| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is ykvO [H]
Identifier: 157370159
GI number: 157370159
Start: 2100822
End: 2101568
Strand: Reverse
Name: ykvO [H]
Synonym: Spro_1917
Alternate gene names: 157370159
Gene position: 2101568-2100822 (Counterclockwise)
Preceding gene: 157370161
Following gene: 157370157
Centisome position: 38.57
GC content: 59.71
Gene sequence:
>747_bases ATGTCACGACTTAAAGGTAAATATGCGTTGATCACCGGCGGCACCAGCGGTATTGGTCTGGAAACTGCGCGTCAGTTTAT TGCCGAAGGTGCCACCGTGGCGATCACCGGTCGCAGCCAAAGTGGCCTCGACGAGGCGGGGGCAGCTCTGGGCAAGGTTC TGTTGTTGCGCAGCGATGCCGGGGATATTGCTGATCAGCGTAGTTTGGCACAGCAGTTGGCCAGCCATTGGCCGCGCCTC GATGTGTTGTACATCAACGCCGGCGACGTCACCCACCACCCGTTGCAGGAATGGGATGAGCAGAGCTATCAGCGGCTGAT GGATATTAATCTCAAGGGGCCGTTCTTTCTGATCCAGTCATTGTTGCCACTGTTGGCCAATCCGGCGTCGATTATTTTGT GTGGCTCGGTCAGCGCACATATTGGCCTGCCGTTAAGCAACGTTTACGCCGCCAGCAAAGCCGGCCTGCTGTCGCTGGCC AGAACGCTGTCTGGTGAATTGCATCCGCGCGGGATCCGGGTTAACGGCCTCAGCCCCGGCCCGACAGAAACCCCGGCGCT GGGCAAGCTCGGGTTGAAGGATGCCGATGAGCAAGCACTGCGCGACGAGATCCGCGCCCTGGTGCCGATCGGCCGCATGG GCACGGCGCTGGAATTAGCCAAGGCGGCGGTGTTTTTGGCGTCTGACGAGTCCGCCTTTATGGTCGGCAGTGAGTTGTTG ATCGACGGCGGCGTGGGGAATTTGTAG
Upstream 100 bases:
>100_bases TTTCATCCCACCTTGTCCCTTAGTATCCAAAAGGTGCCTACTATGCAAAAGGTACTATAGCGCAAATAATGCTTGCATCG ACAACAAACGGGAGTGGGCT
Downstream 100 bases:
>100_bases CAGTGATGGTTTGGACGTCAAGCCGTGACAGCAACGACTGCACGGCTTGTCAGTTAACCCAGACCGGGGATAGCAACGCC GAAAGTCTGCAGCAGCAACA
Product: short chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 248; Mature: 247
Protein sequence:
>248_residues MSRLKGKYALITGGTSGIGLETARQFIAEGATVAITGRSQSGLDEAGAALGKVLLLRSDAGDIADQRSLAQQLASHWPRL DVLYINAGDVTHHPLQEWDEQSYQRLMDINLKGPFFLIQSLLPLLANPASIILCGSVSAHIGLPLSNVYAASKAGLLSLA RTLSGELHPRGIRVNGLSPGPTETPALGKLGLKDADEQALRDEIRALVPIGRMGTALELAKAAVFLASDESAFMVGSELL IDGGVGNL
Sequences:
>Translated_248_residues MSRLKGKYALITGGTSGIGLETARQFIAEGATVAITGRSQSGLDEAGAALGKVLLLRSDAGDIADQRSLAQQLASHWPRL DVLYINAGDVTHHPLQEWDEQSYQRLMDINLKGPFFLIQSLLPLLANPASIILCGSVSAHIGLPLSNVYAASKAGLLSLA RTLSGELHPRGIRVNGLSPGPTETPALGKLGLKDADEQALRDEIRALVPIGRMGTALELAKAAVFLASDESAFMVGSELL IDGGVGNL >Mature_247_residues SRLKGKYALITGGTSGIGLETARQFIAEGATVAITGRSQSGLDEAGAALGKVLLLRSDAGDIADQRSLAQQLASHWPRLD VLYINAGDVTHHPLQEWDEQSYQRLMDINLKGPFFLIQSLLPLLANPASIILCGSVSAHIGLPLSNVYAASKAGLLSLAR TLSGELHPRGIRVNGLSPGPTETPALGKLGLKDADEQALRDEIRALVPIGRMGTALELAKAAVFLASDESAFMVGSELLI DGGVGNL
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI66933014, Length=247, Percent_Identity=32.3886639676113, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=29.0322580645161, Blast_Score=107, Evalue=9e-24, Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=32.7433628318584, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.1204819277108, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=34.7368421052632, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=28.1746031746032, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=29.3388429752066, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=23.921568627451, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=29.9212598425197, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=27.2, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=30.939226519337, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=27.3076923076923, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=27.4611398963731, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=27.2251308900524, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI223718074, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7657478, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI31542939, Length=222, Percent_Identity=26.5765765765766, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI109715829, Length=251, Percent_Identity=25.4980079681275, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=34.412955465587, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=30.1587301587302, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=32.9365079365079, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=30.6451612903226, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=30.8, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=27.2, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=28.515625, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=30.0813008130081, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787820, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=27.3092369477912, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=30.241935483871, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1787545, Length=258, Percent_Identity=28.6821705426357, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1787526, Length=212, Percent_Identity=32.0754716981132, Blast_Score=76, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=31.4393939393939, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=31.6205533596838, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=29.7709923664122, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=30.1158301158301, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=30.8270676691729, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=29.7297297297297, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=29.7619047619048, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=31.4176245210728, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=31.0344827586207, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=29.811320754717, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=27.2357723577236, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.5454545454545, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=29.0322580645161, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=26.7206477732794, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=29.0322580645161, Blast_Score=94, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=28.735632183908, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=29.1187739463602, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=29.4354838709677, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=30.9160305343511, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=30.2681992337165, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=29.5019157088123, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=29.3893129770992, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=30.3149606299213, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=29.2490118577075, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=31.25, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=27.8625954198473, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=29.7709923664122, Blast_Score=77, Evalue=9e-15, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=27.843137254902, Blast_Score=94, Evalue=2e-20, Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=32.03125, Blast_Score=130, Evalue=8e-31, Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=32.2448979591837, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=31.4741035856574, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=32.9218106995885, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=31.0756972111554, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=28.4, Blast_Score=98, Evalue=4e-21, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=29.4354838709677, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=30, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=27.34375, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24647946, Length=202, Percent_Identity=28.7128712871287, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI45553409, Length=200, Percent_Identity=29, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24647948, Length=200, Percent_Identity=29, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331218, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24665243, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=28.6458333333333, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 26025; Mature: 25894
Theoretical pI: Translated: 6.02; Mature: 6.02
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSRLKGKYALITGGTSGIGLETARQFIAEGATVAITGRSQSGLDEAGAALGKVLLLRSDA CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHEEEEECCC GDIADQRSLAQQLASHWPRLDVLYINAGDVTHHPLQEWDEQSYQRLMDINLKGPFFLIQS CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH LLPLLANPASIILCGSVSAHIGLPLSNVYAASKAGLLSLARTLSGELHPRGIRVNGLSPG HHHHHCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCC PTETPALGKLGLKDADEQALRDEIRALVPIGRMGTALELAKAAVFLASDESAFMVGSELL CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEECCCCEEEECCEEE IDGGVGNL EECCCCCC >Mature Secondary Structure SRLKGKYALITGGTSGIGLETARQFIAEGATVAITGRSQSGLDEAGAALGKVLLLRSDA CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHEEEEECCC GDIADQRSLAQQLASHWPRLDVLYINAGDVTHHPLQEWDEQSYQRLMDINLKGPFFLIQS CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH LLPLLANPASIILCGSVSAHIGLPLSNVYAASKAGLLSLARTLSGELHPRGIRVNGLSPG HHHHHCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCC PTETPALGKLGLKDADEQALRDEIRALVPIGRMGTALELAKAAVFLASDESAFMVGSELL CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEECCCCEEEECCEEE IDGGVGNL EECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]