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The map label for this gene is ppsA [H]

Identifier: 157370414

GI number: 157370414

Start: 2371722

End: 2374100

Strand: Direct

Name: ppsA [H]

Synonym: Spro_2174

Alternate gene names: 157370414

Gene position: 2371722-2374100 (Clockwise)

Preceding gene: 157370404

Following gene: 157370416

Centisome position: 43.53

GC content: 56.54

Gene sequence:

>2379_bases
ATGTCCAACAATGGCCCAGACTTGCGTAATGTGCTTTGGTACAACCAGCTCGGCATGCACGACGTTGACCGTGTCGGCGG
CAAAAATGCCTCCCTCGGTGAAATGATCACCAATCTTTCCGATTTGGGCGTTGCCGTGCCAAACGGTTTTGCCACCACCG
CGCAGGCGTTTAATGATTTCCTCGAGCAAAGCGGTGTTAACCAGCGCATCTATCAGTTACTGGATCAAACTGACGTTGAC
GATATTGCTCAATTGACCAAGGCGGGCGCACAAATCCGTCAATGGATTATCGACACGCCGTTCCATGCGGAATTCGAGCG
TGAGATTAACCTGGCTTACCAGCAACTGGCCGACGGCGAGCCGGAAGCGTCATTTGCCGTGCGTTCTTCCGCTACCGCAG
AGGACATGCCGGATGCCTCTTTCGCCGGCCAGCAGGAAACCTTCCTCAACGTGCAGGGTATTGACGCCGTCATGGTGGCG
ATTAAGCACGTTTTCGCCTCCCTGTTTAACGACCGCGCCATTTCCTACCGGGTGCATCAGGGTTATGACCACCGCGGCGT
GGCCTTGTCGGCTGGCGTACAGCGCATGGTGCGTTCTGACCTGGCATCTTCCGGCGTCATGTTCACCATCGATACCGAAT
CCGGTTTTGATCAGGTGGTGTTTATCACCTCTGCCTTCGGCCTGGGCGAAATGGTGGTGCAGGGCGCAGTCAACCCGGAC
GAGTTCTATGTGCACAAGCCGACGTTGCTGAGAGGCAACCCGGCTATCGTGCGCCGCAACCTCGGCTCGAAGAAAATCCG
CATGGTGTATGCGCCATCGCAGGATCACGGCAAGCAGGTACAAATTGAAGACGTGCCAGAGCAGCAACGCAATCGTTTCT
CTCTGACCGACGAAGAAGTTCAGGGGCTGGCACATCAGGCACTGCTGATCGAAAAACACTACGGCCGCCCGATGGACATC
GAGTGGGCCAAAGACGGCCATACCGGCAAATTGCTGATCGTGCAGGCCCGTCCGGAAACAGTACGCTCTAACGAGCAAAC
GATGGAGCGTTACCAGCTTAACGCGACCAGCCCGGTGCTGGTGGAAGGGCGCGCTATCGGCCACCGCATTGGCGCAGGTC
CGGTGAAGGTCATCCATAACATCAGCGAGATGGACCGCATTGAGCCAGGCGACGTGCTGGTGACTGACATGACCGACCCG
GATTGGGAACCGATCATGAAGAAAGCCGCCGCCATCGTCACTAACCGTGGCGGCCGTACCTGCCACGCGGCGATCATTGC
GCGTGAACTGGGCATTCCGGCGGTGGTTGGCTGCGGCAACGCGACCGATCTGCTCAAAGAAGGTCAACAGGTCACCGTTT
CTTGTGCAGAAGGCGATACCGGCTTCGTCTACAGCGATATCCTCGATTTTAACGTGCAGAGTTCCGAAGTGACCGAACTG
CCGGATCTGCCGTTAAAAATCATGATGAACGTCGGCAACCCGGACCGCGCCTTTGACTTCGCGCGTTTGCCGAATGAAGG
TGTGGGTCTGGCCCGTCTGGAATTTATCATCAACCGTATGATTGGCGTGCATCCGAAGGCGTTGCTGGAGTTTGACCAGC
AGACTCCGGAGCTGCAGGCGGAAATCAGGACGCTGATGCAGGGCTACGACCATCCGGTCGAGTTCTATGTCGGTCGTTTG
ACGGAAGGGATCGCCACGCTGGGCGCCGCGTTCTGGCCGAAGCGAGTGATCGTGCGCCTGTCCGACTTCAAATCCAATGA
GTATGCCAACCTGGTCGGCGGCGAGAAGTATGAACCGCATGAAGAAAACCCAATGTTGGGCTTCCGCGGTGCCGGTCGTT
ACGTGTCCGACAATTTCCGTGACTGTTTCGCGATGGAATGTGACGCGGTAAAACGCGTGCGTAACGAAATGGGCCTGACC
AACGTTGAGATCATGGTGCCGTTTGTTCGCACGGTGGAGCAGGCGGAAGCGGTGGTGGCCGAATTGGCACGTCAGGGCCT
GAAGCGCGGTGAGAACGGCCTGAAAGTGATCATGATGTGCGAGATCCCATCCAATGCGCTGTTGGCAGATCAGTTCCTGC
AGCACTTTGATGGCTTCTCCATTGGCTCCAACGATATGACTCAGTTAACTCTGGGGCTGGATCGTGACTCGGGCGTGGTC
TCTGAGCTGTTTGACGAGCGAAACGAAGCGGTGAAAATTCTGCTGTCGATGGCGATTCAAGCGGCCAAGCGTCAGGGTAA
ATACGTCGGTATTTGCGGCCAGGGGCCGTCTGACCATGAAGACTTTGCCGAATGGTTGATGGATCAGGGTATTGACAGTC
TGTCGCTCAATCCGGATACCGTGGTGCAAACCTGGGTTAATCTGTCGAAGAGAACATAA

Upstream 100 bases:

>100_bases
ATCATTGTGCTAGTCTGACTCGGCACCGTTTTAGCGGCGCTGAGAAAGCAAGCGAATTAAATCCGTCTATACCCTACTGA
TAGCAATAAGGATTGTCTCG

Downstream 100 bases:

>100_bases
TTTTCGCGATACGGAATAATTATTAAGGCGAAAGCCGTAACTCAGGTTACGGCTTTTTTATTTCTGAATGTAAATAAAAA
GGCGCAGTGAACAAAAGCGG

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 792; Mature: 791

Protein sequence:

>792_residues
MSNNGPDLRNVLWYNQLGMHDVDRVGGKNASLGEMITNLSDLGVAVPNGFATTAQAFNDFLEQSGVNQRIYQLLDQTDVD
DIAQLTKAGAQIRQWIIDTPFHAEFEREINLAYQQLADGEPEASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVA
IKHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFTIDTESGFDQVVFITSAFGLGEMVVQGAVNPD
EFYVHKPTLLRGNPAIVRRNLGSKKIRMVYAPSQDHGKQVQIEDVPEQQRNRFSLTDEEVQGLAHQALLIEKHYGRPMDI
EWAKDGHTGKLLIVQARPETVRSNEQTMERYQLNATSPVLVEGRAIGHRIGAGPVKVIHNISEMDRIEPGDVLVTDMTDP
DWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLLKEGQQVTVSCAEGDTGFVYSDILDFNVQSSEVTEL
PDLPLKIMMNVGNPDRAFDFARLPNEGVGLARLEFIINRMIGVHPKALLEFDQQTPELQAEIRTLMQGYDHPVEFYVGRL
TEGIATLGAAFWPKRVIVRLSDFKSNEYANLVGGEKYEPHEENPMLGFRGAGRYVSDNFRDCFAMECDAVKRVRNEMGLT
NVEIMVPFVRTVEQAEAVVAELARQGLKRGENGLKVIMMCEIPSNALLADQFLQHFDGFSIGSNDMTQLTLGLDRDSGVV
SELFDERNEAVKILLSMAIQAAKRQGKYVGICGQGPSDHEDFAEWLMDQGIDSLSLNPDTVVQTWVNLSKRT

Sequences:

>Translated_792_residues
MSNNGPDLRNVLWYNQLGMHDVDRVGGKNASLGEMITNLSDLGVAVPNGFATTAQAFNDFLEQSGVNQRIYQLLDQTDVD
DIAQLTKAGAQIRQWIIDTPFHAEFEREINLAYQQLADGEPEASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVA
IKHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFTIDTESGFDQVVFITSAFGLGEMVVQGAVNPD
EFYVHKPTLLRGNPAIVRRNLGSKKIRMVYAPSQDHGKQVQIEDVPEQQRNRFSLTDEEVQGLAHQALLIEKHYGRPMDI
EWAKDGHTGKLLIVQARPETVRSNEQTMERYQLNATSPVLVEGRAIGHRIGAGPVKVIHNISEMDRIEPGDVLVTDMTDP
DWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLLKEGQQVTVSCAEGDTGFVYSDILDFNVQSSEVTEL
PDLPLKIMMNVGNPDRAFDFARLPNEGVGLARLEFIINRMIGVHPKALLEFDQQTPELQAEIRTLMQGYDHPVEFYVGRL
TEGIATLGAAFWPKRVIVRLSDFKSNEYANLVGGEKYEPHEENPMLGFRGAGRYVSDNFRDCFAMECDAVKRVRNEMGLT
NVEIMVPFVRTVEQAEAVVAELARQGLKRGENGLKVIMMCEIPSNALLADQFLQHFDGFSIGSNDMTQLTLGLDRDSGVV
SELFDERNEAVKILLSMAIQAAKRQGKYVGICGQGPSDHEDFAEWLMDQGIDSLSLNPDTVVQTWVNLSKRT
>Mature_791_residues
SNNGPDLRNVLWYNQLGMHDVDRVGGKNASLGEMITNLSDLGVAVPNGFATTAQAFNDFLEQSGVNQRIYQLLDQTDVDD
IAQLTKAGAQIRQWIIDTPFHAEFEREINLAYQQLADGEPEASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAI
KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFTIDTESGFDQVVFITSAFGLGEMVVQGAVNPDE
FYVHKPTLLRGNPAIVRRNLGSKKIRMVYAPSQDHGKQVQIEDVPEQQRNRFSLTDEEVQGLAHQALLIEKHYGRPMDIE
WAKDGHTGKLLIVQARPETVRSNEQTMERYQLNATSPVLVEGRAIGHRIGAGPVKVIHNISEMDRIEPGDVLVTDMTDPD
WEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLLKEGQQVTVSCAEGDTGFVYSDILDFNVQSSEVTELP
DLPLKIMMNVGNPDRAFDFARLPNEGVGLARLEFIINRMIGVHPKALLEFDQQTPELQAEIRTLMQGYDHPVEFYVGRLT
EGIATLGAAFWPKRVIVRLSDFKSNEYANLVGGEKYEPHEENPMLGFRGAGRYVSDNFRDCFAMECDAVKRVRNEMGLTN
VEIMVPFVRTVEQAEAVVAELARQGLKRGENGLKVIMMCEIPSNALLADQFLQHFDGFSIGSNDMTQLTLGLDRDSGVVS
ELFDERNEAVKILLSMAIQAAKRQGKYVGICGQGPSDHEDFAEWLMDQGIDSLSLNPDTVVQTWVNLSKRT

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=790, Percent_Identity=83.6708860759494, Blast_Score=1390, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=407, Percent_Identity=27.027027027027, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI48994992, Length=372, Percent_Identity=26.0752688172043, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788726, Length=191, Percent_Identity=32.9842931937173, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1789193, Length=405, Percent_Identity=24.1975308641975, Blast_Score=73, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17564524, Length=343, Percent_Identity=26.8221574344023, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 87607; Mature: 87476

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNGPDLRNVLWYNQLGMHDVDRVGGKNASLGEMITNLSDLGVAVPNGFATTAQAFNDF
CCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHCCEECCCCCHHHHHHHHHH
LEQSGVNQRIYQLLDQTDVDDIAQLTKAGAQIRQWIIDTPFHAEFEREINLAYQQLADGE
HHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
PEASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAIKHVFASLFNDRAISYRVHQ
CCCCEEECCCCCCCCCCCCCCCCCCHHEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEC
GYDHRGVALSAGVQRMVRSDLASSGVMFTIDTESGFDQVVFITSAFGLGEMVVQGAVNPD
CCCCCCEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCHHHHHHHCCCCCC
EFYVHKPTLLRGNPAIVRRNLGSKKIRMVYAPSQDHGKQVQIEDVPEQQRNRFSLTDEEV
CEEEECCEEECCCHHHEEECCCCCEEEEEECCCCCCCCEEEECCCCHHHHCCCCCCHHHH
QGLAHQALLIEKHYGRPMDIEWAKDGHTGKLLIVQARPETVRSNEQTMERYQLNATSPVL
HHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCHHHHCCHHHHHHHHCCCCCCEE
VEGRAIGHRIGAGPVKVIHNISEMDRIEPGDVLVTDMTDPDWEPIMKKAAAIVTNRGGRT
EECHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCC
CHAAIIARELGIPAVVGCGNATDLLKEGQQVTVSCAEGDTGFVYSDILDFNVQSSEVTEL
HHHHHHHHHCCCCEEEECCCHHHHHHCCCEEEEEECCCCCCEEEHHHHCCCCCCCHHCCC
PDLPLKIMMNVGNPDRAFDFARLPNEGVGLARLEFIINRMIGVHPKALLEFDQQTPELQA
CCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHH
EIRTLMQGYDHPVEFYVGRLTEGIATLGAAFWPKRVIVRLSDFKSNEYANLVGGEKYEPH
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCHHCCCCCCCCCC
EENPMLGFRGAGRYVSDNFRDCFAMECDAVKRVRNEMGLTNVEIMVPFVRTVEQAEAVVA
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
ELARQGLKRGENGLKVIMMCEIPSNALLADQFLQHFDGFSIGSNDMTQLTLGLDRDSGVV
HHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHH
SELFDERNEAVKILLSMAIQAAKRQGKYVGICGQGPSDHEDFAEWLMDQGIDSLSLNPDT
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHH
VVQTWVNLSKRT
HHHHHHHHHCCC
>Mature Secondary Structure 
SNNGPDLRNVLWYNQLGMHDVDRVGGKNASLGEMITNLSDLGVAVPNGFATTAQAFNDF
CCCCCCHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHCCEECCCCCHHHHHHHHHH
LEQSGVNQRIYQLLDQTDVDDIAQLTKAGAQIRQWIIDTPFHAEFEREINLAYQQLADGE
HHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
PEASFAVRSSATAEDMPDASFAGQQETFLNVQGIDAVMVAIKHVFASLFNDRAISYRVHQ
CCCCEEECCCCCCCCCCCCCCCCCCHHEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEC
GYDHRGVALSAGVQRMVRSDLASSGVMFTIDTESGFDQVVFITSAFGLGEMVVQGAVNPD
CCCCCCEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCHHHHHHHCCCCCC
EFYVHKPTLLRGNPAIVRRNLGSKKIRMVYAPSQDHGKQVQIEDVPEQQRNRFSLTDEEV
CEEEECCEEECCCHHHEEECCCCCEEEEEECCCCCCCCEEEECCCCHHHHCCCCCCHHHH
QGLAHQALLIEKHYGRPMDIEWAKDGHTGKLLIVQARPETVRSNEQTMERYQLNATSPVL
HHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCHHHHCCHHHHHHHHCCCCCCEE
VEGRAIGHRIGAGPVKVIHNISEMDRIEPGDVLVTDMTDPDWEPIMKKAAAIVTNRGGRT
EECHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCC
CHAAIIARELGIPAVVGCGNATDLLKEGQQVTVSCAEGDTGFVYSDILDFNVQSSEVTEL
HHHHHHHHHCCCCEEEECCCHHHHHHCCCEEEEEECCCCCCEEEHHHHCCCCCCCHHCCC
PDLPLKIMMNVGNPDRAFDFARLPNEGVGLARLEFIINRMIGVHPKALLEFDQQTPELQA
CCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHH
EIRTLMQGYDHPVEFYVGRLTEGIATLGAAFWPKRVIVRLSDFKSNEYANLVGGEKYEPH
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCHHCCCCCCCCCC
EENPMLGFRGAGRYVSDNFRDCFAMECDAVKRVRNEMGLTNVEIMVPFVRTVEQAEAVVA
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
ELARQGLKRGENGLKVIMMCEIPSNALLADQFLQHFDGFSIGSNDMTQLTLGLDRDSGVV
HHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHH
SELFDERNEAVKILLSMAIQAAKRQGKYVGICGQGPSDHEDFAEWLMDQGIDSLSLNPDT
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHH
VVQTWVNLSKRT
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1310524; 9097039; 9278503 [H]