Click here to switch to the map view.

The map label for this gene is ompA [H]

Identifier: 157369997

GI number: 157369997

Start: 1933209

End: 1934285

Strand: Reverse

Name: ompA [H]

Synonym: Spro_1754

Alternate gene names: 157369997

Gene position: 1934285-1933209 (Counterclockwise)

Preceding gene: 157369998

Following gene: 157369995

Centisome position: 35.5

GC content: 52.0

Gene sequence:

>1077_bases
ATGAAAAAGACAGCTATCGCATTAGCAGTGGCACTGGCTGGTTTCGCTACCGTAGCGCAAGCCGCCCCAAAAGATAATAC
CTGGTACACTGGTGCTAAACTGGGCTGGTCCCAGTACCATGACACTGGTTTCTACGGCAACGGTTACCAGAATGGTATCG
GCAATGGTCCGACCCATAAAGATCAACTGGGTGCTGGCGCGTTCCTGGGTTACCAGGCGAACCAATACCTGGGCTTCGAG
CTGGGCTATGACTGGCTTGGCCGTATGCCTTACAAAGGCAGCGTGAACAACGGTGCTTTCAAAGCGCAGGGCGTTCAACT
GGCCGCTAAACTGAGCTACCCAATCATGGACGATCTGGACATCTACACTCGTCTGGGCGGCATGGTATGGCGTGCAGATT
CCAAAGCTAACTACGGTAACGGCACTCGTCTGAGCGATCACGACACTGGCGTTTCTCCGTTGGCAGCAGTTGGTGTTGAA
TACGCACTGACCAAAAACTGGGCTACCCGCCTGGACTACCAATTCGTTAGCAACATCGGTGATGCAGGTACTGTCGGCGC
ACGTCCAGACAACACCATGCTGAGCCTGGGTGTTTCTTACCGTTTCGGTCAGGATGATGTTGTTGCTCCAGCACCAGCTC
CAGCTCCGGCTCCAGTTGTTGAAACCAAGCGTTTCACTCTGAAGTCTGACGTGCTGTTCAACTTCAACAAATCTACCCTG
AAAGCAGAAGGCCAACAGGCTCTTGACCAGCTGTACACTCAGCTGAGCGCAATGGATCCTAAAGATGGTTCTGCTGTAGT
TCTGGGTTACACCGACGCCGTTGGTTCTGACCAGTACAACCAGAAACTGTCTGAAAAACGCGCACAAAGCGTTGTTGATT
ACCTGGTATCTAAAGGTATCCCTTCAGAAAAAATCTCTGCACGTGGTATGGGCGAAGCTGATTCCGTCACTGGCAACACC
TGTGGCTACAAAGCTGGTCGTGCTACTAAAGCACAGATCGCTTGCCTGGCACCAGATCGTCGCGTAGAGATCGAAGTTAA
AGGTATCAAAGACGTTGTAACTCAGCCACAAGGCTAA

Upstream 100 bases:

>100_bases
GAGTAACAAACGAGGGCTCAAACCTTGGCGAAGGAATTTAACCAAGGGCTTAAAACAGCTTTAAAGCTCATTGCCTATTT
GGATGATAACGAGGCGCAAA

Downstream 100 bases:

>100_bases
GCTACCACTCTTAGTAAAAAACCCCGCAATGCGGGGTTTTTTTTCGACTAAATCAAATGGTGTAAGCAACAAAGAGCCAC
TTCCCTTACAGGTAACTGGC

Product: outer membrane protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKKTAIALAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFYGNGYQNGIGNGPTHKDQLGAGAFLGYQANQYLGFE
LGYDWLGRMPYKGSVNNGAFKAQGVQLAAKLSYPIMDDLDIYTRLGGMVWRADSKANYGNGTRLSDHDTGVSPLAAVGVE
YALTKNWATRLDYQFVSNIGDAGTVGARPDNTMLSLGVSYRFGQDDVVAPAPAPAPAPVVETKRFTLKSDVLFNFNKSTL
KAEGQQALDQLYTQLSAMDPKDGSAVVLGYTDAVGSDQYNQKLSEKRAQSVVDYLVSKGIPSEKISARGMGEADSVTGNT
CGYKAGRATKAQIACLAPDRRVEIEVKGIKDVVTQPQG

Sequences:

>Translated_358_residues
MKKTAIALAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFYGNGYQNGIGNGPTHKDQLGAGAFLGYQANQYLGFE
LGYDWLGRMPYKGSVNNGAFKAQGVQLAAKLSYPIMDDLDIYTRLGGMVWRADSKANYGNGTRLSDHDTGVSPLAAVGVE
YALTKNWATRLDYQFVSNIGDAGTVGARPDNTMLSLGVSYRFGQDDVVAPAPAPAPAPVVETKRFTLKSDVLFNFNKSTL
KAEGQQALDQLYTQLSAMDPKDGSAVVLGYTDAVGSDQYNQKLSEKRAQSVVDYLVSKGIPSEKISARGMGEADSVTGNT
CGYKAGRATKAQIACLAPDRRVEIEVKGIKDVVTQPQG
>Mature_358_residues
MKKTAIALAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFYGNGYQNGIGNGPTHKDQLGAGAFLGYQANQYLGFE
LGYDWLGRMPYKGSVNNGAFKAQGVQLAAKLSYPIMDDLDIYTRLGGMVWRADSKANYGNGTRLSDHDTGVSPLAAVGVE
YALTKNWATRLDYQFVSNIGDAGTVGARPDNTMLSLGVSYRFGQDDVVAPAPAPAPAPVVETKRFTLKSDVLFNFNKSTL
KAEGQQALDQLYTQLSAMDPKDGSAVVLGYTDAVGSDQYNQKLSEKRAQSVVDYLVSKGIPSEKISARGMGEADSVTGNT
CGYKAGRATKAQIACLAPDRRVEIEVKGIKDVVTQPQG

Specific function: Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes [H

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787191, Length=359, Percent_Identity=74.3732590529248, Blast_Score=521, Evalue=1e-149,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Mi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR002368
- InterPro:   IPR006690
- InterPro:   IPR000498
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA; PF01389 OmpA_membrane [H]

EC number: NA

Molecular weight: Translated: 38258; Mature: 38258

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS01068 OMPA_1 ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTAIALAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFYGNGYQNGIGNGPTHK
CCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCH
DQLGAGAFLGYQANQYLGFELGYDWLGRMPYKGSVNNGAFKAQGVQLAAKLSYPIMDDLD
HHCCCCEEEECCCCCEEEEEECHHHHCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCHH
IYTRLGGMVWRADSKANYGNGTRLSDHDTGVSPLAAVGVEYALTKNWATRLDYQFVSNIG
HHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCC
DAGTVGARPDNTMLSLGVSYRFGQDDVVAPAPAPAPAPVVETKRFTLKSDVLFNFNKSTL
CCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCEEEECCHHHH
KAEGQQALDQLYTQLSAMDPKDGSAVVLGYTDAVGSDQYNQKLSEKRAQSVVDYLVSKGI
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PSEKISARGMGEADSVTGNTCGYKAGRATKAQIACLAPDRRVEIEVKGIKDVVTQPQG
CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHCCCCC
>Mature Secondary Structure
MKKTAIALAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFYGNGYQNGIGNGPTHK
CCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCH
DQLGAGAFLGYQANQYLGFELGYDWLGRMPYKGSVNNGAFKAQGVQLAAKLSYPIMDDLD
HHCCCCEEEECCCCCEEEEEECHHHHCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCHH
IYTRLGGMVWRADSKANYGNGTRLSDHDTGVSPLAAVGVEYALTKNWATRLDYQFVSNIG
HHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCC
DAGTVGARPDNTMLSLGVSYRFGQDDVVAPAPAPAPAPVVETKRFTLKSDVLFNFNKSTL
CCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCEEEECCHHHH
KAEGQQALDQLYTQLSAMDPKDGSAVVLGYTDAVGSDQYNQKLSEKRAQSVVDYLVSKGI
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PSEKISARGMGEADSVTGNTCGYKAGRATKAQIACLAPDRRVEIEVKGIKDVVTQPQG
CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6092858 [H]