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The map label for this gene is aspC [H]

Identifier: 157369972

GI number: 157369972

Start: 1901807

End: 1903012

Strand: Reverse

Name: aspC [H]

Synonym: Spro_1729

Alternate gene names: 157369972

Gene position: 1903012-1901807 (Counterclockwise)

Preceding gene: 157369973

Following gene: 157369964

Centisome position: 34.93

GC content: 55.14

Gene sequence:

>1206_bases
ATGGAAGCACCTGACATGTTTGAAAAAATCACTGCTGCACCTGCCGATCCGATCCTGGGTCTGACCGACATTTTCCGCGC
TGACGCTCGTCCTAACAAAATCAACCTGGGGATTGGCGTTTATAAAGATGAAACCGGTAAAACTCCGGTGCTGACCAGCG
TTAAAAAAGCTGAGCAGTATCTGCTGGAAAATGAGACCACCAAAAACTATCTCGGCATTGAAGGTATTCCGGCGTTCGCC
AACTGTACGCAAGAGCTGCTGTTCGGCAAACAAAGCCCAATTATTGCCGACAAGCGTGCGCGCACTGCACAAACTCCTGG
TGGCACCGGCGGCCTGCGTGTTGCAGCTGACTTCATCGCCAACCAGACCAGCGCGAAACGCATCTGGATCAGCAACCCAA
GCTGGCCGAACCACAACAACGTGTTTGGTGCAGTCGGTCTGGAAGTGTTGGAATACGCTTACTACGACGCCGCCAATCAT
GCGCTGGACTTCGATGGTCTGCTCCGCAGCCTGCAACAGGCTCAGGCCGGCGATGTGGTGCTGTTCCACGGTTGCTGCCA
TAACCCAACCGGCATCGACCCAACGGCTGAGCAGTGGGCACAATTGGCCGAGCTGTCTGTGGCTAACGGTTGGTTGCCAC
TGTTTGACTTCGCATACCAGGGCTTTGCGAAAGGATTGGAAGAAGATGCTCAGGGCCTGCGTATTTTTGCCGCCAAGCAT
CAGGAACTGATCGTCGCCAGTTCTTACTCGAAGAACTTCGGTCTTTACAACGAACGCGTGGGTGCCTGTACCGTCGTTGC
TGCTGATGCAGAAACCGCCGATCGTGCCTTCAGCCAGGTGAAAGCGGCTATCCGCGCCAACTACTCCAACCCGCCGTCAC
ACGGTGCTGCCATTGTGGCAACCATCTTGGGCGACGATGCGTTGCGTGCGCTGTGGGAGCAGGAACTGACTGACATGCGT
CAACGTATTCACCGCATGCGTCAGCTGTTTGTGAATACCCTGCAGGAGAAAGGCGCTGAGCAGGACTTCAGCTTTATCAT
CAATCAGAACGGCATGTTCTCATTCAGCGGGCTGACCAAAGAACAGGTTCTGCGTTTGCGTGAGGAATTTGGCGTCTACG
CCGTTAACTCCGGCCGCGTTAACGTTGCCGGCATGACACCAGACAATATGGCGCCGCTGTGCGAAGCCATCGTCGCCGTG
CTGTAA

Upstream 100 bases:

>100_bases
ATATGCGTCCTTCACAAGATCGAGGTGTTTTTCTCGCAAACGGTTGGCAAAGGGCATAACTGGCGCTACCCTGATGCTTC
TGTCTGCTTAACTCCGAGCC

Downstream 100 bases:

>100_bases
AACCGTCGCGCGACACATAGCAAAAGGGGCGCTCAAAGCGCCCCTTAGTTATTTCTGCCGGAAATAACTTACCAGATGGC
CGGCTCTTCACGCAGGAACG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MEAPDMFEKITAAPADPILGLTDIFRADARPNKINLGIGVYKDETGKTPVLTSVKKAEQYLLENETTKNYLGIEGIPAFA
NCTQELLFGKQSPIIADKRARTAQTPGGTGGLRVAADFIANQTSAKRIWISNPSWPNHNNVFGAVGLEVLEYAYYDAANH
ALDFDGLLRSLQQAQAGDVVLFHGCCHNPTGIDPTAEQWAQLAELSVANGWLPLFDFAYQGFAKGLEEDAQGLRIFAAKH
QELIVASSYSKNFGLYNERVGACTVVAADAETADRAFSQVKAAIRANYSNPPSHGAAIVATILGDDALRALWEQELTDMR
QRIHRMRQLFVNTLQEKGAEQDFSFIINQNGMFSFSGLTKEQVLRLREEFGVYAVNSGRVNVAGMTPDNMAPLCEAIVAV
L

Sequences:

>Translated_401_residues
MEAPDMFEKITAAPADPILGLTDIFRADARPNKINLGIGVYKDETGKTPVLTSVKKAEQYLLENETTKNYLGIEGIPAFA
NCTQELLFGKQSPIIADKRARTAQTPGGTGGLRVAADFIANQTSAKRIWISNPSWPNHNNVFGAVGLEVLEYAYYDAANH
ALDFDGLLRSLQQAQAGDVVLFHGCCHNPTGIDPTAEQWAQLAELSVANGWLPLFDFAYQGFAKGLEEDAQGLRIFAAKH
QELIVASSYSKNFGLYNERVGACTVVAADAETADRAFSQVKAAIRANYSNPPSHGAAIVATILGDDALRALWEQELTDMR
QRIHRMRQLFVNTLQEKGAEQDFSFIINQNGMFSFSGLTKEQVLRLREEFGVYAVNSGRVNVAGMTPDNMAPLCEAIVAV
L
>Mature_401_residues
MEAPDMFEKITAAPADPILGLTDIFRADARPNKINLGIGVYKDETGKTPVLTSVKKAEQYLLENETTKNYLGIEGIPAFA
NCTQELLFGKQSPIIADKRARTAQTPGGTGGLRVAADFIANQTSAKRIWISNPSWPNHNNVFGAVGLEVLEYAYYDAANH
ALDFDGLLRSLQQAQAGDVVLFHGCCHNPTGIDPTAEQWAQLAELSVANGWLPLFDFAYQGFAKGLEEDAQGLRIFAAKH
QELIVASSYSKNFGLYNERVGACTVVAADAETADRAFSQVKAAIRANYSNPPSHGAAIVATILGDDALRALWEQELTDMR
QRIHRMRQLFVNTLQEKGAEQDFSFIINQNGMFSFSGLTKEQVLRLREEFGVYAVNSGRVNVAGMTPDNMAPLCEAIVAV
L

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=393, Percent_Identity=41.2213740458015, Blast_Score=311, Evalue=7e-85,
Organism=Homo sapiens, GI4504067, Length=405, Percent_Identity=40.9876543209877, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=28.7206266318538, Blast_Score=161, Evalue=8e-40,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=85.1010101010101, Blast_Score=716, Evalue=0.0,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=43.5768261964735, Blast_Score=352, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI71981858, Length=392, Percent_Identity=41.3265306122449, Blast_Score=329, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI25147133, Length=392, Percent_Identity=40.5612244897959, Blast_Score=327, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI17569539, Length=396, Percent_Identity=38.3838383838384, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17569537, Length=394, Percent_Identity=31.4720812182741, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=37.914691943128, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17550384, Length=250, Percent_Identity=34.8, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=37.9310344827586, Blast_Score=289, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6322743, Length=433, Percent_Identity=33.7182448036951, Blast_Score=234, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=44.6969696969697, Blast_Score=336, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=44.6969696969697, Blast_Score=335, Evalue=2e-92,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=45.2442159383033, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=38.8471177944862, Blast_Score=301, Evalue=4e-82,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=38.8471177944862, Blast_Score=301, Evalue=5e-82,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43793; Mature: 43793

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAPDMFEKITAAPADPILGLTDIFRADARPNKINLGIGVYKDETGKTPVLTSVKKAEQY
CCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHH
LLENETTKNYLGIEGIPAFANCTQELLFGKQSPIIADKRARTAQTPGGTGGLRVAADFIA
HHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
NQTSAKRIWISNPSWPNHNNVFGAVGLEVLEYAYYDAANHALDFDGLLRSLQQAQAGDVV
CCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEE
LFHGCCHNPTGIDPTAEQWAQLAELSVANGWLPLFDFAYQGFAKGLEEDAQGLRIFAAKH
EEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECC
QELIVASSYSKNFGLYNERVGACTVVAADAETADRAFSQVKAAIRANYSNPPSHGAAIVA
CEEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEH
TILGDDALRALWEQELTDMRQRIHRMRQLFVNTLQEKGAEQDFSFIINQNGMFSFSGLTK
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCH
EQVLRLREEFGVYAVNSGRVNVAGMTPDNMAPLCEAIVAVL
HHHHHHHHHCCEEEEECCEEEEECCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MEAPDMFEKITAAPADPILGLTDIFRADARPNKINLGIGVYKDETGKTPVLTSVKKAEQY
CCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHH
LLENETTKNYLGIEGIPAFANCTQELLFGKQSPIIADKRARTAQTPGGTGGLRVAADFIA
HHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
NQTSAKRIWISNPSWPNHNNVFGAVGLEVLEYAYYDAANHALDFDGLLRSLQQAQAGDVV
CCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEE
LFHGCCHNPTGIDPTAEQWAQLAELSVANGWLPLFDFAYQGFAKGLEEDAQGLRIFAAKH
EEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECC
QELIVASSYSKNFGLYNERVGACTVVAADAETADRAFSQVKAAIRANYSNPPSHGAAIVA
CEEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEH
TILGDDALRALWEQELTDMRQRIHRMRQLFVNTLQEKGAEQDFSFIINQNGMFSFSGLTK
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCH
EQVLRLREEFGVYAVNSGRVNVAGMTPDNMAPLCEAIVAVL
HHHHHHHHHCCEEEEECCEEEEECCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]