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The map label for this gene is katG [H]

Identifier: 157163419

GI number: 157163419

Start: 4162468

End: 4164648

Strand: Direct

Name: katG [H]

Synonym: EcHS_A4176

Alternate gene names: 157163419

Gene position: 4162468-4164648 (Clockwise)

Preceding gene: 157163418

Following gene: 157163420

Centisome position: 89.64

GC content: 55.71

Gene sequence:

>2181_bases
ATGAGCACGTCAGACGATATCCATAACACCACAGCCACTGGCAAATGCCCGTTCCATCAGGGCGGTCACGACCAGAGTGC
GGGGGCGGGCACAACCACTCGCGACTGGTGGCCAAATCAACTTCGTGTTGACCTGTTAAACCAACATTCTAATCGTTCTA
ACCCACTGGGTGAGGACTTTGACTACCGCAAAGAATTCAGCAAATTAGATTACTACGGCCTGAAAAAAGATCTGAAAGCC
CTGTTGACAGAATCTCAACCGTGGTGGCCAGCCGACTGGGGCAGTTACGCCGGTCTGTTTATTCGTATGGCCTGGCACGG
CGCGGGGACTTACCGTTCAATCGATGGACGCGGTGGCGCGGGTCGTGGTCAGCAACGTTTTGCACCGCTGAACTCCTGGC
CGGATAACGTAAGCCTCGATAAAGCGCGTCGCCTGTTGTGGCCAATCAAACAGAAATATGGTCAGAAAATCTCCTGGGCC
GACCTGTTTATCCTCGCGGGTAACGTGGCGCTAGAAAACTCCGGCTTCCGTACCTTCGGTTTTGGTGCCGGTCGTGAAGA
CGTCTGGGAACCGGATCTGGATGTTAACTGGGGTGATGAAAAAGCCTGGCTGACTCACCGTCATCCGGAAGCGCTGGCGA
AAGCACCGCTGGGTGCAACCGAGATGGGTCTGATTTACGTTAACCCGGAAGGCCCGGATCACAGCGGCGAACCGCTTTCT
GCGGCAGCAGCTATCCGCGCGACCTTCGGCAACATGGGCATGAACGACGAAGAAACCGTGGCGCTGATTGCGGGTGGTCA
TACGCTGGGTAAAACCCACGGTGCCGGTCCGACATCAAATGTAGGTCCTGATCCAGAAGCTGCACCGATTGAAGAACAAG
GTTTAGGTTGGGCGAGCACTTACGGCAGCGGCGTTGGCGCAGATGCCATTACCTCTGGTCTGGAAGTAGTCTGGACCCAG
ACGCCGACCCAGTGGAGCAACTATTTCTTCGAGAACCTGTTCAAGTATGAGTGGGTACAGACCCGCAGCCCGGCTGGCGC
AATCCAGTTCGAAGCGGTAGACGCACCGGAAATTATCCCGGATCCGTTTGATCCGTCGAAGAAACGTAAACCGACAATGC
TGGTGACCGACCTGACGCTGCGTTTTGATCCTGAGTTCGAGAAGATCTCTCGTCGTTTCCTCAACGATCCGCAGGCGTTC
AACGAAGCCTTTGCCCGTGCCTGGTTCAAACTGACGCACAGGGATATGGGGCCGAAATCTCGCTACATCGGGCCGGAAGT
GCCGAAAGAAGATCTGATCTGGCAAGATCCGCTGCCGCAGCCGATCTACAACCCGACCGAGCAGGACATTATCGATCTGA
AATTCGCGATTGCGGATTCTGGTCTGTCTGTTAGTGAGCTGGTATCGGTGGCCTGGGCATCTGCTTCTACCTTCCGTGGT
GGCGACAAACGCGGTGGTGCCAACGGTGCGCGTCTGGCATTAATGCCGCAGCGCGACTGGGATGTGAACGCCGCAGCCGT
TCGTGCTCTGCCTGTTCTGGAGAAAATCCAGAAAGAGTCTGGTAAAGCCTCGCTGGCGGATATCATAGTGCTGGCTGGTG
TGGTTGGTGTTGAGAAAGCCGCAAGCGCCGCAGGTTTGAGCATTCATGTACCGTTTGCGCCGGGTCGCGTTGATGCGCGT
CAGGATCAGACTGACATTGAGATGTTTGAGCTGCTGGAGCCAATTGCTGACGGTTTCCGTAACTATCGCGCTCGTCTGGA
CGTTTCCACCACCGAGTCACTGCTGATCGACAAAGCACAGCAACTGACGCTGACCGCGCCGGAAATGACTGCGCTGGTGG
GCGGCATGCGTGTACTGGGTGCCAACTTCGATGGCAGCAAAAACGGCGTCTTCACTGACCGCGTTGGCGTATTGAGCAAT
GACTTCTTCGTGAACTTGCTGGATATGCGTTACGAGTGGAAAGCGACCGACGAATCGAAAGAGCTGTTCGAAGGCCGTGA
CCGTGAAACCGGCGAAGTGAAATTTACGGCCAGCCGTGCGGATCTGGTTTTTGGTTCTAACTCCGTCCTGCGTGCGGTGG
CGGAAGTTTACGCCAGTAGCGATGCCCACGAGAAGTTTGTTAAAGACTTCGTGGCGGCATGGGTGAAAGTGATGAACCTC
GACCGTTTCGACCTGCTGTAA

Upstream 100 bases:

>100_bases
TATGTAAGATCTCAACTATCGCATCCGTGGATTAATTCAATTATAACTTCTCTCTAACGCTGTGTATCGTAACGGTAACA
CTGTAGAGGGGAGCACATTG

Downstream 100 bases:

>100_bases
TCTGACCCCGTTCAGCGGCTGCTTGCTGGCAGTCGCTGAACGTTCTTTACCAGCGTATAGTGGGCGAACGAAAACTACAC
ACTGGATCTCTCATGTCTGC

Product: catalase/peroxidase HPI

Products: NA

Alternate protein names: CP 1; Peroxidase/catalase 1 [H]

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKA
LLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLS
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQ
TPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAF
NEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRG
GDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDAR
QDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSN
DFFVNLLDMRYEWKATDESKELFEGRDRETGEVKFTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNL
DRFDLL

Sequences:

>Translated_726_residues
MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKA
LLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLS
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQ
TPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAF
NEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRG
GDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDAR
QDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSN
DFFVNLLDMRYEWKATDESKELFEGRDRETGEVKFTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNL
DRFDLL
>Mature_725_residues
STSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKAL
LTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWAD
LFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSA
AAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQT
PTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFN
EAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRGG
DKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQ
DQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSND
FFVNLLDMRYEWKATDESKELFEGRDRETGEVKFTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLD
RFDLL

Specific function: Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity [H]

COG id: COG0376

COG function: function code P; Catalase (peroxidase I)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peroxidase family. Peroxidase/catalase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790378, Length=726, Percent_Identity=100, Blast_Score=1484, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000763
- InterPro:   IPR010255
- InterPro:   IPR002016
- InterPro:   IPR019794
- InterPro:   IPR019793 [H]

Pfam domain/function: PF00141 peroxidase [H]

EC number: =1.11.1.6; =1.11.1.7 [H]

Molecular weight: Translated: 80024; Mature: 79893

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00435 PEROXIDASE_1 ; PS00436 PEROXIDASE_2 ; PS50873 PEROXIDASE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
DYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCCEEECCCCCCC
GRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCEEEC
FGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLS
CCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHH
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWAST
HHHHHHHHHCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCHHH
YGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIP
CCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
DPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKS
CCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
RYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRG
CCCCCCCCHHCCCCCCCCCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHCCHHCCC
GDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKA
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ASAAGLSIHVPFAPGRVDARQDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQ
HCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCH
QLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESK
HEEEECHHHHHHHCCHHEEECCCCCCCCCEEECCCCCCCCCCEEEEECCEEEECCCCCHH
ELFEGRDRETGEVKFTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNL
HHHCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
DRFDLL
CHHHCC
>Mature Secondary Structure 
STSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
DYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCCEEECCCCCCC
GRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCEEEC
FGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLS
CCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHH
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWAST
HHHHHHHHHCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCHHH
YGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIP
CCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
DPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKS
CCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
RYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRG
CCCCCCCCHHCCCCCCCCCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHCCHHCCC
GDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKA
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ASAAGLSIHVPFAPGRVDARQDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQ
HCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCH
QLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESK
HEEEECHHHHHHHCCHHEEECCCCCCCCCEEECCCCCCCCCCEEEEECCEEEECCCCCHH
ELFEGRDRETGEVKFTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNL
HHHCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
DRFDLL
CHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11258796; 11206551 [H]