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The map label for this gene is pheS [H]

Identifier: 157370388

GI number: 157370388

Start: 2343281

End: 2344264

Strand: Direct

Name: pheS [H]

Synonym: Spro_2148

Alternate gene names: 157370388

Gene position: 2343281-2344264 (Clockwise)

Preceding gene: 157370387

Following gene: 157370389

Centisome position: 43.01

GC content: 54.27

Gene sequence:

>984_bases
ATGCCACATCTCGCAGAGCTGGTTGCCAATGCCAAGGCAGCCGTAGAAGATGCCCAGGATGTTGCCGCGTTAGATTTGGT
ACGCGTCGAATATTTAGGCAAGAAAGGCCATTTTACCTTACAGATGCAATCGCTGCGTGACGTGCCGGCAGAAGATCGCC
CGGCGGCCGGAGCGGTGATCAACCAGGCAAAGCAGGCGGTACAGGAAGCGCTGAACGCGCGTAAGAATGCGCTGGAATCT
GCTGCGTTGAATGAGCGTCTGGCGGCAGAAACCATCGACGTTTCTTTGCCGGGCCGTCGTATGGAAAACGGTGGGCTGCA
TCCGGTAACCCGTACCATCGACCGAATTGAAGCCTTCTTCGGCGAACTGGGCTTCTCCGTAGAGACCGGGCCTGAGATTG
AAGACGACTATCATAACTTCGACGCGCTGAATATTCCGGGTCACCACCCGGCGCGTGCCGATCACGATACCTTCTGGTTC
GATGCTACGCGTTTACTGCGTACCCAAACTTCTGGCGTGCAGATCCGCACCATGAAGGAGCAGCAGCCGCCAATCCGCAT
TATTGCGCCGGGTCGTGTTTACCGTAATGACTACGATCAGACGCATACTCCGATGTTCCATCAGATGGAAGGCCTGATTG
TCGACAAGGACATCAGTTTCACCAACCTGAAGGGCACGCTGCATGATTTCCTGAATAACTTCTTTGAAGAAGATTTGCAG
GTTCGTTTCCGTCCTTCTTACTTCCCGTTTACCGAACCTTCCGCTGAAGTGGATGTGATGGGCAAAAATGGCAAGTGGCT
GGAAGTTCTGGGCTGCGGCATGGTTCACCCGAACGTGCTGCGCAACGTGGGTATCGATCCGGAAGTTTACTCCGGCTTCG
CTTTCGGTATGGGTATGGAGCGTCTGACGATGCTGCGTTACGGCGTTACCGACCTGCGTGCGTTCTTCGAAAACGATCTG
CGCTTCCTCAAACAGTTTAAGTAA

Upstream 100 bases:

>100_bases
CGGGCTATAACTTAAAATGCTTTGGAGTTGAGCCAAAGGCGTGTTCGAATAATAGATAACAATTACTTAGAGCCATATCG
GCCAGAGGAAGAGGAAAGCA

Downstream 100 bases:

>100_bases
GGCGGGAATATTACATGAAATTCAGTGAACTCTGGTTGCGCGAGTGGGTAAACCCGGCCATCAGCAGCGAAGCATTATCC
GATCAAATTACCATGGCCGG

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPHLAELVANAKAAVEDAQDVAALDLVRVEYLGKKGHFTLQMQSLRDVPAEDRPAAGAVINQAKQAVQEALNARKNALES
AALNERLAAETIDVSLPGRRMENGGLHPVTRTIDRIEAFFGELGFSVETGPEIEDDYHNFDALNIPGHHPARADHDTFWF
DATRLLRTQTSGVQIRTMKEQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKDISFTNLKGTLHDFLNNFFEEDLQ
VRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRAFFENDL
RFLKQFK

Sequences:

>Translated_327_residues
MPHLAELVANAKAAVEDAQDVAALDLVRVEYLGKKGHFTLQMQSLRDVPAEDRPAAGAVINQAKQAVQEALNARKNALES
AALNERLAAETIDVSLPGRRMENGGLHPVTRTIDRIEAFFGELGFSVETGPEIEDDYHNFDALNIPGHHPARADHDTFWF
DATRLLRTQTSGVQIRTMKEQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKDISFTNLKGTLHDFLNNFFEEDLQ
VRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRAFFENDL
RFLKQFK
>Mature_326_residues
PHLAELVANAKAAVEDAQDVAALDLVRVEYLGKKGHFTLQMQSLRDVPAEDRPAAGAVINQAKQAVQEALNARKNALESA
ALNERLAAETIDVSLPGRRMENGGLHPVTRTIDRIEAFFGELGFSVETGPEIEDDYHNFDALNIPGHHPARADHDTFWFD
ATRLLRTQTSGVQIRTMKEQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKDISFTNLKGTLHDFLNNFFEEDLQV
RFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRAFFENDLR
FLKQFK

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=319, Percent_Identity=30.4075235109718, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI4758340, Length=259, Percent_Identity=32.8185328185328, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1788007, Length=327, Percent_Identity=90.2140672782875, Blast_Score=622, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI32566635, Length=242, Percent_Identity=33.0578512396694, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17508957, Length=260, Percent_Identity=30.3846153846154, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32563657, Length=260, Percent_Identity=30.3846153846154, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6321087, Length=267, Percent_Identity=29.2134831460674, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325304, Length=90, Percent_Identity=41.1111111111111, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18858079, Length=258, Percent_Identity=30.6201550387597, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17137424, Length=279, Percent_Identity=29.7491039426523, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 36918; Mature: 36787

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHLAELVANAKAAVEDAQDVAALDLVRVEYLGKKGHFTLQMQSLRDVPAEDRPAAGAVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCHHHHH
NQAKQAVQEALNARKNALESAALNERLAAETIDVSLPGRRMENGGLHPVTRTIDRIEAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
GELGFSVETGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKE
HHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECC
QQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKDISFTNLKGTLHDFLNNFFEEDLQ
CCCCEEEEECCHHHCCCCCCCCCCHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHE
VRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGME
EEECCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHCCCCHHHHCCHHHHCCHH
RLTMLRYGVTDLRAFFENDLRFLKQFK
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PHLAELVANAKAAVEDAQDVAALDLVRVEYLGKKGHFTLQMQSLRDVPAEDRPAAGAVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCHHHHH
NQAKQAVQEALNARKNALESAALNERLAAETIDVSLPGRRMENGGLHPVTRTIDRIEAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
GELGFSVETGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKE
HHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECC
QQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKDISFTNLKGTLHDFLNNFFEEDLQ
CCCCEEEEECCHHHCCCCCCCCCCHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHE
VRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGME
EEECCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHCCCCHHHHCCHHHHCCHH
RLTMLRYGVTDLRAFFENDLRFLKQFK
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA