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The map label for this gene is lolA

Identifier: 157369927

GI number: 157369927

Start: 1845588

End: 1846199

Strand: Direct

Name: lolA

Synonym: Spro_1684

Alternate gene names: 157369927

Gene position: 1845588-1846199 (Clockwise)

Preceding gene: 157369926

Following gene: 157369928

Centisome position: 33.87

GC content: 54.58

Gene sequence:

>612_bases
ATGAAAAAACTGTTAGTTGCCTGTTGTCTGCTTTCGGGATTCGCTTCCACCTCTGTGCTGGCCGACGCCGCGCAGGATTT
GCAAAGTCGCCTGGCGAAAGTGAACAGTTTCCACGCCAGCTTCTCCCAGACCGTGACCAGCAGCGATGGTGCTGCGGTAC
AGCAGGGTGAAGGTGAACTTTGGGTGAAACGTCCCAACCTGTTTAACTGGCACATGACCTCGCCGGATGAGAGCGTGCTG
GTATCAGACGGTCAGACCCTGTGGTTCTACAACCCCTTTGTTGAGCAGGTGACCGCCACCTGGCTGAAAAATGCCACCGG
CAATACGCCGTTTATGCTGATCACCCGCAATAACGCCAATGACTGGAAACAGTACAACGTTAAACAGAAGGGTAATGATT
TCGAGCTGACGCCAAAATCCAGCAGCGGCAACCTGAAACAGTTCGCCATCAGCGTGGATAACAGCGGCACTATCCGCAAT
TTTGCCGCGGTTGAGCAGGACGGCCAGCGCAGCTCTTACACGCTGAAAAGCCAGCAGAATGTTGCTGCCGATGCCAGCAA
ATTTAAATTTACCCCGCCGAAGGGGGTGACGCTGGACGACCAGCGCCAGTGA

Upstream 100 bases:

>100_bases
CTGCCGGCGAATGGCTTCGGGTAGAGTGAAGGTGTTGGGGTTCATTTGACCCGCACGGCACCGCCTTGCGGTTAACGCAT
TTCATAAGGTATCTGGAATA

Downstream 100 bases:

>100_bases
GGTCCGCGTGAGTAATATGTCGCTCGATTTTTCCCAGAATGAATTCCAGCCGTTGGCCGCGCGGATGCGGCCGACCACGC
TGGCACAGTATATCGGCCAG

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKKLLVACCLLSGFASTSVLADAAQDLQSRLAKVNSFHASFSQTVTSSDGAAVQQGEGELWVKRPNLFNWHMTSPDESVL
VSDGQTLWFYNPFVEQVTATWLKNATGNTPFMLITRNNANDWKQYNVKQKGNDFELTPKSSSGNLKQFAISVDNSGTIRN
FAAVEQDGQRSSYTLKSQQNVAADASKFKFTPPKGVTLDDQRQ

Sequences:

>Translated_203_residues
MKKLLVACCLLSGFASTSVLADAAQDLQSRLAKVNSFHASFSQTVTSSDGAAVQQGEGELWVKRPNLFNWHMTSPDESVL
VSDGQTLWFYNPFVEQVTATWLKNATGNTPFMLITRNNANDWKQYNVKQKGNDFELTPKSSSGNLKQFAISVDNSGTIRN
FAAVEQDGQRSSYTLKSQQNVAADASKFKFTPPKGVTLDDQRQ
>Mature_203_residues
MKKLLVACCLLSGFASTSVLADAAQDLQSRLAKVNSFHASFSQTVTSSDGAAVQQGEGELWVKRPNLFNWHMTSPDESVL
VSDGQTLWFYNPFVEQVTATWLKNATGNTPFMLITRNNANDWKQYNVKQKGNDFELTPKSSSGNLKQFAISVDNSGTIRN
FAAVEQDGQRSSYTLKSQQNVAADASKFKFTPPKGVTLDDQRQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=203, Percent_Identity=72.4137931034483, Blast_Score=318, Evalue=2e-88,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_SERP5 (A8GCE8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477916.1
- ProteinModelPortal:   A8GCE8
- SMR:   A8GCE8
- STRING:   A8GCE8
- GeneID:   5604211
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1684
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   VDIDDQR
- ProtClustDB:   PRK00031
- BioCyc:   SPRO399741:SPRO_1684-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 22410; Mature: 22410

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLVACCLLSGFASTSVLADAAQDLQSRLAKVNSFHASFSQTVTSSDGAAVQQGEGEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCE
WVKRPNLFNWHMTSPDESVLVSDGQTLWFYNPFVEQVTATWLKNATGNTPFMLITRNNAN
EEECCCEEEEEECCCCCEEEEECCCEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCC
DWKQYNVKQKGNDFELTPKSSSGNLKQFAISVDNSGTIRNFAAVEQDGQRSSYTLKSQQN
CHHHCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCEEHHHHHCCCCCCCCEEECCCCC
VAADASKFKFTPPKGVTLDDQRQ
CCCCCHHEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKKLLVACCLLSGFASTSVLADAAQDLQSRLAKVNSFHASFSQTVTSSDGAAVQQGEGEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCE
WVKRPNLFNWHMTSPDESVLVSDGQTLWFYNPFVEQVTATWLKNATGNTPFMLITRNNAN
EEECCCEEEEEECCCCCEEEEECCCEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCC
DWKQYNVKQKGNDFELTPKSSSGNLKQFAISVDNSGTIRNFAAVEQDGQRSSYTLKSQQN
CHHHCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCEEHHHHHCCCCCCCCEEECCCCC
VAADASKFKFTPPKGVTLDDQRQ
CCCCCHHEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA