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The map label for this gene is copA [H]

Identifier: 157369393

GI number: 157369393

Start: 1267769

End: 1267969

Strand: Reverse

Name: copA [H]

Synonym: Spro_1150

Alternate gene names: 157369393

Gene position: 1267969-1267769 (Counterclockwise)

Preceding gene: 157369395

Following gene: 157369392

Centisome position: 23.27

GC content: 54.73

Gene sequence:

>201_bases
ATGTCACAAATTACCGTACTGGCATTGCAGGGGCTGACCTGCATGCATTGTGTAGGTAGCACACGTAAAGCTTTAGAAGC
CGTGCCTGGCGTTAGCGCCGTGGAAGTCGCCCTTGATAGCGCCAAAGTAACCGGCGACGTCGCGCCACAAATGCTGATTA
ACGCGGTGGAACAGGCCGGTTATCAAGCCACCCTTGCCTAA

Upstream 100 bases:

>100_bases
CTCCTTGACCTTCCCCTTGCTGGAAGGTTTATCCTTCATTCTTAGTGAAAACAGGTAAAGCGGTCAACCTTTAAACACCA
TTCTTGAGAGGAATCGAACC

Downstream 100 bases:

>100_bases
CCTCCTCATAGGCCGAGCCAAGACCACGGGGCGCACATCAATGCGCCCTTTTTTCTTTGGGATAATTCCTTCACTCTTCA
GACTTTCTTGTCTGCCTGAT

Product: heavy metal transport/detoxification protein

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 66; Mature: 65

Protein sequence:

>66_residues
MSQITVLALQGLTCMHCVGSTRKALEAVPGVSAVEVALDSAKVTGDVAPQMLINAVEQAGYQATLA

Sequences:

>Translated_66_residues
MSQITVLALQGLTCMHCVGSTRKALEAVPGVSAVEVALDSAKVTGDVAPQMLINAVEQAGYQATLA
>Mature_65_residues
SQITVLALQGLTCMHCVGSTRKALEAVPGVSAVEVALDSAKVTGDVAPQMLINAVEQAGYQATLA

Specific function: Involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 HMA domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 6729; Mature: 6598

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQITVLALQGLTCMHCVGSTRKALEAVPGVSAVEVALDSAKVTGDVAPQMLINAVEQAG
CCCEEEEHHCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
YQATLA
CEECCC
>Mature Secondary Structure 
SQITVLALQGLTCMHCVGSTRKALEAVPGVSAVEVALDSAKVTGDVAPQMLINAVEQAG
CCEEEEHHCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
YQATLA
CEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]