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The map label for this gene is nhaR [H]

Identifier: 157368940

GI number: 157368940

Start: 767251

End: 768144

Strand: Direct

Name: nhaR [H]

Synonym: Spro_0695

Alternate gene names: 157368940

Gene position: 767251-768144 (Clockwise)

Preceding gene: 157368939

Following gene: 157368942

Centisome position: 14.08

GC content: 54.03

Gene sequence:

>894_bases
ATGTCGCATATCAACTTTAATCACCTTTACTACTTCTGGCAGGTCTGCAAGGAAGGTTCGGTGGTCGGCGCCGCCGAAGC
CTTGTTTCTGACACCGCAGACCATCACCGGCCAGATCAAAGCGTTGGAGGAGCGTTTGGACGGCAAGCTGTTCAAGCGTC
AGGGGCGTGGGCTGGTGCCATCCGAATTGGGGCAACTGGTTTTTCGCTATGCCGACAAGATGTTTATGCTCAGCCAGGAA
ATGCTGGATATCGTTAATTACCGCAAGGAATCCAACCTGCTGTTTGACGTCGGGGTAGCGGATGCGTTGTCCAAACGTTT
GGTGAGCCAGGTGCTGGAGACGGCGGTAGTGGTGGATAATGAGCAAATTCACCTGCGGTGCTTTGAGTCGACGCATGAGA
TGCTGCTGGAGCAGCTCAGTCAGCATAAGCTCGATATGATCCTGTCAGACTGCCCGGTGGATTCCAGCCAGCAGGAAGGG
TTGTTTTCGCTCAAGCTGGGTGAATGCGGTATCAGTTTCTTCTGCCGCCAACCGGCACCGGATCTGCCGTTCCCCGCCTG
TCTGGAACAGCGAAAACTGCTGATCCCGGGTCGGCGTTCAATGTTGGGCCGTAAACTGCTGAACTGGTTTAACACCCAGG
GCATTCAGGTGGAGATCCTGGGCGAGTTTGATGATGCGGCCCTGATGAAAACTTTTGGCATGTACCACAACGCGATCTTC
GTTGCGCCGACGCTGTATGCGCAGGATACCTATAACGATGATGACGTGGTGGAGATTGGACGTATTGATAGCGTGCAGGA
AGAGTACTACATCATCTTTGCCGAGCGCATGATCCAGCATCCGGCGGTACAGCGGGTGTGCAACAAGGACTTCTCTGCGT
TGTTTGCTTACTAG

Upstream 100 bases:

>100_bases
AATGCAGCAACAGGTTGTCTGAAACAGGGAAAGGACATTAGTCGCTCGTTACGGCCGCAGTTTTGCCATGACGGAATGTT
AAGGAGAGCACCTCGTGAGG

Downstream 100 bases:

>100_bases
ACCGGGTAATGCAGACGTAAAAAAACCGGCCTGAGCCGGTTTTTTTTCAAGCAGACAACACGATGCTTATTACAAAGCGT
TGATGCGCGCCGACAGGTTT

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEERLDGKLFKRQGRGLVPSELGQLVFRYADKMFMLSQE
MLDIVNYRKESNLLFDVGVADALSKRLVSQVLETAVVVDNEQIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQEG
LFSLKLGECGISFFCRQPAPDLPFPACLEQRKLLIPGRRSMLGRKLLNWFNTQGIQVEILGEFDDAALMKTFGMYHNAIF
VAPTLYAQDTYNDDDVVEIGRIDSVQEEYYIIFAERMIQHPAVQRVCNKDFSALFAY

Sequences:

>Translated_297_residues
MSHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEERLDGKLFKRQGRGLVPSELGQLVFRYADKMFMLSQE
MLDIVNYRKESNLLFDVGVADALSKRLVSQVLETAVVVDNEQIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQEG
LFSLKLGECGISFFCRQPAPDLPFPACLEQRKLLIPGRRSMLGRKLLNWFNTQGIQVEILGEFDDAALMKTFGMYHNAIF
VAPTLYAQDTYNDDDVVEIGRIDSVQEEYYIIFAERMIQHPAVQRVCNKDFSALFAY
>Mature_296_residues
SHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEERLDGKLFKRQGRGLVPSELGQLVFRYADKMFMLSQEM
LDIVNYRKESNLLFDVGVADALSKRLVSQVLETAVVVDNEQIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQEGL
FSLKLGECGISFFCRQPAPDLPFPACLEQRKLLIPGRRSMLGRKLLNWFNTQGIQVEILGEFDDAALMKTFGMYHNAIFV
APTLYAQDTYNDDDVVEIGRIDSVQEEYYIIFAERMIQHPAVQRVCNKDFSALFAY

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=296, Percent_Identity=81.7567567567568, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1788297, Length=234, Percent_Identity=25.2136752136752, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33957; Mature: 33825

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEERLDGKLFKRQGRGLVP
CCCCCHHHHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHHHHCHHHHHHCCCCCCH
SELGQLVFRYADKMFMLSQEMLDIVNYRKESNLLFDVGVADALSKRLVSQVLETAVVVDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHEECC
EQIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQEGLFSLKLGECGISFFCRQPAP
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHEEECCCCC
DLPFPACLEQRKLLIPGRRSMLGRKLLNWFNTQGIQVEILGEFDDAALMKTFGMYHNAIF
CCCCHHHHHCCCEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCEEE
VAPTLYAQDTYNDDDVVEIGRIDSVQEEYYIIFAERMIQHPAVQRVCNKDFSALFAY
EEEEEEECCCCCCCCEEEECCCCCCCHHHEEHHHHHHHHCHHHHHHHCCCHHHHHCC
>Mature Secondary Structure 
SHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEERLDGKLFKRQGRGLVP
CCCCHHHHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHHHHCHHHHHHCCCCCCH
SELGQLVFRYADKMFMLSQEMLDIVNYRKESNLLFDVGVADALSKRLVSQVLETAVVVDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHEECC
EQIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQEGLFSLKLGECGISFFCRQPAP
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHEEECCCCC
DLPFPACLEQRKLLIPGRRSMLGRKLLNWFNTQGIQVEILGEFDDAALMKTFGMYHNAIF
CCCCHHHHHCCCEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCEEE
VAPTLYAQDTYNDDDVVEIGRIDSVQEEYYIIFAERMIQHPAVQRVCNKDFSALFAY
EEEEEEECCCCCCCCEEEECCCCCCCHHHEEHHHHHHHHCHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]