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The map label for this gene is wecF

Identifier: 157368419

GI number: 157368419

Start: 191867

End: 192952

Strand: Direct

Name: wecF

Synonym: Spro_0170

Alternate gene names: 157368419

Gene position: 191867-192952 (Clockwise)

Preceding gene: 157368418

Following gene: 157368420

Centisome position: 3.52

GC content: 56.91

Gene sequence:

>1086_bases
ATGACTACACTGATTCACGTATTGGGATCTGACATCCCGCATCACAATCAGACGGTGCTGCGTTTCTTCAACGACGTGTT
GGCGAAGCGCTTGCCGTCCGATCAGACGCGTCATTTCATGGTGGCTGCCAAAGATGCCGCTGCGTTAGGGCCGTTCCCCG
AGCTGAACCTTGAATGTCATCCGGACAAGAAAAGCCTGGCGATGGCGGTTATAGCCCGTGCTCAGGCCGATCGCGACCAG
CGTTTCTTCTTCCATGGGCAGTTTAATCCGACGCTGTGGCTGGCATTGCTGAGCGGCAAAATCAAAGCCCATCAGGTCAG
CTGGCATATCTGGGGTGCTGACCTGTATGAAAACGCCACCAGTTGGAAATTCCGCCTGTTCTATTTGCTGCGCCGCATTG
CACAAGGCCGCGTCGGACGCGTATTCGCTACCCGTGGCGATGTGATCCACTATCAACAGCGGCATGCGCGTGTGCCTGCC
TCCCTGCTGTATTTCCCGACGCGGATGGATCCGGCATTGACCGGTATCAGCGTCGAGAAAAATCTGGCCGGGCCGATGAC
CATTCTGGTGGGTAACTCCGGCGATCGCACCAATCGGCACGTTGAGGCACTGAAAGCGATTCATCAACAGTTTGGCGCGG
ATGTACGCGTGATCCTGCCGATGGGTTATCCGGCCAACAACGAGGCTTATATTGAACAGGTCCGCACTGCCGGGCTGGCG
CTGTTCAGTGCCAGCAATCTGCAGGTGCTGACGCAGCAGGTGGCGTTCGACGACTACCTGAACATTCTGCGCGAGTGCGA
TCTTGGCTACTTTATCTTTAACCGCCAACAGGGTATCGGCACGCTTTGCCTGTTGATCCAGTTTGGCGTGCCGTTCGTGC
TGAGCCGGCAGAACCCGTTCTGGCAGGATCTGGCGGAGCAGCACCTGCCGGTGCTGTTCTACGGTGATTCTCTGGATGAG
GCGGTAGTGCGTGAAGCGCAACGCCAACTGGCGTCAGTGGACAAGCAGGAGATCGCCTTCTTTAATCCCAACTACGTTGA
TGGCTGGCAACAGGCATTAGCCCTGGCGGCAGGGGATAACTCATGA

Upstream 100 bases:

>100_bases
CTTTGCACGGCGCGCTGGGTGCGGCACAGGCCTACATGGCAACCTACATCGTGTATTTCACGCTCTGTAGCTGCGTATTT
ATTCTTTATCGTAGACGAGT

Downstream 100 bases:

>100_bases
CGCTGGCGCAATTTGGCGGGTTATTTGTCGTCTACCTGATTGGCACGTTGTTTGTTCTGACGTTGACCTATCAGGAGTTT
CGGCGCGTCCGTTTTAACTT

Product: 4-alpha-L-fucosyltransferase

Products: NA

Alternate protein names: TDP-Fuc4NAc:lipid II Fuc4NAc transferase; Fuc4NAc transferase

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTTLIHVLGSDIPHHNQTVLRFFNDVLAKRLPSDQTRHFMVAAKDAAALGPFPELNLECHPDKKSLAMAVIARAQADRDQ
RFFFHGQFNPTLWLALLSGKIKAHQVSWHIWGADLYENATSWKFRLFYLLRRIAQGRVGRVFATRGDVIHYQQRHARVPA
SLLYFPTRMDPALTGISVEKNLAGPMTILVGNSGDRTNRHVEALKAIHQQFGADVRVILPMGYPANNEAYIEQVRTAGLA
LFSASNLQVLTQQVAFDDYLNILRECDLGYFIFNRQQGIGTLCLLIQFGVPFVLSRQNPFWQDLAEQHLPVLFYGDSLDE
AVVREAQRQLASVDKQEIAFFNPNYVDGWQQALALAAGDNS

Sequences:

>Translated_361_residues
MTTLIHVLGSDIPHHNQTVLRFFNDVLAKRLPSDQTRHFMVAAKDAAALGPFPELNLECHPDKKSLAMAVIARAQADRDQ
RFFFHGQFNPTLWLALLSGKIKAHQVSWHIWGADLYENATSWKFRLFYLLRRIAQGRVGRVFATRGDVIHYQQRHARVPA
SLLYFPTRMDPALTGISVEKNLAGPMTILVGNSGDRTNRHVEALKAIHQQFGADVRVILPMGYPANNEAYIEQVRTAGLA
LFSASNLQVLTQQVAFDDYLNILRECDLGYFIFNRQQGIGTLCLLIQFGVPFVLSRQNPFWQDLAEQHLPVLFYGDSLDE
AVVREAQRQLASVDKQEIAFFNPNYVDGWQQALALAAGDNS
>Mature_360_residues
TTLIHVLGSDIPHHNQTVLRFFNDVLAKRLPSDQTRHFMVAAKDAAALGPFPELNLECHPDKKSLAMAVIARAQADRDQR
FFFHGQFNPTLWLALLSGKIKAHQVSWHIWGADLYENATSWKFRLFYLLRRIAQGRVGRVFATRGDVIHYQQRHARVPAS
LLYFPTRMDPALTGISVEKNLAGPMTILVGNSGDRTNRHVEALKAIHQQFGADVRVILPMGYPANNEAYIEQVRTAGLAL
FSASNLQVLTQQVAFDDYLNILRECDLGYFIFNRQQGIGTLCLLIQFGVPFVLSRQNPFWQDLAEQHLPVLFYGDSLDEA
VVREAQRQLASVDKQEIAFFNPNYVDGWQQALALAAGDNS

Specific function: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential)

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 56 family

Homologues:

Organism=Escherichia coli, GI48994971, Length=357, Percent_Identity=65.8263305322129, Blast_Score=495, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WECF_SERP5 (A8G840)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476408.1
- STRING:   A8G840
- GeneID:   5605302
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0170
- eggNOG:   NOG04337
- HOGENOM:   HBG296660
- OMA:   IVPMGYP
- ProtClustDB:   PRK02797
- BioCyc:   SPRO399741:SPRO_0170-MONOMER
- HAMAP:   MF_01002
- InterPro:   IPR009993

Pfam domain/function: PF07429 Fuc4NAc_transf

EC number: NA

Molecular weight: Translated: 40757; Mature: 40626

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLIHVLGSDIPHHNQTVLRFFNDVLAKRLPSDQTRHFMVAAKDAAALGPFPELNLECH
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHCCCCCCCCEEEC
PDKKSLAMAVIARAQADRDQRFFFHGQFNPTLWLALLSGKIKAHQVSWHIWGADLYENAT
CCHHHHHHHHHHHHHCCCCCEEEEEECCCHHEEEEEHHCCCEEEEEEEEEECHHHHCCCC
SWKFRLFYLLRRIAQGRVGRVFATRGDVIHYQQRHARVPASLLYFPTRMDPALTGISVEK
CHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHHHHHCCCHHHEEECCCCCCHHCCCEECC
NLAGPMTILVGNSGDRTNRHVEALKAIHQQFGADVRVILPMGYPANNEAYIEQVRTAGLA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHEE
LFSASNLQVLTQQVAFDDYLNILRECDLGYFIFNRQQGIGTLCLLIQFGVPFVLSRQNPF
EEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCH
WQDLAEQHLPVLFYGDSLDEAVVREAQRQLASVDKQEIAFFNPNYVDGWQQALALAAGDN
HHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHCCCC
S
C
>Mature Secondary Structure 
TTLIHVLGSDIPHHNQTVLRFFNDVLAKRLPSDQTRHFMVAAKDAAALGPFPELNLECH
CEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHCCCCCCCCEEEC
PDKKSLAMAVIARAQADRDQRFFFHGQFNPTLWLALLSGKIKAHQVSWHIWGADLYENAT
CCHHHHHHHHHHHHHCCCCCEEEEEECCCHHEEEEEHHCCCEEEEEEEEEECHHHHCCCC
SWKFRLFYLLRRIAQGRVGRVFATRGDVIHYQQRHARVPASLLYFPTRMDPALTGISVEK
CHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHHHHHCCCHHHEEECCCCCCHHCCCEECC
NLAGPMTILVGNSGDRTNRHVEALKAIHQQFGADVRVILPMGYPANNEAYIEQVRTAGLA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHEE
LFSASNLQVLTQQVAFDDYLNILRECDLGYFIFNRQQGIGTLCLLIQFGVPFVLSRQNPF
EEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCH
WQDLAEQHLPVLFYGDSLDEAVVREAQRQLASVDKQEIAFFNPNYVDGWQQALALAAGDN
HHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA