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The map label for this gene is frvR [H]

Identifier: 157163369

GI number: 157163369

Start: 4116294

End: 4118048

Strand: Reverse

Name: frvR [H]

Synonym: EcHS_A4125

Alternate gene names: 157163369

Gene position: 4118048-4116294 (Counterclockwise)

Preceding gene: 157163370

Following gene: 157163366

Centisome position: 88.68

GC content: 50.09

Gene sequence:

>1755_bases
ATGCTAAACGAACGCCAGTTAAAGATTGTCGATCTGCTGGAGCAACAGCCGCGCACGCCTGGCGAGCTGGCGCAACAGAC
TGGCGTTTCAGGCAGGACCATCCTGCGTGATATTGACTATCTCAACTTCACCCTTAACGGCAAAGCCCGCATTTTCGCCA
GTGGCAGTGCGGGCTATCAGCTGGAAATCTTCGAGCGCCGCAGCTTTTTTCAGTTGCTGCAAAAGCACGATAACGACGAT
CGGCTGCTGGCGCTGTTATTACTGAATACTTTCACTCCCCGTGCGCAACTCGCCTCGGCGCTTAATTTGCCAGAAACGTG
GGTAGCAGAGCGTCTGCCCCGGTTAAAACAGCGTTATGAACGCACTTGTTGCCTGGCCAGCCGCCCTGGTTTGGGCCATT
TCATTGATGAGACAGAAGAGAAACGCGTTATCTTGCTGGCGAACTTGCTGCGCAAAGATCCGTTTTTAATTCCGCTGGCG
GGCATAACACGAGACAACCTTCAGCATTTATCCACGGCCTGCGACAACCAACACCGCTGGCCGCTCATGCAGGGTGATTA
TCTCTCCAGCCTGATTCTGGCGATTTACGCCCTGCGTAATCAACTGACCGATGAGTGGCCGCAATATCCCGGTGACGAGA
TAAAACAAATCGTTGAACAAAGCGGCATGTTTCTTGGTGATAACGCTGTAAGAACCCTGACAGGTTTGATAGAGAAACAG
CATCAGCAAGCGCAGATAATTTCTGCCGATAATGTGCAGCGGTTGCTGCAAAGGGTGCCGGGCATCGCGTCATTGAATAT
TATTGATACGCGGCTGGTTGAGAACATTACCGGGCATTTATTACGTTGCCTTGCCGCACCAGTGTGGATTGCTGAGCACC
GCCAAAGCAGCATGAATAACCTGAAAGCAGCCTGGCCTGCGGCCTTTGATATGAGTCTGCACTTTATTACGCTACTGCGT
GAACAGCTCGATATTCCCCTTTTCGACAGCGATCTGCTCGGTTTGTATTTTGCCTGTGCGCTGGAGCGGCATCAAAACGA
ACGCCAGCCGATCATTTTGCTCTCGGACCAGAACGCGATTGCCACCATTAATCAGCTCGCCATTGAGCGCGATGTTTTAA
ATTGTCGGGTGATTATTGCCCGTAGCTTAAGCGAGCTTGTTGCCATTCGCGAAGAGATTGAGCCGTTATTGATCATTAAC
AACAGCCATTATTTACTGGATGACGCGGTAAATAATTACATCACCGTAAAAAATATCATTACGGCTGCCGGTATCGAACA
AATAAAACATTTTCTGGCGACGGCATTTATTCGCCAGCAACCGGAGCGTTTTTTCTCTGCCCCCGGAAGTTTTCATTATT
CGAATGTACGCGGTGAAAGCTGGCAACATATTACCCGGCAAATTTGTGCGCAATTAGTCGCACAACACCATATTACCGCC
GATGAAGCACAACGCATCATCGCCCGCGAAGGCGAAGGTGAAGGTGAAAACCTGATTGTTAATCGCCTCGCCATCCCACA
TTGCTGGAGCGAACAGGAGCGACGTTTTCGTGGATTTTTTATTACCCTCGCCCAACCAGTTGAGGTGAATAACGAAGTCA
TTAACCATGTCTTGATCGCCTGCGCCGCCGCCGATGCGCGTCATGAGCTAAAAATATTTAGCTATCTGGCAAGCATATTG
TGTCAGCATCCGGCGGAGATTATTGCCGGGTTAACAGGATATGAGGCATTTATGGAGTTACTTCACAAGGGGTGA

Upstream 100 bases:

>100_bases
AAGCCGATTACGAAGCTCTGCTCACGCTGATACGGGGTTTTCTGACGACCTTAACTGCGGAGAAAGTCAACGCGTTTAGC
CAGTTCCGTCAGGTGGATTA

Downstream 100 bases:

>100_bases
ACTGTGTCGGATGCGCCGCATCCGACACTGCATTTATCATCAAAAACGTTTAACGCAGGCTATTATAGTCATCAACCATT
TCGTTGTACTCGCGTAATGC

Product: putative frv operon regulatory protein

Products: NA

Alternate protein names: Putative phosphotransferase EIIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARIFASGSAGYQLEIFERRSFFQLLQKHDNDD
RLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLA
GITRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGMFLGDNAVRTLTGLIEKQ
HQQAQIISADNVQRLLQRVPGIASLNIIDTRLVENITGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLR
EQLDIPLFDSDLLGLYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLNCRVIIARSLSELVAIREEIEPLLIIN
NSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
DEAQRIIAREGEGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASIL
CQHPAEIIAGLTGYEAFMELLHKG

Sequences:

>Translated_584_residues
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARIFASGSAGYQLEIFERRSFFQLLQKHDNDD
RLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLA
GITRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGMFLGDNAVRTLTGLIEKQ
HQQAQIISADNVQRLLQRVPGIASLNIIDTRLVENITGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLR
EQLDIPLFDSDLLGLYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLNCRVIIARSLSELVAIREEIEPLLIIN
NSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
DEAQRIIAREGEGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASIL
CQHPAEIIAGLTGYEAFMELLHKG
>Mature_584_residues
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARIFASGSAGYQLEIFERRSFFQLLQKHDNDD
RLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLA
GITRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGMFLGDNAVRTLTGLIEKQ
HQQAQIISADNVQRLLQRVPGIASLNIIDTRLVENITGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLR
EQLDIPLFDSDLLGLYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLNCRVIIARSLSELVAIREEIEPLLIIN
NSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
DEAQRIIAREGEGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASIL
CQHPAEIIAGLTGYEAFMELLHKG

Specific function: Could be involved in the regulation of the transcription of the FRV operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790331, Length=584, Percent_Identity=98.458904109589, Blast_Score=1160, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF00359 PTS_EIIA_2 [H]

EC number: NA

Molecular weight: Translated: 66367; Mature: 66367

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARIFASGSAGYQ
CCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHCCEEEEEECCCEEEEECCCCCCE
LEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYE
EEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
RTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLAGITRDNLQHLSTACDNQHRW
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCC
PLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGMFLGDNAVRTLTGLIEKQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHH
HQQAQIISADNVQRLLQRVPGIASLNIIDTRLVENITGHLLRCLAAPVWIAEHRQSSMNN
HHHHHHHCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAWPAAFDMSLHFITLLREQLDIPLFDSDLLGLYFACALERHQNERQPIILLSDQNAI
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
ATINQLAIERDVLNCRVIIARSLSELVAIREEIEPLLIINNSHYLLDDAVNNYITVKNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEHHHHCCEEEHHHHH
TAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
HHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCH
DEAQRIIAREGEGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVINHVLIA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCEEEEEECCCCCCHHHHHHHHHHH
CAAADARHELKIFSYLASILCQHPAEIIAGLTGYEAFMELLHKG
HHHHCCHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARIFASGSAGYQ
CCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHCCEEEEEECCCEEEEECCCCCCE
LEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYE
EEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
RTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLAGITRDNLQHLSTACDNQHRW
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCC
PLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGMFLGDNAVRTLTGLIEKQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHH
HQQAQIISADNVQRLLQRVPGIASLNIIDTRLVENITGHLLRCLAAPVWIAEHRQSSMNN
HHHHHHHCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAWPAAFDMSLHFITLLREQLDIPLFDSDLLGLYFACALERHQNERQPIILLSDQNAI
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
ATINQLAIERDVLNCRVIIARSLSELVAIREEIEPLLIINNSHYLLDDAVNNYITVKNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEHHHHCCEEEHHHHH
TAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
HHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCH
DEAQRIIAREGEGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVINHVLIA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCEEEEEECCCCCCHHHHHHHHHHH
CAAADARHELKIFSYLASILCQHPAEIIAGLTGYEAFMELLHKG
HHHHCCHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8019415 [H]