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The map label for this gene is yqaB [H]

Identifier: 157369090

GI number: 157369090

Start: 942877

End: 943443

Strand: Direct

Name: yqaB [H]

Synonym: Spro_0845

Alternate gene names: 157369090

Gene position: 942877-943443 (Clockwise)

Preceding gene: 157369089

Following gene: 157369091

Centisome position: 17.3

GC content: 58.55

Gene sequence:

>567_bases
ATGTACGACCGCTATCAGGGTCTTATTTTCGACATGGACGGCACCATTCTCGATACCGAGCCGACGCACCGAAAGGCGTG
GCGTGAAGTGTTGTCCCGTTACGGTATGACGTTTGATGAGCCCGCGGTGATGGCGTTGAGCGGTTCTCCGACCTGGCATA
TTGCCCAGGCGATTATTGCCAGCCATCAGGCCGATCTCGATCCCCATCAGTTGGCTGCAGAGAAAACCCGAGCGGTAGAG
ATTATGCTGCTGGACAGCGTGCGCCCCTTGCCGCTGATTGAGGTGGTGAAGGCCTACCATGGCCGCCGTCCAATGGCGGT
GGGTACCGGCAGTGAGCATCGCATGGCGGAAACTCTGCTGCGCCATCTGGGCCTGTTCCACTGCTTTGATGCGATCGTGG
GTGCCGATGATGTGCAGCGTCATAAGCCGGAGCCGGACACCTTCCTGCGCTGTGCCGAACTGATTGGCGTACCGCCGGAG
AAATGCGTAGTGTTTGAAGACGCAGATTTCGGCATCCAGGCGGCGAAAAGCGCCAATATGGCGGTGGTAGACGTTCGTAC
GCTGTGA

Upstream 100 bases:

>100_bases
TTCCTCTTGTGCACAGCACATTCCGCTATTACGCGATCAGCGACAACCTTCCGGCTTTACGCTAAAGTAGTTTTCTTTCC
TCAACGATCATGGAGTAACG

Downstream 100 bases:

>100_bases
GTAGTACGCTGGCGGTGATGTCGTTATTCGGCGGCAGCTTTCTCAGTGCGACGTTGTTGCCGGGAAATTCAGAAATTATT
TTGGTTGCCTTGCTGACCAA

Product: fructose-1-phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MYDRYQGLIFDMDGTILDTEPTHRKAWREVLSRYGMTFDEPAVMALSGSPTWHIAQAIIASHQADLDPHQLAAEKTRAVE
IMLLDSVRPLPLIEVVKAYHGRRPMAVGTGSEHRMAETLLRHLGLFHCFDAIVGADDVQRHKPEPDTFLRCAELIGVPPE
KCVVFEDADFGIQAAKSANMAVVDVRTL

Sequences:

>Translated_188_residues
MYDRYQGLIFDMDGTILDTEPTHRKAWREVLSRYGMTFDEPAVMALSGSPTWHIAQAIIASHQADLDPHQLAAEKTRAVE
IMLLDSVRPLPLIEVVKAYHGRRPMAVGTGSEHRMAETLLRHLGLFHCFDAIVGADDVQRHKPEPDTFLRCAELIGVPPE
KCVVFEDADFGIQAAKSANMAVVDVRTL
>Mature_188_residues
MYDRYQGLIFDMDGTILDTEPTHRKAWREVLSRYGMTFDEPAVMALSGSPTWHIAQAIIASHQADLDPHQLAAEKTRAVE
IMLLDSVRPLPLIEVVKAYHGRRPMAVGTGSEHRMAETLLRHLGLFHCFDAIVGADDVQRHKPEPDTFLRCAELIGVPPE
KCVVFEDADFGIQAAKSANMAVVDVRTL

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates fructose 1-phosphate and 6-phosphogluconate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=184, Percent_Identity=35.3260869565217, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI207113149, Length=207, Percent_Identity=31.4009661835749, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI296011028, Length=156, Percent_Identity=31.4102564102564, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1789046, Length=188, Percent_Identity=72.3404255319149, Blast_Score=280, Evalue=4e-77,
Organism=Escherichia coli, GI1787576, Length=190, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=6e-17,
Organism=Escherichia coli, GI1788021, Length=179, Percent_Identity=30.1675977653631, Blast_Score=70, Evalue=7e-14,
Organism=Escherichia coli, GI87082080, Length=189, Percent_Identity=31.2169312169312, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790151, Length=183, Percent_Identity=27.3224043715847, Blast_Score=63, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129151, Length=192, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17137324, Length=185, Percent_Identity=32.972972972973, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI116008157, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550911, Length=188, Percent_Identity=30.8510638297872, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010976
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 20976; Mature: 20976

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDRYQGLIFDMDGTILDTEPTHRKAWREVLSRYGMTFDEPAVMALSGSPTWHIAQAIIA
CCCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
SHQADLDPHQLAAEKTRAVEIMLLDSVRPLPLIEVVKAYHGRRPMAVGTGSEHRMAETLL
HHCCCCCHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
RHLGLFHCFDAIVGADDVQRHKPEPDTFLRCAELIGVPPEKCVVFEDADFGIQAAKSANM
HHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCHHEEEEECCCCCCCHHCCCCE
AVVDVRTL
EEEEEECC
>Mature Secondary Structure
MYDRYQGLIFDMDGTILDTEPTHRKAWREVLSRYGMTFDEPAVMALSGSPTWHIAQAIIA
CCCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
SHQADLDPHQLAAEKTRAVEIMLLDSVRPLPLIEVVKAYHGRRPMAVGTGSEHRMAETLL
HHCCCCCHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
RHLGLFHCFDAIVGADDVQRHKPEPDTFLRCAELIGVPPEKCVVFEDADFGIQAAKSANM
HHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCHHEEEEECCCCCCCHHCCCCE
AVVDVRTL
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]