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The map label for this gene is bdlA [H]

Identifier: 157369715

GI number: 157369715

Start: 1607323

End: 1608627

Strand: Direct

Name: bdlA [H]

Synonym: Spro_1472

Alternate gene names: 157369715

Gene position: 1607323-1608627 (Clockwise)

Preceding gene: 157369714

Following gene: 157369716

Centisome position: 29.5

GC content: 54.25

Gene sequence:

>1305_bases
ATGCTGTTACGATTCAGTCAGTTAAATACCCACAGTCGTGCGGAATTGAACGCGATAGAAAATGCCGTTGCCATGATTGT
ATTTAAACCCGACGGCACCGTGCTGCGAGCCAATGATTTATTTCTGCAAACTATGGGATTCCAGCGCCAGGAAGTGATCG
GCCAACATCACCGTATTTTTTGTGACCCGCAATATGTTACGAGTACGGCATACCGTAAGCACTGGGAAATGTTAAATCAT
GGCAAGCCGATTACCGACAATATAAAGCGCATTCGCAAAGACGGTGAAGTTGTATGGCTGCAGGGTACCTATACCCCGGT
ATTGAACAAGCAGGGGCGGGTGATGGAGATCGTCAAGATTGCCAGCGTGGTGACCGAACGCATTACCCAGGCACAGGAAC
ATCAAAGTTTACTGGCAGCGTTAAATCGATCTATGGCGATGATCACTTTCAACGCACAGGGAAAGATCCTCGACGCGAAC
GACAATATGTTGAATCTGATGGGTTATCGGCTGGAGGAGGCGCGCGGACAGTCGCATGCGGTGCTCTGCCCGCCAGAATT
TGCCGCCTCTGACGATTACCGTCAGCACTGGCAGCGTTTGGCACGCGGCGAGTTTATCACCGGGCGTTTTGAGCGGGTAA
ATCGTCGTGGGGAGCGAGTCTGGCTGGAGGCCAGTTATAACCCGATCCTCAACGAAGATGGGCGGCTGGTGAAAGTGGTG
AAAATCGCTCAGGACATTACCCGGCTGATGATCCAGCAGCAGCATGAGGAAGAGATGGTACGCAATGCGCACCATCTTTC
TTTGGATACCGACAGAACCGCGGCGCAGGGGGCGGTGATCGTGCAGCAGGCGGTGGCGGGTATGCAGCAGGTGGAAGCGG
CCGCACGCGATACTTCCGCCGTGGTCAGCGAACTGGGCAAAGGGTCACAGCAAATTGGTGCCATGGTGGAGTCAATCCGT
AAAATTGCTTCTCAAACCAATTTGCTGGCAATCAATGCTTCTATTGAGGCCGCGCACGCGGGGGAACACGGGCGCGGTTT
TGCCGTGGTCGCCAACGAAGTGCGTACTCTGGCAGAACAGTCCCGCCAGGCGGCGACAGAAATCGAAAGGATTACCAAAG
CGATTCAACAGGGCGTGGCGGCGGCGATTGCCGGAATGGCGGTTTGTGTGGAGCAAGCGGGCGGTGGCGTTGCCCTGACG
CATGATGCCGGTGAGGTGATCAATCAGGTGAATGTGGGCATGCAGGACGTGGTGAAACTTATGCAGACTTTCACGTCGGT
TAAACAAGAAGGTGCATTGCACTGA

Upstream 100 bases:

>100_bases
TTCTCTGGTTGATGCGCGCCTGCGTGTGGGCGCGGCGTGCGTAAAAATAAAATGAGAAGCCATTGTTCGCTAAATCATCT
GCCAGAAGGATTTTTACCCT

Downstream 100 bases:

>100_bases
TCGCCCCTGCGCTAGCCCTGGCAACGGGGTTAGCGCCTTTATCGCTTTACTATTCTCCTGATTGTTTATCTTTGGTTCAA
ACTCGCCGGTTTGACATTCT

Product: Pas/Pac sensor-containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MLLRFSQLNTHSRAELNAIENAVAMIVFKPDGTVLRANDLFLQTMGFQRQEVIGQHHRIFCDPQYVTSTAYRKHWEMLNH
GKPITDNIKRIRKDGEVVWLQGTYTPVLNKQGRVMEIVKIASVVTERITQAQEHQSLLAALNRSMAMITFNAQGKILDAN
DNMLNLMGYRLEEARGQSHAVLCPPEFAASDDYRQHWQRLARGEFITGRFERVNRRGERVWLEASYNPILNEDGRLVKVV
KIAQDITRLMIQQQHEEEMVRNAHHLSLDTDRTAAQGAVIVQQAVAGMQQVEAAARDTSAVVSELGKGSQQIGAMVESIR
KIASQTNLLAINASIEAAHAGEHGRGFAVVANEVRTLAEQSRQAATEIERITKAIQQGVAAAIAGMAVCVEQAGGGVALT
HDAGEVINQVNVGMQDVVKLMQTFTSVKQEGALH

Sequences:

>Translated_434_residues
MLLRFSQLNTHSRAELNAIENAVAMIVFKPDGTVLRANDLFLQTMGFQRQEVIGQHHRIFCDPQYVTSTAYRKHWEMLNH
GKPITDNIKRIRKDGEVVWLQGTYTPVLNKQGRVMEIVKIASVVTERITQAQEHQSLLAALNRSMAMITFNAQGKILDAN
DNMLNLMGYRLEEARGQSHAVLCPPEFAASDDYRQHWQRLARGEFITGRFERVNRRGERVWLEASYNPILNEDGRLVKVV
KIAQDITRLMIQQQHEEEMVRNAHHLSLDTDRTAAQGAVIVQQAVAGMQQVEAAARDTSAVVSELGKGSQQIGAMVESIR
KIASQTNLLAINASIEAAHAGEHGRGFAVVANEVRTLAEQSRQAATEIERITKAIQQGVAAAIAGMAVCVEQAGGGVALT
HDAGEVINQVNVGMQDVVKLMQTFTSVKQEGALH
>Mature_434_residues
MLLRFSQLNTHSRAELNAIENAVAMIVFKPDGTVLRANDLFLQTMGFQRQEVIGQHHRIFCDPQYVTSTAYRKHWEMLNH
GKPITDNIKRIRKDGEVVWLQGTYTPVLNKQGRVMEIVKIASVVTERITQAQEHQSLLAALNRSMAMITFNAQGKILDAN
DNMLNLMGYRLEEARGQSHAVLCPPEFAASDDYRQHWQRLARGEFITGRFERVNRRGERVWLEASYNPILNEDGRLVKVV
KIAQDITRLMIQQQHEEEMVRNAHHLSLDTDRTAAQGAVIVQQAVAGMQQVEAAARDTSAVVSELGKGSQQIGAMVESIR
KIASQTNLLAINASIEAAHAGEHGRGFAVVANEVRTLAEQSRQAATEIERITKAIQQGVAAAIAGMAVCVEQAGGGVALT
HDAGEVINQVNVGMQDVVKLMQTFTSVKQEGALH

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=173, Percent_Identity=36.4161849710983, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788195, Length=170, Percent_Identity=34.1176470588235, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788194, Length=122, Percent_Identity=44.2622950819672, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787690, Length=108, Percent_Identity=49.0740740740741, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789453, Length=122, Percent_Identity=38.5245901639344, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081921, Length=237, Percent_Identity=23.6286919831224, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 48081; Mature: 48081

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLRFSQLNTHSRAELNAIENAVAMIVFKPDGTVLRANDLFLQTMGFQRQEVIGQHHRIF
CEEEECCCCCCCHHHHHHHCCEEEEEEECCCCCEEEECHHHHHHHCCCHHHHHCCCCEEE
CDPQYVTSTAYRKHWEMLNHGKPITDNIKRIRKDGEVVWLQGTYTPVLNKQGRVMEIVKI
ECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHH
ASVVTERITQAQEHQSLLAALNRSMAMITFNAQGKILDANDNMLNLMGYRLEEARGQSHA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCCCCHHHHHHHHHHHCCCCCE
VLCPPEFAASDDYRQHWQRLARGEFITGRFERVNRRGERVWLEASYNPILNEDGRLVKVV
EECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEHHH
KIAQDITRLMIQQQHEEEMVRNAHHLSLDTDRTAAQGAVIVQQAVAGMQQVEAAARDTSA
HHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVSELGKGSQQIGAMVESIRKIASQTNLLAINASIEAAHAGEHGRGFAVVANEVRTLAEQ
HHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHH
SRQAATEIERITKAIQQGVAAAIAGMAVCVEQAGGGVALTHDAGEVINQVNVGMQDVVKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCHHHHHHH
MQTFTSVKQEGALH
HHHHHHHHHCCCCC
>Mature Secondary Structure
MLLRFSQLNTHSRAELNAIENAVAMIVFKPDGTVLRANDLFLQTMGFQRQEVIGQHHRIF
CEEEECCCCCCCHHHHHHHCCEEEEEEECCCCCEEEECHHHHHHHCCCHHHHHCCCCEEE
CDPQYVTSTAYRKHWEMLNHGKPITDNIKRIRKDGEVVWLQGTYTPVLNKQGRVMEIVKI
ECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHH
ASVVTERITQAQEHQSLLAALNRSMAMITFNAQGKILDANDNMLNLMGYRLEEARGQSHA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCCCCHHHHHHHHHHHCCCCCE
VLCPPEFAASDDYRQHWQRLARGEFITGRFERVNRRGERVWLEASYNPILNEDGRLVKVV
EECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEHHH
KIAQDITRLMIQQQHEEEMVRNAHHLSLDTDRTAAQGAVIVQQAVAGMQQVEAAARDTSA
HHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVSELGKGSQQIGAMVESIRKIASQTNLLAINASIEAAHAGEHGRGFAVVANEVRTLAEQ
HHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHH
SRQAATEIERITKAIQQGVAAAIAGMAVCVEQAGGGVALTHDAGEVINQVNVGMQDVVKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCHHHHHHH
MQTFTSVKQEGALH
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]