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The map label for this gene is accC2 [H]

Identifier: 157369662

GI number: 157369662

Start: 1548006

End: 1551629

Strand: Direct

Name: accC2 [H]

Synonym: Spro_1419

Alternate gene names: 157369662

Gene position: 1548006-1551629 (Clockwise)

Preceding gene: 157369661

Following gene: 157369663

Centisome position: 28.41

GC content: 62.78

Gene sequence:

>3624_bases
ATGTTTTCTACCGTACTGATTGCCAACCGTGGCGAAATTGCCTGCCGCGCCATCCGCACCCTGAAACGCCTGGGAGTGAC
CAGCGTGGCGGTTTATTCCGACGCCGACCGCAATGCACCGCACGTCACCGCAGCCGATTTGGCGGTGGCGCTGGGCGGTG
AAAAACCCAGCGACAGTTACCTGTGTATCGACAAGATCCTGGCGGCGGCGGCAGAAACCGGCGCGCAGGCGATCTACCCC
GGCTATGGGTTCCTTTCCGAGAGCGCTGAGTTTGCCGACGCCTGCGAAGCGGCGGGCATCGCTTTTATCGGCCCGACGGC
GGCACAAATTCGCGAGTTCGGCCTGAAACACCGGGCGCGTGAGCTGGCGGCGCTGGCGCAGGTGCCGATGACGCCGGGCA
CCGGCCTGCTGGACAACGTTGAGCAGGCGGTCAACGCCGCCAGACAGATTGGCTATCCGGTGATGTTGAAAAGCACCGCC
GGCGGTGGCGGCATTGGCCTGACGCGCTGCGATGACGAAACCGCCCTGCGTGAAGCCTACGACAGCGTGAAACGGCTGGG
TGAGCAGTTCTTCCGCGATTCTGGGGCCTTTATCGAGCGCTTTGTCGATCAGGCCCGTCATGTCGAAGTGCAGATCTTTG
GTGATGGCCAGGGCTGGGTGGTGGCCCTCGGCGAACGCGACTGCTCATTGCAGCGCCGCAACCAGAAAGTGGTGGAAGAG
ACCCCGGCACCGAACCTGCCGACGGCCACCCGTCAGACGCTGCATCAGGCGGCGGTGGCACTGGGGGCGTCGGTTAATTA
TCGCAGCGCCGGCACCGTGGAGTTTATCTACGACGGCGCGCGCGACGAGTTTTATTTCCTCGAAGTGAACACCCGTCTGC
AGGTGGAGCATCCGGTGACTGAAAGTGTGACCGGGCTGGACCTGATCGAATGCATGCTGCAGGTGGCGGCGGGGGATGCG
CTGGACTGGGCGGCGCTGCAACGCCCACCGCAGGGGGCATCGATTGAGGTGCGTATCTATGCCGAAGATCCGCTGAAAAA
CTTCCAGCCCAGCCCGGGCGTACTGACCGAGGTGCATTTCCCTGATGGGGTACGGGTGGACGGTTGGGTCGCCACCGGCA
GTGAAGTGTCGGCATTTTACGACCCGATGATCGCCAAGTTGATTGTTCACGGCGAGGATCGCCGACAGGCGCTGGAGAAA
ATGCGCCTGGCGCTGGATGCCACCCGGCTGCACGGCATCGCGACGAATCTGGATTACCTGCGGCAGGTGATTGCCACCGC
AGAGTTCCAGACCGGTAGCGTGTGGACCCGCATGCTGGACAGTTTCCGCTTCCAGCCCAGCAGTATCGAAGTGCTGCAAC
CGGGCACTTACAGCAGCGTGCAGGATTATCCCGGCCGCGTCGGCTATTGGGATATTGGCGTGCCGCCGTCCGGGCCGATG
GACGACTTTGCTTTCCGGCTGGCCAACCGCATTGTCGGCAATCATCCCAGCGCCGCCGGACTGGAGTTTACCCTGCAGGG
GCCAACCCTGCGTTTCCATTGCGACGCCACTATTGCGCTGACCGGTGCGGACTGCCCGGCAGATTTGGATGGCGAAGCGC
TAAATTACTGGCAGCCGGTGGCGGTTCGGGCCGGGCAGGTACTGACGATGGGCCGCGCCCGGCACGGATGCCGCACCTAT
CTGGCGGTGCGCAATGGTTTTGACGTGCCGGTGTATCTGGGCAGCCGTTCGACCTTTGCCCTGGGGCAGTTTGGCGGTCA
CGCCGGACGGACCCTGCGGGTAGCGGATATGCTGGCGGTGTCGCAACCAGCATTGGCCGCGACCACCACGCCGGCACCGA
TTGCCGCGCCGCAGGCGATGGATGAAAGCCTGATCCCAGAGTACGGCAATCTGTGGAACATCGGCGTGCTGTATGGGCCG
CATGGCGCACCGGACTTCTTTACCCCGGAGTCGATCGACAGTTTCTTTGCCACCGAATGGCAGGTGCATTACAACTCCAA
TCGGTTGGGGGTGCGCCTGTCCGGGCCAAAACCGGAGTGGGCGCGGCAGGACGGCGGCGAGGCAGGGCTGCATCCGTCCA
ACGTACATGACTGCGAATACGCCATCGGTGCCATTAACTTCACCGGCGACTTCCCGGTGATCCTCACCCGTGACGGCCCG
AGCCTCGGTGGTTTCGTCTGCCCGGTGACCATCGCCAGGGCCGAGCTGTGGAAGGTCGGCCAGGTGAAACCAGGCGATCG
CATTCGCTTCCATCCGATTGGTTTCAAACAGGCGCAATCGCTGGAACAGGCGCAGCTTGGCAGTATCGAAGCGCTGGCGG
CGGTGAAGGCCATCACCTTGCCGGCACCGGATCTGACGCCGGGTGCCACGGTTTCTGCCGCTATCCTGGCGGCACTGCCG
GCGACCGACAGCCGCCCGGCAGTGGTCTATCGCCAGGCCGGTGACGGCTACATTTTGCTGGAATATGGCGACAACGTGCT
CAGTCTGGCGCTGCGACTACGCATTCATCTGCTGATGCAGTCGCTCAAGCAGGACGCGATCCCCGGCGTCGAGGAGCTGG
CACCCGGCGTGCGATCGCTGCAGATCCGCTATGACAGCCGCGTTCTGGGCCAGGCCGATTTATTGGCGCGCTTGTTGGCA
CGCGAACAGGCATTGGGCGATGTCAGCCAACTGAAGGTGCCGACGCGCACGGTTTACCTGCCAATGGCGTTTGAAGACTC
CGCCACTCTGGGGGCGGTGGAACGCTATCAACAGACGGTGCGTTCGTCCGCGCCCTGGCTGCCAAACAACGTCGATTTTA
TTCAACGTATCAACGGGCTCAGCACGCGTGAGCAGGTGCGCGACATCATTTTTGATGCCAGTTACCTGATCCTCGGGCTG
GGCGATGTTTACCTCGGCGCACCCTGCGCAGTACCGATTGACCCGCGTCACCGGCTACTCAGTTCCAAATATAACCCGGC
GCGTACCCATACCGCCGAAGGCACGGTCGGCATCGGCGGCATGTACATGTGCATCTATGGCATGGACTCACCGGGGGGCT
ACCAGTTGGTCGGGCGCACGCTGCCGATCTGGAACAAATTCCTCAAAAATCCGCAGTTCAGCGCCGGTGAACCCTGGCTG
CTGCACTTCTTTGATCAGGTGCGTTTCTATCCGGTCAGCGAACAGGAGCTGGATGAGCAGCGCGAGGCGTTCCGCGAAGG
GCGCGCGCAGGTCCGTATTGAGAACAGCGAGTTTGATTTTGCCGAATACAGCCGTTTCCTGGCGGACAACGCCGAAGATA
TCAGTGCCTTCCAGCAGCGCCAGCAGCAGGCGTTCAGCCATGAAGTGACGCGCTGGCAGGAAGAGGAGGGCGAAGCCGAG
GCCCAGTTGCTGCCGCCACAGGATGATGAAGAAGAGGTTGATGGTTATCTGGTCAGCGCCGACCTGAACGGCAGCGTGTG
GAAAATCCTGGTGACGCCGGGGCAGCAGGTCGAAGCCGGCCAGCCACTGATCGTGGTGGAGGCAATGAAAATGGAGCTGG
CGGTCACCGCGCCGCGCGCCGGGATCATCAAACGTATCAGTTGTCAGCAGGGGCGGCCGGTCGGGCCGGGCGACGCCCTG
CTGTGGCTGGAGCACGCCAGTTAA

Upstream 100 bases:

>100_bases
AAGGCTTTATCTGCGAACCCTGGGCGCTGCAGGGGGCCACGGATATCACTGAATTTGGCGGCTGGCGCAATTATGTCGCC
AGCCTGAAGGGGGCTTGATC

Downstream 100 bases:

>100_bases
CCCTGTTTAATCGTCGGGGCGCGGCAGGCTGCGCCCGCAGAGAGGAATGCGATGCAAATCACCAATAACCGCAATAAGGC
ACGGCCGGAGGGGCTGGCGG

Product: Urea carboxylase

Products: NA

Alternate protein names: Acetyl-CoA carboxylase subunit A 2; ACC 2 [H]

Number of amino acids: Translated: 1207; Mature: 1207

Protein sequence:

>1207_residues
MFSTVLIANRGEIACRAIRTLKRLGVTSVAVYSDADRNAPHVTAADLAVALGGEKPSDSYLCIDKILAAAAETGAQAIYP
GYGFLSESAEFADACEAAGIAFIGPTAAQIREFGLKHRARELAALAQVPMTPGTGLLDNVEQAVNAARQIGYPVMLKSTA
GGGGIGLTRCDDETALREAYDSVKRLGEQFFRDSGAFIERFVDQARHVEVQIFGDGQGWVVALGERDCSLQRRNQKVVEE
TPAPNLPTATRQTLHQAAVALGASVNYRSAGTVEFIYDGARDEFYFLEVNTRLQVEHPVTESVTGLDLIECMLQVAAGDA
LDWAALQRPPQGASIEVRIYAEDPLKNFQPSPGVLTEVHFPDGVRVDGWVATGSEVSAFYDPMIAKLIVHGEDRRQALEK
MRLALDATRLHGIATNLDYLRQVIATAEFQTGSVWTRMLDSFRFQPSSIEVLQPGTYSSVQDYPGRVGYWDIGVPPSGPM
DDFAFRLANRIVGNHPSAAGLEFTLQGPTLRFHCDATIALTGADCPADLDGEALNYWQPVAVRAGQVLTMGRARHGCRTY
LAVRNGFDVPVYLGSRSTFALGQFGGHAGRTLRVADMLAVSQPALAATTTPAPIAAPQAMDESLIPEYGNLWNIGVLYGP
HGAPDFFTPESIDSFFATEWQVHYNSNRLGVRLSGPKPEWARQDGGEAGLHPSNVHDCEYAIGAINFTGDFPVILTRDGP
SLGGFVCPVTIARAELWKVGQVKPGDRIRFHPIGFKQAQSLEQAQLGSIEALAAVKAITLPAPDLTPGATVSAAILAALP
ATDSRPAVVYRQAGDGYILLEYGDNVLSLALRLRIHLLMQSLKQDAIPGVEELAPGVRSLQIRYDSRVLGQADLLARLLA
REQALGDVSQLKVPTRTVYLPMAFEDSATLGAVERYQQTVRSSAPWLPNNVDFIQRINGLSTREQVRDIIFDASYLILGL
GDVYLGAPCAVPIDPRHRLLSSKYNPARTHTAEGTVGIGGMYMCIYGMDSPGGYQLVGRTLPIWNKFLKNPQFSAGEPWL
LHFFDQVRFYPVSEQELDEQREAFREGRAQVRIENSEFDFAEYSRFLADNAEDISAFQQRQQQAFSHEVTRWQEEEGEAE
AQLLPPQDDEEEVDGYLVSADLNGSVWKILVTPGQQVEAGQPLIVVEAMKMELAVTAPRAGIIKRISCQQGRPVGPGDAL
LWLEHAS

Sequences:

>Translated_1207_residues
MFSTVLIANRGEIACRAIRTLKRLGVTSVAVYSDADRNAPHVTAADLAVALGGEKPSDSYLCIDKILAAAAETGAQAIYP
GYGFLSESAEFADACEAAGIAFIGPTAAQIREFGLKHRARELAALAQVPMTPGTGLLDNVEQAVNAARQIGYPVMLKSTA
GGGGIGLTRCDDETALREAYDSVKRLGEQFFRDSGAFIERFVDQARHVEVQIFGDGQGWVVALGERDCSLQRRNQKVVEE
TPAPNLPTATRQTLHQAAVALGASVNYRSAGTVEFIYDGARDEFYFLEVNTRLQVEHPVTESVTGLDLIECMLQVAAGDA
LDWAALQRPPQGASIEVRIYAEDPLKNFQPSPGVLTEVHFPDGVRVDGWVATGSEVSAFYDPMIAKLIVHGEDRRQALEK
MRLALDATRLHGIATNLDYLRQVIATAEFQTGSVWTRMLDSFRFQPSSIEVLQPGTYSSVQDYPGRVGYWDIGVPPSGPM
DDFAFRLANRIVGNHPSAAGLEFTLQGPTLRFHCDATIALTGADCPADLDGEALNYWQPVAVRAGQVLTMGRARHGCRTY
LAVRNGFDVPVYLGSRSTFALGQFGGHAGRTLRVADMLAVSQPALAATTTPAPIAAPQAMDESLIPEYGNLWNIGVLYGP
HGAPDFFTPESIDSFFATEWQVHYNSNRLGVRLSGPKPEWARQDGGEAGLHPSNVHDCEYAIGAINFTGDFPVILTRDGP
SLGGFVCPVTIARAELWKVGQVKPGDRIRFHPIGFKQAQSLEQAQLGSIEALAAVKAITLPAPDLTPGATVSAAILAALP
ATDSRPAVVYRQAGDGYILLEYGDNVLSLALRLRIHLLMQSLKQDAIPGVEELAPGVRSLQIRYDSRVLGQADLLARLLA
REQALGDVSQLKVPTRTVYLPMAFEDSATLGAVERYQQTVRSSAPWLPNNVDFIQRINGLSTREQVRDIIFDASYLILGL
GDVYLGAPCAVPIDPRHRLLSSKYNPARTHTAEGTVGIGGMYMCIYGMDSPGGYQLVGRTLPIWNKFLKNPQFSAGEPWL
LHFFDQVRFYPVSEQELDEQREAFREGRAQVRIENSEFDFAEYSRFLADNAEDISAFQQRQQQAFSHEVTRWQEEEGEAE
AQLLPPQDDEEEVDGYLVSADLNGSVWKILVTPGQQVEAGQPLIVVEAMKMELAVTAPRAGIIKRISCQQGRPVGPGDAL
LWLEHAS
>Mature_1207_residues
MFSTVLIANRGEIACRAIRTLKRLGVTSVAVYSDADRNAPHVTAADLAVALGGEKPSDSYLCIDKILAAAAETGAQAIYP
GYGFLSESAEFADACEAAGIAFIGPTAAQIREFGLKHRARELAALAQVPMTPGTGLLDNVEQAVNAARQIGYPVMLKSTA
GGGGIGLTRCDDETALREAYDSVKRLGEQFFRDSGAFIERFVDQARHVEVQIFGDGQGWVVALGERDCSLQRRNQKVVEE
TPAPNLPTATRQTLHQAAVALGASVNYRSAGTVEFIYDGARDEFYFLEVNTRLQVEHPVTESVTGLDLIECMLQVAAGDA
LDWAALQRPPQGASIEVRIYAEDPLKNFQPSPGVLTEVHFPDGVRVDGWVATGSEVSAFYDPMIAKLIVHGEDRRQALEK
MRLALDATRLHGIATNLDYLRQVIATAEFQTGSVWTRMLDSFRFQPSSIEVLQPGTYSSVQDYPGRVGYWDIGVPPSGPM
DDFAFRLANRIVGNHPSAAGLEFTLQGPTLRFHCDATIALTGADCPADLDGEALNYWQPVAVRAGQVLTMGRARHGCRTY
LAVRNGFDVPVYLGSRSTFALGQFGGHAGRTLRVADMLAVSQPALAATTTPAPIAAPQAMDESLIPEYGNLWNIGVLYGP
HGAPDFFTPESIDSFFATEWQVHYNSNRLGVRLSGPKPEWARQDGGEAGLHPSNVHDCEYAIGAINFTGDFPVILTRDGP
SLGGFVCPVTIARAELWKVGQVKPGDRIRFHPIGFKQAQSLEQAQLGSIEALAAVKAITLPAPDLTPGATVSAAILAALP
ATDSRPAVVYRQAGDGYILLEYGDNVLSLALRLRIHLLMQSLKQDAIPGVEELAPGVRSLQIRYDSRVLGQADLLARLLA
REQALGDVSQLKVPTRTVYLPMAFEDSATLGAVERYQQTVRSSAPWLPNNVDFIQRINGLSTREQVRDIIFDASYLILGL
GDVYLGAPCAVPIDPRHRLLSSKYNPARTHTAEGTVGIGGMYMCIYGMDSPGGYQLVGRTLPIWNKFLKNPQFSAGEPWL
LHFFDQVRFYPVSEQELDEQREAFREGRAQVRIENSEFDFAEYSRFLADNAEDISAFQQRQQQAFSHEVTRWQEEEGEAE
AQLLPPQDDEEEVDGYLVSADLNGSVWKILVTPGQQVEAGQPLIVVEAMKMELAVTAPRAGIIKRISCQQGRPVGPGDAL
LWLEHAS

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotin carboxylation domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=439, Percent_Identity=48.0637813211845, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI189095269, Length=444, Percent_Identity=47.0720720720721, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI295821183, Length=444, Percent_Identity=47.0720720720721, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI65506442, Length=444, Percent_Identity=47.0720720720721, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI106049528, Length=537, Percent_Identity=37.0577281191806, Blast_Score=306, Evalue=6e-83,
Organism=Homo sapiens, GI106049295, Length=537, Percent_Identity=37.0577281191806, Blast_Score=306, Evalue=6e-83,
Organism=Homo sapiens, GI106049292, Length=537, Percent_Identity=37.0577281191806, Blast_Score=306, Evalue=6e-83,
Organism=Homo sapiens, GI38679977, Length=521, Percent_Identity=30.9021113243762, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI38679967, Length=521, Percent_Identity=30.9021113243762, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI38679960, Length=521, Percent_Identity=30.9021113243762, Blast_Score=221, Evalue=3e-57,
Organism=Homo sapiens, GI38679971, Length=521, Percent_Identity=30.9021113243762, Blast_Score=221, Evalue=3e-57,
Organism=Homo sapiens, GI38679974, Length=521, Percent_Identity=30.9021113243762, Blast_Score=221, Evalue=3e-57,
Organism=Homo sapiens, GI134142062, Length=506, Percent_Identity=30.8300395256917, Blast_Score=218, Evalue=2e-56,
Organism=Escherichia coli, GI1789654, Length=445, Percent_Identity=42.4719101123596, Blast_Score=335, Evalue=1e-92,
Organism=Escherichia coli, GI1786930, Length=326, Percent_Identity=32.8220858895706, Blast_Score=133, Evalue=9e-32,
Organism=Escherichia coli, GI1786216, Length=281, Percent_Identity=24.9110320284698, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71987519, Length=437, Percent_Identity=47.8260869565217, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17567343, Length=443, Percent_Identity=46.0496613995485, Blast_Score=387, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17562816, Length=458, Percent_Identity=42.1397379912664, Blast_Score=325, Evalue=7e-89,
Organism=Caenorhabditis elegans, GI133931226, Length=486, Percent_Identity=30.8641975308642, Blast_Score=213, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI71997168, Length=448, Percent_Identity=31.25, Blast_Score=194, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71997163, Length=448, Percent_Identity=31.25, Blast_Score=194, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6319685, Length=1210, Percent_Identity=52.0661157024793, Blast_Score=1305, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=449, Percent_Identity=40.7572383073497, Blast_Score=308, Evalue=4e-84,
Organism=Saccharomyces cerevisiae, GI6321376, Length=449, Percent_Identity=41.2026726057906, Blast_Score=297, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6323863, Length=581, Percent_Identity=30.2925989672978, Blast_Score=242, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=29.8828125, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24651757, Length=443, Percent_Identity=44.920993227991, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24651759, Length=404, Percent_Identity=43.5643564356436, Blast_Score=321, Evalue=2e-87,
Organism=Drosophila melanogaster, GI281363050, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24652224, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24652222, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24652220, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24652218, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24652212, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24652210, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24652214, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=3e-85,
Organism=Drosophila melanogaster, GI19921944, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24652216, Length=456, Percent_Identity=40.5701754385965, Blast_Score=314, Evalue=3e-85,
Organism=Drosophila melanogaster, GI161076407, Length=513, Percent_Identity=30.4093567251462, Blast_Score=218, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24586460, Length=513, Percent_Identity=30.4093567251462, Blast_Score=218, Evalue=2e-56,
Organism=Drosophila melanogaster, GI161076409, Length=513, Percent_Identity=30.4093567251462, Blast_Score=218, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24586458, Length=513, Percent_Identity=30.4093567251462, Blast_Score=218, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14; =6.4.1.2 [H]

Molecular weight: Translated: 131508; Mature: 131508

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSTVLIANRGEIACRAIRTLKRLGVTSVAVYSDADRNAPHVTAADLAVALGGEKPSDSY
CCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEHHHEEEEECCCCCCCCC
LCIDKILAAAAETGAQAIYPGYGFLSESAEFADACEAAGIAFIGPTAAQIREFGLKHRAR
HHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHH
ELAALAQVPMTPGTGLLDNVEQAVNAARQIGYPVMLKSTAGGGGIGLTRCDDETALREAY
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEECCCHHHHHHHH
DSVKRLGEQFFRDSGAFIERFVDQARHVEVQIFGDGQGWVVALGERDCSLQRRNQKVVEE
HHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEEEECCCCEEEEECCCCCHHHHHCCHHHHH
TPAPNLPTATRQTLHQAAVALGASVNYRSAGTVEFIYDGARDEFYFLEVNTRLQVEHPVT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCEEEECCCCC
ESVTGLDLIECMLQVAAGDALDWAALQRPPQGASIEVRIYAEDPLKNFQPSPGVLTEVHF
CCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEECCCHHCCCCCCCCEEEEEC
PDGVRVDGWVATGSEVSAFYDPMIAKLIVHGEDRRQALEKMRLALDATRLHGIATNLDYL
CCCCEECEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RQVIATAEFQTGSVWTRMLDSFRFQPSSIEVLQPGTYSSVQDYPGRVGYWDIGVPPSGPM
HHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHCCCCCCCEEECCCCCCCCH
DDFAFRLANRIVGNHPSAAGLEFTLQGPTLRFHCDATIALTGADCPADLDGEALNYWQPV
HHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECEEEEEECCCCCCCCCCCHHCCCCHH
AVRAGQVLTMGRARHGCRTYLAVRNGFDVPVYLGSRSTFALGQFGGHAGRTLRVADMLAV
HHCCCCEEEECHHCCCHHEEEEECCCCCEEEEECCCCEEEEECCCCCCCCEEEHHHHHHH
SQPALAATTTPAPIAAPQAMDESLIPEYGNLWNIGVLYGPHGAPDFFTPESIDSFFATEW
CCCCCEECCCCCCCCCCHHHCHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCEEE
QVHYNSNRLGVRLSGPKPEWARQDGGEAGLHPSNVHDCEYAIGAINFTGDFPVILTRDGP
EEEECCCEEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCC
SLGGFVCPVTIARAELWKVGQVKPGDRIRFHPIGFKQAQSLEQAQLGSIEALAAVKAITL
CCCCEECHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHEEEC
PAPDLTPGATVSAAILAALPATDSRPAVVYRQAGDGYILLEYGDNVLSLALRLRIHLLMQ
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHH
SLKQDAIPGVEELAPGVRSLQIRYDSRVLGQADLLARLLAREQALGDVSQLKVPTRTVYL
HHHHHCCCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCEEEEE
PMAFEDSATLGAVERYQQTVRSSAPWLPNNVDFIQRINGLSTREQVRDIIFDASYLILGL
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCEEEEEC
GDVYLGAPCAVPIDPRHRLLSSKYNPARTHTAEGTVGIGGMYMCIYGMDSPGGYQLVGRT
CHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCC
LPIWNKFLKNPQFSAGEPWLLHFFDQVRFYPVSEQELDEQREAFREGRAQVRIENSEFDF
CHHHHHHHCCCCCCCCCCHHHHHHHHHEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCH
AEYSRFLADNAEDISAFQQRQQQAFSHEVTRWQEEEGEAEAQLLPPQDDEEEVDGYLVSA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHCCEEEEE
DLNGSVWKILVTPGQQVEAGQPLIVVEAMKMELAVTAPRAGIIKRISCQQGRPVGPGDAL
ECCCCEEEEEECCCCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHHHCCCCCCCCCCCEE
LWLEHAS
EEEEECC
>Mature Secondary Structure
MFSTVLIANRGEIACRAIRTLKRLGVTSVAVYSDADRNAPHVTAADLAVALGGEKPSDSY
CCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEHHHEEEEECCCCCCCCC
LCIDKILAAAAETGAQAIYPGYGFLSESAEFADACEAAGIAFIGPTAAQIREFGLKHRAR
HHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHH
ELAALAQVPMTPGTGLLDNVEQAVNAARQIGYPVMLKSTAGGGGIGLTRCDDETALREAY
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEECCCHHHHHHHH
DSVKRLGEQFFRDSGAFIERFVDQARHVEVQIFGDGQGWVVALGERDCSLQRRNQKVVEE
HHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEEEECCCCEEEEECCCCCHHHHHCCHHHHH
TPAPNLPTATRQTLHQAAVALGASVNYRSAGTVEFIYDGARDEFYFLEVNTRLQVEHPVT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCEEEECCCCC
ESVTGLDLIECMLQVAAGDALDWAALQRPPQGASIEVRIYAEDPLKNFQPSPGVLTEVHF
CCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEECCCHHCCCCCCCCEEEEEC
PDGVRVDGWVATGSEVSAFYDPMIAKLIVHGEDRRQALEKMRLALDATRLHGIATNLDYL
CCCCEECEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RQVIATAEFQTGSVWTRMLDSFRFQPSSIEVLQPGTYSSVQDYPGRVGYWDIGVPPSGPM
HHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHCCCCCCCEEECCCCCCCCH
DDFAFRLANRIVGNHPSAAGLEFTLQGPTLRFHCDATIALTGADCPADLDGEALNYWQPV
HHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECEEEEEECCCCCCCCCCCHHCCCCHH
AVRAGQVLTMGRARHGCRTYLAVRNGFDVPVYLGSRSTFALGQFGGHAGRTLRVADMLAV
HHCCCCEEEECHHCCCHHEEEEECCCCCEEEEECCCCEEEEECCCCCCCCEEEHHHHHHH
SQPALAATTTPAPIAAPQAMDESLIPEYGNLWNIGVLYGPHGAPDFFTPESIDSFFATEW
CCCCCEECCCCCCCCCCHHHCHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCEEE
QVHYNSNRLGVRLSGPKPEWARQDGGEAGLHPSNVHDCEYAIGAINFTGDFPVILTRDGP
EEEECCCEEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCC
SLGGFVCPVTIARAELWKVGQVKPGDRIRFHPIGFKQAQSLEQAQLGSIEALAAVKAITL
CCCCEECHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHEEEC
PAPDLTPGATVSAAILAALPATDSRPAVVYRQAGDGYILLEYGDNVLSLALRLRIHLLMQ
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHH
SLKQDAIPGVEELAPGVRSLQIRYDSRVLGQADLLARLLAREQALGDVSQLKVPTRTVYL
HHHHHCCCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCEEEEE
PMAFEDSATLGAVERYQQTVRSSAPWLPNNVDFIQRINGLSTREQVRDIIFDASYLILGL
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCEEEEEC
GDVYLGAPCAVPIDPRHRLLSSKYNPARTHTAEGTVGIGGMYMCIYGMDSPGGYQLVGRT
CHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCC
LPIWNKFLKNPQFSAGEPWLLHFFDQVRFYPVSEQELDEQREAFREGRAQVRIENSEFDF
CHHHHHHHCCCCCCCCCCHHHHHHHHHEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCH
AEYSRFLADNAEDISAFQQRQQQAFSHEVTRWQEEEGEAEAQLLPPQDDEEEVDGYLVSA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHCCEEEEE
DLNGSVWKILVTPGQQVEAGQPLIVVEAMKMELAVTAPRAGIIKRISCQQGRPVGPGDAL
ECCCCEEEEEECCCCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHHHCCCCCCCCCCCEE
LWLEHAS
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]