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The map label for this gene is ttuB [H]

Identifier: 157370547

GI number: 157370547

Start: 2513827

End: 2515134

Strand: Reverse

Name: ttuB [H]

Synonym: Spro_2307

Alternate gene names: 157370547

Gene position: 2515134-2513827 (Counterclockwise)

Preceding gene: 157370548

Following gene: 157370545

Centisome position: 46.16

GC content: 58.41

Gene sequence:

>1308_bases
ATGGCCATTGTTGAAACCCCGTTAGCCGGGAAAGCGGGCGCAGAATCGCTTCTGTACCGCAAAATCACCTGGAAGCTGAT
CCCGTTCCTCTGTCTGTGCTATTTGGCCGCCTACCTCGACCGCATCAATGTCGGGCTAGCCAAGCTGCAGATGGCCGATC
AACTGCAACTGAGCGAAGCGGCCTTCGGCCTGGGCGCCGGGCTGTTTTTTGTCGGCTATATCCTGTTTGAGGTGCCGAGC
AACCTGATCCTGCAACGGGTCGGCGCCAAGGTGTGGATTGCCCGCATCATGATCACCTGGGGCCTGCTTTCCGCCTGCAC
CATGTTCGTTACCACCCCCAATCAGTTTTACGTCATCCGCTTTCTGCTCGGCGTGGCGGAGGCCGGTTTTCTGCCCGGCG
TGCTGTATTACCTGACGCTGTGGTTCCCGACTTACCGTCGCGGCCGCATTATTGCGTTATTCATGATCGGCCTGCCGCTG
TCGAGCGTGCTCGGTGGCCCGATTTCCGGCTGGATCATGGGGCATTTTGATATGCGCTACGGGCTGCACGGCTGGCAATG
GCTGTTCCTGCTGGAGGGCATCCCCAGCGTGCTGTTGGGTATATTGACGTTCTGGGTGTTACCGAACCATTTCCGGCAGG
CCAAATGGTTATCCGATGAAGAGAAACAACAAATTGCCGACGACCTGGCGCAGGATGACGCCGAGGCCAGTCACAGTAAA
CACAGCTTTCGCGATGGCTTCTTTAATCTCAAGGTCTGGATGCTCGGCGGCATTGATTTTTCGATCCTGCTGAGTGCTTA
TGCAATGGGGTTCTGGATGCCTACCTTTATCAAAACCGCCGGGGTGACCGACATTACCACCATCGGCATGCTGACCGCGC
TACCGAGCATCGCCGCCCTGCTGGGGATGCTGGTGATCGGCAGCAGTTCGGATCGTATGCGTGAGCGGCGCTGGCATATC
ATTGTGCCGTTTATTATTGGCGCGATGGCGATGGCCGGCAGCACCTTCTTCACTCATAGCGTGATCGCCACGGTGTTGTT
GTTCTCTGTGGCCCAGGCGGCGATCATCGGTGCAGTGCCGGTGTTCTTCAGCCTGCCCGCCACCTTCCTGCGCGGTACCG
CAGCGGCAACCGGTTTCGCGCTGGCCTGCTCGTTAGCCAATATTGCCGGGTTGGTGAGTAATTCACTGATGGGGCTGGCG
CTGGATCTGACCGGTAAAAGCGGTGGCGCACTCTGGGCGTTCGCCGGTTGCCTGCTGTTAAGTTCGTTACTGGTGGTCGC
TCTGCCGGCCAAGGTGGTTAACCGCTGA

Upstream 100 bases:

>100_bases
CGGAGTGCTGAAAAATCAAGAAGGCGCGACAAGCGCCTCGAAAGCAAACACACAACGCTCCTCCTCCGGAGGCCACTATG
CACCACCTGGAGACATCATC

Downstream 100 bases:

>100_bases
GACCAGGGGGCGCGAGTTTCCGCACCCCTGCTTCACTCCTTAATCTCAACCAAACTGCTTATAACAAATAAAGAGGGCGT
AATTTCTTACGCCCTCTTAT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MAIVETPLAGKAGAESLLYRKITWKLIPFLCLCYLAAYLDRINVGLAKLQMADQLQLSEAAFGLGAGLFFVGYILFEVPS
NLILQRVGAKVWIARIMITWGLLSACTMFVTTPNQFYVIRFLLGVAEAGFLPGVLYYLTLWFPTYRRGRIIALFMIGLPL
SSVLGGPISGWIMGHFDMRYGLHGWQWLFLLEGIPSVLLGILTFWVLPNHFRQAKWLSDEEKQQIADDLAQDDAEASHSK
HSFRDGFFNLKVWMLGGIDFSILLSAYAMGFWMPTFIKTAGVTDITTIGMLTALPSIAALLGMLVIGSSSDRMRERRWHI
IVPFIIGAMAMAGSTFFTHSVIATVLLFSVAQAAIIGAVPVFFSLPATFLRGTAAATGFALACSLANIAGLVSNSLMGLA
LDLTGKSGGALWAFAGCLLLSSLLVVALPAKVVNR

Sequences:

>Translated_435_residues
MAIVETPLAGKAGAESLLYRKITWKLIPFLCLCYLAAYLDRINVGLAKLQMADQLQLSEAAFGLGAGLFFVGYILFEVPS
NLILQRVGAKVWIARIMITWGLLSACTMFVTTPNQFYVIRFLLGVAEAGFLPGVLYYLTLWFPTYRRGRIIALFMIGLPL
SSVLGGPISGWIMGHFDMRYGLHGWQWLFLLEGIPSVLLGILTFWVLPNHFRQAKWLSDEEKQQIADDLAQDDAEASHSK
HSFRDGFFNLKVWMLGGIDFSILLSAYAMGFWMPTFIKTAGVTDITTIGMLTALPSIAALLGMLVIGSSSDRMRERRWHI
IVPFIIGAMAMAGSTFFTHSVIATVLLFSVAQAAIIGAVPVFFSLPATFLRGTAAATGFALACSLANIAGLVSNSLMGLA
LDLTGKSGGALWAFAGCLLLSSLLVVALPAKVVNR
>Mature_434_residues
AIVETPLAGKAGAESLLYRKITWKLIPFLCLCYLAAYLDRINVGLAKLQMADQLQLSEAAFGLGAGLFFVGYILFEVPSN
LILQRVGAKVWIARIMITWGLLSACTMFVTTPNQFYVIRFLLGVAEAGFLPGVLYYLTLWFPTYRRGRIIALFMIGLPLS
SVLGGPISGWIMGHFDMRYGLHGWQWLFLLEGIPSVLLGILTFWVLPNHFRQAKWLSDEEKQQIADDLAQDDAEASHSKH
SFRDGFFNLKVWMLGGIDFSILLSAYAMGFWMPTFIKTAGVTDITTIGMLTALPSIAALLGMLVIGSSSDRMRERRWHII
VPFIIGAMAMAGSTFFTHSVIATVLLFSVAQAAIIGAVPVFFSLPATFLRGTAAATGFALACSLANIAGLVSNSLMGLAL
DLTGKSGGALWAFAGCLLLSSLLVVALPAKVVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=274, Percent_Identity=22.2627737226277, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87082071, Length=417, Percent_Identity=34.7721822541966, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI2367379, Length=281, Percent_Identity=26.6903914590747, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789515, Length=295, Percent_Identity=24.406779661017, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789152, Length=297, Percent_Identity=23.5690235690236, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI2367193, Length=291, Percent_Identity=22.680412371134, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082320, Length=292, Percent_Identity=22.9452054794521, Blast_Score=68, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=376, Percent_Identity=23.1382978723404, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321698, Length=320, Percent_Identity=24.375, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=242, Percent_Identity=26.4462809917355, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323032, Length=326, Percent_Identity=25.7668711656442, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319250, Length=343, Percent_Identity=23.9067055393586, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=246, Percent_Identity=23.5772357723577, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=175, Percent_Identity=26.2857142857143, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20130167, Length=305, Percent_Identity=21.3114754098361, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584153, Length=265, Percent_Identity=23.0188679245283, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47353; Mature: 47222

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVETPLAGKAGAESLLYRKITWKLIPFLCLCYLAAYLDRINVGLAKLQMADQLQLSEA
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGLGAGLFFVGYILFEVPSNLILQRVGAKVWIARIMITWGLLSACTMFVTTPNQFYVIR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHH
FLLGVAEAGFLPGVLYYLTLWFPTYRRGRIIALFMIGLPLSSVLGGPISGWIMGHFDMRY
HHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCHHHHHCCCCHHHEEEEEHHHH
GLHGWQWLFLLEGIPSVLLGILTFWVLPNHFRQAKWLSDEEKQQIADDLAQDDAEASHSK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCH
HSFRDGFFNLKVWMLGGIDFSILLSAYAMGFWMPTFIKTAGVTDITTIGMLTALPSIAAL
HHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LGMLVIGSSSDRMRERRWHIIVPFIIGAMAMAGSTFFTHSVIATVLLFSVAQAAIIGAVP
HHHHHHCCCHHHHHHCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VFFSLPATFLRGTAAATGFALACSLANIAGLVSNSLMGLALDLTGKSGGALWAFAGCLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHH
SSLLVVALPAKVVNR
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIVETPLAGKAGAESLLYRKITWKLIPFLCLCYLAAYLDRINVGLAKLQMADQLQLSEA
CEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGLGAGLFFVGYILFEVPSNLILQRVGAKVWIARIMITWGLLSACTMFVTTPNQFYVIR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHH
FLLGVAEAGFLPGVLYYLTLWFPTYRRGRIIALFMIGLPLSSVLGGPISGWIMGHFDMRY
HHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCHHHHHCCCCHHHEEEEEHHHH
GLHGWQWLFLLEGIPSVLLGILTFWVLPNHFRQAKWLSDEEKQQIADDLAQDDAEASHSK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCH
HSFRDGFFNLKVWMLGGIDFSILLSAYAMGFWMPTFIKTAGVTDITTIGMLTALPSIAAL
HHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LGMLVIGSSSDRMRERRWHIIVPFIIGAMAMAGSTFFTHSVIATVLLFSVAQAAIIGAVP
HHHHHHCCCHHHHHHCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VFFSLPATFLRGTAAATGFALACSLANIAGLVSNSLMGLALDLTGKSGGALWAFAGCLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHH
SSLLVVALPAKVVNR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]