Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 157369844

GI number: 157369844

Start: 1754195

End: 1755208

Strand: Direct

Name: galE [H]

Synonym: Spro_1601

Alternate gene names: 157369844

Gene position: 1754195-1755208 (Clockwise)

Preceding gene: 157369843

Following gene: 157369845

Centisome position: 32.19

GC content: 49.21

Gene sequence:

>1014_bases
ATGGTTATTTTAGTCACTGGCGGTGCCGGTTATATCGGTTCTCACACAGTTCTGACCCTGCTGGAACGTGGTGAAAAGGT
CATTGTGTTAGATAACCTGTCGAACTCATCAGAAGAGTCTTTGCGTCGTGTAGAAAAGTTAACGGGCAAAGCTGCCGTGT
TTTACCAAGGGGATATCCAAAATGCTGAATGTTTGCGTCGCATCTTTGATGACCACGAAATTTCAGCAGTGATCCATTTT
GCCGGCCTGAAAGCAGTAGGTGAGTCGACTCGCAAGCCACTTGAGTACTATCAAAACAATGTTGCCGGTACGCTGGTGTT
ACTGGATGAAATGCGTCGTGCAGGTGTTCACCAATTTATCTTTAGCTCTTCCGCTACGGTTTATGGCGCTAACTCACCGG
TTCCTTATGTGGAAACTACGCCGATTGGCGGGACTACCAGCCCATATGGGACCTCCAAATTGATGGTAGAGCAGGTTTTG
CAGGATTTTGCCAAGGCTGAGCCCCAGTTTTCCATTATTGCCCTGCGTTACTTCAATCCGGTCGGTGCGCATGAGTCAGG
TTTGATTGGTGAAGATCCAAATGGTATCCCAAACAATCTGTTGCCCTATATCTCTCAGGTAGCAATTGGCAAACTGGATA
AGTTGGGCATTTTCGGTGGTGATTACCCAACTGAAGATGGCACCGGTGAACGTGATTACATCCACGTGATGGATTTGGCC
GAAGGGCATCTGATGGCGATGGATCATCTGAATAAAGTCGGAGGCTTCAAAGCATACAATCTGGGAGCAGGGGCAGGGCA
CTCGGTCTTGGCAATGGTGCAGGCTTTTGAAAAAGCATCTGGAGTGAAGATCCCATATCAGATCTTACCGCGTCGTGACG
GAGATCTGCCGGCCTTCTGGGCTGACGCGAATCTTGCCCGTGAGGAGCTGGGTTGGGAAGTGCGGCGCGGTATCGATGAA
ATGATGCGCGATACCTGGAATTGGCAAAAGAATAACCCGAAAGGTTATCGGTAG

Upstream 100 bases:

>100_bases
GATATATAAGGTATTTGAATTAGAGTAAGTCGGATAGAAAGTTTGCAGACCTGATGCAGCGAATCTATTTAAACGGCATG
GATAAAAATAAGGAGTTGTT

Downstream 100 bases:

>100_bases
CACACTGCATTTGTTGATATTACCGTGCTGGCAGGTGCGGTAATGGCTTACATACTTCATTTTTTCTTTCCCAAAGCCCC
CTTTTCATTGCGCGGGCAAT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MVILVTGGAGYIGSHTVLTLLERGEKVIVLDNLSNSSEESLRRVEKLTGKAAVFYQGDIQNAECLRRIFDDHEISAVIHF
AGLKAVGESTRKPLEYYQNNVAGTLVLLDEMRRAGVHQFIFSSSATVYGANSPVPYVETTPIGGTTSPYGTSKLMVEQVL
QDFAKAEPQFSIIALRYFNPVGAHESGLIGEDPNGIPNNLLPYISQVAIGKLDKLGIFGGDYPTEDGTGERDYIHVMDLA
EGHLMAMDHLNKVGGFKAYNLGAGAGHSVLAMVQAFEKASGVKIPYQILPRRDGDLPAFWADANLAREELGWEVRRGIDE
MMRDTWNWQKNNPKGYR

Sequences:

>Translated_337_residues
MVILVTGGAGYIGSHTVLTLLERGEKVIVLDNLSNSSEESLRRVEKLTGKAAVFYQGDIQNAECLRRIFDDHEISAVIHF
AGLKAVGESTRKPLEYYQNNVAGTLVLLDEMRRAGVHQFIFSSSATVYGANSPVPYVETTPIGGTTSPYGTSKLMVEQVL
QDFAKAEPQFSIIALRYFNPVGAHESGLIGEDPNGIPNNLLPYISQVAIGKLDKLGIFGGDYPTEDGTGERDYIHVMDLA
EGHLMAMDHLNKVGGFKAYNLGAGAGHSVLAMVQAFEKASGVKIPYQILPRRDGDLPAFWADANLAREELGWEVRRGIDE
MMRDTWNWQKNNPKGYR
>Mature_337_residues
MVILVTGGAGYIGSHTVLTLLERGEKVIVLDNLSNSSEESLRRVEKLTGKAAVFYQGDIQNAECLRRIFDDHEISAVIHF
AGLKAVGESTRKPLEYYQNNVAGTLVLLDEMRRAGVHQFIFSSSATVYGANSPVPYVETTPIGGTTSPYGTSKLMVEQVL
QDFAKAEPQFSIIALRYFNPVGAHESGLIGEDPNGIPNNLLPYISQVAIGKLDKLGIFGGDYPTEDGTGERDYIHVMDLA
EGHLMAMDHLNKVGGFKAYNLGAGAGHSVLAMVQAFEKASGVKIPYQILPRRDGDLPAFWADANLAREELGWEVRRGIDE
MMRDTWNWQKNNPKGYR

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=55.8823529411765, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=55.8823529411765, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=55.8823529411765, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI7657641, Length=276, Percent_Identity=29.3478260869565, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI4504031, Length=357, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=61.9047619047619, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1788353, Length=368, Percent_Identity=27.1739130434783, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI48994969, Length=364, Percent_Identity=26.3736263736264, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=51.8840579710145, Blast_Score=359, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=51.2968299711816, Blast_Score=357, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI17568069, Length=343, Percent_Identity=22.4489795918367, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=345, Percent_Identity=48.695652173913, Blast_Score=338, Evalue=6e-94,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=55.1020408163265, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI21356223, Length=337, Percent_Identity=24.6290801186944, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37020; Mature: 37020

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILVTGGAGYIGSHTVLTLLERGEKVIVLDNLSNSSEESLRRVEKLTGKAAVFYQGDIQ
CEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCC
NAECLRRIFDDHEISAVIHFAGLKAVGESTRKPLEYYQNNVAGTLVLLDEMRRAGVHQFI
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
FSSSATVYGANSPVPYVETTPIGGTTSPYGTSKLMVEQVLQDFAKAEPQFSIIALRYFNP
HCCCCEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
VGAHESGLIGEDPNGIPNNLLPYISQVAIGKLDKLGIFGGDYPTEDGTGERDYIHVMDLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEEEEECC
EGHLMAMDHLNKVGGFKAYNLGAGAGHSVLAMVQAFEKASGVKIPYQILPRRDGDLPAFW
CCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEE
ADANLAREELGWEVRRGIDEMMRDTWNWQKNNPKGYR
CCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVILVTGGAGYIGSHTVLTLLERGEKVIVLDNLSNSSEESLRRVEKLTGKAAVFYQGDIQ
CEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCC
NAECLRRIFDDHEISAVIHFAGLKAVGESTRKPLEYYQNNVAGTLVLLDEMRRAGVHQFI
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
FSSSATVYGANSPVPYVETTPIGGTTSPYGTSKLMVEQVLQDFAKAEPQFSIIALRYFNP
HCCCCEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
VGAHESGLIGEDPNGIPNNLLPYISQVAIGKLDKLGIFGGDYPTEDGTGERDYIHVMDLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEEEEECC
EGHLMAMDHLNKVGGFKAYNLGAGAGHSVLAMVQAFEKASGVKIPYQILPRRDGDLPAFW
CCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEE
ADANLAREELGWEVRRGIDEMMRDTWNWQKNNPKGYR
CCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7507102 [H]