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The map label for this gene is dgdR [H]

Identifier: 157369674

GI number: 157369674

Start: 1561662

End: 1562531

Strand: Direct

Name: dgdR [H]

Synonym: Spro_1431

Alternate gene names: 157369674

Gene position: 1561662-1562531 (Clockwise)

Preceding gene: 157369670

Following gene: 157369679

Centisome position: 28.66

GC content: 61.84

Gene sequence:

>870_bases
ATGGGGCGAGTCACCTTCGATCTTGACGATCTGCGCAGTTACGTGACAGGCATTGAGCTGGGCAGTTTCGCTAAAGCGGC
AGAGCGGCTGGGGCGATCCACCTCGGCGGTCAGCGCGCATCTGAAAAAGCTGGAACAGCAGGTTGGCAGCCCCATCCTGC
GCAAGTCCGGGCGCGGCATGGTAATGACCGAAGCCGGCGAAACGCTGTTGGGCTACGCGCGTCGCTTACTGGAGCTCAAT
GATGAGGCCGCGACCGCAGTGCGCGGCTTGGATCTACAGGGCATTGTGCGGTTAGGGCTACAGGAGGACTTTGGTGAAAC
CTTTTTGCCACAGGTCTTGGGCAGTTTTGCCCGAGCGCATCCGCGCGTGCGTATCGAAGCGCGTATTGCCCGTAATGCTG
AACTGATCGAGTGGGTGTTGAAAGGACAACTGGATTTGTCGCTGGCGTGGGACGGTGGTATCAGCACGCCGTTTTATCAG
GCGCTGGGGCAACGGCAGATGCACTGGATCGCCTCCCCGCATTTTGAACTGGCCTCCTGGCGCCAGGGGGATGAACCTCT
GCCGCTGGTGATGTTTGATGCCCCTTGTCTGATGCGCAGCGCCGCGACTCAGGCGCTGGATCGTGCCGGTATAGCCTGGC
GTGTCGTCTTCACCAGTCGCAGCCTGAATGGCGTATGGGCGGCGGTCAGCGCCGGATTGGGGGTAACGGTGCGTACCGAC
GCCGGGTTGCCAGCGGGGCTGTCCCTTTTGCCACCCGACGCTTTGCCGGCGCTAAACCCGTTAGCTGTGGTGCTGCACCG
TGCCGAAGAAAACCCCTCGGCGGCGATCCAGCGTCTGGCGCAGATCGTCGCCGATCGGATCAACAGCTAG

Upstream 100 bases:

>100_bases
TTCTCCTGAAAGCGATTGACCGGCTGAGCATGACACGCCATCTTTGTGAGTAATATCGGCATTATTTTGACTGATGGTTC
TTAAAAACGGGATGGTTAGT

Downstream 100 bases:

>100_bases
TCCTGCTCGATCGGCTGCTTACCGCTTAACGCACCCCATTCGGTCCAGGCACCGTCATACAGTTTCACCTGCGGTGCACC
GAGTGACAGCAGGCCGAAAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MGRVTFDLDDLRSYVTGIELGSFAKAAERLGRSTSAVSAHLKKLEQQVGSPILRKSGRGMVMTEAGETLLGYARRLLELN
DEAATAVRGLDLQGIVRLGLQEDFGETFLPQVLGSFARAHPRVRIEARIARNAELIEWVLKGQLDLSLAWDGGISTPFYQ
ALGQRQMHWIASPHFELASWRQGDEPLPLVMFDAPCLMRSAATQALDRAGIAWRVVFTSRSLNGVWAAVSAGLGVTVRTD
AGLPAGLSLLPPDALPALNPLAVVLHRAEENPSAAIQRLAQIVADRINS

Sequences:

>Translated_289_residues
MGRVTFDLDDLRSYVTGIELGSFAKAAERLGRSTSAVSAHLKKLEQQVGSPILRKSGRGMVMTEAGETLLGYARRLLELN
DEAATAVRGLDLQGIVRLGLQEDFGETFLPQVLGSFARAHPRVRIEARIARNAELIEWVLKGQLDLSLAWDGGISTPFYQ
ALGQRQMHWIASPHFELASWRQGDEPLPLVMFDAPCLMRSAATQALDRAGIAWRVVFTSRSLNGVWAAVSAGLGVTVRTD
AGLPAGLSLLPPDALPALNPLAVVLHRAEENPSAAIQRLAQIVADRINS
>Mature_288_residues
GRVTFDLDDLRSYVTGIELGSFAKAAERLGRSTSAVSAHLKKLEQQVGSPILRKSGRGMVMTEAGETLLGYARRLLELND
EAATAVRGLDLQGIVRLGLQEDFGETFLPQVLGSFARAHPRVRIEARIARNAELIEWVLKGQLDLSLAWDGGISTPFYQA
LGQRQMHWIASPHFELASWRQGDEPLPLVMFDAPCLMRSAATQALDRAGIAWRVVFTSRSLNGVWAAVSAGLGVTVRTDA
GLPAGLSLLPPDALPALNPLAVVLHRAEENPSAAIQRLAQIVADRINS

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=289, Percent_Identity=33.9100346020761, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787806, Length=247, Percent_Identity=25.5060728744939, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788748, Length=302, Percent_Identity=25.8278145695364, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI157672245, Length=285, Percent_Identity=25.6140350877193, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082132, Length=234, Percent_Identity=23.9316239316239, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=255, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=28.0821917808219, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=150, Percent_Identity=30.6666666666667, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994962, Length=144, Percent_Identity=30.5555555555556, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31320; Mature: 31189

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRVTFDLDDLRSYVTGIELGSFAKAAERLGRSTSAVSAHLKKLEQQVGSPILRKSGRGM
CCCEEECHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCE
VMTEAGETLLGYARRLLELNDEAATAVRGLDLQGIVRLGLQEDFGETFLPQVLGSFARAH
EEECCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
PRVRIEARIARNAELIEWVLKGQLDLSLAWDGGISTPFYQALGQRQMHWIASPHFELASW
CCEEEEEHHHCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCHHHHHHHCCCCHHHHHC
RQGDEPLPLVMFDAPCLMRSAATQALDRAGIAWRVVFTSRSLNGVWAAVSAGLGVTVRTD
CCCCCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCEEEEEC
AGLPAGLSLLPPDALPALNPLAVVLHRAEENPSAAIQRLAQIVADRINS
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRVTFDLDDLRSYVTGIELGSFAKAAERLGRSTSAVSAHLKKLEQQVGSPILRKSGRGM
CCEEECHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCE
VMTEAGETLLGYARRLLELNDEAATAVRGLDLQGIVRLGLQEDFGETFLPQVLGSFARAH
EEECCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
PRVRIEARIARNAELIEWVLKGQLDLSLAWDGGISTPFYQALGQRQMHWIASPHFELASW
CCEEEEEHHHCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCHHHHHHHCCCCHHHHHC
RQGDEPLPLVMFDAPCLMRSAATQALDRAGIAWRVVFTSRSLNGVWAAVSAGLGVTVRTD
CCCCCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCEEEEEC
AGLPAGLSLLPPDALPALNPLAVVLHRAEENPSAAIQRLAQIVADRINS
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]