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The map label for this gene is iucD [H]

Identifier: 157369164

GI number: 157369164

Start: 1018789

End: 1020117

Strand: Reverse

Name: iucD [H]

Synonym: Spro_0919

Alternate gene names: 157369164

Gene position: 1020117-1018789 (Counterclockwise)

Preceding gene: 157369165

Following gene: 157369163

Centisome position: 18.72

GC content: 58.47

Gene sequence:

>1329_bases
ATGAATCAGCCCCTGGATTTCATCGGCATTGGCGTAGGTCCGTTCAACCTCAGCATTGCCGCTCTCGGCAGTGAAGTTGC
CGGTTTTAACAGTAAATTTCTCGAGCGCAAACCGCACTTTTCCTGGCACCCCGGCATGATGGTGCCGGATTGTCATATGC
AGACCAGTTTCCTCAAGGATCTGGTCAGCGCGGTATCGCCGACCAATCCCTACAGTTTTATTAACTATCTGGTGAAACGA
AAGAAATTTTACCGTTTCCTGACCACCGAGCTGCGCACGGTGTCGCGCGAAGAGTTTGCCGACTACCTCGACTGGGCCGC
CAATGGCCTGAAGTCGCTCGAGTTCAGCCAGGACATTCAAAGCGTGGATTTTGACGACCAGCAGCGGCAATTTGTCGTAA
CCACCCAGCGCGCCACCTACCGGGCACGCCACGTCTGTCTGGGCATCGGCAAACGCATCAAGCTGCCGGACTGCGTTACC
GAACAAAACGATCGCTGCTTCCATGCCAGCGAGATGACGTTGCGTAACCCGGATCTGACCGGCAAGCGCGTCACCATCGT
CGGCGGCGGCCAGAGCGGTGCCGATCTGTTCCTGAACATCTTCCGCGCCGAGTGGGGCCAGCCGGCGCAGTTGAACTGGA
TCTCGCGTCGCAACAACTATAACGCCCTGGATGAAGCCGCTTTCGCCAACGAGTACTTCACCCCGGACTACGTTGACAGC
TTCTATGGCCTGAACGACAGCGCCAAACAGCGCATGCTGACCGAGCAGAAGATGACTTCTGATGGCATCACCAGCGACTC
GCTGTTAGCGATTTACCGGGCGATGTACCACCAGTTTGAAGTGCTGCGCGAAAAGCCCTGGGCGCACCTGTTACCCAGCC
GCTCGCTGGCGGCGATCCAGGCCGCAGGCAACGGCTGGCAGTTAGTGACCCACCATCATCTCGATCAGGGCAAAGAAACC
TTCGATACCGATGTGGTGATCTTCGCCACCGGCTATCAGCAGGATCGTCCGGCTTTCCTTGAGCCGCTGGCGGACCGTCT
GTTAACCACCGCCGATGACCAGTACCGCGTGGCCCCCGACTTCACCCTGGAGTGGCAAGGCCCCAGCGAAAATTGCCTGT
TTGCGGTGAACGCCGGTATGCACAGTCACGGCATCGCCGAACCCCAGCTCAGCCTGATGGCCTGGCGTTCGGCTCGTATT
CTCAACCGGGCTTTAGGACGCGACCAGTTCGATTTAACGTCCACCCCGGCGGTGATCCAATGGCGCAGCCAGCAACCGGG
CACCCCAGCCCGAGCGACACACGCCATGCTCAATTACACCGAGTTTTAA

Upstream 100 bases:

>100_bases
AACTCACCTACTCGGAGCAGGATGGCGGCAGCCGTATGCTGCCAAACTATCTGCAGGATCTGGATAACCCTCTTTACCTG
GTCACCAAGGAGTTTGCCCA

Downstream 100 bases:

>100_bases
CTACACACCAATGATGGGAAACACTGGAAGATAATGATGAAGCGCAAACACCTCTGGGTATTAAATCCTTGTCTGCTGGC
GATGATCGCACCAGCAGCAG

Product: L-lysine 6-monooxygenase (NADPH)

Products: NA

Alternate protein names: Lysine 6-N-hydroxylase; Lysine N(6)-hydroxylase; Lysine-N-oxygenase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNQPLDFIGIGVGPFNLSIAALGSEVAGFNSKFLERKPHFSWHPGMMVPDCHMQTSFLKDLVSAVSPTNPYSFINYLVKR
KKFYRFLTTELRTVSREEFADYLDWAANGLKSLEFSQDIQSVDFDDQQRQFVVTTQRATYRARHVCLGIGKRIKLPDCVT
EQNDRCFHASEMTLRNPDLTGKRVTIVGGGQSGADLFLNIFRAEWGQPAQLNWISRRNNYNALDEAAFANEYFTPDYVDS
FYGLNDSAKQRMLTEQKMTSDGITSDSLLAIYRAMYHQFEVLREKPWAHLLPSRSLAAIQAAGNGWQLVTHHHLDQGKET
FDTDVVIFATGYQQDRPAFLEPLADRLLTTADDQYRVAPDFTLEWQGPSENCLFAVNAGMHSHGIAEPQLSLMAWRSARI
LNRALGRDQFDLTSTPAVIQWRSQQPGTPARATHAMLNYTEF

Sequences:

>Translated_442_residues
MNQPLDFIGIGVGPFNLSIAALGSEVAGFNSKFLERKPHFSWHPGMMVPDCHMQTSFLKDLVSAVSPTNPYSFINYLVKR
KKFYRFLTTELRTVSREEFADYLDWAANGLKSLEFSQDIQSVDFDDQQRQFVVTTQRATYRARHVCLGIGKRIKLPDCVT
EQNDRCFHASEMTLRNPDLTGKRVTIVGGGQSGADLFLNIFRAEWGQPAQLNWISRRNNYNALDEAAFANEYFTPDYVDS
FYGLNDSAKQRMLTEQKMTSDGITSDSLLAIYRAMYHQFEVLREKPWAHLLPSRSLAAIQAAGNGWQLVTHHHLDQGKET
FDTDVVIFATGYQQDRPAFLEPLADRLLTTADDQYRVAPDFTLEWQGPSENCLFAVNAGMHSHGIAEPQLSLMAWRSARI
LNRALGRDQFDLTSTPAVIQWRSQQPGTPARATHAMLNYTEF
>Mature_442_residues
MNQPLDFIGIGVGPFNLSIAALGSEVAGFNSKFLERKPHFSWHPGMMVPDCHMQTSFLKDLVSAVSPTNPYSFINYLVKR
KKFYRFLTTELRTVSREEFADYLDWAANGLKSLEFSQDIQSVDFDDQQRQFVVTTQRATYRARHVCLGIGKRIKLPDCVT
EQNDRCFHASEMTLRNPDLTGKRVTIVGGGQSGADLFLNIFRAEWGQPAQLNWISRRNNYNALDEAAFANEYFTPDYVDS
FYGLNDSAKQRMLTEQKMTSDGITSDSLLAIYRAMYHQFEVLREKPWAHLLPSRSLAAIQAAGNGWQLVTHHHLDQGKET
FDTDVVIFATGYQQDRPAFLEPLADRLLTTADDQYRVAPDFTLEWQGPSENCLFAVNAGMHSHGIAEPQLSLMAWRSARI
LNRALGRDQFDLTSTPAVIQWRSQQPGTPARATHAMLNYTEF

Specific function: This is one of the proteins involved in the biosynthesis of siderophores (such as the dihydroxamate siderophore, aerobactin), which are chelators that mediate the high-affinity iron transport systems induced by the organism under iron-stressed conditions

COG id: COG3486

COG function: function code Q; Lysine/ornithine N-monooxygenase

Gene ontology:

Cell location: Cytoplasm. Cell membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.14.13.59 [H]

Molecular weight: Translated: 50172; Mature: 50172

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPLDFIGIGVGPFNLSIAALGSEVAGFNSKFLERKPHFSWHPGMMVPDCHMQTSFLKD
CCCCCCEEEEECCCCCEEHEECCCHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
LVSAVSPTNPYSFINYLVKRKKFYRFLTTELRTVSREEFADYLDWAANGLKSLEFSQDIQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SVDFDDQQRQFVVTTQRATYRARHVCLGIGKRIKLPDCVTEQNDRCFHASEMTLRNPDLT
CCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEECCCCCC
GKRVTIVGGGQSGADLFLNIFRAEWGQPAQLNWISRRNNYNALDEAAFANEYFTPDYVDS
CCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHH
FYGLNDSAKQRMLTEQKMTSDGITSDSLLAIYRAMYHQFEVLREKPWAHLLPSRSLAAIQ
HCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEE
AAGNGWQLVTHHHLDQGKETFDTDVVIFATGYQQDRPAFLEPLADRLLTTADDQYRVAPD
ECCCCCEEEEEHHHHCCCHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEECCC
FTLEWQGPSENCLFAVNAGMHSHGIAEPQLSLMAWRSARILNRALGRDQFDLTSTPAVIQ
EEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
WRSQQPGTPARATHAMLNYTEF
ECCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNQPLDFIGIGVGPFNLSIAALGSEVAGFNSKFLERKPHFSWHPGMMVPDCHMQTSFLKD
CCCCCCEEEEECCCCCEEHEECCCHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
LVSAVSPTNPYSFINYLVKRKKFYRFLTTELRTVSREEFADYLDWAANGLKSLEFSQDIQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SVDFDDQQRQFVVTTQRATYRARHVCLGIGKRIKLPDCVTEQNDRCFHASEMTLRNPDLT
CCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEECCCCCC
GKRVTIVGGGQSGADLFLNIFRAEWGQPAQLNWISRRNNYNALDEAAFANEYFTPDYVDS
CCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHH
FYGLNDSAKQRMLTEQKMTSDGITSDSLLAIYRAMYHQFEVLREKPWAHLLPSRSLAAIQ
HCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEE
AAGNGWQLVTHHHLDQGKETFDTDVVIFATGYQQDRPAFLEPLADRLLTTADDQYRVAPD
ECCCCCEEEEEHHHHCCCHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEECCC
FTLEWQGPSENCLFAVNAGMHSHGIAEPQLSLMAWRSARILNRALGRDQFDLTSTPAVIQ
EEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
WRSQQPGTPARATHAMLNYTEF
ECCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3275632; 10064136 [H]