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The map label for this gene is fhuA [H]

Identifier: 157369540

GI number: 157369540

Start: 1426693

End: 1428858

Strand: Direct

Name: fhuA [H]

Synonym: Spro_1297

Alternate gene names: 157369540

Gene position: 1426693-1428858 (Clockwise)

Preceding gene: 157369530

Following gene: 157369541

Centisome position: 26.18

GC content: 58.13

Gene sequence:

>2166_bases
ATGAGTGCTGCACGTCGGCGTTTCGTCACGCCCAAAAAACCACCTTATTATTTGGCTTCGGTTTTGTTTTTCAGCCTGTC
GGGTACCGTACAGGCCAGCGCGGATTGCAATAAAACCGGAAACTCACCGCGCTGCGAAGACAACGTTACCGTTGAGGCAT
CAACCCAGCCGCAAAGCCCCTATGGCGGGTTAAATGCCGTCACCCAGACGGCTTCACGCCTGGGCTTGACCCGCCAGGAA
ACGCCGCGCAGTGTCGATGTTATCAGCAAGCAGGCTATTGAGCAGCGTGGGGACCGGACGCTGGCCGAAGTGGTTGAGCA
TGCGCCCGGTATGTCAGGTGTGGCCTCGCCGACGCTCAGCAATGACTTTTCGCTCCGTGGTTTTCGGCCGGTATCCTGGT
TGTATAACGGTGTCGAAACTCCCGGTAGTACCCTCCAGTTAGCGGACCCATCCCACTACGACGGCGTAGAGGTTCTGCGT
GGCCCCGGCTCGGTGCTGAATGGCCTGAGCGCCGCCGGCGGCAGCGTCAATCTGATCTCGCGCCAGCCGACCTTCAGCCG
TCAGCCCGTTGAGCTCGACTACGGGCTGTCTAGTTACAACAGCCAGCGCCTGCACTTTGGCTCCGGGGGAACGCTGTTGG
ATGACGTGGCGGCTTATCGGCTGGATGTTAGCGGTAGCGACAGCGGCACCAATGTGCAATATGAGCGCGACAAACAGAAA
CGGGTGTCCGGCGCCTTGCTGCTTAAGCTGACGGAGAATGCCTTGCTGACGTTGAGCCTGGATCGCATGCTCAACCGCAC
CACCAATCCTTACTACGGCACGCCGCTGGTGGAAGGGCAGATTGCCCGAGAGCTGCGCGATATTAACTACAACAACCTGA
CCGACAGCCGGATCCAGAGTAACGCGACCTCGTTCCAGGCCAGTCTGGATTGGTTCACCACGCCGGAAATCGAGTTGCAT
AACCAGTTCTACTACTACAGTGGTTTTCGTGAGTGGCGCAATGTAGAACGCTTTCGAGCCTCGGCGGCGACTCAGCCCGG
TTACGTCAACCGCGATTCTTTCGGGGCATTGGCCCACGATGATGACCTGATCGGCAACCGCAGCTTCCTGGTGTTCGACC
GGCCGCTGGGCGGTTTTGACAACCGGCTGGTGGTTGGCGTTGATGTGAGCAAACGGCGCTTTCAGTACTACTCCAACGGC
TTTCCCGGCTCTGAAGAGGTGCCTTTGCTGGCTCCGGTCAGAGAAGATTTTTCACAGGGAACGGACCGCCAGCGCACCCC
GGTTCGCCACGTCACGCAAAACCAGTACGCTGGATTTCTGGAAGACCGTTTTAGCCTGACTGACCGCTTAACCCTGCTGG
GGCAGTTACGTTACAACCATATGCAGATGGATTGGCATTTCCAGAGCCCACAAGAGGAAACCCATGAGCACACCTACGTC
TTCAGTGTCTGGAGCCTGGGCCCCAGCTACGCGTTAACCGACAATCTCAATATCTATGCCAACTACACCACCGGCCAGGA
GCCTGGCAACGACCTGTTCTTTTTAAGCCCGGCGCAAACCAGCCTGCCGCTCACCCGGGTACGCCAATGGGAAATCGGTG
CCAAGGGGCAGTTTTGGGATAACAAGGGAGAGGCCACGCTGGCACTGTATGAGCTACGCAAGGACAACCTGTTCGTGCCC
AATGCGCAGCAGCCGGATACGCTGAATGCGGTCGGGCGACAAACTTCGCGCGGCGTAGAGTTAAGCCTGATGCTACGTCC
CAGCTGGCAATGGGAGCTGGCTGCCAATGCGGCCTATACCCACGCCCGCTATGATGAATATCGCGGTGGTAGCCCGGTAG
GCAGCTATAACGGCAACCGTCCGGCTTACATCCCCGACTGGACCGCTAACCTCACCGCACGTTACAAACCGACCCAGCAA
CTGGGGCTCACGTCATCGCTGCGCTACGTGGGCAGCAGTTATAACGACGATGCCAATCAACGCAAAATGCCGGCCTATAC
CACACTCGATCTGGCTGCAGACTACCAGCTCACGCCGGTGGTCGACGTGGGGGTTCGCATCAGAAACGCCACCAATCAAC
TCTATGCTTACCAGCGGACCTACCCGGATCAGGTGCTGATTGCGCCGTCGCGGACTTATGAAAGCTTTATTTCGGTGAGG
TTCTGA

Upstream 100 bases:

>100_bases
AAAACTGGCACCTGATTATTGTTATGTTATAACATAACAAAAAATACAATAACGGTCTTCGGCCGTGCCGGGTTTTTATT
TCACCACAGGGATGCTGTAA

Downstream 100 bases:

>100_bases
TAGCGCCATGCAGCCGATAATTCACCTGCTGCTGGTACTGGGGCTGCTGTTTAGTGCGCTGGTGCAGGCCGGGGCTGTTG
TGTTCAACAACTGTGGCCAA

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 721; Mature: 720

Protein sequence:

>721_residues
MSAARRRFVTPKKPPYYLASVLFFSLSGTVQASADCNKTGNSPRCEDNVTVEASTQPQSPYGGLNAVTQTASRLGLTRQE
TPRSVDVISKQAIEQRGDRTLAEVVEHAPGMSGVASPTLSNDFSLRGFRPVSWLYNGVETPGSTLQLADPSHYDGVEVLR
GPGSVLNGLSAAGGSVNLISRQPTFSRQPVELDYGLSSYNSQRLHFGSGGTLLDDVAAYRLDVSGSDSGTNVQYERDKQK
RVSGALLLKLTENALLTLSLDRMLNRTTNPYYGTPLVEGQIARELRDINYNNLTDSRIQSNATSFQASLDWFTTPEIELH
NQFYYYSGFREWRNVERFRASAATQPGYVNRDSFGALAHDDDLIGNRSFLVFDRPLGGFDNRLVVGVDVSKRRFQYYSNG
FPGSEEVPLLAPVREDFSQGTDRQRTPVRHVTQNQYAGFLEDRFSLTDRLTLLGQLRYNHMQMDWHFQSPQEETHEHTYV
FSVWSLGPSYALTDNLNIYANYTTGQEPGNDLFFLSPAQTSLPLTRVRQWEIGAKGQFWDNKGEATLALYELRKDNLFVP
NAQQPDTLNAVGRQTSRGVELSLMLRPSWQWELAANAAYTHARYDEYRGGSPVGSYNGNRPAYIPDWTANLTARYKPTQQ
LGLTSSLRYVGSSYNDDANQRKMPAYTTLDLAADYQLTPVVDVGVRIRNATNQLYAYQRTYPDQVLIAPSRTYESFISVR
F

Sequences:

>Translated_721_residues
MSAARRRFVTPKKPPYYLASVLFFSLSGTVQASADCNKTGNSPRCEDNVTVEASTQPQSPYGGLNAVTQTASRLGLTRQE
TPRSVDVISKQAIEQRGDRTLAEVVEHAPGMSGVASPTLSNDFSLRGFRPVSWLYNGVETPGSTLQLADPSHYDGVEVLR
GPGSVLNGLSAAGGSVNLISRQPTFSRQPVELDYGLSSYNSQRLHFGSGGTLLDDVAAYRLDVSGSDSGTNVQYERDKQK
RVSGALLLKLTENALLTLSLDRMLNRTTNPYYGTPLVEGQIARELRDINYNNLTDSRIQSNATSFQASLDWFTTPEIELH
NQFYYYSGFREWRNVERFRASAATQPGYVNRDSFGALAHDDDLIGNRSFLVFDRPLGGFDNRLVVGVDVSKRRFQYYSNG
FPGSEEVPLLAPVREDFSQGTDRQRTPVRHVTQNQYAGFLEDRFSLTDRLTLLGQLRYNHMQMDWHFQSPQEETHEHTYV
FSVWSLGPSYALTDNLNIYANYTTGQEPGNDLFFLSPAQTSLPLTRVRQWEIGAKGQFWDNKGEATLALYELRKDNLFVP
NAQQPDTLNAVGRQTSRGVELSLMLRPSWQWELAANAAYTHARYDEYRGGSPVGSYNGNRPAYIPDWTANLTARYKPTQQ
LGLTSSLRYVGSSYNDDANQRKMPAYTTLDLAADYQLTPVVDVGVRIRNATNQLYAYQRTYPDQVLIAPSRTYESFISVR
F
>Mature_720_residues
SAARRRFVTPKKPPYYLASVLFFSLSGTVQASADCNKTGNSPRCEDNVTVEASTQPQSPYGGLNAVTQTASRLGLTRQET
PRSVDVISKQAIEQRGDRTLAEVVEHAPGMSGVASPTLSNDFSLRGFRPVSWLYNGVETPGSTLQLADPSHYDGVEVLRG
PGSVLNGLSAAGGSVNLISRQPTFSRQPVELDYGLSSYNSQRLHFGSGGTLLDDVAAYRLDVSGSDSGTNVQYERDKQKR
VSGALLLKLTENALLTLSLDRMLNRTTNPYYGTPLVEGQIARELRDINYNNLTDSRIQSNATSFQASLDWFTTPEIELHN
QFYYYSGFREWRNVERFRASAATQPGYVNRDSFGALAHDDDLIGNRSFLVFDRPLGGFDNRLVVGVDVSKRRFQYYSNGF
PGSEEVPLLAPVREDFSQGTDRQRTPVRHVTQNQYAGFLEDRFSLTDRLTLLGQLRYNHMQMDWHFQSPQEETHEHTYVF
SVWSLGPSYALTDNLNIYANYTTGQEPGNDLFFLSPAQTSLPLTRVRQWEIGAKGQFWDNKGEATLALYELRKDNLFVPN
AQQPDTLNAVGRQTSRGVELSLMLRPSWQWELAANAAYTHARYDEYRGGSPVGSYNGNRPAYIPDWTANLTARYKPTQQL
GLTSSLRYVGSSYNDDANQRKMPAYTTLDLAADYQLTPVVDVGVRIRNATNQLYAYQRTYPDQVLIAPSRTYESFISVRF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=751, Percent_Identity=25.832223701731, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1787344, Length=601, Percent_Identity=23.2945091514143, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80804; Mature: 80673

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAARRRFVTPKKPPYYLASVLFFSLSGTVQASADCNKTGNSPRCEDNVTVEASTQPQSP
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCCC
YGGLNAVTQTASRLGLTRQETPRSVDVISKQAIEQRGDRTLAEVVEHAPGMSGVASPTLS
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
NDFSLRGFRPVSWLYNGVETPGSTLQLADPSHYDGVEVLRGPGSVLNGLSAAGGSVNLIS
CCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCCHHEECCCCHHHHHHHCCCCCEEEEE
RQPTFSRQPVELDYGLSSYNSQRLHFGSGGTLLDDVAAYRLDVSGSDSGTNVQYERDKQK
CCCCCCCCCEEEECCCCCCCCCEEEECCCCCHHHHHEEEEEEECCCCCCCCEEECCCHHH
RVSGALLLKLTENALLTLSLDRMLNRTTNPYYGTPLVEGQIARELRDINYNNLTDSRIQS
HCCCEEEEEEECCEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHC
NATSFQASLDWFTTPEIELHNQFYYYSGFREWRNVERFRASAATQPGYVNRDSFGALAHD
CCCCEEEECCCCCCCCEEECCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DDLIGNRSFLVFDRPLGGFDNRLVVGVDVSKRRFQYYSNGFPGSEEVPLLAPVREDFSQG
CCCCCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCEECHHHHHHHCC
TDRQRTPVRHVTQNQYAGFLEDRFSLTDRLTLLGQLRYNHMQMDWHFQSPQEETHEHTYV
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHCCCEEEE
FSVWSLGPSYALTDNLNIYANYTTGQEPGNDLFFLSPAQTSLPLTRVRQWEIGAKGQFWD
EEEECCCCCEEEECCCEEEEEECCCCCCCCCEEEECCCCCCCCHHHHEEEECCCCCCCCC
NKGEATLALYELRKDNLFVPNAQQPDTLNAVGRQTSRGVELSLMLRPSWQWELAANAAYT
CCCCEEEEEEEECCCCEECCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCHH
HARYDEYRGGSPVGSYNGNRPAYIPDWTANLTARYKPTQQLGLTSSLRYVGSSYNDDANQ
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHCCHHHHHHHCCCCCCCCCC
RKMPAYTTLDLAADYQLTPVVDVGVRIRNATNQLYAYQRTYPDQVLIAPSRTYESFISVR
CCCCCEEEEEEECCCEECEEEEECEEEECCCCCEEEEECCCCCEEEEECCCCHHHHHEEC
F
C
>Mature Secondary Structure 
SAARRRFVTPKKPPYYLASVLFFSLSGTVQASADCNKTGNSPRCEDNVTVEASTQPQSP
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCCC
YGGLNAVTQTASRLGLTRQETPRSVDVISKQAIEQRGDRTLAEVVEHAPGMSGVASPTLS
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
NDFSLRGFRPVSWLYNGVETPGSTLQLADPSHYDGVEVLRGPGSVLNGLSAAGGSVNLIS
CCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCCHHEECCCCHHHHHHHCCCCCEEEEE
RQPTFSRQPVELDYGLSSYNSQRLHFGSGGTLLDDVAAYRLDVSGSDSGTNVQYERDKQK
CCCCCCCCCEEEECCCCCCCCCEEEECCCCCHHHHHEEEEEEECCCCCCCCEEECCCHHH
RVSGALLLKLTENALLTLSLDRMLNRTTNPYYGTPLVEGQIARELRDINYNNLTDSRIQS
HCCCEEEEEEECCEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHC
NATSFQASLDWFTTPEIELHNQFYYYSGFREWRNVERFRASAATQPGYVNRDSFGALAHD
CCCCEEEECCCCCCCCEEECCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DDLIGNRSFLVFDRPLGGFDNRLVVGVDVSKRRFQYYSNGFPGSEEVPLLAPVREDFSQG
CCCCCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCEECHHHHHHHCC
TDRQRTPVRHVTQNQYAGFLEDRFSLTDRLTLLGQLRYNHMQMDWHFQSPQEETHEHTYV
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHCCCEEEE
FSVWSLGPSYALTDNLNIYANYTTGQEPGNDLFFLSPAQTSLPLTRVRQWEIGAKGQFWD
EEEECCCCCEEEECCCEEEEEECCCCCCCCCEEEECCCCCCCCHHHHEEEECCCCCCCCC
NKGEATLALYELRKDNLFVPNAQQPDTLNAVGRQTSRGVELSLMLRPSWQWELAANAAYT
CCCCEEEEEEEECCCCEECCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCHH
HARYDEYRGGSPVGSYNGNRPAYIPDWTANLTARYKPTQQLGLTSSLRYVGSSYNDDANQ
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHCCHHHHHHHCCCCCCCCCC
RKMPAYTTLDLAADYQLTPVVDVGVRIRNATNQLYAYQRTYPDQVLIAPSRTYESFISVR
CCCCCEEEEEEECCCEECEEEEECEEEECCCCCEEEEECCCCCEEEEECCCCHHHHHEEC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]