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The map label for this gene is yrpG [H]

Identifier: 157369421

GI number: 157369421

Start: 1295472

End: 1296533

Strand: Reverse

Name: yrpG [H]

Synonym: Spro_1178

Alternate gene names: 157369421

Gene position: 1296533-1295472 (Counterclockwise)

Preceding gene: 157369425

Following gene: 157369419

Centisome position: 23.79

GC content: 57.44

Gene sequence:

>1062_bases
ATGCTGACATCACTGGCCCTGAACCATTACCGCCTGCTTGGCCGCTCTGGCCTGCGCGTTTCGCCGCTGGCGCTCGGCAC
CATGACCTTTGGCACCGATTGGGGCTGGGGCGCAGAACAAGCGGAAGCTCGTCGGCTGTTTGACGTTTATGTAGAACGTG
GCGGCAATTTTATTGATACCGCCAACCGCTATACCGAAGGCAGTTCCGAACGATTTATTGGAGAATTCGCCACCGGACGC
CGCGACCGTCTGGTGATCGCCACCAAATACACGCTACCCATGCAGCCCGATAATCCAAACTCTGGCGGCAACCACCGTAA
AAGCATGGTGCGTTCGGTGGAAGAAAGCCTGCGACGCCTGAACACCGATTATATCGACCTGCTGTATCTGCACGCCTGGG
ACGCCACCACCCCGACGGAAGAGATCATGCGCGCCATGGACGATCTGGTGCGTGCCGGCAAAGTGTTGTATCTGGCCGTT
TCGGATCTGCCAGCCTGGCAGGCCGCCAGAATGCAGACACTGGCGGATTTACGCGGTTGGTCACCGTTGATTGGCCTGCA
GATTGAATACAGCCTGTTGGAACGTACCGTGGAGCGAGAACTGATACCGATGGCGCAAGAGCTGGGCCTTGGCGTCATTC
CATGGTCACCGCTTTCCGGTGGCATATTGAGCGGAAAATACAGTCGGCAGGATTTGCAGGTGCAGGAGGAAGAGAACGGT
ACCCGACGTGCCATGGTTCGCGACAAGGGTATGCTGACCGAGCGCAATATTACCATTGCCGAAACGGTATTGACGCTGGC
CAGGGAGACGGATTTTAGCCCTTCTCAGGTAGCCCTGGCCTGGACGCTGCGTAACCCGGCAGTGACGGCCCCGATCATCG
GTGCACGCACGTTGGCACAACTGGAAGATAACCTGGGAGCGCTGGAGGTCAGGCTGACAGAAGAGCAGTGGCGGCGTTTG
GATACGGCAAGCGCCATTGAACTGGGTTTCCCCCATGATTTTCTGGCGCTACAAGTTACGCGCGACATTATGTTTGGCGG
TTTGACGATTGAGCGCAGATAA

Upstream 100 bases:

>100_bases
CATTATGCCCCCTACACTTAATAATTCATGAAGATTATAGCGTATTCATTACACTCCCGGTGGGGCCTATGCTTGAACAA
AACCATAGAGGAAATACCCC

Downstream 100 bases:

>100_bases
AAAAAATCCCGCACGAGGCGGGATAAACTTAACAGGGATGGGGTAATACACTACAGGGAATGGATAACACACAACATCAT
CGGGTAGGACTACACTATCA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLTSLALNHYRLLGRSGLRVSPLALGTMTFGTDWGWGAEQAEARRLFDVYVERGGNFIDTANRYTEGSSERFIGEFATGR
RDRLVIATKYTLPMQPDNPNSGGNHRKSMVRSVEESLRRLNTDYIDLLYLHAWDATTPTEEIMRAMDDLVRAGKVLYLAV
SDLPAWQAARMQTLADLRGWSPLIGLQIEYSLLERTVERELIPMAQELGLGVIPWSPLSGGILSGKYSRQDLQVQEEENG
TRRAMVRDKGMLTERNITIAETVLTLARETDFSPSQVALAWTLRNPAVTAPIIGARTLAQLEDNLGALEVRLTEEQWRRL
DTASAIELGFPHDFLALQVTRDIMFGGLTIERR

Sequences:

>Translated_353_residues
MLTSLALNHYRLLGRSGLRVSPLALGTMTFGTDWGWGAEQAEARRLFDVYVERGGNFIDTANRYTEGSSERFIGEFATGR
RDRLVIATKYTLPMQPDNPNSGGNHRKSMVRSVEESLRRLNTDYIDLLYLHAWDATTPTEEIMRAMDDLVRAGKVLYLAV
SDLPAWQAARMQTLADLRGWSPLIGLQIEYSLLERTVERELIPMAQELGLGVIPWSPLSGGILSGKYSRQDLQVQEEENG
TRRAMVRDKGMLTERNITIAETVLTLARETDFSPSQVALAWTLRNPAVTAPIIGARTLAQLEDNLGALEVRLTEEQWRRL
DTASAIELGFPHDFLALQVTRDIMFGGLTIERR
>Mature_353_residues
MLTSLALNHYRLLGRSGLRVSPLALGTMTFGTDWGWGAEQAEARRLFDVYVERGGNFIDTANRYTEGSSERFIGEFATGR
RDRLVIATKYTLPMQPDNPNSGGNHRKSMVRSVEESLRRLNTDYIDLLYLHAWDATTPTEEIMRAMDDLVRAGKVLYLAV
SDLPAWQAARMQTLADLRGWSPLIGLQIEYSLLERTVERELIPMAQELGLGVIPWSPLSGGILSGKYSRQDLQVQEEENG
TRRAMVRDKGMLTERNITIAETVLTLARETDFSPSQVALAWTLRNPAVTAPIIGARTLAQLEDNLGALEVRLTEEQWRRL
DTASAIELGFPHDFLALQVTRDIMFGGLTIERR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=318, Percent_Identity=34.9056603773585, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI27436962, Length=318, Percent_Identity=34.5911949685535, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI27436966, Length=318, Percent_Identity=34.5911949685535, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI4504825, Length=316, Percent_Identity=32.9113924050633, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI27436969, Length=313, Percent_Identity=32.9073482428115, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI27436971, Length=321, Percent_Identity=31.1526479750779, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI223718702, Length=278, Percent_Identity=35.2517985611511, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI41327764, Length=276, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI41152114, Length=279, Percent_Identity=32.9749103942652, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI223718708, Length=159, Percent_Identity=38.3647798742138, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87081735, Length=322, Percent_Identity=37.888198757764, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1789375, Length=312, Percent_Identity=35.8974358974359, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789199, Length=345, Percent_Identity=30.4347826086957, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1788081, Length=273, Percent_Identity=32.6007326007326, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788070, Length=319, Percent_Identity=26.0188087774295, Blast_Score=91, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=343, Percent_Identity=35.5685131195335, Blast_Score=207, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6319958, Length=306, Percent_Identity=35.6209150326797, Blast_Score=199, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6319951, Length=349, Percent_Identity=32.9512893982808, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6325169, Length=331, Percent_Identity=33.8368580060423, Blast_Score=176, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6322615, Length=263, Percent_Identity=34.6007604562738, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6321052, Length=175, Percent_Identity=42.2857142857143, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24640980, Length=325, Percent_Identity=27.3846153846154, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45549126, Length=325, Percent_Identity=27.3846153846154, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24646159, Length=225, Percent_Identity=30.6666666666667, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24646155, Length=313, Percent_Identity=25.5591054313099, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39667; Mature: 39667

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSLALNHYRLLGRSGLRVSPLALGTMTFGTDWGWGAEQAEARRLFDVYVERGGNFIDT
CCCHHHHHHHHHHCCCCCEECCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEC
ANRYTEGSSERFIGEFATGRRDRLVIATKYTLPMQPDNPNSGGNHRKSMVRSVEESLRRL
CHHCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
NTDYIDLLYLHAWDATTPTEEIMRAMDDLVRAGKVLYLAVSDLPAWQAARMQTLADLRGW
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCC
SPLIGLQIEYSLLERTVERELIPMAQELGLGVIPWSPLSGGILSGKYSRQDLQVQEEENG
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEECCCCCCCCCCEECCCCC
TRRAMVRDKGMLTERNITIAETVLTLARETDFSPSQVALAWTLRNPAVTAPIIGARTLAQ
CCEEHHHCCCCEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHH
LEDNLGALEVRLTEEQWRRLDTASAIELGFPHDFLALQVTRDIMFGGLTIERR
HHCCCCEEEEEECHHHHHHCCCCCEEECCCCCCHHHHHEEHHHHCCCEEEECC
>Mature Secondary Structure
MLTSLALNHYRLLGRSGLRVSPLALGTMTFGTDWGWGAEQAEARRLFDVYVERGGNFIDT
CCCHHHHHHHHHHCCCCCEECCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEC
ANRYTEGSSERFIGEFATGRRDRLVIATKYTLPMQPDNPNSGGNHRKSMVRSVEESLRRL
CHHCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
NTDYIDLLYLHAWDATTPTEEIMRAMDDLVRAGKVLYLAVSDLPAWQAARMQTLADLRGW
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCC
SPLIGLQIEYSLLERTVERELIPMAQELGLGVIPWSPLSGGILSGKYSRQDLQVQEEENG
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEECCCCCCCCCCEECCCCC
TRRAMVRDKGMLTERNITIAETVLTLARETDFSPSQVALAWTLRNPAVTAPIIGARTLAQ
CCEEHHHCCCCEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHH
LEDNLGALEVRLTEEQWRRLDTASAIELGFPHDFLALQVTRDIMFGGLTIERR
HHCCCCEEEEEECHHHHHHCCCCCEEECCCCCCHHHHHEEHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]