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The map label for this gene is yieH [H]

Identifier: 157368269

GI number: 157368269

Start: 18610

End: 19275

Strand: Reverse

Name: yieH [H]

Synonym: Spro_0020

Alternate gene names: 157368269

Gene position: 19275-18610 (Counterclockwise)

Preceding gene: 157368271

Following gene: NA

Centisome position: 0.35

GC content: 56.46

Gene sequence:

>666_bases
ATGAACCAAATTGACTGTATTTTGTTTGATTGCGACGGCACGCTGGTGGACAGCGAAGTGCTGTGCAGCAAAGCCTATGT
GCACATGTTTGCCCACTATGGCATTCACCTTTCGCTGGACGAGGTATTCAGAAAGTACAAAGGGGTAAAGCTGTACGAAA
TTATCGAACAGGTTAATGCGGAGCACGGCGTCGCCTTGCCGAAGGAAGAACTGGAGCCTTTATACCGTCAGGAAGTGGCC
CGTCTGTTTGACAGCGAACTGCAGCAGATTGCCGGTGCGCGCGAGCTGCTGGCGCAGGTGACAGTACCAATGTGTACCGT
GTCTAACGGCCCGGTCAGCAAAATGCAGCACTCGCTCGGCCTGACCGACATGCTCCACTATTTTGATGACCGGTTGTTCA
GCGGCTATGACATTCAGCGCTGGAAACCGGACCCGGCGATCGTGTTTCACGCCGCCGAAAAAATGCGGGTGCCGGTGGAG
CGTTGCATCCTGGTGGACGACTCCGCTGCTGGTGCGCAGGCGGGGATCGCCGCCGGGATCCCAGTATTTTACTTCTGCGC
CGATCCGCACAACCAACCGATCGACCATCCGCTGGTCACCGCATTCGACGATTTGGCGCAATTACCAGCGCTGTGGCGTG
AACGCGGCTGGCAGTTGACTAGCTAG

Upstream 100 bases:

>100_bases
TTCCTGAGATTGATCGGCAATCCGTGATTCTGGGGTCGCAATCCTGCCTGATGCGGTTAAAGTGGCATTATCACCGCATA
ACCGAAGGACACGGCCCCTG

Downstream 100 bases:

>100_bases
CCGGCAACGGCGGCTTATTGCGCCACCAGCGCCATGAGCGTTTCAACGCCCGGGTCTGCGGGCTAAAGCGGCGGTTGACC
GCATTGGCCAGCAGATCCAG

Product: 6-phosphogluconate phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNQIDCILFDCDGTLVDSEVLCSKAYVHMFAHYGIHLSLDEVFRKYKGVKLYEIIEQVNAEHGVALPKEELEPLYRQEVA
RLFDSELQQIAGARELLAQVTVPMCTVSNGPVSKMQHSLGLTDMLHYFDDRLFSGYDIQRWKPDPAIVFHAAEKMRVPVE
RCILVDDSAAGAQAGIAAGIPVFYFCADPHNQPIDHPLVTAFDDLAQLPALWRERGWQLTS

Sequences:

>Translated_221_residues
MNQIDCILFDCDGTLVDSEVLCSKAYVHMFAHYGIHLSLDEVFRKYKGVKLYEIIEQVNAEHGVALPKEELEPLYRQEVA
RLFDSELQQIAGARELLAQVTVPMCTVSNGPVSKMQHSLGLTDMLHYFDDRLFSGYDIQRWKPDPAIVFHAAEKMRVPVE
RCILVDDSAAGAQAGIAAGIPVFYFCADPHNQPIDHPLVTAFDDLAQLPALWRERGWQLTS
>Mature_221_residues
MNQIDCILFDCDGTLVDSEVLCSKAYVHMFAHYGIHLSLDEVFRKYKGVKLYEIIEQVNAEHGVALPKEELEPLYRQEVA
RLFDSELQQIAGARELLAQVTVPMCTVSNGPVSKMQHSLGLTDMLHYFDDRLFSGYDIQRWKPDPAIVFHAAEKMRVPVE
RCILVDDSAAGAQAGIAAGIPVFYFCADPHNQPIDHPLVTAFDDLAQLPALWRERGWQLTS

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=221, Percent_Identity=66.9683257918552, Blast_Score=323, Evalue=7e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24905; Mature: 24905

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIDCILFDCDGTLVDSEVLCSKAYVHMFAHYGIHLSLDEVFRKYKGVKLYEIIEQVNA
CCCCEEEEECCCCCEECHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCHHHHHHHHHCC
EHGVALPKEELEPLYRQEVARLFDSELQQIAGARELLAQVTVPMCTVSNGPVSKMQHSLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHCC
LTDMLHYFDDRLFSGYDIQRWKPDPAIVFHAAEKMRVPVERCILVDDSAAGAQAGIAAGI
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEECHHHHCCCHHHEEEECCCCCCCCCCHHCCC
PVFYFCADPHNQPIDHPLVTAFDDLAQLPALWRERGWQLTS
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNQIDCILFDCDGTLVDSEVLCSKAYVHMFAHYGIHLSLDEVFRKYKGVKLYEIIEQVNA
CCCCEEEEECCCCCEECHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCHHHHHHHHHCC
EHGVALPKEELEPLYRQEVARLFDSELQQIAGARELLAQVTVPMCTVSNGPVSKMQHSLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHCC
LTDMLHYFDDRLFSGYDIQRWKPDPAIVFHAAEKMRVPVERCILVDDSAAGAQAGIAAGI
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEECHHHHCCCHHHEEEECCCCCCCCCCHHCCC
PVFYFCADPHNQPIDHPLVTAFDDLAQLPALWRERGWQLTS
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]