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The map label for this gene is fbp [H]

Identifier: 157368711

GI number: 157368711

Start: 516128

End: 517132

Strand: Reverse

Name: fbp [H]

Synonym: Spro_0464

Alternate gene names: 157368711

Gene position: 517132-516128 (Counterclockwise)

Preceding gene: 157368713

Following gene: 157368709

Centisome position: 9.49

GC content: 53.13

Gene sequence:

>1005_bases
ATGAAAACGTTAGGCGAATTTATCGTCGAGAAACAGCACGACTTCTCTCACGCCACCGGCGAGCTGACAGCGTTACTTTC
TGCAATTAAACTGGGCGCCAAAATCATCCACCGCGATATCAACAAAGCGGGTCTGGTTGATATTCTCGGCACCAGCGGCG
TTTCCAATGTACAGGGTGAAGTTCAGATGAAACTGGACCTGTACGCTAACGAAAAGCTGAAAGCAGCATTGAAAGCACGC
GGTGAAGTTGCGGGTATCGCTTCTGAAGAAGAAGATGAAATCGTGATATTCGACGGCGAGCGGGCTGAAAATGCCAAGTA
CGTGGTGCTGATGGATCCGTTGGACGGTTCGTCCAACATCGATGTCAACGTCTCGGTCGGTACGATTTTCTCTATCTATC
GTCGCATTACCCCGGTCGGCATTCCCGTGACCGAAGAAGACTTCCTGCAGCCAGGCAGCGCTCAGGTCGCCGCCGGCTAT
GTGGTTTATGGTTCATCCACCATGCTGGTGTACACCACCGGTTATGGCGTGCATGCCTTTACCTACGATCCTTCTCTGGG
CGTGTTCTGCCTCTCCCATGAGAAAGTTCGCTTCCCGGCTACCGGCAATATGTATTCCATCAACGAAGGTAACTACATCA
AGTTCCCGCGCGGTGTGAAGAAATACATCAAATATTGTCAGGAACAGGATGAAGCCACTCAGCGCCCTTATACCTCACGC
TACATCGGTTCGCTGGTTGCCGACTTCCACCGCAACCTGCTGAAAGGCGGCATCTATATTTATCCAAGCACCGCCAGCCA
CCCGCAAGGCAAGCTGCGCCTGCTGTATGAATGCAACCCGATGGCGTTCCTGGCGGAACAGGCCGGCGGTAAAGCCAGCG
ACGGTAAAAACCGTATTCTGGACATTACCCCGGTGAAACTGCACCAGCGTGCACCGTTCTTCGTCGGTACCAAATCCATG
GTGGAAGACGCCGAGCGCTTTATCGCCGAGAACCCGGACGAATAA

Upstream 100 bases:

>100_bases
TTGCCTATGAATAGCGTTCATCTTTGGGCTACACTGCTCGCGAATACGTTGGCGGTTTGTTAACAAACCGCTACCCATCC
GTAGATTCAGGGATTGTGTC

Downstream 100 bases:

>100_bases
CCGGTTCTATGTGGGGGGCGCCTGTCGCCCCCCTGCATTATAGTTTGAACGCCGCCATACTCTGGGCCAACAACTGGGCC
TGATCCTCCAGCGAGCGCGT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKTLGEFIVEKQHDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGVSNVQGEVQMKLDLYANEKLKAALKAR
GEVAGIASEEEDEIVIFDGERAENAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPVGIPVTEEDFLQPGSAQVAAGY
VVYGSSTMLVYTTGYGVHAFTYDPSLGVFCLSHEKVRFPATGNMYSINEGNYIKFPRGVKKYIKYCQEQDEATQRPYTSR
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKASDGKNRILDITPVKLHQRAPFFVGTKSM
VEDAERFIAENPDE

Sequences:

>Translated_334_residues
MKTLGEFIVEKQHDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGVSNVQGEVQMKLDLYANEKLKAALKAR
GEVAGIASEEEDEIVIFDGERAENAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPVGIPVTEEDFLQPGSAQVAAGY
VVYGSSTMLVYTTGYGVHAFTYDPSLGVFCLSHEKVRFPATGNMYSINEGNYIKFPRGVKKYIKYCQEQDEATQRPYTSR
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKASDGKNRILDITPVKLHQRAPFFVGTKSM
VEDAERFIAENPDE
>Mature_334_residues
MKTLGEFIVEKQHDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGVSNVQGEVQMKLDLYANEKLKAALKAR
GEVAGIASEEEDEIVIFDGERAENAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPVGIPVTEEDFLQPGSAQVAAGY
VVYGSSTMLVYTTGYGVHAFTYDPSLGVFCLSHEKVRFPATGNMYSINEGNYIKFPRGVKKYIKYCQEQDEATQRPYTSR
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKASDGKNRILDITPVKLHQRAPFFVGTKSM
VEDAERFIAENPDE

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=317, Percent_Identity=44.4794952681388, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI16579888, Length=317, Percent_Identity=44.4794952681388, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI22907028, Length=331, Percent_Identity=41.6918429003021, Blast_Score=244, Evalue=1e-64,
Organism=Escherichia coli, GI1790679, Length=333, Percent_Identity=85.8858858858859, Blast_Score=587, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI17508131, Length=328, Percent_Identity=47.2560975609756, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6323409, Length=322, Percent_Identity=42.8571428571429, Blast_Score=264, Evalue=2e-71,
Organism=Drosophila melanogaster, GI45550998, Length=326, Percent_Identity=48.159509202454, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI19921562, Length=326, Percent_Identity=48.159509202454, Blast_Score=287, Evalue=6e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 36735; Mature: 36735

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLGEFIVEKQHDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGVSNVQGE
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCE
VQMKLDLYANEKLKAALKARGEVAGIASEEEDEIVIFDGERAENAKYVVLMDPLDGSSNI
EEEEEEEECCHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCE
DVNVSVGTIFSIYRRITPVGIPVTEEDFLQPGSAQVAAGYVVYGSSTMLVYTTGYGVHAF
EEEEEHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEECCCEEEEEEECCCEEEE
TYDPSLGVFCLSHEKVRFPATGNMYSINEGNYIKFPRGVKKYIKYCQEQDEATQRPYTSR
EECCCCCEEEECCCEEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCCHHHH
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKASDGKNRIL
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCEE
DITPVKLHQRAPFFVGTKSMVEDAERFIAENPDE
EECCCEECCCCCEEECCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTLGEFIVEKQHDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGVSNVQGE
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCE
VQMKLDLYANEKLKAALKARGEVAGIASEEEDEIVIFDGERAENAKYVVLMDPLDGSSNI
EEEEEEEECCHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCE
DVNVSVGTIFSIYRRITPVGIPVTEEDFLQPGSAQVAAGYVVYGSSTMLVYTTGYGVHAF
EEEEEHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEECCCEEEEEEECCCEEEE
TYDPSLGVFCLSHEKVRFPATGNMYSINEGNYIKFPRGVKKYIKYCQEQDEATQRPYTSR
EECCCCCEEEECCCEEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCCHHHH
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKASDGKNRIL
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCEE
DITPVKLHQRAPFFVGTKSMVEDAERFIAENPDE
EECCCEECCCCCEEECCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA