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The map label for this gene is fdoG [H]

Identifier: 157368333

GI number: 157368333

Start: 87649

End: 90060

Strand: Direct

Name: fdoG [H]

Synonym: Spro_0084

Alternate gene names: 157368333

Gene position: 87649-90060 (Clockwise)

Preceding gene: 157368332

Following gene: 157368334

Centisome position: 1.61

GC content: 58.25

Gene sequence:

>2412_bases
ATGACCAACCACTGGGTTGATATCAAGAACGCGAATCTGATTATCGTCATGGGCGGTAATGCGGCGGAAGCGCATCCGGT
GGGGTTCCGCTGGGCGATGGAAGCCAAAATACACAATAAAGCCAAGCTGATCGTCATCGATCCGCGCTTTACCCGTACCG
CATCGGTGGCGGATTTCTACACGCCGATCCGTTCCGGGACCGACATTGCCTTCCTGTCGGGCGTGTTGCTATACCTGATG
ACCAACGACAAGATTAACCGCGAATACGTCCACGCCTATACCAACGCCAGCCTGCTGGTGCGGGAAGACTTTACCTTTGA
AGACGGCCTGTTCAGCGGTTATGACGCGGAAAACCGCAAGTACGATAAAACCACCTGGAACTACCAGTTCGATGAAAACG
GCTTTGCCAAGCGCGATCTGACGCTGCAGGACCCGCGTTGCGTGTGGAACCTGCTGAAACAGCACGTCAGCCGTTATACG
CCGGAAGTGGTGAACAACATTTGCGGTACGCCGACCGAAGACTTCATCAAGGTCTGTGAATACATCGCCGAAACCTGCGT
GGCGGATAAAACCGCGTCGTTCCTGTACGCCCTGGGCTGGACTCAGCACTCGGTCGGTTCGCAGAACATCCGCACCATGG
CGATGATCCAGCTGTTGCTCGGAAACATGGGCATGGCGGGTGGCGGCGTCAACGCGCTGCGTGGCCACTCCAACATTCAG
GGTCTGACCGACCTGGGCCTGCTGTCGCAGAGCCTGCCGGGCTATATGACGCTGCCGTCGGAGAAACAGACCGATATCGA
CACCTACCTGAAAGCCAATACGCCGAAGGCGTTGCTGCCGGGCCAGGTGAACTACTGGAGCAACTACCCGAAATTCTTCG
TCAGCATGATGAAGAGCTTCTATGGCGACAAGGCGCAGAAGGAAAACGGTTGGGGCTTTGACTGGCTGCCGAAGTGGGAC
AAAGGCTACGACGTGCTGCAGTACTTCGAGCTGATGTCGCAAGGCAAGGTCAACGGTTACTTCTGCCAGGGCTTTAACCC
GGTGGCGTCGTTCCCGAACAAGAACAAGGTGGTGGCCTCACTGTCAAAACTGAAGTTCCTGGTGACCATTGATCCGCTCA
ATACCGAAACCTCCAACTTCTGGCAGAACCACGGCGAGTTCAACGACGTCGATCCGTCGAAGATTCAGACCGAGGTATTC
CGGCTGCCGTCTAGCTGTTTCGCCGAAGAGAACGGTTCGATCGTGAACTCTGGGCGCTGGCTGCAATGGCACTGGAAAGG
GGCTGATGCCCCAGGCGAGGCTAAGCACGACGGGGAAATCCTGGCGGGCATCTTCATCCGTCTGCGTGAGATGTATGCGC
GTGACGGCGGTGCAGTACCGGAGCAGGTACTGAACATGACCTGGGATTACCTGACGCCGGAAGATCCTGCTTCGGAAGAA
GTGGCGATGGAAAGCAACGGTAAGGCGCTGGCGGACGTTCTCGACGCCGACGGCAAAGTGCTGGCGAAAAAAGGTGAGCA
GCTCAGCACCTTTGCCCACCTGCGTGACGACGGCACGACGGCCAGCGGCTGTTGGATCTTCGCCGGTAGCTGGACGCAGG
CCGGTAACCAGATGGCGCGGCGCGATAACGCCGATCCGTCCGGCCTCGGCAATACGCTGGGTTGGGCCTGGGCCTGGCCG
CTCAACCGCCGCATTCTGTATAACCGTGCTTCCGCTGACCCGCAGGGCAAGCCCTGGGATCCAAAACGTCAGTTGCTGGA
ATGGGACGGCACCAAGTGGGGCGGGGTGGATATCCCGGACTACAGCGCCGCCGCACCGGGCAGTGACGTGGGGCCATTCA
TCATGCAGCCGGAAGGCATGGGCCGTCTGTTTGCCACCGATAAAATGGCCGAAGGGCCGTTCCCGGAACACTACGAGCCG
TTTGAAACGCCGCTCGGTACCAACCCGCTGCACCCGAACGTGGTTTCCAACCCGGCGGCAAGGGTGTTCAAGGACGATCT
GGCGGCAATGGGCACTTCAGACAAGTTCCCGTATGTCGGCACTACCTACCGGTTGACCGAGCATTTCCACTACTGGACCA
AGCACGCGATACTCAACGCCATCGCGCAGCCGGAACAGTTTGTGGAGATTGGCGAGAAACTGGCGGCGAAAAAAGGCATT
CAGCACGGTGATACGGTGAAGGTCAGCTCCAACCGCGGCTTTATCAAGGCCAAGGCGGTGGTGACCAAACGTATCCGCAC
CCTGCAGGTGAACGGCCAGGACGTCGACACCATAGGTATCCCGATCCACTGGGGTTACGAAGGGGTGGCGAAGAAAGGCT
TTATTGCCAACACGCTGACGCCGTTTGTCGGTGATGCCAATACGCAAACGCCAGAGTTCAAGGCGTTCCTGGTCAACGTG
GAAAAGGTGTAA

Upstream 100 bases:

>100_bases
ATTTAGTCGCGCTCTCGGCATGCTTGCCGTAGACAACCAAGCACGTGTCTGACACGGACCAACGGTAGCAAGTCTTGCTC
CAACATTTGGTCGCGGTGCG

Downstream 100 bases:

>100_bases
CGGAGACGAATTATGGCAATGCAATCTCAGGACATCATTCGTAAATCCGCCACCAATGGTTTCACGCCGGCGCCGCGCGC
CCGTGACCACCAGGAGGAAG

Product: formate dehydrogenase subunit alpha

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 803; Mature: 802

Protein sequence:

>803_residues
MTNHWVDIKNANLIIVMGGNAAEAHPVGFRWAMEAKIHNKAKLIVIDPRFTRTASVADFYTPIRSGTDIAFLSGVLLYLM
TNDKINREYVHAYTNASLLVREDFTFEDGLFSGYDAENRKYDKTTWNYQFDENGFAKRDLTLQDPRCVWNLLKQHVSRYT
PEVVNNICGTPTEDFIKVCEYIAETCVADKTASFLYALGWTQHSVGSQNIRTMAMIQLLLGNMGMAGGGVNALRGHSNIQ
GLTDLGLLSQSLPGYMTLPSEKQTDIDTYLKANTPKALLPGQVNYWSNYPKFFVSMMKSFYGDKAQKENGWGFDWLPKWD
KGYDVLQYFELMSQGKVNGYFCQGFNPVASFPNKNKVVASLSKLKFLVTIDPLNTETSNFWQNHGEFNDVDPSKIQTEVF
RLPSSCFAEENGSIVNSGRWLQWHWKGADAPGEAKHDGEILAGIFIRLREMYARDGGAVPEQVLNMTWDYLTPEDPASEE
VAMESNGKALADVLDADGKVLAKKGEQLSTFAHLRDDGTTASGCWIFAGSWTQAGNQMARRDNADPSGLGNTLGWAWAWP
LNRRILYNRASADPQGKPWDPKRQLLEWDGTKWGGVDIPDYSAAAPGSDVGPFIMQPEGMGRLFATDKMAEGPFPEHYEP
FETPLGTNPLHPNVVSNPAARVFKDDLAAMGTSDKFPYVGTTYRLTEHFHYWTKHAILNAIAQPEQFVEIGEKLAAKKGI
QHGDTVKVSSNRGFIKAKAVVTKRIRTLQVNGQDVDTIGIPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKAFLVNV
EKV

Sequences:

>Translated_803_residues
MTNHWVDIKNANLIIVMGGNAAEAHPVGFRWAMEAKIHNKAKLIVIDPRFTRTASVADFYTPIRSGTDIAFLSGVLLYLM
TNDKINREYVHAYTNASLLVREDFTFEDGLFSGYDAENRKYDKTTWNYQFDENGFAKRDLTLQDPRCVWNLLKQHVSRYT
PEVVNNICGTPTEDFIKVCEYIAETCVADKTASFLYALGWTQHSVGSQNIRTMAMIQLLLGNMGMAGGGVNALRGHSNIQ
GLTDLGLLSQSLPGYMTLPSEKQTDIDTYLKANTPKALLPGQVNYWSNYPKFFVSMMKSFYGDKAQKENGWGFDWLPKWD
KGYDVLQYFELMSQGKVNGYFCQGFNPVASFPNKNKVVASLSKLKFLVTIDPLNTETSNFWQNHGEFNDVDPSKIQTEVF
RLPSSCFAEENGSIVNSGRWLQWHWKGADAPGEAKHDGEILAGIFIRLREMYARDGGAVPEQVLNMTWDYLTPEDPASEE
VAMESNGKALADVLDADGKVLAKKGEQLSTFAHLRDDGTTASGCWIFAGSWTQAGNQMARRDNADPSGLGNTLGWAWAWP
LNRRILYNRASADPQGKPWDPKRQLLEWDGTKWGGVDIPDYSAAAPGSDVGPFIMQPEGMGRLFATDKMAEGPFPEHYEP
FETPLGTNPLHPNVVSNPAARVFKDDLAAMGTSDKFPYVGTTYRLTEHFHYWTKHAILNAIAQPEQFVEIGEKLAAKKGI
QHGDTVKVSSNRGFIKAKAVVTKRIRTLQVNGQDVDTIGIPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKAFLVNV
EKV
>Mature_802_residues
TNHWVDIKNANLIIVMGGNAAEAHPVGFRWAMEAKIHNKAKLIVIDPRFTRTASVADFYTPIRSGTDIAFLSGVLLYLMT
NDKINREYVHAYTNASLLVREDFTFEDGLFSGYDAENRKYDKTTWNYQFDENGFAKRDLTLQDPRCVWNLLKQHVSRYTP
EVVNNICGTPTEDFIKVCEYIAETCVADKTASFLYALGWTQHSVGSQNIRTMAMIQLLLGNMGMAGGGVNALRGHSNIQG
LTDLGLLSQSLPGYMTLPSEKQTDIDTYLKANTPKALLPGQVNYWSNYPKFFVSMMKSFYGDKAQKENGWGFDWLPKWDK
GYDVLQYFELMSQGKVNGYFCQGFNPVASFPNKNKVVASLSKLKFLVTIDPLNTETSNFWQNHGEFNDVDPSKIQTEVFR
LPSSCFAEENGSIVNSGRWLQWHWKGADAPGEAKHDGEILAGIFIRLREMYARDGGAVPEQVLNMTWDYLTPEDPASEEV
AMESNGKALADVLDADGKVLAKKGEQLSTFAHLRDDGTTASGCWIFAGSWTQAGNQMARRDNADPSGLGNTLGWAWAWPL
NRRILYNRASADPQGKPWDPKRQLLEWDGTKWGGVDIPDYSAAAPGSDVGPFIMQPEGMGRLFATDKMAEGPFPEHYEPF
ETPLGTNPLHPNVVSNPAARVFKDDLAAMGTSDKFPYVGTTYRLTEHFHYWTKHAILNAIAQPEQFVEIGEKLAAKKGIQ
HGDTVKVSSNRGFIKAKAVVTKRIRTLQVNGQDVDTIGIPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKAFLVNVE
KV

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=804, Percent_Identity=85.8208955223881, Blast_Score=1470, Evalue=0.0,
Organism=Escherichia coli, GI3868719, Length=803, Percent_Identity=76.587795765878, Blast_Score=1337, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=448, Percent_Identity=22.7678571428571, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI87081797, Length=237, Percent_Identity=26.5822784810127, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787870, Length=234, Percent_Identity=26.4957264957265, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 89577; Mature: 89446

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNHWVDIKNANLIIVMGGNAAEAHPVGFRWAMEAKIHNKAKLIVIDPRFTRTASVADFY
CCCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHH
TPIRSGTDIAFLSGVLLYLMTNDKINREYVHAYTNASLLVREDFTFEDGLFSGYDAENRK
HHHCCCCCHHHHHHHHEEEECCCCCCHHHEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
YDKTTWNYQFDENGFAKRDLTLQDPRCVWNLLKQHVSRYTPEVVNNICGTPTEDFIKVCE
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHH
YIAETCVADKTASFLYALGWTQHSVGSQNIRTMAMIQLLLGNMGMAGGGVNALRGHSNIQ
HHHHHHHHHHHHHHHHEECCCHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCC
GLTDLGLLSQSLPGYMTLPSEKQTDIDTYLKANTPKALLPGQVNYWSNYPKFFVSMMKSF
CHHHHHHHHHCCCCCEECCCCCCCCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
YGDKAQKENGWGFDWLPKWDKGYDVLQYFELMSQGKVNGYFCQGFNPVASFPNKNKVVAS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHCCCCCCHHHHH
LSKLKFLVTIDPLNTETSNFWQNHGEFNDVDPSKIQTEVFRLPSSCFAEENGSIVNSGRW
HHHEEEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCEEECCCE
LQWHWKGADAPGEAKHDGEILAGIFIRLREMYARDGGAVPEQVLNMTWDYLTPEDPASEE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHCCCCCCCCCCCC
VAMESNGKALADVLDADGKVLAKKGEQLSTFAHLRDDGTTASGCWIFAGSWTQAGNQMAR
EEECCCCCHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHH
RDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGKPWDPKRQLLEWDGTKWGGVDIPD
HCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
YSAAAPGSDVGPFIMQPEGMGRLFATDKMAEGPFPEHYEPFETPLGTNPLHPNVVSNPAA
CCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
RVFKDDLAAMGTSDKFPYVGTTYRLTEHFHYWTKHAILNAIAQPEQFVEIGEKLAAKKGI
HHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
QHGDTVKVSSNRGFIKAKAVVTKRIRTLQVNGQDVDTIGIPIHWGYEGVAKKGFIANTLT
CCCCEEEECCCCCEEEHHHHHHHCEEEEEECCCCCEEEEEEEECCCHHHHCCCCCHHCCC
PFVGDANTQTPEFKAFLVNVEKV
CCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure 
TNHWVDIKNANLIIVMGGNAAEAHPVGFRWAMEAKIHNKAKLIVIDPRFTRTASVADFY
CCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHH
TPIRSGTDIAFLSGVLLYLMTNDKINREYVHAYTNASLLVREDFTFEDGLFSGYDAENRK
HHHCCCCCHHHHHHHHEEEECCCCCCHHHEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
YDKTTWNYQFDENGFAKRDLTLQDPRCVWNLLKQHVSRYTPEVVNNICGTPTEDFIKVCE
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHH
YIAETCVADKTASFLYALGWTQHSVGSQNIRTMAMIQLLLGNMGMAGGGVNALRGHSNIQ
HHHHHHHHHHHHHHHHEECCCHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCC
GLTDLGLLSQSLPGYMTLPSEKQTDIDTYLKANTPKALLPGQVNYWSNYPKFFVSMMKSF
CHHHHHHHHHCCCCCEECCCCCCCCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
YGDKAQKENGWGFDWLPKWDKGYDVLQYFELMSQGKVNGYFCQGFNPVASFPNKNKVVAS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHCCCCCCHHHHH
LSKLKFLVTIDPLNTETSNFWQNHGEFNDVDPSKIQTEVFRLPSSCFAEENGSIVNSGRW
HHHEEEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCEEECCCE
LQWHWKGADAPGEAKHDGEILAGIFIRLREMYARDGGAVPEQVLNMTWDYLTPEDPASEE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHCCCCCCCCCCCC
VAMESNGKALADVLDADGKVLAKKGEQLSTFAHLRDDGTTASGCWIFAGSWTQAGNQMAR
EEECCCCCHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHH
RDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGKPWDPKRQLLEWDGTKWGGVDIPD
HCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
YSAAAPGSDVGPFIMQPEGMGRLFATDKMAEGPFPEHYEPFETPLGTNPLHPNVVSNPAA
CCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
RVFKDDLAAMGTSDKFPYVGTTYRLTEHFHYWTKHAILNAIAQPEQFVEIGEKLAAKKGI
HHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
QHGDTVKVSSNRGFIKAKAVVTKRIRTLQVNGQDVDTIGIPIHWGYEGVAKKGFIANTLT
CCCCEEEECCCCCEEEHHHHHHHCEEEEEECCCCCEEEEEEEECCCHHHHCCCCCHHCCC
PFVGDANTQTPEFKAFLVNVEKV
CCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]