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The map label for this gene is yihV [H]

Identifier: 157163348

GI number: 157163348

Start: 4094590

End: 4095486

Strand: Reverse

Name: yihV [H]

Synonym: EcHS_A4103

Alternate gene names: 157163348

Gene position: 4095486-4094590 (Counterclockwise)

Preceding gene: 157163359

Following gene: 157163347

Centisome position: 88.2

GC content: 50.5

Gene sequence:

>897_bases
ATGACCAAAATTGCATGCGTGGGTATCACAGTTCAGGACAGGATTTATTCTTTGCTCACTCTGCCGGATGGCGGCGGAAA
ATATCAGGCAAATCATTATCTTGAGATTGGTGGCGGCCCGGCAGCAACAGCCGCTGTTGCAATCGCAAAGCTTGGCGTGG
AGGTTGATTTCATCGGTCGCGTCGGCGATGACAGTTGTGGAAATACCTTACTTGCAGAACTTGAGGGTTGGGGCGTCAAT
ACCGCATTTTGCCGCCGATATCCTAACGCCCGTTCATCGCAATCAGCGATCCTCGTTGATCAGCATGGCGAACGGATTAT
CGTTAATTATCCAAGTCCCGATCTCGGTACTGATGCCGAATGGTTAGAAGCGATCGATTTCTCTCGTTATGATCTGATTC
TGGCCGATGTTCGCTGGCATAGCGGTACTGAAAAAGCATTCTCGCTAGCGCGTCTTGCGGGTGTGACAACGCTTTTAGAC
GCCGATATGACACCGCAGGATATTTCTCCACTTGTCGCGCTTGCCGATCACGCCGTGTTCTCAACACCAGGGCTGAAACG
CATGACTGGCCTGCAGTCACCTGAAGAAGGTTTGTTCCAGGCAACGACACAAACAGCAGGTAAAGTGTATGTTACGCTGG
GTTCTGAAGGATCGTTGTGGATTGAAGATGGTCATTTGTGTCAACAGGAGGCATTTTCTGTCAATGTGGTTGATACCACT
GGAGCAGGCGATGTTTTTCACGGCGCACTCGCGGTAGCGTTGGCAGAAAAAATGCCAACAAAAGAGGCTATTCGTTTTGC
CAGTGCGGTTGCCGCGATGAAATGTACCCAGCCTGGCGGTCGGGCCGGCATTCCTAATCGTGAGCAAACCGAATCATTTT
TGTCACTTTATGCGTAA

Upstream 100 bases:

>100_bases
TTGTAATTTATGTTCAAAAACACGACACGCATCACTAATTTGATCATTTGTGTCATTTAAATTGACCGAAGACGACAAAA
TTAAACAGGACAAGACAAAT

Downstream 100 bases:

>100_bases
AATGGTAAACATCTACCGAGGAGGGGCAAGGGAGTATTCATGAGTATCATCGAAGTGACAGGTAATCCACGCCATGACCA
ACTCGTTCATCTAATCGCAG

Product: PfkB family kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTKIACVGITVQDRIYSLLTLPDGGGKYQANHYLEIGGGPAATAAVAIAKLGVEVDFIGRVGDDSCGNTLLAELEGWGVN
TAFCRRYPNARSSQSAILVDQHGERIIVNYPSPDLGTDAEWLEAIDFSRYDLILADVRWHSGTEKAFSLARLAGVTTLLD
ADMTPQDISPLVALADHAVFSTPGLKRMTGLQSPEEGLFQATTQTAGKVYVTLGSEGSLWIEDGHLCQQEAFSVNVVDTT
GAGDVFHGALAVALAEKMPTKEAIRFASAVAAMKCTQPGGRAGIPNREQTESFLSLYA

Sequences:

>Translated_298_residues
MTKIACVGITVQDRIYSLLTLPDGGGKYQANHYLEIGGGPAATAAVAIAKLGVEVDFIGRVGDDSCGNTLLAELEGWGVN
TAFCRRYPNARSSQSAILVDQHGERIIVNYPSPDLGTDAEWLEAIDFSRYDLILADVRWHSGTEKAFSLARLAGVTTLLD
ADMTPQDISPLVALADHAVFSTPGLKRMTGLQSPEEGLFQATTQTAGKVYVTLGSEGSLWIEDGHLCQQEAFSVNVVDTT
GAGDVFHGALAVALAEKMPTKEAIRFASAVAAMKCTQPGGRAGIPNREQTESFLSLYA
>Mature_297_residues
TKIACVGITVQDRIYSLLTLPDGGGKYQANHYLEIGGGPAATAAVAIAKLGVEVDFIGRVGDDSCGNTLLAELEGWGVNT
AFCRRYPNARSSQSAILVDQHGERIIVNYPSPDLGTDAEWLEAIDFSRYDLILADVRWHSGTEKAFSLARLAGVTTLLDA
DMTPQDISPLVALADHAVFSTPGLKRMTGLQSPEEGLFQATTQTAGKVYVTLGSEGSLWIEDGHLCQQEAFSVNVVDTTG
AGDVFHGALAVALAEKMPTKEAIRFASAVAAMKCTQPGGRAGIPNREQTESFLSLYA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=288, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI5670342, Length=288, Percent_Identity=23.9583333333333, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87082343, Length=297, Percent_Identity=67.003367003367, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=28.0936454849498, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081971, Length=280, Percent_Identity=24.6428571428571, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=292, Percent_Identity=29.4520547945205, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24662680, Length=296, Percent_Identity=23.9864864864865, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24583886, Length=291, Percent_Identity=24.7422680412371, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 31681; Mature: 31550

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIACVGITVQDRIYSLLTLPDGGGKYQANHYLEIGGGPAATAAVAIAKLGVEVDFIGR
CCEEEEEEEEEHHCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEEC
VGDDSCGNTLLAELEGWGVNTAFCRRYPNARSSQSAILVDQHGERIIVNYPSPDLGTDAE
CCCCCCCCCEEEHHCCCCCCHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHH
WLEAIDFSRYDLILADVRWHSGTEKAFSLARLAGVTTLLDADMTPQDISPLVALADHAVF
HHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
STPGLKRMTGLQSPEEGLFQATTQTAGKVYVTLGSEGSLWIEDGHLCQQEAFSVNVVDTT
CCCCHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCHHHCEEEEEEECC
GAGDVFHGALAVALAEKMPTKEAIRFASAVAAMKCTQPGGRAGIPNREQTESFLSLYA
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TKIACVGITVQDRIYSLLTLPDGGGKYQANHYLEIGGGPAATAAVAIAKLGVEVDFIGR
CEEEEEEEEEHHCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEEC
VGDDSCGNTLLAELEGWGVNTAFCRRYPNARSSQSAILVDQHGERIIVNYPSPDLGTDAE
CCCCCCCCCEEEHHCCCCCCHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHH
WLEAIDFSRYDLILADVRWHSGTEKAFSLARLAGVTTLLDADMTPQDISPLVALADHAVF
HHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
STPGLKRMTGLQSPEEGLFQATTQTAGKVYVTLGSEGSLWIEDGHLCQQEAFSVNVVDTT
CCCCHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCHHHCEEEEEEECC
GAGDVFHGALAVALAEKMPTKEAIRFASAVAAMKCTQPGGRAGIPNREQTESFLSLYA
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]