Click here to switch to the map view.

The map label for this gene is clpX [H]

Identifier: 157369339

GI number: 157369339

Start: 1205361

End: 1206632

Strand: Direct

Name: clpX [H]

Synonym: Spro_1096

Alternate gene names: 157369339

Gene position: 1205361-1206632 (Clockwise)

Preceding gene: 157369338

Following gene: 157369340

Centisome position: 22.12

GC content: 54.25

Gene sequence:

>1272_bases
ATGACAGATAAGCGCAAAGACGGTTCAGGAAAGCTGCTGTACTGCTCTTTCTGCGGCAAAAGCCAGCATGAAGTGCGTAA
GCTGATTGCCGGTCCGTCAGTGTATATCTGCGATGAATGTGTTGACCTGTGTAACGACATTATTCGCGAAGAGATTAAAG
AAGTTTCACCGCATCGTGAGCGCAGCGCGCTGCCGACGCCGCATGAGATCCGCCACCACCTGGATGACTACGTCATCGGT
CAGGAACCGGCGAAGAAAGTGCTGGCGGTAGCGGTGTATAACCACTACAAACGCCTGCGCAACGGCGATACCAGCAACGG
TATCGAGTTGGGCAAAAGCAACATTCTGCTGATTGGTCCTACCGGTAGCGGTAAAACCTTGCTGGCGGAAACGCTGGCAC
GCTTCCTGGATGTGCCTTTCACCATGGCCGATGCCACCACGCTGACCGAAGCCGGTTATGTGGGTGAGGACGTGGAGAAT
ATTATCCAGAAGTTGCTGCAGAAATGTGACTACGACGTGCAGAAAGCCCAGCGCGGCATCGTCTATATCGATGAAATCGA
TAAGATTTCTCGTAAGTCAGACAACCCGTCCATTACCCGTGACGTTTCGGGTGAGGGCGTGCAGCAGGCGCTGTTGAAGC
TGATCGAAGGCACTATTGCTGCCGTTCCTCCTCAGGGGGGCCGCAAGCATCCGCAGCAGGAATTCCTGCAGGTTGATACC
TCGAAAATCCTGTTTATCTGTGGCGGCGCATTTGCCGGCCTGGATAAAGTGATCGGTCAGCGCGTTAATACCGGTTCCGG
TATTGGTTTTGGCGCCACCGTGAAGGGTGAGTCTGAGAAAGCGACCGAAGGCGAACTGCTGCTGCAGGCTGAACCGGAAG
ATCTGATCAAGTTTGGCCTGATCCCTGAGTTCATCGGTCGTCTGCCGGTCGTGGCCACGCTGAGTGAGCTGAGTGAAGAT
GCGCTGATCCAGATCCTGAAAGAGCCGAAAAATGCCCTGACCAAACAGTATCAGGCATTGTTCAATCTGGAAGGTGTGGA
GCTGGAATTCCGTGAAGAAGCACTGAACGCCATCGCCAGAAAGGCGATGAAACGCAAAACCGGTGCACGTGGCCTGCGTT
CTATCGTGGAAGGCGCACTGCTGGACACCATGTATGACCTGCCTTCAATGGACAGCGTCGACAAAGTGGTGATCGACGAA
TCGGTCATCGCCGGCCAGTCCAAACCGTTGCTGATTTACGGCAAACCGGAAGCACAGGCTTCAGGCGAATAA

Upstream 100 bases:

>100_bases
GCTCGCTCTGGTGAGCATTATCGGCATTCCTGGTATGAATTCGGGGCGCACGGCCGCCGTGATTTTCCTGCGGGACAAAG
ACTAAAGAAGAGGTTTACTG

Downstream 100 bases:

>100_bases
TTCGCCAGTCAAACCAGAAAGTTAATGTCAAAATGGGGGATTTTATCCCCCATTTTTATTTCCTGCGTTCTTGCCGTTGA
ATGTAAGAGATTCATCCCCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRERSALPTPHEIRHHLDDYVIG
QEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIGQRVNTGSGIGFGATVKGESEKATEGELLLQAEPEDLIKFGLIPEFIGRLPVVATLSELSED
ALIQILKEPKNALTKQYQALFNLEGVELEFREEALNAIARKAMKRKTGARGLRSIVEGALLDTMYDLPSMDSVDKVVIDE
SVIAGQSKPLLIYGKPEAQASGE

Sequences:

>Translated_423_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRERSALPTPHEIRHHLDDYVIG
QEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIGQRVNTGSGIGFGATVKGESEKATEGELLLQAEPEDLIKFGLIPEFIGRLPVVATLSELSED
ALIQILKEPKNALTKQYQALFNLEGVELEFREEALNAIARKAMKRKTGARGLRSIVEGALLDTMYDLPSMDSVDKVVIDE
SVIAGQSKPLLIYGKPEAQASGE
>Mature_422_residues
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRERSALPTPHEIRHHLDDYVIGQ
EPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENI
IQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDTS
KILFICGGAFAGLDKVIGQRVNTGSGIGFGATVKGESEKATEGELLLQAEPEDLIKFGLIPEFIGRLPVVATLSELSEDA
LIQILKEPKNALTKQYQALFNLEGVELEFREEALNAIARKAMKRKTGARGLRSIVEGALLDTMYDLPSMDSVDKVVIDES
VIAGQSKPLLIYGKPEAQASGE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=429, Percent_Identity=45.4545454545455, Blast_Score=313, Evalue=2e-85,
Organism=Escherichia coli, GI1786642, Length=424, Percent_Identity=93.3962264150943, Blast_Score=806, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=44, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=45.3376205787781, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=45.3376205787781, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=401, Percent_Identity=38.6533665835411, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=39.84375, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=427, Percent_Identity=40.2810304449649, Blast_Score=275, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24648291, Length=321, Percent_Identity=46.417445482866, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24648289, Length=321, Percent_Identity=46.417445482866, Blast_Score=286, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46231; Mature: 46099

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRE
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHH
RSALPTPHEIRHHLDDYVIGQEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGP
HCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCE
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVIGQRVNTGSGIGFGATVKGESEKATEGELLLQAEPEDLIKFGL
CEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCEEEECCHHHHHHHCC
IPEFIGRLPVVATLSELSEDALIQILKEPKNALTKQYQALFNLEGVELEFREEALNAIAR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KAMKRKTGARGLRSIVEGALLDTMYDLPSMDSVDKVVIDESVIAGQSKPLLIYGKPEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCC
SGE
CCC
>Mature Secondary Structure 
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRE
CCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHH
RSALPTPHEIRHHLDDYVIGQEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGP
HCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCE
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVIGQRVNTGSGIGFGATVKGESEKATEGELLLQAEPEDLIKFGL
CEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCEEEECCHHHHHHHCC
IPEFIGRLPVVATLSELSEDALIQILKEPKNALTKQYQALFNLEGVELEFREEALNAIAR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KAMKRKTGARGLRSIVEGALLDTMYDLPSMDSVDKVVIDESVIAGQSKPLLIYGKPEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCC
SGE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA