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The map label for this gene is lsrG [H]

Identifier: 157369626

GI number: 157369626

Start: 1512638

End: 1512931

Strand: Direct

Name: lsrG [H]

Synonym: Spro_1383

Alternate gene names: 157369626

Gene position: 1512638-1512931 (Clockwise)

Preceding gene: 157369618

Following gene: 157369627

Centisome position: 27.76

GC content: 53.06

Gene sequence:

>294_bases
ATGCACGTCACTCTGGTAGAAATTAACGTTAAACAGGACAAAATCGACGAGTTTATTGAGGTCTTCCGCGCCAATCATCT
GGGCGCGATCGAAGAGCCGGGCAATCTGCGTTTTGACGTGTTGCAGGATGAAACCATCCCGACGCGTTTTTATATCTATG
AAGCCTACCGGGACGAGCAGGCCGTCGCCGCCCACAAAAAGACGCCGCACTATCTGCAATGCGTGGAAAAACTGGAGGCG
TTGATGACCGGGCCGCGCAAGAAAACCAGCTTTATCGGCCTGATGCCGGGTTAG

Upstream 100 bases:

>100_bases
GTGCTGCAAAATTGCCGTTGCGGGGGGTAAATCAGCGGGAATAAACCTATGGTTGGAAAGCTATAGGGTATAGACCTTCA
AGGTGAAACAAGGAGCCACC

Downstream 100 bases:

>100_bases
GCCAGTACGCCAGGGTAATTTTATTCAATACATTGCTTACTCTGGCCGTCAGTCTGGCATCTGTGAACTCTTTCTCAGGT
GCTCGTAATGAATATTTATC

Product: autoinducer-2 (AI-2) modifying protein LsrG

Products: NA

Alternate protein names: AI-2-degrading protein lsrG [H]

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MHVTLVEINVKQDKIDEFIEVFRANHLGAIEEPGNLRFDVLQDETIPTRFYIYEAYRDEQAVAAHKKTPHYLQCVEKLEA
LMTGPRKKTSFIGLMPG

Sequences:

>Translated_97_residues
MHVTLVEINVKQDKIDEFIEVFRANHLGAIEEPGNLRFDVLQDETIPTRFYIYEAYRDEQAVAAHKKTPHYLQCVEKLEA
LMTGPRKKTSFIGLMPG
>Mature_97_residues
MHVTLVEINVKQDKIDEFIEVFRANHLGAIEEPGNLRFDVLQDETIPTRFYIYEAYRDEQAVAAHKKTPHYLQCVEKLEA
LMTGPRKKTSFIGLMPG

Specific function: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another

COG id: COG1359

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lsrG family [H]

Homologues:

Organism=Escherichia coli, GI1787797, Length=96, Percent_Identity=75, Blast_Score=155, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007138
- InterPro:   IPR011008 [H]

Pfam domain/function: PF03992 ABM [H]

EC number: NA

Molecular weight: Translated: 11205; Mature: 11205

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVTLVEINVKQDKIDEFIEVFRANHLGAIEEPGNLRFDVLQDETIPTRFYIYEAYRDEQ
CEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCH
AVAAHKKTPHYLQCVEKLEALMTGPRKKTSFIGLMPG
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC
>Mature Secondary Structure
MHVTLVEINVKQDKIDEFIEVFRANHLGAIEEPGNLRFDVLQDETIPTRFYIYEAYRDEQ
CEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCH
AVAAHKKTPHYLQCVEKLEALMTGPRKKTSFIGLMPG
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA