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The map label for this gene is expR [H]

Identifier: 157368315

GI number: 157368315

Start: 67169

End: 67915

Strand: Direct

Name: expR [H]

Synonym: Spro_0066

Alternate gene names: 157368315

Gene position: 67169-67915 (Clockwise)

Preceding gene: 157368314

Following gene: 157368318

Centisome position: 1.23

GC content: 36.68

Gene sequence:

>747_bases
GTGTCAAATTCATTCTTCAATGATGAAACCATCAACACCACCATAAAAAATGATTTGGAAGGTAAACTTAGCGAGTATAG
TAACGTGAAGTACGCTTATGCCATAATGAATAAAAGAAATCCGGCGAACTTTGCGATTATTTCGAACGGAACTGAATGGT
TTGAATTTTATACAGAAAATAACTATCAATTTATCGACCCGGTTCTTATTACTGCTTCGCGCCGTATTACTCCGTTCTCC
TGGGATGAAAATATAATGATTGATCCAGGGTTAAAATTGCCAAGAATTTTTGATATGGCTAAGAATTACAATGTAGTTAA
TGGCTATACATTTGTGCTGCATGATCATAATCATAATTTGGTGGTGCTTTCTATTATGATTGATAAAAATTGCGACTATA
ATATAGAAGAAAGAATAATAGCCAACCAAGACAAACTTCAAATGCTGCTAATTACTACTCATGATAAGCTCACTGCATTT
TACAAGGAAATTAATAGCCCTACCTACTTTGACAAAATGAACAATAAAGGAATATTCTCGAAGCGAGAGAATGAGATAAT
TTACTGGGCAAGCATGGGTAAATCCTATCAGGAGATTGCGCTCATCCTGGGGATCAAGCTCACCACAATAAAATATCATA
TTGGTAATGCCGTCAAAAAATTAGGCGTTACCAACGCCAAACATGCTATCAGGCTAGGCGTTGAACTACAGCTGATCAGA
CCCGTGCTTCCTGACACGGAAGGTTAA

Upstream 100 bases:

>100_bases
TTAATAATTTAACCTGACTTTTTATCAGTTATGCCGCCAGCAATTTTTATGTTATAATTTTTATTAGCTAAGGATTTTTA
TTTTTTAAGGAGAGGGTTCA

Downstream 100 bases:

>100_bases
TGGCCAGGCATCGCGGTCCGGGGTTAAGCCAGGGTGGGCCAAGTTGATGCGATCGACCAATATCTGCTGGTTGCGATCGT
CAACCGGCATGTAAATCAGG

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSNSFFNDETINTTIKNDLEGKLSEYSNVKYAYAIMNKRNPANFAIISNGTEWFEFYTENNYQFIDPVLITASRRITPFS
WDENIMIDPGLKLPRIFDMAKNYNVVNGYTFVLHDHNHNLVVLSIMIDKNCDYNIEERIIANQDKLQMLLITTHDKLTAF
YKEINSPTYFDKMNNKGIFSKRENEIIYWASMGKSYQEIALILGIKLTTIKYHIGNAVKKLGVTNAKHAIRLGVELQLIR
PVLPDTEG

Sequences:

>Translated_248_residues
MSNSFFNDETINTTIKNDLEGKLSEYSNVKYAYAIMNKRNPANFAIISNGTEWFEFYTENNYQFIDPVLITASRRITPFS
WDENIMIDPGLKLPRIFDMAKNYNVVNGYTFVLHDHNHNLVVLSIMIDKNCDYNIEERIIANQDKLQMLLITTHDKLTAF
YKEINSPTYFDKMNNKGIFSKRENEIIYWASMGKSYQEIALILGIKLTTIKYHIGNAVKKLGVTNAKHAIRLGVELQLIR
PVLPDTEG
>Mature_247_residues
SNSFFNDETINTTIKNDLEGKLSEYSNVKYAYAIMNKRNPANFAIISNGTEWFEFYTENNYQFIDPVLITASRRITPFSW
DENIMIDPGLKLPRIFDMAKNYNVVNGYTFVLHDHNHNLVVLSIMIDKNCDYNIEERIIANQDKLQMLLITTHDKLTAFY
KEINSPTYFDKMNNKGIFSKRENEIIYWASMGKSYQEIALILGIKLTTIKYHIGNAVKKLGVTNAKHAIRLGVELQLIRP
VLPDTEG

Specific function: Functions as an OHLL responsive transcriptional regulator that acts in virulence (soft rot disease) through the activation of genes for plant tissue macerating enzymes [H]

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788224, Length=205, Percent_Identity=27.8048780487805, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR005143
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03472 Autoind_bind; PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 28678; Mature: 28547

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSFFNDETINTTIKNDLEGKLSEYSNVKYAYAIMNKRNPANFAIISNGTEWFEFYTEN
CCCCCCCCCCCCCHHHCCCCCHHHHHCCCEEEEEEECCCCCCCEEEEECCCEEEEEEECC
NYQFIDPVLITASRRITPFSWDENIMIDPGLKLPRIFDMAKNYNVVNGYTFVLHDHNHNL
CEEEECEEEEECCCCCCCCCCCCCEEECCCCCCCHHHHHHHCCEEECCEEEEEEECCCCE
VVLSIMIDKNCDYNIEERIIANQDKLQMLLITTHDKLTAFYKEINSPTYFDKMNNKGIFS
EEEEEEEECCCCCCHHHHEECCCCCEEEEEEECCHHHHHHHHHCCCCEEECCCCCCCCCC
KRENEIIYWASMGKSYQEIALILGIKLTTIKYHIGNAVKKLGVTNAKHAIRLGVELQLIR
CCCCCEEEEECCCCCHHHEEEEEEEEEEEEEEEHHHHHHHHCCCCCCCEEEECEEEEEEC
PVLPDTEG
CCCCCCCC
>Mature Secondary Structure 
SNSFFNDETINTTIKNDLEGKLSEYSNVKYAYAIMNKRNPANFAIISNGTEWFEFYTEN
CCCCCCCCCCCCHHHCCCCCHHHHHCCCEEEEEEECCCCCCCEEEEECCCEEEEEEECC
NYQFIDPVLITASRRITPFSWDENIMIDPGLKLPRIFDMAKNYNVVNGYTFVLHDHNHNL
CEEEECEEEEECCCCCCCCCCCCCEEECCCCCCCHHHHHHHCCEEECCEEEEEEECCCCE
VVLSIMIDKNCDYNIEERIIANQDKLQMLLITTHDKLTAFYKEINSPTYFDKMNNKGIFS
EEEEEEEECCCCCCHHHHEECCCCCEEEEEEECCHHHHHHHHHCCCCEEECCCCCCCCCC
KRENEIIYWASMGKSYQEIALILGIKLTTIKYHIGNAVKKLGVTNAKHAIRLGVELQLIR
CCCCCEEEEECCCCCHHHEEEEEEEEEEEEEEEHHHHHHHHCCCCCCCEEEECEEEEEEC
PVLPDTEG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA