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The map label for this gene is xylB [H]

Identifier: 157370198

GI number: 157370198

Start: 2137153

End: 2138250

Strand: Direct

Name: xylB [H]

Synonym: Spro_1956

Alternate gene names: 157370198

Gene position: 2137153-2138250 (Clockwise)

Preceding gene: 157370196

Following gene: 157370199

Centisome position: 39.22

GC content: 59.38

Gene sequence:

>1098_bases
ATGGAAATAACAGCCGCAGTCAGTGAAAAAGCGACGGAGGGATTCTCCCTCAAACAGTTACAGCTTGGAGAACCCCGCGC
CGATGAGGTGTTGGCAAAACTGGTCGCGACCGGCCTGTGCCATACCGATATCGCCGCGCACAAAGGCGTTATATCGATGC
CTGCGCCGGTGGTGCTCGGCCATGAAGGCGCCGGGGTCGTAGTGCGGGTCGGGGCCGGGGTCAGTAAGGTGGCGCCCGGC
GATCATGTGGTGCTGTCGCTGGCCTCATGCGGCGTCTGCGACAAGTGTAGCATCGGCATGCCGACCTATTGCCGTCAACA
TGTGCCATTGAACTGGCTGGCGCAGCGCACCGACGGTTCGGTCAGCCTGCATGATGAAAATGGCGATGTGCACAGCCATT
TCTTCGGTCAGTCCTCTTTTGCGCAGTATGCCGTGGTCAATGTCAGCAGCATTGTCCCTGTCGATAAGGCGATCCCGTTG
GAATACCTTGGGCCATTGGCCTGCGGACTGATGACCGGCGCGGGCGCAGTGATGAACACTCTGCGGCCGCATGCGGGTTC
TACGCTGGTGGTCTTTGGTCTTGGCGCGGTGGGCCTGGCGGCGGTGATGGCAGCCCGGGTGGTGGGTTGCGGCCACATCG
TCGCGGTGGATATCAAAGAGAACCGTCTGGCGTTAGCCAAAGAGTTGGGCGCTACAGAGGTGATCAACCCGAAAACGGCG
AATGTGGATGAAGTGCTTAATCAACTGACCGAGGGACGCGGTGCGGACTACAGCGTTGAAGCCGCCGGGAACGCGGGCGT
CATGGCCGATGCGGTGCGGGTGTTGGCGGAAAATGGCAAATGCGTACTGACCGGCGTGGTACCGGAGGGCGAATCTTTGC
CGCTCGACATTATGCACTTTATCCGCGGCCGCACGGTGCAGGGTTCGATCATGGGCGATGCGGCACCGGCGATGTTTATC
CCGATGCTGGCGCAGCTATTCCAGCAAGGGCGGTTCCCGATCGATCGCCTTATCCGTTTTTATGCCATGAATGAGATCAA
CCAGGCGATGGCGGACTCACAATCCGGTGAAACCATTAAAGCCGTTATTCGTATGTAA

Upstream 100 bases:

>100_bases
TTGAGAACAGTGAGTCAGAGTATGACATCTTTTTACACCCAATAACCCATCTTATACTGCCCACATCGAAACAACGGCAC
CAGGGCCAGTGGGAGATGAC

Downstream 100 bases:

>100_bases
CCCTCAATAAGGTCAATAACATGAAACGACTCTTTTCAGCGGCCCTGCTGGGGCTGATGGGCGCGGCTGCGTCCGCGCAG
GCCAACGATCATATTATCGA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MEITAAVSEKATEGFSLKQLQLGEPRADEVLAKLVATGLCHTDIAAHKGVISMPAPVVLGHEGAGVVVRVGAGVSKVAPG
DHVVLSLASCGVCDKCSIGMPTYCRQHVPLNWLAQRTDGSVSLHDENGDVHSHFFGQSSFAQYAVVNVSSIVPVDKAIPL
EYLGPLACGLMTGAGAVMNTLRPHAGSTLVVFGLGAVGLAAVMAARVVGCGHIVAVDIKENRLALAKELGATEVINPKTA
NVDEVLNQLTEGRGADYSVEAAGNAGVMADAVRVLAENGKCVLTGVVPEGESLPLDIMHFIRGRTVQGSIMGDAAPAMFI
PMLAQLFQQGRFPIDRLIRFYAMNEINQAMADSQSGETIKAVIRM

Sequences:

>Translated_365_residues
MEITAAVSEKATEGFSLKQLQLGEPRADEVLAKLVATGLCHTDIAAHKGVISMPAPVVLGHEGAGVVVRVGAGVSKVAPG
DHVVLSLASCGVCDKCSIGMPTYCRQHVPLNWLAQRTDGSVSLHDENGDVHSHFFGQSSFAQYAVVNVSSIVPVDKAIPL
EYLGPLACGLMTGAGAVMNTLRPHAGSTLVVFGLGAVGLAAVMAARVVGCGHIVAVDIKENRLALAKELGATEVINPKTA
NVDEVLNQLTEGRGADYSVEAAGNAGVMADAVRVLAENGKCVLTGVVPEGESLPLDIMHFIRGRTVQGSIMGDAAPAMFI
PMLAQLFQQGRFPIDRLIRFYAMNEINQAMADSQSGETIKAVIRM
>Mature_365_residues
MEITAAVSEKATEGFSLKQLQLGEPRADEVLAKLVATGLCHTDIAAHKGVISMPAPVVLGHEGAGVVVRVGAGVSKVAPG
DHVVLSLASCGVCDKCSIGMPTYCRQHVPLNWLAQRTDGSVSLHDENGDVHSHFFGQSSFAQYAVVNVSSIVPVDKAIPL
EYLGPLACGLMTGAGAVMNTLRPHAGSTLVVFGLGAVGLAAVMAARVVGCGHIVAVDIKENRLALAKELGATEVINPKTA
NVDEVLNQLTEGRGADYSVEAAGNAGVMADAVRVLAENGKCVLTGVVPEGESLPLDIMHFIRGRTVQGSIMGDAAPAMFI
PMLAQLFQQGRFPIDRLIRFYAMNEINQAMADSQSGETIKAVIRM

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501929, Length=368, Percent_Identity=36.6847826086957, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI34577061, Length=370, Percent_Identity=37.2972972972973, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=36.4130434782609, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI156523966, Length=370, Percent_Identity=34.8648648648649, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI4501939, Length=362, Percent_Identity=35.3591160220994, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI71565154, Length=371, Percent_Identity=35.0404312668464, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI71743840, Length=368, Percent_Identity=33.695652173913, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI262073058, Length=368, Percent_Identity=33.695652173913, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI71565152, Length=372, Percent_Identity=31.989247311828, Blast_Score=190, Evalue=2e-48,
Organism=Escherichia coli, GI1786552, Length=372, Percent_Identity=34.1397849462366, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788073, Length=350, Percent_Identity=28, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082125, Length=364, Percent_Identity=25.5494505494505, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788407, Length=295, Percent_Identity=26.1016949152542, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790045, Length=365, Percent_Identity=25.7534246575342, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081918, Length=304, Percent_Identity=29.9342105263158, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787863, Length=327, Percent_Identity=25.6880733944954, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI226510992, Length=363, Percent_Identity=25.8953168044077, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786518, Length=322, Percent_Identity=26.3975155279503, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786825, Length=261, Percent_Identity=25.2873563218391, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790718, Length=276, Percent_Identity=24.6376811594203, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25146526, Length=371, Percent_Identity=35.8490566037736, Blast_Score=200, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI71997431, Length=373, Percent_Identity=35.656836461126, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17565904, Length=343, Percent_Identity=35.2769679300292, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17562876, Length=365, Percent_Identity=24.3835616438356, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562878, Length=362, Percent_Identity=26.5193370165746, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17562584, Length=366, Percent_Identity=25.4098360655738, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988145, Length=303, Percent_Identity=24.7524752475248, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562582, Length=311, Percent_Identity=25.4019292604502, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320033, Length=375, Percent_Identity=33.0666666666667, Blast_Score=202, Evalue=9e-53,
Organism=Saccharomyces cerevisiae, GI6319258, Length=272, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=349, Percent_Identity=25.214899713467, Blast_Score=83, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323099, Length=283, Percent_Identity=27.9151943462898, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=308, Percent_Identity=25.6493506493506, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=346, Percent_Identity=25.1445086705202, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=354, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=370, Percent_Identity=23.2432432432432, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17737895, Length=370, Percent_Identity=34.8648648648649, Blast_Score=201, Evalue=9e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 38143; Mature: 38143

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEITAAVSEKATEGFSLKQLQLGEPRADEVLAKLVATGLCHTDIAAHKGVISMPAPVVLG
CCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHCCCEEECCCCEEEE
HEGAGVVVRVGAGVSKVAPGDHVVLSLASCGVCDKCSIGMPTYCRQHVPLNWLAQRTDGS
CCCCCEEEEECCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCHHHHCCCCHHHHHHCCCCC
VSLHDENGDVHSHFFGQSSFAQYAVVNVSSIVPVDKAIPLEYLGPLACGLMTGAGAVMNT
EEEECCCCCCHHHHCCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
LRPHAGSTLVVFGLGAVGLAAVMAARVVGCGHIVAVDIKENRLALAKELGATEVINPKTA
CCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCCCCCCCCCC
NVDEVLNQLTEGRGADYSVEAAGNAGVMADAVRVLAENGKCVLTGVVPEGESLPLDIMHF
CHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
IRGRTVQGSIMGDAAPAMFIPMLAQLFQQGRFPIDRLIRFYAMNEINQAMADSQSGETIK
HCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
AVIRM
HHHCC
>Mature Secondary Structure
MEITAAVSEKATEGFSLKQLQLGEPRADEVLAKLVATGLCHTDIAAHKGVISMPAPVVLG
CCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHCCCEEECCCCEEEE
HEGAGVVVRVGAGVSKVAPGDHVVLSLASCGVCDKCSIGMPTYCRQHVPLNWLAQRTDGS
CCCCCEEEEECCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCHHHHCCCCHHHHHHCCCCC
VSLHDENGDVHSHFFGQSSFAQYAVVNVSSIVPVDKAIPLEYLGPLACGLMTGAGAVMNT
EEEECCCCCCHHHHCCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
LRPHAGSTLVVFGLGAVGLAAVMAARVVGCGHIVAVDIKENRLALAKELGATEVINPKTA
CCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCCCCCCCCCC
NVDEVLNQLTEGRGADYSVEAAGNAGVMADAVRVLAENGKCVLTGVVPEGESLPLDIMHF
CHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
IRGRTVQGSIMGDAAPAMFIPMLAQLFQQGRFPIDRLIRFYAMNEINQAMADSQSGETIK
HCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
AVIRM
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]