| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is fabG [H]
Identifier: 157368376
GI number: 157368376
Start: 136509
End: 137267
Strand: Direct
Name: fabG [H]
Synonym: Spro_0127
Alternate gene names: 157368376
Gene position: 136509-137267 (Clockwise)
Preceding gene: 157368373
Following gene: 157368378
Centisome position: 2.51
GC content: 61.92
Gene sequence:
>759_bases ATGAATTTGCATCTGCAGGGGCGTATCGCGTTGGTGACCGGTGCCAGCGAAGGGATTGGCGCAGGCATGGTTCGGGTATT GGCGGCGCAGGGGGTGACTGTGGTGGCGACGGCGCGCCGGGAAGACCGTTTGCAGACCCTGGCGGATGAGGTTGAGCAAG CCGGTGGCATACGGCCCTATGTCATCGCGGCAGATATCACCCAGACACAAGCGCTCGACAGCATGCTGGCGCTGGCGCTA CAGCAGTTCGGGACCATCGATATTGTGATTAATGCGGTCGGCGGGGCTCGCCCAACCTCGTTGAGCGAAGGCGATGCCGG TTGGGAAGAAGCCTTTGCCCTGAACTTTACCCCGGCGCGTCGGATAACCCATGCGTTGCTGCCCCGGATGCTGGCGCAGG GCTGGGGACGGGTGATCAACATCAGTGGCTCGATGGAGCCGCGCAGTTTGAACGCTGCCACCGCCGCCAAGGGGGCGTTG CACCTATGGGCCAAGGGGCTGGCAGGCAACGTGGCGGCGCAAGGGGTTACGGTTAATACGCTGCAGCCCGGGCGGATTAA TAGCGAGCAGGTGCGTGAAAAACTGCACCCGACGGAGGCCGCCCGCCAGGCGTTTATCGAACAGAATATCCCGATTGGCT ATTTTGGTGAGCCGGAGGATATGGCCTATCTGGCCGCGTTTCTTTGTTCCCCGCAGGCGCGCTATATCACCGGGGCGGTG ATCCCGGTGGATGGCGGTATGCATTATTTTGCGCACTGA
Upstream 100 bases:
>100_bases ACAGTATTGCCGCGAGTTTACGGAATATTCACACAGACTGGGACGTGATTCAATGGCGTTATCTTTGTAACCAGATTGAA TTATTCAATTAGGATATCTT
Downstream 100 bases:
>100_bases AGTGGTTGTCGGCTATGCCGCATCGCTTTCCCGATAGCGCCGGCGGGCATGTTCAAACCAGCTTGCCGGGACGTTATGCG GTGGCAATTGCAGCCTTTCC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 252; Mature: 252
Protein sequence:
>252_residues MNLHLQGRIALVTGASEGIGAGMVRVLAAQGVTVVATARREDRLQTLADEVEQAGGIRPYVIAADITQTQALDSMLALAL QQFGTIDIVINAVGGARPTSLSEGDAGWEEAFALNFTPARRITHALLPRMLAQGWGRVINISGSMEPRSLNAATAAKGAL HLWAKGLAGNVAAQGVTVNTLQPGRINSEQVREKLHPTEAARQAFIEQNIPIGYFGEPEDMAYLAAFLCSPQARYITGAV IPVDGGMHYFAH
Sequences:
>Translated_252_residues MNLHLQGRIALVTGASEGIGAGMVRVLAAQGVTVVATARREDRLQTLADEVEQAGGIRPYVIAADITQTQALDSMLALAL QQFGTIDIVINAVGGARPTSLSEGDAGWEEAFALNFTPARRITHALLPRMLAQGWGRVINISGSMEPRSLNAATAAKGAL HLWAKGLAGNVAAQGVTVNTLQPGRINSEQVREKLHPTEAARQAFIEQNIPIGYFGEPEDMAYLAAFLCSPQARYITGAV IPVDGGMHYFAH >Mature_252_residues MNLHLQGRIALVTGASEGIGAGMVRVLAAQGVTVVATARREDRLQTLADEVEQAGGIRPYVIAADITQTQALDSMLALAL QQFGTIDIVINAVGGARPTSLSEGDAGWEEAFALNFTPARRITHALLPRMLAQGWGRVINISGSMEPRSLNAATAAKGAL HLWAKGLAGNVAAQGVTVNTLQPGRINSEQVREKLHPTEAARQAFIEQNIPIGYFGEPEDMAYLAAFLCSPQARYITGAV IPVDGGMHYFAH
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=28.7449392712551, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=28.0632411067194, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=28.4584980237154, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=28.3400809716599, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=27.3092369477912, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4503301, Length=253, Percent_Identity=28.8537549407115, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=26.4, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=29.4354838709677, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI226371731, Length=185, Percent_Identity=29.1891891891892, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=25.2032520325203, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=28.8793103448276, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=27.363184079602, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=32.8, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=30.1204819277108, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=29.5275590551181, Blast_Score=95, Evalue=3e-21, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=30.0395256916996, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=26.8774703557312, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=25, Blast_Score=92, Evalue=5e-20, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=28.4552845528455, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=31.5217391304348, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=28.8, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=26.5151515151515, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=26.3565891472868, Blast_Score=63, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=30.6513409961686, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=29.3650793650794, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=27.5471698113208, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=28.7313432835821, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=28.4615384615385, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=27.9245283018868, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=30.3030303030303, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=27.2, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=27.6923076923077, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=27.0992366412214, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17538486, Length=258, Percent_Identity=28.2945736434109, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=27.9245283018868, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=29.9212598425197, Blast_Score=90, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=28.1368821292776, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=28.0155642023346, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=30.1587301587302, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=27.9245283018868, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=26.4367816091954, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=27.8195488721804, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=28.4615384615385, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=26.953125, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=24.812030075188, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=26.8774703557312, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=28.0632411067194, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=25.0965250965251, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=25.6704980842912, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17558006, Length=223, Percent_Identity=26.0089686098655, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=32.48730964467, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=29.2307692307692, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=23.5521235521236, Blast_Score=74, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=230, Percent_Identity=25.2173913043478, Blast_Score=68, Evalue=2e-12, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=29.2490118577075, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=30.1960784313725, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=29.7619047619048, Blast_Score=98, Evalue=6e-21, Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=26.4591439688716, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=28.8, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=28.4974093264249, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=27.6381909547739, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24584744, Length=189, Percent_Identity=28.042328042328, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI28574402, Length=189, Percent_Identity=28.042328042328, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24644337, Length=264, Percent_Identity=25.7575757575758, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007238, Length=86, Percent_Identity=39.5348837209302, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI116007236, Length=86, Percent_Identity=39.5348837209302, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26735; Mature: 26735
Theoretical pI: Translated: 6.52; Mature: 6.52
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNLHLQGRIALVTGASEGIGAGMVRVLAAQGVTVVATARREDRLQTLADEVEQAGGIRPY CCEEECEEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCCE VIAADITQTQALDSMLALALQQFGTIDIVINAVGGARPTSLSEGDAGWEEAFALNFTPAR EEEECCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHEEEECCCHHH RITHALLPRMLAQGWGRVINISGSMEPRSLNAATAAKGALHLWAKGLAGNVAAQGVTVNT HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCEEEEC LQPGRINSEQVREKLHPTEAARQAFIEQNIPIGYFGEPEDMAYLAAFLCSPQARYITGAV CCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE IPVDGGMHYFAH EECCCCCHHCCC >Mature Secondary Structure MNLHLQGRIALVTGASEGIGAGMVRVLAAQGVTVVATARREDRLQTLADEVEQAGGIRPY CCEEECEEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCCE VIAADITQTQALDSMLALALQQFGTIDIVINAVGGARPTSLSEGDAGWEEAFALNFTPAR EEEECCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHEEEECCCHHH RITHALLPRMLAQGWGRVINISGSMEPRSLNAATAAKGALHLWAKGLAGNVAAQGVTVNT HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCEEEEC LQPGRINSEQVREKLHPTEAARQAFIEQNIPIGYFGEPEDMAYLAAFLCSPQARYITGAV CCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE IPVDGGMHYFAH EECCCCCHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]