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The map label for this gene is pbpG [H]

Identifier: 157369595

GI number: 157369595

Start: 1482888

End: 1483817

Strand: Direct

Name: pbpG [H]

Synonym: Spro_1352

Alternate gene names: 157369595

Gene position: 1482888-1483817 (Clockwise)

Preceding gene: 157369594

Following gene: 157369596

Centisome position: 27.21

GC content: 56.67

Gene sequence:

>930_bases
ATGCATGTGAAAATACGTGTTTTGGTACTAACCCTGCTCGCTTTGCAGGCAGGAGCAGGCATCGCGCCGCGCGCGCTAGC
CAGCGAAAATAACGCGGTCACCCGTGCCGCCGAGCCTGAACTGGCTTCCGGCAGTGCCATGGTGGTGGATATGCAGACCC
ACAAGGTGATGTATGCGCGTAACCCGGATGAAGTGGTGCCGATCGCTTCGATCACCAAGCTGATGACCGCGATGGTCACG
TTGGACGCCCATCTGCCGCTGGATGAAATGTTGTCGGTGGACATACATCAGACGCCGGAGATGAAAGGGGTCTACTCGCG
CGTTCGTCTGAACAGTGAAATCAGCCGTAAAGATATGCTGCTATTGGCATTGATGTCGTCGGAAAACCGTGCGGCCGCCA
GTCTGGCGCATCATTATCCGGGCGGTTACGGCGCCTTTATCAAAGCGATGAATGCCAAAGCCAAATCGCTGGGGATGACC
AACACGCGTTATGTGGAGCCGACCGGGCTGTCGATTCATAACGTTTCGACCGCGCGCGACCTGACCAAGCTGTTGATTGC
CACCAAGCAATATCCGCTGATTGGCCAGCTCAGCACCACTACCGAACGCATGGCGAGTTTTAAGGATCCGAACTACACGC
TGCCGTTCCGCAACACCAACCATCTGGTATATAACCAGAAATGGAATATCCAGTTGACCAAGACCGGCTTTACCAACGAA
GCGGGACACTGCCTGGCGATGCGTACCATGATCGGTAGCCGTTCGGTCTCGCTGGTGGTGCTGGACGCCTTTGGCAAGTA
CACCCATTTCGCCGATGCCAACCGCCTGCGCACCTGGATCGAAACCGGTAAGGTGACGCCGATCCCCGCGGCGGCCCGTG
ATTACCGCCGTCAGAAAGATGCCCGTCTGGCGAAGAACGAAACCGAATAA

Upstream 100 bases:

>100_bases
GAATTTGTCACAAATCGGCTTGCATAATCCCAGTGCCAACTTCAGATCCCTCACATATAATTCGGCCAAATAAGACCTTC
ATCTTCTTCGTCACAGAGTA

Downstream 100 bases:

>100_bases
CCCGTTCTGCGGCCTGCGGAGTTTTTCTGCAGGCCGCGTCTCTCCCTAAAGCCGCCTTGTCCTTGCCGTCAGCAACATCT
CCAATTACCTTGGGTAGAGC

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MHVKIRVLVLTLLALQAGAGIAPRALASENNAVTRAAEPELASGSAMVVDMQTHKVMYARNPDEVVPIASITKLMTAMVT
LDAHLPLDEMLSVDIHQTPEMKGVYSRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYGAFIKAMNAKAKSLGMT
NTRYVEPTGLSIHNVSTARDLTKLLIATKQYPLIGQLSTTTERMASFKDPNYTLPFRNTNHLVYNQKWNIQLTKTGFTNE
AGHCLAMRTMIGSRSVSLVVLDAFGKYTHFADANRLRTWIETGKVTPIPAAARDYRRQKDARLAKNETE

Sequences:

>Translated_309_residues
MHVKIRVLVLTLLALQAGAGIAPRALASENNAVTRAAEPELASGSAMVVDMQTHKVMYARNPDEVVPIASITKLMTAMVT
LDAHLPLDEMLSVDIHQTPEMKGVYSRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYGAFIKAMNAKAKSLGMT
NTRYVEPTGLSIHNVSTARDLTKLLIATKQYPLIGQLSTTTERMASFKDPNYTLPFRNTNHLVYNQKWNIQLTKTGFTNE
AGHCLAMRTMIGSRSVSLVVLDAFGKYTHFADANRLRTWIETGKVTPIPAAARDYRRQKDARLAKNETE
>Mature_309_residues
MHVKIRVLVLTLLALQAGAGIAPRALASENNAVTRAAEPELASGSAMVVDMQTHKVMYARNPDEVVPIASITKLMTAMVT
LDAHLPLDEMLSVDIHQTPEMKGVYSRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYGAFIKAMNAKAKSLGMT
NTRYVEPTGLSIHNVSTARDLTKLLIATKQYPLIGQLSTTTERMASFKDPNYTLPFRNTNHLVYNQKWNIQLTKTGFTNE
AGHCLAMRTMIGSRSVSLVVLDAFGKYTHFADANRLRTWIETGKVTPIPAAARDYRRQKDARLAKNETE

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=292, Percent_Identity=77.0547945205479, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1787062, Length=287, Percent_Identity=29.9651567944251, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082022, Length=256, Percent_Identity=26.171875, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 34124; Mature: 34124

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVKIRVLVLTLLALQAGAGIAPRALASENNAVTRAAEPELASGSAMVVDMQTHKVMYAR
CEEEEHHHHHHHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCCCCEEEEEEECCEEEEEC
NPDEVVPIASITKLMTAMVTLDAHLPLDEMLSVDIHQTPEMKGVYSRVRLNSEISRKDML
CCCCEECHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHEE
LLALMSSENRAAASLAHHYPGGYGAFIKAMNAKAKSLGMTNTRYVEPTGLSIHNVSTARD
EEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCCEEECCCCCEEECCHHHHH
LTKLLIATKQYPLIGQLSTTTERMASFKDPNYTLPFRNTNHLVYNQKWNIQLTKTGFTNE
HHHHHHHHCCCCCEECCHHHHHHHHHCCCCCEEECCCCCCEEEEECEEEEEEEECCCCCC
AGHCLAMRTMIGSRSVSLVVLDAFGKYTHFADANRLRTWIETGKVTPIPAAARDYRRQKD
CCCCEEEHHHHCCCCEEEEEEECCCCHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ARLAKNETE
HHHHCCCCC
>Mature Secondary Structure
MHVKIRVLVLTLLALQAGAGIAPRALASENNAVTRAAEPELASGSAMVVDMQTHKVMYAR
CEEEEHHHHHHHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCCCCEEEEEEECCEEEEEC
NPDEVVPIASITKLMTAMVTLDAHLPLDEMLSVDIHQTPEMKGVYSRVRLNSEISRKDML
CCCCEECHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHEE
LLALMSSENRAAASLAHHYPGGYGAFIKAMNAKAKSLGMTNTRYVEPTGLSIHNVSTARD
EEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCCEEECCCCCEEECCHHHHH
LTKLLIATKQYPLIGQLSTTTERMASFKDPNYTLPFRNTNHLVYNQKWNIQLTKTGFTNE
HHHHHHHHCCCCCEECCHHHHHHHHHCCCCCEEECCCCCCEEEEECEEEEEEEECCCCCC
AGHCLAMRTMIGSRSVSLVVLDAFGKYTHFADANRLRTWIETGKVTPIPAAARDYRRQKD
CCCCEEEHHHHCCCCEEEEEEECCCCHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ARLAKNETE
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]