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The map label for this gene is nlpI [H]

Identifier: 157368741

GI number: 157368741

Start: 546481

End: 547365

Strand: Direct

Name: nlpI [H]

Synonym: Spro_0494

Alternate gene names: 157368741

Gene position: 546481-547365 (Clockwise)

Preceding gene: 157368740

Following gene: 157368742

Centisome position: 10.03

GC content: 50.96

Gene sequence:

>885_bases
ATGAAGCCTTTCTTGCGCTGGTGTTACGTTGCGACAGCACTCATGCTGGCAGGATGCAGCAACCATGATTGGCGTAAAGA
CGAAGTTTTGGCGATCCCGTTGCAGCCAACTCTGCAGCAGGAAGTGATCCTGGCGCGCATGGAACAAATACTTGCCAGCC
GGGCACTGACGGACGATGAGCGTGCGCAGCTTTTATATGAGCGCGGTGTACTGTATGATAGCCTCGGGCTACGTGCACTG
GCGCGCAATGATTTCTCGCAAGCGCTGGCGATACGTCCTGATATGCCAGAAGTTTTCAACTACCTGGGCATTTACTTAAC
GCAGGCAGGCAATTTTGATGCTGCCTATGAAGCGTTTGATTCTGTACTAGAGCTTGATCCAACTTACAATTACGCGCGTT
TAAACCGGGGCATCGCTCTTTATTATGGCGGCCGCTTCCCGTTGGCGCAGGATGATCTGCAGGCGTTTTATCAAGACGAC
CCAAACGATCCCTTCCGTTCGTTGTGGCTGTATCTTGTGGAAAGAGAAATCGATCCCAAGAAGGCTGACGTAGCGCTCCA
GCAGCGTTATGACAAGGCGAACCGAGGGCAATGGGGATGGAATATTGTCGAATTCTACCTGGGCAACATCAGTGAAAAAA
CGCTGATGGAAAGGCTCAAGGCAGATGCAACGGATAACACTTCGCTCGCTGAGCATCTCAGTGAAACTGACTTCTATTTA
GGTAAGCATTACCTAAGTCTGGGGGACAAGGACACCGCTTCGGCGCTGTTCAAACTGACGGTTGCTAACAACGTTCATAA
TTTCGTTGAGCACCGCTATGCATTGTTGGAATTGGCGCTGTTGGGCCAAGAACAAGACGACCTATCGGAATCGGACCAGC
AATAG

Upstream 100 bases:

>100_bases
CATGGGGTTGGGAGCTGTTCATATAACGCGGGCAGGATGCCTGCGTATTTGCAAACGGATGAAAGGATGTTCATCCAATG
TTTGTCTTCGGGAGTGGGAA

Downstream 100 bases:

>100_bases
CTGACGAACAACTATCAGCCTGATATACATTGGTTTTTTGCCAAAGTTATCGTCTTAACGGGCGAGGGCTTTTTTGTTCG
TTTTATAATCTAATTTGAGC

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDD
PNDPFRSLWLYLVEREIDPKKADVALQQRYDKANRGQWGWNIVEFYLGNISEKTLMERLKADATDNTSLAEHLSETDFYL
GKHYLSLGDKDTASALFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ

Sequences:

>Translated_294_residues
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDD
PNDPFRSLWLYLVEREIDPKKADVALQQRYDKANRGQWGWNIVEFYLGNISEKTLMERLKADATDNTSLAEHLSETDFYL
GKHYLSLGDKDTASALFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ
>Mature_294_residues
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDD
PNDPFRSLWLYLVEREIDPKKADVALQQRYDKANRGQWGWNIVEFYLGNISEKTLMERLKADATDNTSLAEHLSETDFYL
GKHYLSLGDKDTASALFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=294, Percent_Identity=87.4149659863945, Blast_Score=531, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 33756; Mature: 33756

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDE
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHH
RAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFD
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
SVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDDPNDPFRSLWLYLVEREIDPK
HHHHCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCH
KADVALQQRYDKANRGQWGWNIVEFYLGNISEKTLMERLKADATDNTSLAEHLSETDFYL
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GKHYLSLGDKDTASALFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
>Mature Secondary Structure
MKPFLRWCYVATALMLAGCSNHDWRKDEVLAIPLQPTLQQEVILARMEQILASRALTDDE
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHH
RAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFD
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
SVLELDPTYNYARLNRGIALYYGGRFPLAQDDLQAFYQDDPNDPFRSLWLYLVEREIDPK
HHHHCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCH
KADVALQQRYDKANRGQWGWNIVEFYLGNISEKTLMERLKADATDNTSLAEHLSETDFYL
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GKHYLSLGDKDTASALFKLTVANNVHNFVEHRYALLELALLGQEQDDLSESDQQ
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]