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The map label for this gene is dgt

Identifier: 157369033

GI number: 157369033

Start: 876495

End: 878012

Strand: Direct

Name: dgt

Synonym: Spro_0788

Alternate gene names: 157369033

Gene position: 876495-878012 (Clockwise)

Preceding gene: 157369028

Following gene: 157369034

Centisome position: 16.09

GC content: 54.68

Gene sequence:

>1518_bases
ATGTCCGGGATCGACTTTAAGCAGAAAATCAGCTTCCAGCGGCCATTCAGCAAGCCAATCGAAGCCGAGGAAGAATACGA
TATTGTCCGGCAGTTCGAGAGCGATCGCGGGCGCATAGTCAATTCCGCCGCTATTCGCCGTCTGCAGCAAAAAACCCAGG
TGTTTCCTCTCGAGCGTAACGCCGCGGTCCGCAGTCGCCTGACGCACTCGATGGAAGTGCAACAGGTCGGAAGGCATATC
GCCAAAGAGATCCTCAATCGTTTTAAACAGGACGGGCGAGTCGACGCTCTCGGCCTGACCAAACTGCTGGATCCTTTTGA
AAGCATTGTCGAAATGGCCTGCCTGATGCACGACATCGGTAACCCGCCTTTTGGTCATTTTGGCGAGTCGGCGATCAACA
ACTGGTTTTCCCAGCGTCTCGATCCCGCCAGCTGCGGCAGCGAACCGGCCAGCAACGATCGCTGCCAGGTCAGCGCATTG
CGTCTGCACGAAGGCGAGAGCGATCTTAACCGCCTGCGCAGCCGCATCCGTCACGACCTCAGCCATTTTGAAGGTAATGC
CCAGGCGATCCGGCTGGTGCATACCCTACTGAAGCTTAACCTGACCTACGCGCAGGTGGGCTGTATCCTGAAATATACCC
GCCCGGCCTATTGGGCGAGTGACATTCCCGCCAGCCATAATTACCTGATGAAAAAACCGGGCTTTTATCTGGCGGAAGAG
GCCTTTGTCGATCGCCTGCGGCGCGAGCTGAATATGGGCGAGTTCGACCGTTTCCCATTGACCTATATTATGGAAGCCGC
TGACGATATTTCCTACTGCGTGGCCGATCTGGAAGATGCGGTGGAAAAAAACATTTTTACCGTCGAGCAGCTTTACCAGC
ATTTAACCCAGGAGTGGGGCGAAGTCACGCCGGGTGATTTGTTTGATAAAACCGTGGCCAGCGCTTTTCGCAAGATCGCG
CACGGTGGCGCGCGGCGCAGTAGCGAAGATCAGTTCTTCATGTATTTACGGGTCTTTACCGTGGCGCGATTGGTCCCGCA
TGCGGCGCAGCGTTTTATTGATAACCTGGAGGCGGTCTATCAGGGGAACTTTAATCAGGCGTTGCTGGAGGACTCCAGCC
CGGCTTACCAATTACTGAAAATATTCAAGAATGTCGCGTTCAAACACGTGTTCAATCACCCCGAAGTGGAGCAGCTGGAG
CTGCAGGGCTATCGGGTGATCAGCGGCCTGCTGGATATCTACAGCCCACTGTTGGCGATGCCGCTGGCGGACTTTACCCT
GCTGGTGCAGGAAGACAGCCATCGAGCTTACCCGATCGAAACGCGTCTGTTTCATAAGCTTTCAACCAAGCATCGGCTGG
CCTATATCGAAGCGATTGAAGGCCTGCAACATCTGTCACCCGAGCAGTTGGCGATCCGCGAGTATTATTTCCGTGCGCGG
TTACTGCAGGATTATATCAGCGGCATGACCGATCTTTATGCCTATGACGAATACCGGCGATTAATGGCTGCGGAATAA

Upstream 100 bases:

>100_bases
TTTCGCCATAGTCTATCATGGCTCTCATAGAGAGATAATCCGTTGCATATGCCGTCGGGAATTGTTATCACGGAGGCAGG
GTGCAACGGCGGAGAAACAG

Downstream 100 bases:

>100_bases
TTCATTCAGCTAATAAATATTATTTTAAGCACTTTGCCTGGTGCTACGGTCCTATTTGGAGTTTTGTAAAGACGGACAAT
ATTTGTTTACTATTACCAAT

Product: deoxyguanosinetriphosphate triphosphohydrolase

Products: NA

Alternate protein names: dGTP triphosphohydrolase; dGTPase

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSGIDFKQKISFQRPFSKPIEAEEEYDIVRQFESDRGRIVNSAAIRRLQQKTQVFPLERNAAVRSRLTHSMEVQQVGRHI
AKEILNRFKQDGRVDALGLTKLLDPFESIVEMACLMHDIGNPPFGHFGESAINNWFSQRLDPASCGSEPASNDRCQVSAL
RLHEGESDLNRLRSRIRHDLSHFEGNAQAIRLVHTLLKLNLTYAQVGCILKYTRPAYWASDIPASHNYLMKKPGFYLAEE
AFVDRLRRELNMGEFDRFPLTYIMEAADDISYCVADLEDAVEKNIFTVEQLYQHLTQEWGEVTPGDLFDKTVASAFRKIA
HGGARRSSEDQFFMYLRVFTVARLVPHAAQRFIDNLEAVYQGNFNQALLEDSSPAYQLLKIFKNVAFKHVFNHPEVEQLE
LQGYRVISGLLDIYSPLLAMPLADFTLLVQEDSHRAYPIETRLFHKLSTKHRLAYIEAIEGLQHLSPEQLAIREYYFRAR
LLQDYISGMTDLYAYDEYRRLMAAE

Sequences:

>Translated_505_residues
MSGIDFKQKISFQRPFSKPIEAEEEYDIVRQFESDRGRIVNSAAIRRLQQKTQVFPLERNAAVRSRLTHSMEVQQVGRHI
AKEILNRFKQDGRVDALGLTKLLDPFESIVEMACLMHDIGNPPFGHFGESAINNWFSQRLDPASCGSEPASNDRCQVSAL
RLHEGESDLNRLRSRIRHDLSHFEGNAQAIRLVHTLLKLNLTYAQVGCILKYTRPAYWASDIPASHNYLMKKPGFYLAEE
AFVDRLRRELNMGEFDRFPLTYIMEAADDISYCVADLEDAVEKNIFTVEQLYQHLTQEWGEVTPGDLFDKTVASAFRKIA
HGGARRSSEDQFFMYLRVFTVARLVPHAAQRFIDNLEAVYQGNFNQALLEDSSPAYQLLKIFKNVAFKHVFNHPEVEQLE
LQGYRVISGLLDIYSPLLAMPLADFTLLVQEDSHRAYPIETRLFHKLSTKHRLAYIEAIEGLQHLSPEQLAIREYYFRAR
LLQDYISGMTDLYAYDEYRRLMAAE
>Mature_504_residues
SGIDFKQKISFQRPFSKPIEAEEEYDIVRQFESDRGRIVNSAAIRRLQQKTQVFPLERNAAVRSRLTHSMEVQQVGRHIA
KEILNRFKQDGRVDALGLTKLLDPFESIVEMACLMHDIGNPPFGHFGESAINNWFSQRLDPASCGSEPASNDRCQVSALR
LHEGESDLNRLRSRIRHDLSHFEGNAQAIRLVHTLLKLNLTYAQVGCILKYTRPAYWASDIPASHNYLMKKPGFYLAEEA
FVDRLRRELNMGEFDRFPLTYIMEAADDISYCVADLEDAVEKNIFTVEQLYQHLTQEWGEVTPGDLFDKTVASAFRKIAH
GGARRSSEDQFFMYLRVFTVARLVPHAAQRFIDNLEAVYQGNFNQALLEDSSPAYQLLKIFKNVAFKHVFNHPEVEQLEL
QGYRVISGLLDIYSPLLAMPLADFTLLVQEDSHRAYPIETRLFHKLSTKHRLAYIEAIEGLQHLSPEQLAIREYYFRARL
LQDYISGMTDLYAYDEYRRLMAAE

Specific function: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs

COG id: COG0232

COG function: function code F; dGTP triphosphohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dGTPase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1786355, Length=505, Percent_Identity=66.9306930693069, Blast_Score=712, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DGTP_SERP5 (A8G9V4)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477022.1
- ProteinModelPortal:   A8G9V4
- SMR:   A8G9V4
- STRING:   A8G9V4
- GeneID:   5604064
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0788
- eggNOG:   COG0232
- HOGENOM:   HBG470926
- OMA:   LVEMACL
- ProtClustDB:   PRK04926
- BioCyc:   SPRO399741:SPRO_0788-MONOMER
- HAMAP:   MF_00030
- InterPro:   IPR006261
- InterPro:   IPR020779
- InterPro:   IPR003607
- SMART:   SM00471
- TIGRFAMs:   TIGR01353

Pfam domain/function: NA

EC number: =3.1.5.1

Molecular weight: Translated: 58285; Mature: 58154

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGIDFKQKISFQRPFSKPIEAEEEYDIVRQFESDRGRIVNSAAIRRLQQKTQVFPLERN
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCH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HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA