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The map label for this gene is leuE [H]

Identifier: 157369229

GI number: 157369229

Start: 1090673

End: 1091350

Strand: Reverse

Name: leuE [H]

Synonym: Spro_0986

Alternate gene names: 157369229

Gene position: 1091350-1090673 (Counterclockwise)

Preceding gene: 157369230

Following gene: 157369228

Centisome position: 20.03

GC content: 53.1

Gene sequence:

>678_bases
GTGTTATTGGCTGTCAGTTCCGCGCATGGAGAGGTTATTGTGTTAGAAAGTTTTGGCGTCCTGAATCTTTGGACCTATCT
GGCCGGGGTGATTTTTATCATCATCCTGCCGGGCCCGAATACGTTGTATGTGTTGAAAACCGGCGTAACACGCGGTGTGC
GGGCCGGCTATACCGCCGCGCTGGGCGTGTTTATCGGTGATGCAATCCTGATTTTCTGCGCCTATATTGGCGTGGCCTCG
CTGATCCGCACCACGCCGTTTCTGTTTACCCTGGTGCGTTTTCTCGGCGCGATTTACCTGCTGTTCCTGGGTGCCAAGAT
TCTCTACGCCACCTTTATCCAGAAAAATGCCGAGCAGCATCAACAGATTGAAGGCAGCCACAGCATTCTGCGCAAATCGC
TGACGCTCAGCCTGACCAATCCGAAAGCGATCCTGTTTTATGTGTCGTTCTTCGTACAGTTTATCGATTTCAACTATGCC
CACACCGGTCTGTCGTTCACCATTCTGGCGTTGATCCTCGAATCGGTCAGTTTTATCTACATGACCACGCTGATCTTTTC
CGGCGCGATGCTGGCGCACTTCTTTAACCACAAGAAAGGCCTGGCAAAACTGGGCAATGGTCTGATTGGCCTGCTGTTCC
TCGGCTTCGCCACCCGCCTGGCGACCCTCAGCTCCTGA

Upstream 100 bases:

>100_bases
CGCGTAACTGATGGCGAAATACGGCAATCAACATGAAGTTTATTACGTTGCCAACCCGCCCCCGCGGCGTTAGGATCGCG
CCCGGCTACGGGTGTAGCCA

Downstream 100 bases:

>100_bases
TCCCGCCGATTAACGGCTGACTCATTCAGCCGTTATGTCACGCAGAGCAAACCGATTGTCAGGCAGACAAAAGTCCTGCC
GCTGGGCCTGCTGTAGACTT

Product: leucine export protein LeuE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLLAVSSAHGEVIVLESFGVLNLWTYLAGVIFIIILPGPNTLYVLKTGVTRGVRAGYTAALGVFIGDAILIFCAYIGVAS
LIRTTPFLFTLVRFLGAIYLLFLGAKILYATFIQKNAEQHQQIEGSHSILRKSLTLSLTNPKAILFYVSFFVQFIDFNYA
HTGLSFTILALILESVSFIYMTTLIFSGAMLAHFFNHKKGLAKLGNGLIGLLFLGFATRLATLSS

Sequences:

>Translated_225_residues
MLLAVSSAHGEVIVLESFGVLNLWTYLAGVIFIIILPGPNTLYVLKTGVTRGVRAGYTAALGVFIGDAILIFCAYIGVAS
LIRTTPFLFTLVRFLGAIYLLFLGAKILYATFIQKNAEQHQQIEGSHSILRKSLTLSLTNPKAILFYVSFFVQFIDFNYA
HTGLSFTILALILESVSFIYMTTLIFSGAMLAHFFNHKKGLAKLGNGLIGLLFLGFATRLATLSS
>Mature_225_residues
MLLAVSSAHGEVIVLESFGVLNLWTYLAGVIFIIILPGPNTLYVLKTGVTRGVRAGYTAALGVFIGDAILIFCAYIGVAS
LIRTTPFLFTLVRFLGAIYLLFLGAKILYATFIQKNAEQHQQIEGSHSILRKSLTLSLTNPKAILFYVSFFVQFIDFNYA
HTGLSFTILALILESVSFIYMTTLIFSGAMLAHFFNHKKGLAKLGNGLIGLLFLGFATRLATLSS

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=209, Percent_Identity=62.200956937799, Blast_Score=259, Evalue=1e-70,
Organism=Escherichia coli, GI48994978, Length=189, Percent_Identity=29.1005291005291, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786522, Length=129, Percent_Identity=31.7829457364341, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 24586; Mature: 24586

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAVSSAHGEVIVLESFGVLNLWTYLAGVIFIIILPGPNTLYVLKTGVTRGVRAGYTAA
CEEEEECCCCCEEEEECCCHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHCHHHHHHHH
LGVFIGDAILIFCAYIGVASLIRTTPFLFTLVRFLGAIYLLFLGAKILYATFIQKNAEQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQIEGSHSILRKSLTLSLTNPKAILFYVSFFVQFIDFNYAHTGLSFTILALILESVSFIY
HHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHH
MTTLIFSGAMLAHFFNHKKGLAKLGNGLIGLLFLGFATRLATLSS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLAVSSAHGEVIVLESFGVLNLWTYLAGVIFIIILPGPNTLYVLKTGVTRGVRAGYTAA
CEEEEECCCCCEEEEECCCHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHCHHHHHHHH
LGVFIGDAILIFCAYIGVASLIRTTPFLFTLVRFLGAIYLLFLGAKILYATFIQKNAEQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQIEGSHSILRKSLTLSLTNPKAILFYVSFFVQFIDFNYAHTGLSFTILALILESVSFIY
HHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHH
MTTLIFSGAMLAHFFNHKKGLAKLGNGLIGLLFLGFATRLATLSS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA