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The map label for this gene is iorA [H]

Identifier: 157370554

GI number: 157370554

Start: 2520614

End: 2521156

Strand: Direct

Name: iorA [H]

Synonym: Spro_2314

Alternate gene names: 157370554

Gene position: 2520614-2521156 (Clockwise)

Preceding gene: 157370553

Following gene: 157370555

Centisome position: 46.26

GC content: 59.67

Gene sequence:

>543_bases
ATGGCGATAGCTGAAGTGCAATTGCCCAGGGAAGGCGCGGTAAAAACACTGACGGAGCATCCGCTGATGCTGTCAGTCAA
CGGCGAAAATATTCATACCCGGGTAATGGCGGATACTCCTCTGCTATTGGTGTTACGTAACGATCTGGCGCTCAACGGCC
CGAAATACGGCTGTGGCCTGGGTGAGTGCGGAGCCTGTACCGTGTTGGTCGACGGCATTGCCGCACGCTCTTGTGTGATC
CCGGCGCTGGGTATGACCGGCCGCGTGGTGACCACGCTGGAAGGTTTGGGCGATCGCGATCGTCTGCACCCGGTGCAACG
TGCCTTTATCGAAGAACAGGCCGCGCAGTGCGGTTACTGCCTCAATGGCATGATCATGACCACCAAAGCCCTGTTGGATC
GCAATCCGTCGCCCAGCGACCGCGAAATCCGCCAGGCGCTGTCCGGCAACCTGTGCCGCTGCGGCACCCATATCGAAATC
CTGCGTGCGGTTCAGCGCGCCATCATTCTCTGCCGCAGTGAGGAAACCTCGCCCCATGACTGA

Upstream 100 bases:

>100_bases
GGAAGACCAGCCGCCCGGCTGATTCGCCACCCGCAACTGCGGTTGTCTGGTGAGTGCGGTGGGCCGACACAATAACCAGA
GCGCAGGCGGAGACGCAACA

Downstream 100 bases:

>100_bases
CGCCCATTCCTCAGTACCGAGCCAGGCTGAATTATTGCAGCGTCATGGCACCTTGCTGGTTATCGATCAGATCCAACCGC
CGCCGGGGCTGGTGCCGAAA

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MAIAEVQLPREGAVKTLTEHPLMLSVNGENIHTRVMADTPLLLVLRNDLALNGPKYGCGLGECGACTVLVDGIAARSCVI
PALGMTGRVVTTLEGLGDRDRLHPVQRAFIEEQAAQCGYCLNGMIMTTKALLDRNPSPSDREIRQALSGNLCRCGTHIEI
LRAVQRAIILCRSEETSPHD

Sequences:

>Translated_180_residues
MAIAEVQLPREGAVKTLTEHPLMLSVNGENIHTRVMADTPLLLVLRNDLALNGPKYGCGLGECGACTVLVDGIAARSCVI
PALGMTGRVVTTLEGLGDRDRLHPVQRAFIEEQAAQCGYCLNGMIMTTKALLDRNPSPSDREIRQALSGNLCRCGTHIEI
LRAVQRAIILCRSEETSPHD
>Mature_179_residues
AIAEVQLPREGAVKTLTEHPLMLSVNGENIHTRVMADTPLLLVLRNDLALNGPKYGCGLGECGACTVLVDGIAARSCVIP
ALGMTGRVVTTLEGLGDRDRLHPVQRAFIEEQAAQCGYCLNGMIMTTKALLDRNPSPSDREIRQALSGNLCRCGTHIEIL
RAVQRAIILCRSEETSPHD

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=161, Percent_Identity=37.2670807453416, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI71773480, Length=105, Percent_Identity=38.0952380952381, Blast_Score=80, Evalue=9e-16,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=42.5925925925926, Blast_Score=123, Evalue=6e-30,
Organism=Escherichia coli, GI1789232, Length=142, Percent_Identity=42.2535211267606, Blast_Score=100, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=153, Percent_Identity=40.5228758169935, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=37.012987012987, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=35.0649350649351, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17737937, Length=157, Percent_Identity=40.1273885350318, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24647193, Length=141, Percent_Identity=32.6241134751773, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647197, Length=140, Percent_Identity=34.2857142857143, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647195, Length=140, Percent_Identity=34.2857142857143, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24647199, Length=139, Percent_Identity=30.9352517985612, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 19442; Mature: 19311

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIAEVQLPREGAVKTLTEHPLMLSVNGENIHTRVMADTPLLLVLRNDLALNGPKYGCGL
CCCCCCCCCCCCCHHHHCCCCEEEEECCCCEEEEEEECCCEEEEEECCCEECCCCCCCCC
GECGACTVLVDGIAARSCVIPALGMTGRVVTTLEGLGDRDRLHPVQRAFIEEQAAQCGYC
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHH
LNGMIMTTKALLDRNPSPSDREIRQALSGNLCRCGTHIEILRAVQRAIILCRSEETSPHD
HCCHHHHHHHHHCCCCCCCHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AIAEVQLPREGAVKTLTEHPLMLSVNGENIHTRVMADTPLLLVLRNDLALNGPKYGCGL
CCCCCCCCCCCCHHHHCCCCEEEEECCCCEEEEEEECCCEEEEEECCCEECCCCCCCCC
GECGACTVLVDGIAARSCVIPALGMTGRVVTTLEGLGDRDRLHPVQRAFIEEQAAQCGYC
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHH
LNGMIMTTKALLDRNPSPSDREIRQALSGNLCRCGTHIEILRAVQRAIILCRSEETSPHD
HCCHHHHHHHHHCCCCCCCHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]