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The map label for this gene is galE [H]

Identifier: 157369477

GI number: 157369477

Start: 1358257

End: 1359309

Strand: Direct

Name: galE [H]

Synonym: Spro_1234

Alternate gene names: 157369477

Gene position: 1358257-1359309 (Clockwise)

Preceding gene: 157369476

Following gene: 157369478

Centisome position: 24.93

GC content: 51.95

Gene sequence:

>1053_bases
ATGGCTATATTGGTGACGGGCGGCGCCGGTTATATCGGCTCGCATACGGTGTTGGCACTGTTGGAAAGGGGGGAGGAAGT
TGTCGTACTGGACAACCTGTCCAACAGTTCGTCAGAGTCTTTGTTTCGGGTCGAGCGATTAACCGGTAAAAAAGTGAATT
TTTATCATGGAGATATCCAGCAACACCATTTGTTGGATCATATATTTCGTCAGCATGATGTTCATGCGGTTATTCATCTT
GCGGGGTTGAAATCGGTCAGGGAATCTACCGAAGAACCGCTGAAATATTATCAAAATAATATTTCCGGCTCATTGATCGT
ACTGGACAGAATGCGCCATGCCGGCGTTAAGCAATTTATTTTCAGCTCTTCAGCCACCGTCTACGGACCGGCGGAATATA
CCCCGCTGACGGAGAATTGCCGTGTTGGGCAGACCACCAATCCTTATGGAACTTCCAAGCTGATTGTCGAGCAGATCCTC
GCGGAGTTTGCTTCCACGGCCCCGCAGATGGCGATCACCGCGCTGCGTTACTTTAATCCGGCCGGGGCGCACGAGTCCGG
CTTGATTGGTGAGGATCCCGCCGGCATTCCCAATAATCTTCTGGCTTATCTGGCGCAGGTGGCTATTGGCAAACTCGCGG
TGTTGCCGGTGTATGGCAACGACTACCCTACCAGCGATGGTACCGGGGTACGTGATTACATTCACGTTATGGATTTGGCC
GAAGGGCATTTGAAAGCGCTGGATAACCTGCAGCCAGGTTTTAACGTCTATAACCTGGGCACCGGCAAAGGCTACTCGGT
GCTGGAGATTATTCGGGCGTTTGAACGCGCCTGTGGCTTCAAAATCGCCTACCAATTTAATCCCCGGCGTGCGGGAGATA
TTGCCGAGTGTTGGTCCGACCCATCGTTGGCGGCAGAAAAGCTGGGCTGGCAAGCTAAACGCAGTCTGGAAAAAATGGTG
TGTGATGCCTGGTCATGGCAAAGCAAAAATCCGCAGGGTTACAGCCGTTGTGCATCGATGCCATCGATGAGGATGCTGGC
CGATGAAGCTTAA

Upstream 100 bases:

>100_bases
TTACTGCTTTGTATTGCTTTACCTGTCGGTTTTAAAACCCGGGAAGTTTAGGTGGTTTCTGAGTGAATCGTTTATTTTTA
AGCATAAACAAGGAAATATG

Downstream 100 bases:

>100_bases
CGACGGGCATTTGGGTGTTCTGCAGGATGATCTGTTCCGGGCAGAATACGAAGCGCGGATCAGCGAGCTGAAGTTTGAGT
TCGCTAAATATCAGCGCCAG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MAILVTGGAGYIGSHTVLALLERGEEVVVLDNLSNSSSESLFRVERLTGKKVNFYHGDIQQHHLLDHIFRQHDVHAVIHL
AGLKSVRESTEEPLKYYQNNISGSLIVLDRMRHAGVKQFIFSSSATVYGPAEYTPLTENCRVGQTTNPYGTSKLIVEQIL
AEFASTAPQMAITALRYFNPAGAHESGLIGEDPAGIPNNLLAYLAQVAIGKLAVLPVYGNDYPTSDGTGVRDYIHVMDLA
EGHLKALDNLQPGFNVYNLGTGKGYSVLEIIRAFERACGFKIAYQFNPRRAGDIAECWSDPSLAAEKLGWQAKRSLEKMV
CDAWSWQSKNPQGYSRCASMPSMRMLADEA

Sequences:

>Translated_350_residues
MAILVTGGAGYIGSHTVLALLERGEEVVVLDNLSNSSSESLFRVERLTGKKVNFYHGDIQQHHLLDHIFRQHDVHAVIHL
AGLKSVRESTEEPLKYYQNNISGSLIVLDRMRHAGVKQFIFSSSATVYGPAEYTPLTENCRVGQTTNPYGTSKLIVEQIL
AEFASTAPQMAITALRYFNPAGAHESGLIGEDPAGIPNNLLAYLAQVAIGKLAVLPVYGNDYPTSDGTGVRDYIHVMDLA
EGHLKALDNLQPGFNVYNLGTGKGYSVLEIIRAFERACGFKIAYQFNPRRAGDIAECWSDPSLAAEKLGWQAKRSLEKMV
CDAWSWQSKNPQGYSRCASMPSMRMLADEA
>Mature_349_residues
AILVTGGAGYIGSHTVLALLERGEEVVVLDNLSNSSSESLFRVERLTGKKVNFYHGDIQQHHLLDHIFRQHDVHAVIHLA
GLKSVRESTEEPLKYYQNNISGSLIVLDRMRHAGVKQFIFSSSATVYGPAEYTPLTENCRVGQTTNPYGTSKLIVEQILA
EFASTAPQMAITALRYFNPAGAHESGLIGEDPAGIPNNLLAYLAQVAIGKLAVLPVYGNDYPTSDGTGVRDYIHVMDLAE
GHLKALDNLQPGFNVYNLGTGKGYSVLEIIRAFERACGFKIAYQFNPRRAGDIAECWSDPSLAAEKLGWQAKRSLEKMVC
DAWSWQSKNPQGYSRCASMPSMRMLADEA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=53.2352941176471, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=53.2352941176471, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=53.2352941176471, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI7657641, Length=273, Percent_Identity=24.9084249084249, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI42516563, Length=339, Percent_Identity=25.9587020648968, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=53.5714285714286, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1788353, Length=364, Percent_Identity=23.9010989010989, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788366, Length=357, Percent_Identity=22.96918767507, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI48994969, Length=367, Percent_Identity=26.158038147139, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=51.4450867052023, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=51.1494252873563, Blast_Score=358, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17568069, Length=279, Percent_Identity=23.2974910394265, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=47.9651162790698, Blast_Score=324, Evalue=1e-89,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=52.4781341107872, Blast_Score=380, Evalue=1e-106,
Organism=Drosophila melanogaster, GI21356223, Length=329, Percent_Identity=26.1398176291793, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38467; Mature: 38336

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVTGGAGYIGSHTVLALLERGEEVVVLDNLSNSSSESLFRVERLTGKKVNFYHGDIQ
CEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCH
QHHLLDHIFRQHDVHAVIHLAGLKSVRESTEEPLKYYQNNISGSLIVLDRMRHAGVKQFI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
FSSSATVYGPAEYTPLTENCRVGQTTNPYGTSKLIVEQILAEFASTAPQMAITALRYFNP
HCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
AGAHESGLIGEDPAGIPNNLLAYLAQVAIGKLAVLPVYGNDYPTSDGTGVRDYIHVMDLA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
EGHLKALDNLQPGFNVYNLGTGKGYSVLEIIRAFERACGFKIAYQFNPRRAGDIAECWSD
HHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHCCC
PSLAAEKLGWQAKRSLEKMVCDAWSWQSKNPQGYSRCASMPSMRMLADEA
HHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure 
AILVTGGAGYIGSHTVLALLERGEEVVVLDNLSNSSSESLFRVERLTGKKVNFYHGDIQ
EEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCH
QHHLLDHIFRQHDVHAVIHLAGLKSVRESTEEPLKYYQNNISGSLIVLDRMRHAGVKQFI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
FSSSATVYGPAEYTPLTENCRVGQTTNPYGTSKLIVEQILAEFASTAPQMAITALRYFNP
HCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
AGAHESGLIGEDPAGIPNNLLAYLAQVAIGKLAVLPVYGNDYPTSDGTGVRDYIHVMDLA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
EGHLKALDNLQPGFNVYNLGTGKGYSVLEIIRAFERACGFKIAYQFNPRRAGDIAECWSD
HHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHCCC
PSLAAEKLGWQAKRSLEKMVCDAWSWQSKNPQGYSRCASMPSMRMLADEA
HHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7507102 [H]