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The map label for this gene is actP [H]

Identifier: 157368544

GI number: 157368544

Start: 347914

End: 349566

Strand: Reverse

Name: actP [H]

Synonym: Spro_0295

Alternate gene names: 157368544

Gene position: 349566-347914 (Counterclockwise)

Preceding gene: 157368545

Following gene: 157368542

Centisome position: 6.42

GC content: 54.08

Gene sequence:

>1653_bases
ATGAAGCCTTTATTGTCTGTCGCCGCCCTACTGATGCTGCCGGGCCTGGCTTTTGCTGATGCCATTAGTGGCGAAGTTCA
TCGCCAGCCGCTGAATATTCAGGCGATCGTGATGTTCGTACTGTTTGTCGGTGCCACGCTATACATCACTTACTGGGCTT
CCAAACGAACTCGTTCACGCCAGGATTACTACACCGCAGGCGGCAAAATCACCGGCCTGCAGAACGGCCTGGCGATTGCC
GGCGACTTTATGTCAGCCGCTTCTTTCCTGGGTATTTCCGCACTGGTGTATACCTCTGGCTATGACGGACTGATTTATTC
CATCGGCTTCCTGATCGGCTGGCCGATCATTTTGTTCCTGATTGCAGAACGCCTGCGAAATCTGGGCCGTTATACCTTTG
CTGACGTGGCCTCTTACCGACTTAAGCAGAAACCAATCCGTACCCTTTCGGCCTGCGGCTCACTGGTGGTGGTCGCGCTA
TACCTGATTGCACAGATGGTTGGCGCCGGTAAGCTGATCCAGTTACTGTTTGGTCTTAACTACCACGTGGCGGTGATCCT
GGTCGGTATTTTAATGGTGCTGTACGTGCTGTTCGGCGGCATGCTGGCAACCACCTGGGTACAGATTATCAAAGCGGTAT
TGTTGCTGGCCGGTGCCAGTTTTATGGCGCTGATGGTGATGAAATCGGTCAATTTTGACTTCAATACCCTGTTTGCCGAG
GCCGTGAAGGTGCATCCAAAAGGCATCGCCATCATGAGCCCGGGCGGACTGGTGTCCGATCCTATTTCCGCGCTCTCGTT
GGGGCTGGCGCTGATGTTTGGTACTGCGGGTCTGCCGCATATTTTGATGCGCTTCTTTACCGTCAGCGATGCCAAAGAAG
CCCGCAAGAGTGTGTTCTATGCCACCGGCTTTATCGGTTACTTCTATATCCTGACCTTTATTATCGGCTTCGGCGCAATT
TTGTTAGTCGGCCCTAATCCGGCATTCAAAGACGCTACCGGAGCGCTGTTGGGCGGTACCAATATGGCAGCGGTGCATTT
GGCCAACGCCGTCGGCGGTAACTTCTTCCTCGGGTTTATTTCGGCGGTCGCCTTTGCCACCATTCTGGCGGTGGTTGCCG
GCCTGACGCTGGCAGGAGCTTCTGCGGTATCTCATGACTTGTACGCCAGCGTGATTAAAAACGGTAAGGCGACCGAACGT
GATGAACTGCGGGTTTCCAAAATTACCGTGGTGATCCTGGGGATCGTGGCCATTGCACTGGGGATTTTGTTCGAGAAACA
GAATATCGCCTTTATGGTCGGGCTGGCCTTCTCGATTGCTGCCAGTTGTAACTTCCCGATTATCATTCTTTCAATGTATT
GGTCACGCCTGACTACGCGCGGCGCCATGATCGGCGGCTGGTTAGGTCTGCTGACGGCGGTGATCCTGATGATCCTCGGC
CCAACTATCTGGGTGCAGATCCTGGGGCATGAGAAGGCCATTTATCCTTATGAATATCCGGCGTTGTTCTCGATGATTGT
CGCGTTCGTCGGCACCTGGCTGTTCTCGGTCACCGACAGCTCATTGGCTGGGCAGCAGGAGCGTGAGCGCTTCCGTTTCC
AATTTGTACGTTCGCAAACCGGCCTGGGGATTTCCCAGGGCAGTTCGCATTAA

Upstream 100 bases:

>100_bases
GCCTGATCGTGATCTCTTTCGTGTTGACCGGGATCTATGTATTCCGCGCCAACGGCGAGTTCGATCGCCTGACTGCAGAA
GTCTTGCGTGAGGTGAAGAA

Downstream 100 bases:

>100_bases
AATAAAACCGTGGGTTCAGCATGCTGAACCCACTTTTTATTATCACTGACAGCAAAAAACTGCCCCTAACTGTCTGTCAG
TCACGTCACTCTCCGCTAAC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MKPLLSVAALLMLPGLAFADAISGEVHRQPLNIQAIVMFVLFVGATLYITYWASKRTRSRQDYYTAGGKITGLQNGLAIA
GDFMSAASFLGISALVYTSGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLKQKPIRTLSACGSLVVVAL
YLIAQMVGAGKLIQLLFGLNYHVAVILVGILMVLYVLFGGMLATTWVQIIKAVLLLAGASFMALMVMKSVNFDFNTLFAE
AVKVHPKGIAIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAI
LLVGPNPAFKDATGALLGGTNMAAVHLANAVGGNFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKNGKATER
DELRVSKITVVILGIVAIALGILFEKQNIAFMVGLAFSIAASCNFPIIILSMYWSRLTTRGAMIGGWLGLLTAVILMILG
PTIWVQILGHEKAIYPYEYPALFSMIVAFVGTWLFSVTDSSLAGQQERERFRFQFVRSQTGLGISQGSSH

Sequences:

>Translated_550_residues
MKPLLSVAALLMLPGLAFADAISGEVHRQPLNIQAIVMFVLFVGATLYITYWASKRTRSRQDYYTAGGKITGLQNGLAIA
GDFMSAASFLGISALVYTSGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLKQKPIRTLSACGSLVVVAL
YLIAQMVGAGKLIQLLFGLNYHVAVILVGILMVLYVLFGGMLATTWVQIIKAVLLLAGASFMALMVMKSVNFDFNTLFAE
AVKVHPKGIAIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAI
LLVGPNPAFKDATGALLGGTNMAAVHLANAVGGNFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKNGKATER
DELRVSKITVVILGIVAIALGILFEKQNIAFMVGLAFSIAASCNFPIIILSMYWSRLTTRGAMIGGWLGLLTAVILMILG
PTIWVQILGHEKAIYPYEYPALFSMIVAFVGTWLFSVTDSSLAGQQERERFRFQFVRSQTGLGISQGSSH
>Mature_550_residues
MKPLLSVAALLMLPGLAFADAISGEVHRQPLNIQAIVMFVLFVGATLYITYWASKRTRSRQDYYTAGGKITGLQNGLAIA
GDFMSAASFLGISALVYTSGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLKQKPIRTLSACGSLVVVAL
YLIAQMVGAGKLIQLLFGLNYHVAVILVGILMVLYVLFGGMLATTWVQIIKAVLLLAGASFMALMVMKSVNFDFNTLFAE
AVKVHPKGIAIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAI
LLVGPNPAFKDATGALLGGTNMAAVHLANAVGGNFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKNGKATER
DELRVSKITVVILGIVAIALGILFEKQNIAFMVGLAFSIAASCNFPIIILSMYWSRLTTRGAMIGGWLGLLTAVILMILG
PTIWVQILGHEKAIYPYEYPALFSMIVAFVGTWLFSVTDSSLAGQQERERFRFQFVRSQTGLGISQGSSH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=535, Percent_Identity=24.6728971962617, Blast_Score=100, Evalue=5e-21,
Organism=Escherichia coli, GI1790503, Length=550, Percent_Identity=81.4545454545455, Blast_Score=903, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=456, Percent_Identity=25.219298245614, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082237, Length=420, Percent_Identity=21.1904761904762, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58985; Mature: 58985

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLLSVAALLMLPGLAFADAISGEVHRQPLNIQAIVMFVLFVGATLYITYWASKRTRSR
CCHHHHHHHHHHHCCHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHEEEEHHHHCCCC
QDYYTAGGKITGLQNGLAIAGDFMSAASFLGISALVYTSGYDGLIYSIGFLIGWPIILFL
CHHEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IAERLRNLGRYTFADVASYRLKQKPIRTLSACGSLVVVALYLIAQMVGAGKLIQLLFGLN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
YHVAVILVGILMVLYVLFGGMLATTWVQIIKAVLLLAGASFMALMVMKSVNFDFNTLFAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AVKVHPKGIAIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFY
HHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHH
ATGFIGYFYILTFIIGFGAILLVGPNPAFKDATGALLGGTNMAAVHLANAVGGNFFLGFI
HHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
SAVAFATILAVVAGLTLAGASAVSHDLYASVIKNGKATERDELRVSKITVVILGIVAIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GILFEKQNIAFMVGLAFSIAASCNFPIIILSMYWSRLTTRGAMIGGWLGLLTAVILMILG
HHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
PTIWVQILGHEKAIYPYEYPALFSMIVAFVGTWLFSVTDSSLAGQQERERFRFQFVRSQT
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHC
GLGISQGSSH
CCCCCCCCCC
>Mature Secondary Structure
MKPLLSVAALLMLPGLAFADAISGEVHRQPLNIQAIVMFVLFVGATLYITYWASKRTRSR
CCHHHHHHHHHHHCCHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHEEEEHHHHCCCC
QDYYTAGGKITGLQNGLAIAGDFMSAASFLGISALVYTSGYDGLIYSIGFLIGWPIILFL
CHHEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IAERLRNLGRYTFADVASYRLKQKPIRTLSACGSLVVVALYLIAQMVGAGKLIQLLFGLN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
YHVAVILVGILMVLYVLFGGMLATTWVQIIKAVLLLAGASFMALMVMKSVNFDFNTLFAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AVKVHPKGIAIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFY
HHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHH
ATGFIGYFYILTFIIGFGAILLVGPNPAFKDATGALLGGTNMAAVHLANAVGGNFFLGFI
HHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
SAVAFATILAVVAGLTLAGASAVSHDLYASVIKNGKATERDELRVSKITVVILGIVAIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GILFEKQNIAFMVGLAFSIAASCNFPIIILSMYWSRLTTRGAMIGGWLGLLTAVILMILG
HHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
PTIWVQILGHEKAIYPYEYPALFSMIVAFVGTWLFSVTDSSLAGQQERERFRFQFVRSQT
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHC
GLGISQGSSH
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA