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The map label for this gene is oprF [H]

Identifier: 157370029

GI number: 157370029

Start: 1963068

End: 1964777

Strand: Direct

Name: oprF [H]

Synonym: Spro_1787

Alternate gene names: 157370029

Gene position: 1963068-1964777 (Clockwise)

Preceding gene: 157370028

Following gene: 157370030

Centisome position: 36.03

GC content: 60.82

Gene sequence:

>1710_bases
ATGAGTTCTGCACAACAGCGTGGGCTTGCGCTGTGGGCCGTCCTGCTGAGTGCAGTGGTCTGCCTGGTTTTTCTGCCTGC
ATCCCGGCTGGTGTCCGTTCTTGTTTTTCTGGTTGTTCTGGGGCTGATTGCGGCGTCCTGGTACGTCGCCAGTCGTCGTG
TTCAGCACGACGTCACCCTGAGTCTGCAAGCTCTCCCGGAGGCGGCATATCGCCAGCCGGTGGTGTTGGTCTGTGGCGAT
CTGTCGTTGGCCTGGCCGGAACCGTTACCGGTGCTGACCGTCACTCAGGGGTGTTGGATCCGGGTGGAAGACCACCAGAG
CCTGGAGCAGGTGGCCCGACAGGTACTGTGGCAGCGCCCTGACTGGGGGCGTCAGCTGTCGGTGATGGTCAGTGTCTGCC
CGCAGAAGCACGCTGACTGCGAAGCACTGACCAGCCGCCTGCTGACTCTGCGCTGGCAAATCAGCCGGTTGCGTAAGGAT
ACCGGGCATTCCGTGCCGCTGGTTTTGAATGGTCAGGTCGGCAGCGCGATGACGAATGAGCTGCTCTGGCAGGCGGCGAT
CCCGGAAGAAGGGGTGAGGGTCTGGCGGGAGTCTTCAGCACCGAGTTCTATCGCCGCATGGGTCACTACCGGCGGAACGC
CAGCAATGCAGCAACAGGTGCTGATGAACAGCCTGATGAGCTGGTTCCATCAGCACGTCAATGCCGTCTTTTTGGATGAA
AACCCCGATGTTCAGGCCATTGCACCTACAGCGGTGCTGTGGGGAATGGGGCCTATCCTTGCCGGGAGCCTGGCGTCATC
GGCCTGGACGGCGTGGTTGTCGCGTCACACCGCCATGCAGCAGGTGACGGGTTGGCAGCCGGTGGGGACGGACAGCTCGG
TGATATCACCATTCCCGGATTTCGTCCTGCCGCTGCTGCCGGAAGGGCGAGGATTAACCTCGCGGGGGCGTGCCTGGCGC
TGTGCACTCGGGATCTTCACTCTGGCGGCCATTGCGGCGCTGCTCAGCAGTGGCTGGAACAATCGCCAGCTGCTGCACCG
CGTAAGCTTCGATATTGCCCGGTATGACCATATCCCGATAGATGATTACGGTCCGAAAACCGATGCCGTCGCGGTCCTGC
GAGAGGATGCCGCGCAGCTGGATGACCAGGCGCGTAATGGCGTACCGACCCGGATGAGCCTCGGCCTGTATCAGGGCGAG
CGTCTGCGTATGCCGCTGCTGGATGCGATCCGCTCGTATGTTCCGCCGCCACTGCCGTCCAAACCTCAACCGAAGCCTGC
CCCGAAAATTGTGCGGCTCGACAGCATGTCGCTGTTCGATTCCGGTAAATACGCGCTGAAGGCGGGCTCCACCAAAATGC
TCATTAACTCCCTTGTGGGCATCAAAGCCAAGCCGGGCTGGCTGATTGTGGTGGCAGGCCACACGGATAACACCGGCAAT
CCAGCACTCAATCAGACGCTTTCCCAGAAACGTGCCGCAGCAGTACGTGACTGGATGCGTGATACCGGCGATGTGCCGGA
AAGTTGTTTTGCGGTGCAGGGCTATGGCGAAAGTCGGCCGGTTGCCACCAATGACACTCCGGAAGGCCGTGCGCTTAACC
GGCGTGTCGAAATCAGTCTGGTACCTCAGGCAGATGCCTGCCGGATACCGGGCAACACCCCGACGTCATCACTGGATGGT
GACGTATCAAAAAACGAAATGGAGAAGTAA

Upstream 100 bases:

>100_bases
TGCGTATTGGCCTGAGCGTGATTGTGGTCGCCGCCCTGTGGTGGGGGCTGAACCACTGGCTCGATCAGATGCTGTTGACC
CTGTTGCCGGGAGCCGTGAA

Downstream 100 bases:

>100_bases
ACCATGGCAATTCCAGTTTATCTTTGGCTGAAAGACGACGGCGGCGCGGACATTAAAGGATCTGTAGATGTTAAAGACCG
CGAAGGCAGCATTGAAGTGG

Product: OmpA/MotB domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSSAQQRGLALWAVLLSAVVCLVFLPASRLVSVLVFLVVLGLIAASWYVASRRVQHDVTLSLQALPEAAYRQPVVLVCGD
LSLAWPEPLPVLTVTQGCWIRVEDHQSLEQVARQVLWQRPDWGRQLSVMVSVCPQKHADCEALTSRLLTLRWQISRLRKD
TGHSVPLVLNGQVGSAMTNELLWQAAIPEEGVRVWRESSAPSSIAAWVTTGGTPAMQQQVLMNSLMSWFHQHVNAVFLDE
NPDVQAIAPTAVLWGMGPILAGSLASSAWTAWLSRHTAMQQVTGWQPVGTDSSVISPFPDFVLPLLPEGRGLTSRGRAWR
CALGIFTLAAIAALLSSGWNNRQLLHRVSFDIARYDHIPIDDYGPKTDAVAVLREDAAQLDDQARNGVPTRMSLGLYQGE
RLRMPLLDAIRSYVPPPLPSKPQPKPAPKIVRLDSMSLFDSGKYALKAGSTKMLINSLVGIKAKPGWLIVVAGHTDNTGN
PALNQTLSQKRAAAVRDWMRDTGDVPESCFAVQGYGESRPVATNDTPEGRALNRRVEISLVPQADACRIPGNTPTSSLDG
DVSKNEMEK

Sequences:

>Translated_569_residues
MSSAQQRGLALWAVLLSAVVCLVFLPASRLVSVLVFLVVLGLIAASWYVASRRVQHDVTLSLQALPEAAYRQPVVLVCGD
LSLAWPEPLPVLTVTQGCWIRVEDHQSLEQVARQVLWQRPDWGRQLSVMVSVCPQKHADCEALTSRLLTLRWQISRLRKD
TGHSVPLVLNGQVGSAMTNELLWQAAIPEEGVRVWRESSAPSSIAAWVTTGGTPAMQQQVLMNSLMSWFHQHVNAVFLDE
NPDVQAIAPTAVLWGMGPILAGSLASSAWTAWLSRHTAMQQVTGWQPVGTDSSVISPFPDFVLPLLPEGRGLTSRGRAWR
CALGIFTLAAIAALLSSGWNNRQLLHRVSFDIARYDHIPIDDYGPKTDAVAVLREDAAQLDDQARNGVPTRMSLGLYQGE
RLRMPLLDAIRSYVPPPLPSKPQPKPAPKIVRLDSMSLFDSGKYALKAGSTKMLINSLVGIKAKPGWLIVVAGHTDNTGN
PALNQTLSQKRAAAVRDWMRDTGDVPESCFAVQGYGESRPVATNDTPEGRALNRRVEISLVPQADACRIPGNTPTSSLDG
DVSKNEMEK
>Mature_568_residues
SSAQQRGLALWAVLLSAVVCLVFLPASRLVSVLVFLVVLGLIAASWYVASRRVQHDVTLSLQALPEAAYRQPVVLVCGDL
SLAWPEPLPVLTVTQGCWIRVEDHQSLEQVARQVLWQRPDWGRQLSVMVSVCPQKHADCEALTSRLLTLRWQISRLRKDT
GHSVPLVLNGQVGSAMTNELLWQAAIPEEGVRVWRESSAPSSIAAWVTTGGTPAMQQQVLMNSLMSWFHQHVNAVFLDEN
PDVQAIAPTAVLWGMGPILAGSLASSAWTAWLSRHTAMQQVTGWQPVGTDSSVISPFPDFVLPLLPEGRGLTSRGRAWRC
ALGIFTLAAIAALLSSGWNNRQLLHRVSFDIARYDHIPIDDYGPKTDAVAVLREDAAQLDDQARNGVPTRMSLGLYQGER
LRMPLLDAIRSYVPPPLPSKPQPKPAPKIVRLDSMSLFDSGKYALKAGSTKMLINSLVGIKAKPGWLIVVAGHTDNTGNP
ALNQTLSQKRAAAVRDWMRDTGDVPESCFAVQGYGESRPVATNDTPEGRALNRRVEISLVPQADACRIPGNTPTSSLDGD
VSKNEMEK

Specific function: Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=104, Percent_Identity=41.3461538461538, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788957, Length=66, Percent_Identity=46.969696969697, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006690
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 62140; Mature: 62009

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAQQRGLALWAVLLSAVVCLVFLPASRLVSVLVFLVVLGLIAASWYVASRRVQHDVTL
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
SLQALPEAAYRQPVVLVCGDLSLAWPEPLPVLTVTQGCWIRVEDHQSLEQVARQVLWQRP
EHHHCCHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHCCC
DWGRQLSVMVSVCPQKHADCEALTSRLLTLRWQISRLRKDTGHSVPLVLNGQVGSAMTNE
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
LLWQAAIPEEGVRVWRESSAPSSIAAWVTTGGTPAMQQQVLMNSLMSWFHQHVNAVFLDE
HHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEECC
NPDVQAIAPTAVLWGMGPILAGSLASSAWTAWLSRHTAMQQVTGWQPVGTDSSVISPFPD
CCCCEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
FVLPLLPEGRGLTSRGRAWRCALGIFTLAAIAALLSSGWNNRQLLHRVSFDIARYDHIPI
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC
DDYGPKTDAVAVLREDAAQLDDQARNGVPTRMSLGLYQGERLRMPLLDAIRSYVPPPLPS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCC
KPQPKPAPKIVRLDSMSLFDSGKYALKAGSTKMLINSLVGIKAKPGWLIVVAGHTDNTGN
CCCCCCCCCEEEECCCHHHCCCCEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
PALNQTLSQKRAAAVRDWMRDTGDVPESCFAVQGYGESRPVATNDTPEGRALNRRVEISL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCCCCCCCCEEEEEE
VPQADACRIPGNTPTSSLDGDVSKNEMEK
CCCCCCCCCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
SSAQQRGLALWAVLLSAVVCLVFLPASRLVSVLVFLVVLGLIAASWYVASRRVQHDVTL
CCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
SLQALPEAAYRQPVVLVCGDLSLAWPEPLPVLTVTQGCWIRVEDHQSLEQVARQVLWQRP
EHHHCCHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHCCC
DWGRQLSVMVSVCPQKHADCEALTSRLLTLRWQISRLRKDTGHSVPLVLNGQVGSAMTNE
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
LLWQAAIPEEGVRVWRESSAPSSIAAWVTTGGTPAMQQQVLMNSLMSWFHQHVNAVFLDE
HHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEECC
NPDVQAIAPTAVLWGMGPILAGSLASSAWTAWLSRHTAMQQVTGWQPVGTDSSVISPFPD
CCCCEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
FVLPLLPEGRGLTSRGRAWRCALGIFTLAAIAALLSSGWNNRQLLHRVSFDIARYDHIPI
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC
DDYGPKTDAVAVLREDAAQLDDQARNGVPTRMSLGLYQGERLRMPLLDAIRSYVPPPLPS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCC
KPQPKPAPKIVRLDSMSLFDSGKYALKAGSTKMLINSLVGIKAKPGWLIVVAGHTDNTGN
CCCCCCCCCEEEECCCHHHCCCCEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
PALNQTLSQKRAAAVRDWMRDTGDVPESCFAVQGYGESRPVATNDTPEGRALNRRVEISL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCCCCCCCCEEEEEE
VPQADACRIPGNTPTSSLDGDVSKNEMEK
CCCCCCCCCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2447060; 10984043 [H]