BacMap

Definition	Serratia proteamaculans 568 chromosome, complete genome.
Accession	NC_009832
Length	5,448,853

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The map label for this gene is hbdH1 [H]

Identifier: 157368840

GI number: 157368840

Start: 659812

End: 660582

Strand: Direct

Name: hbdH1 [H]

Synonym: Spro_0595

Alternate gene names: 157368840

Gene position: 659812-660582 (Clockwise)

Preceding gene: 157368839

Following gene: 157368842

Centisome position: 12.11

GC content: 61.61

Gene sequence:

>771_bases
ATGAATTTACAAGGCAAAACGGCACTGGTGACCGGTTCGACCAGCGGTATCGGCCTCGGGCTGGCCGCCAGCCTGGCGGC
CGCGGGCGCCCAGGTGATCCTCAACGGTTTTGGCGAGGTGGAGCAGGCGAAGGCACATATCGCAGGTTTGGGCGTCGCGC
CCGGCTACCACGACGCAGATCTCAGCGATCCGCAACAGATCGCCGATCTGATGCGTTATGTCGAGCTGGAGTTTGGTGGC
ACCGACATTCTGGTTAATAACGCCGGGATTCAGCATGTTTCACCCCTGGAGTCATTCCCGGCCGACAAATGGAACGCGAT
TATCGCGATTAATCTGTCGTCGGTGTTCCACACCAGCCGCCTGGCACTGCCGGGTATGCGAGAGCGCGGTTGGGGACGGA
TTATCAACGTTGCCTCGGTGCATGGGTTGGTGGCATCCAAAGACAAGGCGGCCTATGTGGCGGCCAAACACGGCGTGGTG
GGGCTGACCAAAACCATCGCGCTGGAAACCGCGCGTAGCGCCATTACCTGCAACGCCATCTGTCCCGGTTGGGTGCTGAC
GCCGTTGGTGCAGCAGCAAATTGACCAACGGATTGCCGCCGGCACCGATCCACAGCAGGCGCGCAATGACCTGCTGGCGG
AGAAACAGCCCTCGCTGGAGTTTGTGACGCCGGAGCAGTTGGGGGAACTGGCGCTGTTTCTGTGCAGCGACGCCGCAGTG
CAGGTGCGCGGTGCCGCCTGGAATATGGATGGCGGCTGGTTGGCGCAGTAA

Upstream 100 bases:

>100_bases
CTATGGTGGCATCTTCGCCATCACCCTGATTAAGAGCGCCGCAGTGCTGTTTGTGATTGGCGTGTTCTACCTGACCGGCA
TTGTTTAAAGGAGCAACAAC

Downstream 100 bases:

>100_bases
CTTTGTGGCCGGTTTCGGTACTACATGACGATCCCGGCCCCTTGCGCCCGGTCCGCCGCGTTTTTCTCTGCCAGATAGCG
CGCCGGCGGTTTACCCACCG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNLQGKTALVTGSTSGIGLGLAASLAAAGAQVILNGFGEVEQAKAHIAGLGVAPGYHDADLSDPQQIADLMRYVELEFGG
TDILVNNAGIQHVSPLESFPADKWNAIIAINLSSVFHTSRLALPGMRERGWGRIINVASVHGLVASKDKAAYVAAKHGVV
GLTKTIALETARSAITCNAICPGWVLTPLVQQQIDQRIAAGTDPQQARNDLLAEKQPSLEFVTPEQLGELALFLCSDAAV
QVRGAAWNMDGGWLAQ

Sequences:

>Translated_256_residues
MNLQGKTALVTGSTSGIGLGLAASLAAAGAQVILNGFGEVEQAKAHIAGLGVAPGYHDADLSDPQQIADLMRYVELEFGG
TDILVNNAGIQHVSPLESFPADKWNAIIAINLSSVFHTSRLALPGMRERGWGRIINVASVHGLVASKDKAAYVAAKHGVV
GLTKTIALETARSAITCNAICPGWVLTPLVQQQIDQRIAAGTDPQQARNDLLAEKQPSLEFVTPEQLGELALFLCSDAAV
QVRGAAWNMDGGWLAQ
>Mature_256_residues
MNLQGKTALVTGSTSGIGLGLAASLAAAGAQVILNGFGEVEQAKAHIAGLGVAPGYHDADLSDPQQIADLMRYVELEFGG
TDILVNNAGIQHVSPLESFPADKWNAIIAINLSSVFHTSRLALPGMRERGWGRIINVASVHGLVASKDKAAYVAAKHGVV
GLTKTIALETARSAITCNAICPGWVLTPLVQQQIDQRIAAGTDPQQARNDLLAEKQPSLEFVTPEQLGELALFLCSDAAV
QVRGAAWNMDGGWLAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=32.2834645669291, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=36.318407960199, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI15277342, Length=273, Percent_Identity=29.6703296703297, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI4504505, Length=264, Percent_Identity=26.8939393939394, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=28.1368821292776, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=36, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI142976729, Length=217, Percent_Identity=29.0322580645161, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=29.9610894941634, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI109715829, Length=247, Percent_Identity=27.5303643724696, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI59889578, Length=183, Percent_Identity=31.1475409836066, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=30.6122448979592, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=251, Percent_Identity=26.6932270916335, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7657478, Length=209, Percent_Identity=28.7081339712919, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=28.494623655914, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=29.6482412060301, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4758504, Length=205, Percent_Identity=30.2439024390244, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=29.1005291005291, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031737, Length=191, Percent_Identity=31.9371727748691, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=31.9371727748691, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=27.0588235294118, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40254986, Length=236, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI223718074, Length=172, Percent_Identity=31.3953488372093, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI40807363, Length=197, Percent_Identity=27.4111675126904, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=36.8627450980392, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=36.3636363636364, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=32.8185328185328, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=32.6848249027237, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=30.7392996108949, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=32.2834645669291, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=27.5193798449612, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=29.8039215686275, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=26.171875, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=28.3464566929134, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=27.3809523809524, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=28.6516853932584, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=25.6809338521401, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=30.5882352941176, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=28.7937743190661, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=264, Percent_Identity=28.030303030303, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=32.4607329842932, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=32.2916666666667, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=30.7291666666667, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=30.5699481865285, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=265, Percent_Identity=27.5471698113208, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=27.6264591439689, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=210, Percent_Identity=30.4761904761905, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=199, Percent_Identity=32.6633165829146, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=26.5625, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=27.5193798449612, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=25.7692307692308, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=194, Percent_Identity=29.8969072164948, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=27.7566539923954, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=28.0155642023346, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=198, Percent_Identity=24.7474747474747, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=26.0377358490566, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=32.1428571428571, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=193, Percent_Identity=31.0880829015544, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=196, Percent_Identity=30.1020408163265, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=256, Percent_Identity=28.515625, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=201, Percent_Identity=31.3432835820896, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=26.2172284644195, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=217, Percent_Identity=29.4930875576037, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=25.5725190839695, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=30.4123711340206, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320089, Length=197, Percent_Identity=27.4111675126904, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=29.8449612403101, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=32.4607329842932, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21358495, Length=229, Percent_Identity=30.1310043668122, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=27.6923076923077, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=30, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=28.0155642023346, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=29.0697674418605, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=28.2352941176471, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355631, Length=173, Percent_Identity=31.7919075144509, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28571387, Length=199, Percent_Identity=32.1608040201005, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281364892, Length=237, Percent_Identity=29.1139240506329, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=29.3650793650794, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=31.9587628865979, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221331218, Length=215, Percent_Identity=28.3720930232558, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665243, Length=215, Percent_Identity=28.3720930232558, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356301, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331216, Length=216, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665247, Length=216, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649181, Length=207, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737361, Length=243, Percent_Identity=28.3950617283951, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640492, Length=246, Percent_Identity=26.0162601626016, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 26853; Mature: 26853

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQGKTALVTGSTSGIGLGLAASLAAAGAQVILNGFGEVEQAKAHIAGLGVAPGYHDAD
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
LSDPQQIADLMRYVELEFGGTDILVNNAGIQHVSPLESFPADKWNAIIAINLSSVFHTSR
CCCHHHHHHHHHHHEEEECCCEEEEECCCCCCCCCHHHCCCCCCCEEEEEEEHHHHHHHH
LALPGMRERGWGRIINVASVHGLVASKDKAAYVAAKHGVVGLTKTIALETARSAITCNAI
HCCCCCCCCCCCCEEEHHHHHHEHCCCCCEEEEEECCCCEEHHHHHHHHHHCCEEEECCC
CPGWVLTPLVQQQIDQRIAAGTDPQQARNDLLAEKQPSLEFVTPEQLGELALFLCSDAAV
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHCCCEE
QVRGAAWNMDGGWLAQ
EEECEEECCCCCEECC
>Mature Secondary Structure
MNLQGKTALVTGSTSGIGLGLAASLAAAGAQVILNGFGEVEQAKAHIAGLGVAPGYHDAD
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
LSDPQQIADLMRYVELEFGGTDILVNNAGIQHVSPLESFPADKWNAIIAINLSSVFHTSR
CCCHHHHHHHHHHHEEEECCCEEEEECCCCCCCCCHHHCCCCCCCEEEEEEEHHHHHHHH
LALPGMRERGWGRIINVASVHGLVASKDKAAYVAAKHGVVGLTKTIALETARSAITCNAI
HCCCCCCCCCCCCEEEHHHHHHEHCCCCCEEEEEECCCCEEHHHHHHHHHHCCEEEECCC
CPGWVLTPLVQQQIDQRIAAGTDPQQARNDLLAEKQPSLEFVTPEQLGELALFLCSDAAV
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHCCCEE
QVRGAAWNMDGGWLAQ
EEECEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA