
IMLGESGVYRAAENPFVGKTRYGWVIDPVGLRLTLRKTAERYHLPILITENGIGAPDELQADGTINDDYRIEFMRQHVEQ
MQLAINDGVELIGYCPWAAIDVVSTHQGYAKRYGFVYVNRGEQGLKDLRRIKKRSFDWYQRLIASDGRQR

Sequences:

>Translated_470_residues
MIYQRLNDFPKDFLWGASTSAYQVEGAWDEDGKSPSIVDMLDHPPGTADFKVASDHYHRFREDVKLFAELGLKAYRFSIA
WTRVLPNGTGEVNAAGLNFYRQLIDELLSHGIEPVVTLYHFDLPYVLEQQGGWSNRATIDAFVDYAGVLFDAFGDRVKYW
LTINEQNTMILHPGAIGTPKGGVLPSKRVLYQQSHHMLVAQARVMALCHQRCPAGKIGPAINTTSMYQETCHPLDAIAAH
NWETLRCWSFLDVAVHGRYNPLAWRYLLDRELAPQMEPGDAALLLQGKPDYVAINYYSTATIAASRGDASDISARAGDQQ
IMLGESGVYRAAENPFVGKTRYGWVIDPVGLRLTLRKTAERYHLPILITENGIGAPDELQADGTINDDYRIEFMRQHVEQ
MQLAINDGVELIGYCPWAAIDVVSTHQGYAKRYGFVYVNRGEQGLKDLRRIKKRSFDWYQRLIASDGRQR
>Mature_470_residues
MIYQRLNDFPKDFLWGASTSAYQVEGAWDEDGKSPSIVDMLDHPPGTADFKVASDHYHRFREDVKLFAELGLKAYRFSIA
WTRVLPNGTGEVNAAGLNFYRQLIDELLSHGIEPVVTLYHFDLPYVLEQQGGWSNRATIDAFVDYAGVLFDAFGDRVKYW
LTINEQNTMILHPGAIGTPKGGVLPSKRVLYQQSHHMLVAQARVMALCHQRCPAGKIGPAINTTSMYQETCHPLDAIAAH
NWETLRCWSFLDVAVHGRYNPLAWRYLLDRELAPQMEPGDAALLLQGKPDYVAINYYSTATIAASRGDASDISARAGDQQ
IMLGESGVYRAAENPFVGKTRYGWVIDPVGLRLTLRKTAERYHLPILITENGIGAPDELQADGTINDDYRIEFMRQHVEQ
MQLAINDGVELIGYCPWAAIDVVSTHQGYAKRYGFVYVNRGEQGLKDLRRIKKRSFDWYQRLIASDGRQR

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=480, Percent_Identity=33.3333333333333, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI13273313, Length=488, Percent_Identity=32.3770491803279, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI110681710, Length=488, Percent_Identity=29.9180327868852, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI24497614, Length=484, Percent_Identity=30.7851239669421, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI28376633, Length=470, Percent_Identity=30, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI190360571, Length=131, Percent_Identity=38.1679389312977, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI2367174, Length=494, Percent_Identity=39.6761133603239, Blast_Score=357, Evalue=1e-99,
Organism=Escherichia coli, GI2367270, Length=477, Percent_Identity=40.461215932914, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1789070, Length=483, Percent_Identity=37.888198757764, Blast_Score=325, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI17552856, Length=479, Percent_Identity=29.8538622129436, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17539390, Length=478, Percent_Identity=27.1966527196653, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21356577, Length=481, Percent_Identity=28.8981288981289, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53067; Mature: 53067

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYQRLNDFPKDFLWGASTSAYQVEGAWDEDGKSPSIVDMLDHPPGTADFKVASDHYHRF
CCCHHHHCCCHHHHCCCCCCCEEEECCCCCCCCCCCEEEHHCCCCCCCCEEECHHHHHHH
REDVKLFAELGLKAYRFSIAWTRVLPNGTGEVNAAGLNFYRQLIDELLSHGIEPVVTLYH
HHHHHHHHHHCCEEEEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEEE
FDLPYVLEQQGGWSNRATIDAFVDYAGVLFDAFGDRVKYWLTINEQNTMILHPGAIGTPK
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCC
GGVLPSKRVLYQQSHHMLVAQARVMALCHQRCPAGKIGPAINTTSMYQETCHPLDAIAAH
CCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHC
NWETLRCWSFLDVAVHGRYNPLAWRYLLDRELAPQMEPGDAALLLQGKPDYVAINYYSTA
CCCEEEHHHEEEHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEEEEE
TIAASRGDASDISARAGDQQIMLGESGVYRAAENPFVGKTRYGWVIDPVGLRLTLRKTAE
EEEECCCCCCHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCEEECCCCCEEEEEHHHH
RYHLPILITENGIGAPDELQADGTINDDYRIEFMRQHVEQMQLAINDGVELIGYCPWAAI
HEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHE
DVVSTHQGYAKRYGFVYVNRGEQGLKDLRRIKKRSFDWYQRLIASDGRQR
EHHHCCCCHHHHCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIYQRLNDFPKDFLWGASTSAYQVEGAWDEDGKSPSIVDMLDHPPGTADFKVASDHYHRF
CCCHHHHCCCHHHHCCCCCCCEEEECCCCCCCCCCCEEEHHCCCCCCCCEEECHHHHHHH
REDVKLFAELGLKAYRFSIAWTRVLPNGTGEVNAAGLNFYRQLIDELLSHGIEPVVTLYH
HHHHHHHHHHCCEEEEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEEE
FDLPYVLEQQGGWSNRATIDAFVDYAGVLFDAFGDRVKYWLTINEQNTMILHPGAIGTPK
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCC
GGVLPSKRVLYQQSHHMLVAQARVMALCHQRCPAGKIGPAINTTSMYQETCHPLDAIAAH
CCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHC
NWETLRCWSFLDVAVHGRYNPLAWRYLLDRELAPQMEPGDAALLLQGKPDYVAINYYSTA
CCCEEEHHHEEEHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEEEEE
TIAASRGDASDISARAGDQQIMLGESGVYRAAENPFVGKTRYGWVIDPVGLRLTLRKTAE
EEEECCCCCCHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCEEECCCCCEEEEEHHHH
RYHLPILITENGIGAPDELQADGTINDDYRIEFMRQHVEQMQLAINDGVELIGYCPWAAI
HEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHE
DVVSTHQGYAKRYGFVYVNRGEQGLKDLRRIKKRSFDWYQRLIASDGRQR
EHHHCCCCHHHHCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]