Click here to switch to the map view.

The map label for this gene is adrA [H]

Identifier: 157369436

GI number: 157369436

Start: 1310186

End: 1311247

Strand: Reverse

Name: adrA [H]

Synonym: Spro_1193

Alternate gene names: 157369436

Gene position: 1311247-1310186 (Counterclockwise)

Preceding gene: 157369438

Following gene: 157369435

Centisome position: 24.06

GC content: 55.65

Gene sequence:

>1062_bases
ATGTATACGCCATCAGTGATTGATACCAGACGTTCCGGCCTTAGCTTCGCCAGACGCACTTATCTGCCACGTGTCGTCGG
CCTGGGGATCGGCTTTATCTGCGTGTTCTCAGTATTCTATACGCAAAAAACCTCATACTGGGTCTGGGGCCTGCTGATTT
TCCACGGTTTTATCTGGCCACACCTTGCCTATCAATGGGCGCGCCGTTCCGCCATGCCCTTCAAGGCTGAAATTCGCAAC
CTGCTGATCGATTCGTTTTTCGGCGGGTTGTGGGTAGCCATGATGGCATTCAATGCCTTACCGTCAGTCGTTATCCTGTC
GATGATGGGCATGAATAACATGGCTTCTGCCGGCAAATCTCTGTTCTTTAAAGGGTTGGCGGTACAAGTACTCAGCGCCC
TGGCAATCAGCGCTCTGCTGGGCTTCCCTTTCCAACCGCAAAGCACACCGCTGCAGATCTATCTGTGCCTGCCGATGATC
TATTTCTACCCTATCCTATTGGGATTAGTGACCTACCGCACCGCCAAACGGCTGGCGGAAAAAAAACAGGAGTTGTTGCG
CATCAGCATGCGCGACGGCCTGACCGGGCTGTACAACCGCCGCCATTGGGAACATTTGCTGCATCACCAATTTGACAGCT
GCCGCCGCTATCAGCACAGCGCGACGCTGATCCTGATGGATATCGACCACTTTAAAACCATTAACGACACCTTCGGCCAT
GCGCTGGGTGACGAGGCGCTGGCGGTACTGGCAGAGGAATTGCTAATCGGTTTGCGCGCCGTGGATATTGTCGGACGCTA
CGGTGGCGACGAATTTGGGGCCGTGTTGCCCAACACCAGCGCCGAACAGGCCAGCATAGCGCTGTTGCGCATTCAGGAAC
GGTTGAACGAGATTGTTTTCCGCGAAGCGCCGCAGCTACGGCTGAACATCAGCGCCGGCATTGCGGATTATCACGGCGAC
ATGAGCGGCTATCTGGACTGGTTAAAAGCCGCCGACAACGCGCTGTACCGGGCGAAGAACAACGGTCGCAATCGCCTGGA
GCTGGCGGTACCCGGCCACTGA

Upstream 100 bases:

>100_bases
CGCCAATATGCAACTTTAAATCGGCTGGTTACGCTTCAGACTATTCTGAGTTTTTAACCCGCATGATACGCTGTTCCCCT
GCTCATCATGGAGTTGCCGG

Downstream 100 bases:

>100_bases
GACCGGAGGAAAAATTTCAGTTTCCAGTCACTTTTGATACTACAAAATAGGCAGCGCCGGGTGTAAGATCCCGTCTGCGC
GGCAAACAGCGGCGTCGAAC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MYTPSVIDTRRSGLSFARRTYLPRVVGLGIGFICVFSVFYTQKTSYWVWGLLIFHGFIWPHLAYQWARRSAMPFKAEIRN
LLIDSFFGGLWVAMMAFNALPSVVILSMMGMNNMASAGKSLFFKGLAVQVLSALAISALLGFPFQPQSTPLQIYLCLPMI
YFYPILLGLVTYRTAKRLAEKKQELLRISMRDGLTGLYNRRHWEHLLHHQFDSCRRYQHSATLILMDIDHFKTINDTFGH
ALGDEALAVLAEELLIGLRAVDIVGRYGGDEFGAVLPNTSAEQASIALLRIQERLNEIVFREAPQLRLNISAGIADYHGD
MSGYLDWLKAADNALYRAKNNGRNRLELAVPGH

Sequences:

>Translated_353_residues
MYTPSVIDTRRSGLSFARRTYLPRVVGLGIGFICVFSVFYTQKTSYWVWGLLIFHGFIWPHLAYQWARRSAMPFKAEIRN
LLIDSFFGGLWVAMMAFNALPSVVILSMMGMNNMASAGKSLFFKGLAVQVLSALAISALLGFPFQPQSTPLQIYLCLPMI
YFYPILLGLVTYRTAKRLAEKKQELLRISMRDGLTGLYNRRHWEHLLHHQFDSCRRYQHSATLILMDIDHFKTINDTFGH
ALGDEALAVLAEELLIGLRAVDIVGRYGGDEFGAVLPNTSAEQASIALLRIQERLNEIVFREAPQLRLNISAGIADYHGD
MSGYLDWLKAADNALYRAKNNGRNRLELAVPGH
>Mature_353_residues
MYTPSVIDTRRSGLSFARRTYLPRVVGLGIGFICVFSVFYTQKTSYWVWGLLIFHGFIWPHLAYQWARRSAMPFKAEIRN
LLIDSFFGGLWVAMMAFNALPSVVILSMMGMNNMASAGKSLFFKGLAVQVLSALAISALLGFPFQPQSTPLQIYLCLPMI
YFYPILLGLVTYRTAKRLAEKKQELLRISMRDGLTGLYNRRHWEHLLHHQFDSCRRYQHSATLILMDIDHFKTINDTFGH
ALGDEALAVLAEELLIGLRAVDIVGRYGGDEFGAVLPNTSAEQASIALLRIQERLNEIVFREAPQLRLNISAGIADYHGD
MSGYLDWLKAADNALYRAKNNGRNRLELAVPGH

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=342, Percent_Identity=47.6608187134503, Blast_Score=339, Evalue=1e-94,
Organism=Escherichia coli, GI87081881, Length=202, Percent_Identity=36.1386138613861, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=38.6075949367089, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=33.1288343558282, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788381, Length=161, Percent_Identity=36.0248447204969, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=36.4779874213836, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081974, Length=163, Percent_Identity=34.3558282208589, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787802, Length=182, Percent_Identity=31.3186813186813, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787816, Length=188, Percent_Identity=34.0425531914894, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787541, Length=175, Percent_Identity=32.5714285714286, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87081977, Length=182, Percent_Identity=32.967032967033, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787056, Length=127, Percent_Identity=40.1574803149606, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788085, Length=168, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788956, Length=108, Percent_Identity=40.7407407407407, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 39897; Mature: 39897

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTPSVIDTRRSGLSFARRTYLPRVVGLGIGFICVFSVFYTQKTSYWVWGLLIFHGFIWP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
HLAYQWARRSAMPFKAEIRNLLIDSFFGGLWVAMMAFNALPSVVILSMMGMNNMASAGKS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LFFKGLAVQVLSALAISALLGFPFQPQSTPLQIYLCLPMIYFYPILLGLVTYRTAKRLAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQELLRISMRDGLTGLYNRRHWEHLLHHQFDSCRRYQHSATLILMDIDHFKTINDTFGH
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHH
ALGDEALAVLAEELLIGLRAVDIVGRYGGDEFGAVLPNTSAEQASIALLRIQERLNEIVF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
REAPQLRLNISAGIADYHGDMSGYLDWLKAADNALYRAKNNGRNRLELAVPGH
CCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
>Mature Secondary Structure
MYTPSVIDTRRSGLSFARRTYLPRVVGLGIGFICVFSVFYTQKTSYWVWGLLIFHGFIWP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
HLAYQWARRSAMPFKAEIRNLLIDSFFGGLWVAMMAFNALPSVVILSMMGMNNMASAGKS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LFFKGLAVQVLSALAISALLGFPFQPQSTPLQIYLCLPMIYFYPILLGLVTYRTAKRLAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQELLRISMRDGLTGLYNRRHWEHLLHHQFDSCRRYQHSATLILMDIDHFKTINDTFGH
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHH
ALGDEALAVLAEELLIGLRAVDIVGRYGGDEFGAVLPNTSAEQASIALLRIQERLNEIVF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
REAPQLRLNISAGIADYHGDMSGYLDWLKAADNALYRAKNNGRNRLELAVPGH
CCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]