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The map label for this gene is mglB [H]

Identifier: 157369806

GI number: 157369806

Start: 1703171

End: 1704163

Strand: Direct

Name: mglB [H]

Synonym: Spro_1563

Alternate gene names: 157369806

Gene position: 1703171-1704163 (Clockwise)

Preceding gene: 157369805

Following gene: 157369807

Centisome position: 31.26

GC content: 51.96

Gene sequence:

>993_bases
ATGAATAAGAAGGTTTTCACCCTGGCCGCGACGGCCGCAGCCATGATGTTTGGCGCCGCAGCACATGCAGATACCCGTAT
TGGCGTCACAATTTATAAATATGACGACAACTTTATGTCGGTGGTACGCAAGGCTATCGAGAAAGACGCCAAGGCCTCTC
CGGACGTCACCCTGCTGATGAATGACTCGCAGAATGACCAATCCAAACAAAACGATCAGATTGACGTGCTGATCGCCAAG
GGCGTTAAAGCACTGGCGATCAACCTGGTTGACCCGGCAGCCGCCCCGGTGGTGATTGATAAGGCGCGCGCAAACGATAT
CCCTATCGTGTTTTACAACAAAGAGCCTTCCCGTAAAGCGCTGGACAGCTATGACAAAGCTTATTACGTGGGGACCGACT
CTAAAGAGTCCGGTGTGATCCAGGGCAAACTGATCGAGAAGCACTGGAAGGCTAACCCGAACTGGGATCTGAACAAAGAT
GGTCAGATTCAGTATGTGTTGCTCAAAGGTGAGCCAGGCCACCCGGATGCTGAAGCGCGTACCACCTACGTGACTAAAAC
GCTGAACGACGACGGTATCAAGACGCAGGCATTGCAGATGGACACCGCAATGTGGGACACCGCACAGGCTAAAGACAAGA
TGGATGCCTGGCTGTCCGGCCCTAATGCCAACAAAATAGAAGTGGTGATTGCCAACAACGATGCGATGGCAATGGGCGCG
GTAGAAGCGCTGAAAGCGCATAACAAATCCAGCATTCCGGTATTCGGTGTGGATGCGTTGCCTGAAGCCCTGGCGATGGT
GAAATCCGGCGCTATGGCAGGGACAGTACTGAACGATGCCGACAATCAGGCTAAAGCCACTTTCGAACTGGCGAAAAACC
TGGCTGCAGGCAAACCGGCCGCCGATGGCACCCAATATAAGATTGAAAATAAAGTGGTGCGCATTGCTTACGTTGGCGTA
GATAAAGACAACCTGTCTCAGTTTATTAAGTAA

Upstream 100 bases:

>100_bases
TCACGGATGACAGGGAAACTGCCAGGCCCGGTTGTGCATTCGCCACCGGTTACCTTTGGCCTAACACCGAGCAAGACCCT
ACATAAACCGGAGACACACA

Downstream 100 bases:

>100_bases
GTTCTGAATGACCCCGCCTGAGGTGCGCTGCCCAGCGCCAACACCAGGAAAGCCGCAGGCGGGGAAATTTATTCTTCAAA
TCACAGCCTATACCCGATGA

Product: periplasmic binding protein/LacI transcriptional regulator

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: GBP; D-galactose/ D-glucose-binding protein; GGBP [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNKKVFTLAATAAAMMFGAAAHADTRIGVTIYKYDDNFMSVVRKAIEKDAKASPDVTLLMNDSQNDQSKQNDQIDVLIAK
GVKALAINLVDPAAAPVVIDKARANDIPIVFYNKEPSRKALDSYDKAYYVGTDSKESGVIQGKLIEKHWKANPNWDLNKD
GQIQYVLLKGEPGHPDAEARTTYVTKTLNDDGIKTQALQMDTAMWDTAQAKDKMDAWLSGPNANKIEVVIANNDAMAMGA
VEALKAHNKSSIPVFGVDALPEALAMVKSGAMAGTVLNDADNQAKATFELAKNLAAGKPAADGTQYKIENKVVRIAYVGV
DKDNLSQFIK

Sequences:

>Translated_330_residues
MNKKVFTLAATAAAMMFGAAAHADTRIGVTIYKYDDNFMSVVRKAIEKDAKASPDVTLLMNDSQNDQSKQNDQIDVLIAK
GVKALAINLVDPAAAPVVIDKARANDIPIVFYNKEPSRKALDSYDKAYYVGTDSKESGVIQGKLIEKHWKANPNWDLNKD
GQIQYVLLKGEPGHPDAEARTTYVTKTLNDDGIKTQALQMDTAMWDTAQAKDKMDAWLSGPNANKIEVVIANNDAMAMGA
VEALKAHNKSSIPVFGVDALPEALAMVKSGAMAGTVLNDADNQAKATFELAKNLAAGKPAADGTQYKIENKVVRIAYVGV
DKDNLSQFIK
>Mature_330_residues
MNKKVFTLAATAAAMMFGAAAHADTRIGVTIYKYDDNFMSVVRKAIEKDAKASPDVTLLMNDSQNDQSKQNDQIDVLIAK
GVKALAINLVDPAAAPVVIDKARANDIPIVFYNKEPSRKALDSYDKAYYVGTDSKESGVIQGKLIEKHWKANPNWDLNKD
GQIQYVLLKGEPGHPDAEARTTYVTKTLNDDGIKTQALQMDTAMWDTAQAKDKMDAWLSGPNANKIEVVIANNDAMAMGA
VEALKAHNKSSIPVFGVDALPEALAMVKSGAMAGTVLNDADNQAKATFELAKNLAAGKPAADGTQYKIENKVVRIAYVGV
DKDNLSQFIK

Specific function: This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788473, Length=331, Percent_Identity=85.8006042296072, Blast_Score=578, Evalue=1e-166,
Organism=Escherichia coli, GI1788898, Length=264, Percent_Identity=26.1363636363636, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790192, Length=277, Percent_Identity=25.9927797833935, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 4720 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 1320 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35678; Mature: 35678

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKVFTLAATAAAMMFGAAAHADTRIGVTIYKYDDNFMSVVRKAIEKDAKASPDVTLLM
CCCEEEEHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEE
NDSQNDQSKQNDQIDVLIAKGVKALAINLVDPAAAPVVIDKARANDIPIVFYNKEPSRKA
CCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCEEEECCCCCCCCEEEECCCCCHHH
LDSYDKAYYVGTDSKESGVIQGKLIEKHWKANPNWDLNKDGQIQYVLLKGEPGHPDAEAR
HHCCCCEEEEECCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCE
TTYVTKTLNDDGIKTQALQMDTAMWDTAQAKDKMDAWLSGPNANKIEVVIANNDAMAMGA
EEEEEEECCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHH
VEALKAHNKSSIPVFGVDALPEALAMVKSGAMAGTVLNDADNQAKATFELAKNLAAGKPA
HHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCC
ADGTQYKIENKVVRIAYVGVDKDNLSQFIK
CCCCEEEECCEEEEEEEEECCHHHHHHHCC
>Mature Secondary Structure
MNKKVFTLAATAAAMMFGAAAHADTRIGVTIYKYDDNFMSVVRKAIEKDAKASPDVTLLM
CCCEEEEHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEE
NDSQNDQSKQNDQIDVLIAKGVKALAINLVDPAAAPVVIDKARANDIPIVFYNKEPSRKA
CCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCEEEECCCCCCCCEEEECCCCCHHH
LDSYDKAYYVGTDSKESGVIQGKLIEKHWKANPNWDLNKDGQIQYVLLKGEPGHPDAEAR
HHCCCCEEEEECCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCE
TTYVTKTLNDDGIKTQALQMDTAMWDTAQAKDKMDAWLSGPNANKIEVVIANNDAMAMGA
EEEEEEECCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHH
VEALKAHNKSSIPVFGVDALPEALAMVKSGAMAGTVLNDADNQAKATFELAKNLAAGKPA
HHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCC
ADGTQYKIENKVVRIAYVGVDKDNLSQFIK
CCCCEEEECCEEEEEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA