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The map label for this gene is oxaA

Identifier: 157368277

GI number: 157368277

Start: 27544

End: 29181

Strand: Reverse

Name: oxaA

Synonym: Spro_0028

Alternate gene names: 157368277

Gene position: 29181-27544 (Counterclockwise)

Preceding gene: 157368278

Following gene: 157368276

Centisome position: 0.54

GC content: 55.13

Gene sequence:

>1638_bases
ATGGATTCGCAACGCAATCTTCTCCTCATCGCTCTGCTGTTCGTGTCTTTCATGATCTGGCAAGCCTGGCAAACGGACAA
TGCTCCGCAACCAGTCGCGCAGACCACGCAACAGACTTCGAACCCAGCTACCGGTGATGCCGCAAGCTCAGCAGTTCCAG
CCAGTGGCCAAGGTAAACTGATTACCGTAAACACTGACGTGCTGTCGCTGACCATCAACACCCGTGGTGGTGATATCGAG
CAGGCTAAACTGTTGGCCTACCCTGACACTCTGGGTTCATCGACGCCATTCCAGCTGCTGGAAACCACACCGGCATTTGT
CTATCAGGCGCAAAGCGGCCTGACCGGCAGAAACGGCCCGGATAACCCGGCAAATGGCGAACGTCCTCTGTTCCAGGCGG
CGCAGGACAGCTATACCCTGCCGGAAGGCCAGGAAGAGTTGCGCATCCCGCTGACCTTTACCGGTAAAGATGGCGCTATC
TACACCAAAACTTTCGTGCTCAAACGCAATCATTACGCGGTTGCCGTTGACTACAACGTCGACAACAAGAGCACCACTCC
GCTGGAACTGACCCTGTTCGGCCAACTGAAGCAGACCACCGAGCTGCCTAAGCACCGTGACACCGGCAGCAACAACTTTG
CCCTGCACACCTTCCGTGGCGCGGCTTACTCTTCCAGCGATGACAAATATCAGAAGTATGCGTTCGATAAGGACGAGAAC
CTGAGTGTCACCACCCAGGGCGGTTGGGTTGCAATGCTGCAACAATACTTCGCCACCGCGTGGGTACCGGCAACTCAGGG
TAGCAATACCTTCTATACCGCCAAGCCTGGCGACAACCTGTCTACCATCGGCTTCAAATCTACTCCGGTAGTGGTGCAGC
CTGGTGCGCAGCAGCAACTGAACGCCACCCTGTGGGTAGGCCCGGAACTGCAGGATCAGATGGCACAACTGGCGCCGCAT
CTGGACCTGACCGTGGATTACGGTTGGTTGTGGTTCATCTCCCAACCGCTGTTCAAACTGCTGAAGTTCATCCACGGCTT
TATCGGTAACTGGGGCTTCTCAATTATCATCATCACCTTCATCGTGCGCGGCATCATGTACCCGCTGACCAAAGCGCAGT
ACACCTCGATGGCGAAAATGCGCATGCTGCAGCCAAAACTGCAGGCGATGCGTGAGCGTATCGGTGATGACAAACAGCGC
ATGAGTCAGGAAATGATGGCGCTGTACAAGTCTGAGAAAGTGAATCCGTTGGGGGGTTGTCTGCCGCTGGTTATCCAGAT
GCCAATCTTCCTGGCGCTGTACTACATGTTGATGGGCTCGGTTGAGCTGCGCCACGCGCCGTTCGCTTTGTGGATCCACG
ACCTGTCGGCGCAAGACCCGTACTACATCTTGCCAATCCTGATGGGCGTGACGATGTTCTTCATTCAGAAGATGTCGCCG
ACCACCGTGACTGATCCGATGCAGCAGAAAATCATGACCTTCATGCCGGTGATCTTCACAGTGTTCTTCCTGTGGTTCCC
GTCCGGTCTGGTGCTGTACTACATCGTCAGTAACCTGGTGACCATCCTCCAGCAGCAGTTGATTTACCGCGGCCTGGAAA
AACGTGGTTTACACAGCCGCGACAAGAAAAAAACCTAA

Upstream 100 bases:

>100_bases
GTTGGTTAGCATTGAAACGCGTATTAAAATGCCACCCCTTGAACCCAGGTGGCGATGATCCCGTGCCGCCGAAACCCGAC
GATAACAGAGAACACTAACG

Downstream 100 bases:

>100_bases
GCGTATTGTAGGGGTTCGGCGCGCTGAACCCTTGCAGTAACACCAAGAGGCGGTCATTAGACCGCCTTTTTGCATATTGA
ATTGTCAGAGAAGAGAACCA

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MDSQRNLLLIALLFVSFMIWQAWQTDNAPQPVAQTTQQTSNPATGDAASSAVPASGQGKLITVNTDVLSLTINTRGGDIE
QAKLLAYPDTLGSSTPFQLLETTPAFVYQAQSGLTGRNGPDNPANGERPLFQAAQDSYTLPEGQEELRIPLTFTGKDGAI
YTKTFVLKRNHYAVAVDYNVDNKSTTPLELTLFGQLKQTTELPKHRDTGSNNFALHTFRGAAYSSSDDKYQKYAFDKDEN
LSVTTQGGWVAMLQQYFATAWVPATQGSNTFYTAKPGDNLSTIGFKSTPVVVQPGAQQQLNATLWVGPELQDQMAQLAPH
LDLTVDYGWLWFISQPLFKLLKFIHGFIGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDKQR
MSQEMMALYKSEKVNPLGGCLPLVIQMPIFLALYYMLMGSVELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSP
TTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTILQQQLIYRGLEKRGLHSRDKKKT

Sequences:

>Translated_545_residues
MDSQRNLLLIALLFVSFMIWQAWQTDNAPQPVAQTTQQTSNPATGDAASSAVPASGQGKLITVNTDVLSLTINTRGGDIE
QAKLLAYPDTLGSSTPFQLLETTPAFVYQAQSGLTGRNGPDNPANGERPLFQAAQDSYTLPEGQEELRIPLTFTGKDGAI
YTKTFVLKRNHYAVAVDYNVDNKSTTPLELTLFGQLKQTTELPKHRDTGSNNFALHTFRGAAYSSSDDKYQKYAFDKDEN
LSVTTQGGWVAMLQQYFATAWVPATQGSNTFYTAKPGDNLSTIGFKSTPVVVQPGAQQQLNATLWVGPELQDQMAQLAPH
LDLTVDYGWLWFISQPLFKLLKFIHGFIGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDKQR
MSQEMMALYKSEKVNPLGGCLPLVIQMPIFLALYYMLMGSVELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSP
TTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTILQQQLIYRGLEKRGLHSRDKKKT
>Mature_545_residues
MDSQRNLLLIALLFVSFMIWQAWQTDNAPQPVAQTTQQTSNPATGDAASSAVPASGQGKLITVNTDVLSLTINTRGGDIE
QAKLLAYPDTLGSSTPFQLLETTPAFVYQAQSGLTGRNGPDNPANGERPLFQAAQDSYTLPEGQEELRIPLTFTGKDGAI
YTKTFVLKRNHYAVAVDYNVDNKSTTPLELTLFGQLKQTTELPKHRDTGSNNFALHTFRGAAYSSSDDKYQKYAFDKDEN
LSVTTQGGWVAMLQQYFATAWVPATQGSNTFYTAKPGDNLSTIGFKSTPVVVQPGAQQQLNATLWVGPELQDQMAQLAPH
LDLTVDYGWLWFISQPLFKLLKFIHGFIGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDKQR
MSQEMMALYKSEKVNPLGGCLPLVIQMPIFLALYYMLMGSVELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSP
TTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTILQQQLIYRGLEKRGLHSRDKKKT

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=548, Percent_Identity=77.5547445255474, Blast_Score=877, Evalue=0.0,
Organism=Drosophila melanogaster, GI24662345, Length=207, Percent_Identity=25.6038647342995, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21356443, Length=207, Percent_Identity=25.6038647342995, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_SERP5 (A8G7P8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476266.1
- ProteinModelPortal:   A8G7P8
- SMR:   A8G7P8
- STRING:   A8G7P8
- GeneID:   5606327
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0028
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- ProtClustDB:   PRK01318
- BioCyc:   SPRO399741:SPRO_0028-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 61143; Mature: 61143

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2111d0c8)-; HASH(0x210e44c4)-; HASH(0x2005eb84)-; HASH(0x2108935c)-; HASH(0x21004bdc)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSQRNLLLIALLFVSFMIWQAWQTDNAPQPVAQTTQQTSNPATGDAASSAVPASGQGKL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEE
ITVNTDVLSLTINTRGGDIEQAKLLAYPDTLGSSTPFQLLETTPAFVYQAQSGLTGRNGP
EEEECCEEEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHCCHHHEEECCCCCCCCCCC
DNPANGERPLFQAAQDSYTLPEGQEELRIPLTFTGKDGAIYTKTFVLKRNHYAVAVDYNV
CCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEEECCEEEEEEEEC
DNKSTTPLELTLFGQLKQTTELPKHRDTGSNNFALHTFRGAAYSSSDDKYQKYAFDKDEN
CCCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCC
LSVTTQGGWVAMLQQYFATAWVPATQGSNTFYTAKPGDNLSTIGFKSTPVVVQPGAQQQL
EEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEECCCCCCCEEECCCCCHHC
NATLWVGPELQDQMAQLAPHLDLTVDYGWLWFISQPLFKLLKFIHGFIGNWGFSIIIITF
CEEEEECCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IVRGIMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDKQRMSQEMMALYKSEKVNPLGGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHH
LPLVIQMPIFLALYYMLMGSVELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSP
HHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHCCC
TTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTILQQQLIYRGLEKRGLHSR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DKKKT
CCCCH
>Mature Secondary Structure
MDSQRNLLLIALLFVSFMIWQAWQTDNAPQPVAQTTQQTSNPATGDAASSAVPASGQGKL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEE
ITVNTDVLSLTINTRGGDIEQAKLLAYPDTLGSSTPFQLLETTPAFVYQAQSGLTGRNGP
EEEECCEEEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHCCHHHEEECCCCCCCCCCC
DNPANGERPLFQAAQDSYTLPEGQEELRIPLTFTGKDGAIYTKTFVLKRNHYAVAVDYNV
CCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEEECCEEEEEEEEC
DNKSTTPLELTLFGQLKQTTELPKHRDTGSNNFALHTFRGAAYSSSDDKYQKYAFDKDEN
CCCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCC
LSVTTQGGWVAMLQQYFATAWVPATQGSNTFYTAKPGDNLSTIGFKSTPVVVQPGAQQQL
EEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEECCCCCCCEEECCCCCHHC
NATLWVGPELQDQMAQLAPHLDLTVDYGWLWFISQPLFKLLKFIHGFIGNWGFSIIIITF
CEEEEECCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IVRGIMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDKQRMSQEMMALYKSEKVNPLGGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHH
LPLVIQMPIFLALYYMLMGSVELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSP
HHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHCCC
TTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTILQQQLIYRGLEKRGLHSR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DKKKT
CCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA